Works by Ouyang, Defang

Results: 56

In Vitro and In Vivo Evaluation of Two Extended Release Preparations of Combination Metformin and Glipizide.

Published in:

Drug Development & Industrial Pharmacy, 2005, v. 31, n. 7, p. 677, doi. 10.1080/03639040500216410

By:

Defang, Ouyang;
Shufang, Nie;
Wei, Li;
Hong, Guo;
Hui, Liu;
Weisan, Pan

Publication type:

Article

Artificial intelligence-driven rational design of ionizable lipids for mRNA delivery.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-55072-6

By:

Wang, Wei;
Chen, Kepan;
Jiang, Ting;
Wu, Yiyang;
Wu, Zheng;
Ying, Hang;
Yu, Hang;
Lu, Jing;
Lin, Jinzhong;
Ouyang, Defang

Publication type:

Article

Traditional Chinese medicine injections: where we are after 80-year development.

Published in:

Chinese Medicine, 2022, v. 17, n. 1, p. 1, doi. 10.1186/s13020-022-00681-w

By:

Zheng, Wenwen;
Wu, Yiyang;
Gao, Hanlu;
Ouyang, Defang

Publication type:

Article

Harnessing the power of machine learning into tissue engineering: current progress and future prospects.

Published in:

Burns & Trauma, 2024, v. 12, n. 1, p. 1, doi. 10.1093/burnst/tkae053

By:

Wu, Yiyang;
Ding, Xiaotong;
Wang, Yiwei;
Ouyang, Defang

Publication type:

Article

Synthesis of Carbon Onion and Its Application as a Porous Carrier for Amorphous Drug Delivery.

Published in:

Crystals (2073-4352), 2020, v. 10, n. 4, p. 281, doi. 10.3390/cryst10040281

By:

Miriyala, Nikhila;
Kirby, Daniel J.;
Cumont, Aude;
Zhang, Ruoying;
Shi, Baogui;
Ouyang, Defang;
Ye, Haitao

Publication type:

Article

Combining MSC Exosomes and Cerium Oxide Nanocrystals for Enhanced Dry Eye Syndrome Therapy.

Published in:

Pharmaceutics, 2023, v. 15, n. 9, p. 2301, doi. 10.3390/pharmaceutics15092301

By:

Tian, Ying;
Zhang, Yiquan;
Zhao, Jiawei;
Luan, Fuxiao;
Wang, Yingjie;
Lai, Fan;
Ouyang, Defang;
Tao, Yong

Publication type:

Article

Molecular Dynamics Simulation of Drug Solubilization Behavior in Surfactant and Cosolvent Injections.

Published in:

Pharmaceutics, 2022, v. 14, n. 11, p. 2366, doi. 10.3390/pharmaceutics14112366

By:

He, Meiqi;
Zheng, Wenwen;
Wang, Nannan;
Gao, Hanlu;
Ouyang, Defang;
Huang, Zunnan

Publication type:

Article

Emerging Artificial Intelligence (AI) Technologies Used in the Development of Solid Dosage Forms.

Published in:

Pharmaceutics, 2022, v. 14, n. 11, p. 2257, doi. 10.3390/pharmaceutics14112257

By:

Jiang, Junhuang;
Ma, Xiangyu;
Ouyang, Defang;
Williams III, Robert O.

Publication type:

Article

Development of Arteannuin B Sustained-Release Microspheres for Anti-Tumor Therapy by Integrated Experimental and Molecular Modeling Approaches.

Published in:

Pharmaceutics, 2021, v. 13, n. 8, p. 1236, doi. 10.3390/pharmaceutics13081236

By:

Wang, Yanqing;
Huang, Weijuan;
Wang, Nannan;
Ouyang, Defang;
Xiao, Lifeng;
Zhang, Sirui;
Ou, Xiaozheng;
He, Tingsha;
Yu, Rongmin;
Song, Liyan

Publication type:

Article

Molecular Interactions for the Curcumin-Polymer Complex with Enhanced Anti-Inflammatory Effects.

Published in:

Pharmaceutics, 2019, v. 11, n. 9, p. 442, doi. 10.3390/pharmaceutics11090442

By:

He, Yan;
Liu, Hongfei;
Bian, Wangqing;
Liu, Yue;
Liu, Xinyang;
Ma, Shijing;
Zheng, Xi;
Du, Zhiyun;
Zhang, Kun;
Ouyang, Defang

Publication type:

Article

Hydrotalcite Intercalated siRNA: Computational Characterization of the Interlayer Environment.

Published in:

Pharmaceutics, 2012, v. 4, n. 2, p. 296, doi. 10.3390/pharmaceutics4020296

By:

Hong Zhang;
Defang Ouyang;
Murthy, Vinuthaa;
Yunyi Wong;
Zhiping Xu;
Smith, Sean C.

Publication type:

Article

Engineering hyaluronic acid-based nanoassemblies for monoclonal antibody delivery – design, characterization, and biological insights.

Published in:

Nano Research, 2024, v. 17, n. 10, p. 9111, doi. 10.1007/s12274-024-6826-8

By:

López-Estévez, Ana M.;
Zhang, Y.;
Medel, María;
Arriaga, Iker;
Sanjurjo, Lucía;
Huck-Iriart, Cristian;
Abrescia, Nicola G. A.;
Vicent, María J.;
Ouyang, Defang;
Torres, Dolores;
Alonso, María José

Publication type:

Article

Prediction of small-molecule compound solubility in organic solvents by machine learning algorithms.

Published in:

Journal of Cheminformatics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13321-021-00575-3

By:

Ye, Zhuyifan;
Ouyang, Defang

Publication type:

Article

Combining High-Throughput Screening and Machine Learning to Predict the Formation of Both Binary and Ternary Amorphous Solid Dispersion Formulations for Early Drug Discovery and Development.

Published in:

Pharmaceutical Research, 2025, v. 42, n. 4, p. 697, doi. 10.1007/s11095-025-03853-z

By:

Lu, Tianshu;
Wu, Yiyang;
Xiong, Ping;
Zhong, Hao;
Ding, Yang;
Li, Haifeng;
Ouyang, Defang

Publication type:

Article

PBPK/PD Modeling of Nifedipine for Precision Medicine in Pregnant Women: Enhancing Clinical Decision-Making for Optimal Drug Therapy.

Published in:

Pharmaceutical Research, 2024, v. 41, n. 1, p. 63, doi. 10.1007/s11095-023-03638-2

By:

Liu, Xinyang;
Wang, Wei;
Chen, Jingsi;
Chen, Dunjin;
Tao, Yong;
Ouyang, Defang

Publication type:

Article

Physiologically Based Pharmacokinetic Modeling for Multiple Oral Administration Labetalol in Pregnant Women.

Published in:

Pharmaceutical Research, 2023, v. 40, n. 7, p. 1765, doi. 10.1007/s11095-023-03523-y

By:

Song, Yudi;
Wang, Wei;
Liu, Xinyang;
Chen, Jingsi;
Chen, Dunjin;
Wang, Xiaoyi;
Li, Wei;
Ouyang, Defang

Publication type:

Article

Prediction of Free Drug Absorption in Cyclodextrin Formulation by a Modified Physiologically Based Pharmacokinetic Model and Phase Solubility 3-D Surface Graph.

Published in:

Pharmaceutical Research, 2021, v. 38, n. 7, p. 1157, doi. 10.1007/s11095-021-03071-3

By:

Wang, Wei;
Ouyang, Defang

Publication type:

Article

Synthesis of Carrier-Free Paclitaxel–Curcumin Nanoparticles: The Role of Curcuminoids.

Published in:

Bioengineering (Basel), 2022, v. 9, n. 12, p. 815, doi. 10.3390/bioengineering9120815

By:

Karaosmanoglu, Sena;
Zhang, Yunsen;
Zhou, Wenli;
Ouyang, Defang;
Chen, Xianfeng

Publication type:

Article

Investigation of molecular dissolution mechanism of ketoprofen binary and ternary solid dispersions by molecular dynamics simulations.

Published in:

Molecular Simulation, 2017, v. 43, n. 13, p. 1074, doi. 10.1080/08927022.2017.1321755

By:

Weijie Chen;
Defang Ouyang

Publication type:

Article

A Comprehensive Analysis of Biopharmaceutical Products Listed in the FDA’s Purple Book.

Published in:

AAPS PharmSciTech, 2024, v. 25, n. 5, p. 1, doi. 10.1208/s12249-024-02802-0

By:

Chen, Fuduan;
Zhong, Hao;
Chan, Ging;
Ouyang, Defang

Publication type:

Article

Predicting Glass-Forming Ability of Pharmaceutical Compounds by Using Machine Learning Technologies.

Published in:

AAPS PharmSciTech, 2023, v. 24, n. 5, p. 1, doi. 10.1208/s12249-023-02535-6

By:

Jiang, Junhuang;
Ouyang, Defang;
Williams III, Robert O.

Publication type:

Article

Development of a Highly Water-Soluble Lycopene Cyclodextrin Ternary Formulation by the Integrated Experimental and Modeling Techniques.

Published in:

AAPS PharmSciTech, 2021, v. 22, n. 1, p. 1, doi. 10.1208/s12249-020-01861-3

By:

Ma, Yan;
Zhong, Liuting;
Peng, Zhuo;
Liu, Xinyang;
Ouyang, Defang;
Guan, Shixia

Publication type:

Article

Insight into the Dissolution Molecular Mechanism of Ternary Solid Dispersions by Combined Experiments and Molecular Simulations.

Published in:

AAPS PharmSciTech, 2019, v. 20, n. 7, p. N.PAG, doi. 10.1208/s12249-019-1486-9

By:

Han, Run;
Huang, Tianhe;
Liu, Xinyang;
Yin, Xunqing;
Li, Haifeng;
Lu, Jiahong;
Ji, Yuanhui;
Sun, Huimin;
Ouyang, Defang

Publication type:

Article

Release Mechanism Between Ion Osmotic Pressure and Drug Release in Ionic-Driven Osmotic Pump Tablets (I).

Published in:

AAPS PharmSciTech, 2018, v. 19, n. 2, p. 803, doi. 10.1208/s12249-017-0900-4

By:

Cheng, Lizhen;
Gao, Siqi;
Ouyang, Defang;
Wang, Haiying;
Wang, Yongfei;
Pan, Weisan;
Yang, Xinggang

Publication type:

Article

Design and Evaluation of Hydrophilic Matrix System Containing Polyethylene Oxides for the Zero-Order Controlled Delivery of Water-Insoluble Drugs.

Published in:

AAPS PharmSciTech, 2017, v. 18, n. 1, p. 82, doi. 10.1208/s12249-016-0498-y

By:

Wang, Lijie;
Chen, Kai;
Wen, Haoyang;
Ouyang, Defang;
Li, Xue;
Gao, Yunyun;
Pan, Weisan;
Yang, Xinggang

Publication type:

Article

The role of hydrogen‐bond in solubilizing drugs by ionic liquids: A molecular dynamics and density functional theory study.

Published in:

AIChE Journal, 2022, v. 68, n. 6, p. 1, doi. 10.1002/aic.17672

By:

Huang, Yiping;
Ouyang, Defang;
Ji, Yuanhui

Publication type:

Article

How imidazolium‐based ionic liquids solubilize the poorly soluble ibuprofen? A theoretical study.

Published in:

AIChE Journal, 2020, v. 66, n. 5, p. 1, doi. 10.1002/aic.16940

By:

Huang, Yiping;
Ji, Yuanhui;
Zhang, Mao;
Ouyang, Defang

Publication type:

Article

Quercetin in Animal Models of Alzheimer’s Disease: A Systematic Review of Preclinical Studies.

Published in:

2020

By:

Xiao-Wen Zhang;
Jia-Yue Chen;
Defang Ouyang;
Jia-Hong Lu

Publication type:

Literature Review

The gap analysis between Chinese pharmaceutical academia and industry from 2000 to 2018.

Published in:

Scientometrics, 2020, v. 122, n. 2, p. 1113, doi. 10.1007/s11192-019-03313-7

By:

Zhong, Hao;
Ouyang, Defang

Publication type:

Article

Diversity of Pharmacy Faculty Members between UK and US.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2017, v. 51, n. 1, p. 20, doi. 10.5530/ijper.51.1.4

By:

Weixiang Zhang;
Yitao Wang;
Defang Ouyang

Publication type:

Article

Introducing enzymatic cleavage features and transfer learning realizes accurate peptide half-life prediction across species and organs.

Published in:

Briefings in Bioinformatics, 2024, v. 25, n. 4, p. 1, doi. 10.1093/bib/bbae350

By:

Tan, Xiaorong;
Liu, Qianhui;
Fang, Yanpeng;
Yang, Sen;
Chen, Fei;
Wang, Jianmin;
Ouyang, Defang;
Dong, Jie;
Zeng, Wenbin

Publication type:

Article

FormulationAI: a novel web-based platform for drug formulation design driven by artificial intelligence.

Published in:

Briefings in Bioinformatics, 2024, v. 25, n. 1, p. 1, doi. 10.1093/bib/bbad419

By:

Dong, Jie;
Wu, Zheng;
Xu, Huanle;
Ouyang, Defang

Publication type:

Article

Correction: Quantitative Analysis of Physical Stability Mechanisms of Amorphous Solid Dispersions by Molecular Dynamic Simulation.

Published in:

2025

By:

Zhong, Hao;
Lu, Tianshu;
Wang, Ruifeng;
Ouyang, Defang

Publication type:

Correction Notice

Quantitative Analysis of Physical Stability Mechanisms of Amorphous Solid Dispersions by Molecular Dynamic Simulation.

Published in:

AAPS Journal, 2025, v. 27, n. 1, p. 1, doi. 10.1208/s12248-024-01001-w

By:

Zhong, Hao;
Lu, Tianshu;
Wang, Ruifeng;
Ouyang, Defang

Publication type:

Article

Predicting liposome formulations by the integrated machine learning and molecular modeling approaches.

Published in:

Asian Journal of Pharmaceutical Sciences, 2023, v. 18, n. 3, p. 1, doi. 10.1016/j.ajps.2023.100811

By:

Run Han;
Zhuyifan Ye;
Yunsen Zhang;
Yaxin Cheng;
Ying Zheng;
Defang Ouyang

Publication type:

Article

Integrated computer-aided formulation design: A case study of andrographolide/ cyclodextrin ternary formulation.

Published in:

Asian Journal of Pharmaceutical Sciences, 2021, v. 16, n. 4, p. 494, doi. 10.1016/j.ajps.2021.03.006

By:

Haoshi Gao;
Yan Su;
Wei Wang;
Wei Xiong;
Xiyang Sun;
Yuanhui Ji;
Hua Yu;
Haifeng Li;
Defang Ouyang

Publication type:

Article

Investigation of molecular aggregation mechanism of glipizide/cyclodextrin complexation by combined experimental and molecular modeling approaches.

Published in:

Asian Journal of Pharmaceutical Sciences, 2019, v. 14, n. 6, p. 609, doi. 10.1016/j.ajps.2018.10.008

By:

Tianhe Huang;
Qianqian Zhao;
Yan Su;
Defang Ouyang

Publication type:

Article

Predicting oral disintegrating tablet formulations by neural network techniques.

Published in:

Asian Journal of Pharmaceutical Sciences, 2018, v. 13, n. 4, p. 336, doi. 10.1016/j.ajps.2018.01.003

By:

Run Han;
Yilong Yang;
Xiaoshan Li;
Defang Ouyang

Publication type:

Article

Investigating the molecular dissolution process of binary solid dispersions by molecular dynamics simulations.

Published in:

Asian Journal of Pharmaceutical Sciences, 2018, v. 13, n. 3, p. 248, doi. 10.1016/j.ajps.2017.07.011

By:

TengIan Chan;
Defang Ouyang

Publication type:

Article

Preparation and characterization of pelletized solid dispersion of resveratrol with mesoporous silica microparticles to improve dissolution by fluid-bed coating techniques.

Published in:

Asian Journal of Pharmaceutical Sciences, 2016, v. 11, n. 4, p. 528, doi. 10.1016/j.ajps.2015.10.030

By:

Jian Li;
Xiaoqing Miao;
Tongkai Chen;
Defang Ouyang;
Ying Zheng

Publication type:

Article

Interpretable machine learning methods for in vitro pharmaceutical formulation development.

Published in:

Food Frontiers, 2021, v. 2, n. 2, p. 195, doi. 10.1002/fft2.78

By:

Ye, Zhuyifan;
Yang, Wenmian;
Yang, Yilong;
Ouyang, Defang

Publication type:

Article

Academic Career Progression of Chinese-Origin Pharmacy Faculty Members in Western Countries.

Published in:

Pharmacy, 2018, v. 6, n. 4, p. 104, doi. 10.3390/pharmacy6040104

By:

Zhang, Weixiang;
Zhong, Hao;
Wang, Yitao;
Chan, Ging;
Hu, Yuanjia;
Hu, Hao;
Ouyang, Defang

Publication type:

Article

Progress in oncolytic viruses modified with nanomaterials for intravenous application.

Published in:

Cancer Biology & Medicine, 2023, v. 20, n. 11, p. 830, doi. 10.20892/j.issn.2095-3941.2023.0275

By:

Liting Chen;
Zhijun Ma;
Chen Xu;
Youbang Xie;
Defang Ouyang;
Shuhui Song;
Xiao Zhao;
Funan Liu

Publication type:

Article

Antibody Recognition of Human Epidermal Growth Factor Receptor-2 (HER2) Juxtamembrane Domain Enhances Anti-Tumor Response of Chimeric Antigen Receptor (CAR)-T Cells.

Published in:

Antibodies (2073-4468), 2024, v. 13, n. 2, p. 45, doi. 10.3390/antib13020045

By:

Zhou, Guangyu;
Fu, Shengyu;
Zhang, Yunsen;
Li, Shuang;
Guo, Ziang;
Ouyang, Defang;
Ying, Tianlei;
Lu, Yinying;
Zhao, Qi

Publication type:

Article

Pluronic F127-modified liposome-containing tacrolimus-cyclodextrin inclusion complexes: improved solubility, cellular uptake and intestinal penetration.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 8, p. 1107, doi. 10.1111/jphp.12074

By:

Zhu, Quanlei;
Guo, Tao;
Xia, Dengning;
Li, Xiuying;
Zhu, Chunliu;
Li, Haiyan;
Ouyang, Defang;
Zhang, Jiwen;
Gan, Yong

Publication type:

Article

Design and evaluation of compound metformin/glipizide elementary osmotic pump tablets.

Published in:

Journal of Pharmacy & Pharmacology, 2005, v. 57, n. 7, p. 817

By:

Defang Ouyang;
Shufang Nie;
Wei Li;
Hong Guo;
Hui Liu;
Weisan Pan

Publication type:

Article

Erythrocyte‐Leveraged Oncolytic Virotherapy (ELeOVt): Oncolytic Virus Assembly on Erythrocyte Surface to Combat Pulmonary Metastasis and Alleviate Side Effects.

Published in:

Advanced Science, 2024, v. 11, n. 5, p. 1, doi. 10.1002/advs.202303907

By:

Liu, Mingyang;
Zhang, Ruizhe;
Huang, Hanwei;
Liu, Pengfei;
Zhao, Xu;
Wu, Hu;
He, Ying;
Xu, Ruizhe;
Qin, Xifeng;
Cheng, Zhenguo;
Liu, Hongyu;
Ergonul, Onder;
Can, Füsun;
Ouyang, Defang;
Wang, Zhenning;
Pang, Zhiqing;
Liu, Funan

Publication type:

Article

Erythrocyte‐Leveraged Oncolytic Virotherapy (ELeOVt): Oncolytic Virus Assembly on Erythrocyte Surface to Combat Pulmonary Metastasis and Alleviate Side Effects (Adv. Sci. 5/2024).

Published in:

Advanced Science, 2024, v. 11, n. 5, p. 1, doi. 10.1002/advs.202470027

By:

Liu, Mingyang;
Zhang, Ruizhe;
Huang, Hanwei;
Liu, Pengfei;
Zhao, Xu;
Wu, Hu;
He, Ying;
Xu, Ruizhe;
Qin, Xifeng;
Cheng, Zhenguo;
Liu, Hongyu;
Ergonul, Onder;
Can, Füsun;
Ouyang, Defang;
Wang, Zhenning;
Pang, Zhiqing;
Liu, Funan

Publication type:

Article

Glutathione Pulse Therapy: Promote Spatiotemporal Delivery of Reduction‐Sensitive Nanoparticles at the "Cellular Level" and Synergize PD‐1 Blockade Therapy.

Published in:

Advanced Science, 2022, v. 9, n. 27, p. 1, doi. 10.1002/advs.202202744

By:

Dong, Songtao;
Zhang, Yuan;
Guo, Xiangnan;
Zhang, Chuang;
Wang, Zhaomeng;
Yu, Jiang;
Liu, Yubo;
Li, Chang;
Hu, Yuting;
Sun, Bingjun;
Sun, Mengchi;
Zhang, Haotian;
Ouyang, Defang;
He, Zhonggui;
Wang, Yongjun

Publication type:

Article

Toward Strong Near‐Infrared Absorption/Emission from Carbon Dots in Aqueous Media through Solvothermal Fusion of Large Conjugated Perylene Derivatives with Post‐Surface Engineering.

Published in:

Advanced Science, 2022, v. 9, n. 23, p. 1, doi. 10.1002/advs.202202283

By:

Liu, Yupeng;
Lei, Josh Haipeng;
Wang, Gang;
Zhang, Zhiming;
Wu, Jun;
Zhang, Bohan;
Zhang, Huiqi;
Liu, Enshan;
Wang, Liming;
Liu, Tzu‐Ming;
Xing, Guichuan;
Ouyang, Defang;
Deng, Chu‐Xia;
Tang, Zikang;
Qu, Songnan

Publication type:

Article