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A Supramolecular Stabilizer of the 14‐3‐3ζ/ERα Protein‐Protein Interaction with a Synergistic Mode of Action.
- Published in:
- Angewandte Chemie, 2020, v. 132, n. 13, p. 5322, doi. 10.1002/ange.201914517
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- Publication type:
- Article
Rationally Designed Semisynthetic Natural Product Analogues for Stabilization of 14‐3‐3 Protein–Protein Interactions.
- Published in:
- Angewandte Chemie, 2018, v. 130, n. 41, p. 13658, doi. 10.1002/ange.201806584
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- Publication type:
- Article
A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3.
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- Angewandte Chemie, 2017, v. 129, n. 31, p. 9126, doi. 10.1002/ange.201701807
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- Publication type:
- Article
Designed Spiroketal Protein Modulation.
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- Angewandte Chemie, 2017, v. 129, n. 20, p. 5572, doi. 10.1002/ange.201612504
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- Publication type:
- Article
Stabilizer-Guided Inhibition of Protein–Protein Interactions.
- Published in:
- Angewandte Chemie, 2015, v. 127, n. 52, p. 15946, doi. 10.1002/ange.201507976
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- Publication type:
- Article
Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4.
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- Chromosome Research, 2011, v. 19, n. 7, p. 883, doi. 10.1007/s10577-011-9244-1
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- Publication type:
- Article
Identification of a Selective, Activity-Based Probe for Glyceraldehyde 3-Phosphate Dehydrogenases.
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- Angewandte Chemie International Edition, 2012, v. 51, n. 21, p. 5230, doi. 10.1002/anie.201107276
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- Publication type:
- Article
Small-Molecule Stabilization of Protein-Protein Interactions: An Underestimated Concept in Drug Discovery?
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- Angewandte Chemie International Edition, 2012, v. 51, n. 9, p. 2012, doi. 10.1002/anie.201107616
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- Publication type:
- Article
Cover Picture: Identification and Structure of Small-Molecule Stabilizers of 14 -3 -3 Protein-Protein Interactions (Angew. Chem. Int. Ed. 24/2010).
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- Angewandte Chemie International Edition, 2010, v. 49, n. 24, p. 3991, doi. 10.1002/anie.201002255
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- Publication type:
- Article
Identification and Structure of Small-Molecule Stabilizers of 14 -3 -3 Protein-Protein Interactions.
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- Angewandte Chemie International Edition, 2010, v. 49, n. 24, p. 4129, doi. 10.1002/anie.200907203
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- Publication type:
- Article
The 14‐3‐3/SLP76 protein–protein interaction in T‐cell receptor signalling: a structural and biophysical characterization.
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- FEBS Letters, 2021, v. 595, n. 3, p. 404, doi. 10.1002/1873-3468.13993
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- Publication type:
- Article
Biophysical and structural insight into the USP8/14‐3‐3 interaction.
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- FEBS Letters, 2018, v. 592, n. 7, p. 1211, doi. 10.1002/1873-3468.13017
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- Publication type:
- Article
Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction.
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- FEBS Letters, 2017, v. 591, n. 16, p. 2449, doi. 10.1002/1873-3468.12723
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- Publication type:
- Article
Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau.
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- FASEB Journal, 2015, v. 29, n. 10, p. 4133, doi. 10.1096/fj.14-265009
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- Publication type:
- Article
Allosteric inhibition of Taspasel's pathobiological activity by enforced dimerization in vivo.
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- FASEB Journal, 2012, v. 26, n. 8, p. 3421, doi. 10.1096/fj.11-202432
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- Publication type:
- Article
Understanding the interaction of 14‐3‐3 proteins with hDMX and hDM2: a structural and biophysical study.
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- FEBS Journal, 2022, v. 289, n. 17, p. 5341, doi. 10.1111/febs.16433
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- Publication type:
- Article
An Optimised Small-Molecule Stabiliser of the 14-3-3-PMA2 Protein-Protein Interaction.
- Published in:
- Chemistry - A European Journal, 2012, v. 18, n. 21, p. 6520, doi. 10.1002/chem.201103761
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- Publication type:
- Article
Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics.
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- Molecules, 2020, v. 25, n. 15, p. 3365, doi. 10.3390/molecules25153365
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- Publication type:
- Article
14-3-3: A Case Study in PPI Modulation.
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- Molecules, 2018, v. 23, n. 6, p. 1386, doi. 10.3390/molecules23061386
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- Publication type:
- Article
Identification of an allosteric binding site for RORγt inhibition.
- Published in:
- Nature Communications, 2015, v. 6, n. 12, p. 8833, doi. 10.1038/ncomms9833
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- Publication type:
- Article
14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban.
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- Science Signaling, 2020, v. 13, n. 647, p. 1, doi. 10.1126/scisignal.aaz1436
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- Publication type:
- Article
14‐3‐3 Protein‐Protein Interactions: From Mechanistic Understanding to Their Small‐Molecule Stabilization.
- Published in:
- ChemBioChem, 2024, v. 25, n. 14, p. 1, doi. 10.1002/cbic.202400214
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- Publication type:
- Article
Discovery of 14‐3‐3 PPI Stabilizers by Extension of an Amidine‐Substituted Thiophene Fragment.
- Published in:
- ChemBioChem, 2024, v. 25, n. 1, p. 1, doi. 10.1002/cbic.202300636
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- Publication type:
- Article
Rationally Designed Semisynthetic Natural Product Analogues for Stabilization of 14‐3‐3 Protein–Protein Interactions.
- Published in:
- Angewandte Chemie International Edition, 2018, v. 57, n. 41, p. 13470, doi. 10.1002/anie.201806584
- By:
- Publication type:
- Article
A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3.
- Published in:
- Angewandte Chemie International Edition, 2017, v. 56, n. 31, p. 8998, doi. 10.1002/anie.201701807
- By:
- Publication type:
- Article
Designed Spiroketal Protein Modulation.
- Published in:
- Angewandte Chemie International Edition, 2017, v. 56, n. 20, p. 5480, doi. 10.1002/anie.201612504
- By:
- Publication type:
- Article
Stabilizer-Guided Inhibition of Protein--Protein Interactions.
- Published in:
- Angewandte Chemie International Edition, 2015, v. 54, n. 52, p. 15629, doi. 10.1002/anie.201507976
- By:
- Publication type:
- Article
A Natural-Product Switch for a Dynamic Protein Interface.
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- Angewandte Chemie International Edition, 2014, v. 53, n. 25, p. 6443, doi. 10.1002/anie.201403773
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- Publication type:
- Article
Constrained Peptides with Target-Adapted Cross-Links as Inhibitors of a Pathogenic Protein-Protein Interaction.
- Published in:
- Angewandte Chemie International Edition, 2014, v. 53, n. 9, p. 2489, doi. 10.1002/anie.201310082
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- Publication type:
- Article
Back Cover: Constrained Peptides with Target-Adapted Cross-Links as Inhibitors of a Pathogenic Protein-Protein Interaction (Angew. Chem. Int. Ed. 9/2014).
- Published in:
- Angewandte Chemie International Edition, 2014, v. 53, n. 9, p. 2510, doi. 10.1002/anie.201400778
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- Publication type:
- Article
Design of Drug‐Like Protein–Protein Interaction Stabilizers Guided By Chelation‐Controlled Bioactive Conformation Stabilization.
- Published in:
- Chemistry - A European Journal, 2020, v. 26, n. 31, p. 7131, doi. 10.1002/chem.202001608
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- Publication type:
- Article
Structural interface between LRRK2 and 14-3-3 protein.
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- Biochemical Journal, 2017, v. 474, n. 7, p. 1273, doi. 10.1042/BCJ20161078
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- Article
Deterministic clustering of the available chemical space.
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- 2013
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- Publication type:
- Conference Paper
From Tethered to Freestanding Stabilizers of 14‐3‐3 Protein‐Protein Interactions through Fragment Linking.
- Published in:
- Angewandte Chemie International Edition, 2023, v. 62, n. 37, p. 1, doi. 10.1002/anie.202308004
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- Publication type:
- Article
Fragment‐Based Stabilizers of Protein–Protein Interactions through Imine‐Based Tethering.
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- Angewandte Chemie International Edition, 2020, v. 59, n. 48, p. 21520, doi. 10.1002/anie.202008585
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- Publication type:
- Article
TEAD–YAP Interaction Inhibitors and MDM2 Binders from DNA‐Encoded Indole‐Focused Ugi Peptidomimetics.
- Published in:
- Angewandte Chemie International Edition, 2020, v. 59, n. 46, p. 20338, doi. 10.1002/anie.202006280
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- Publication type:
- Article
A Supramolecular Stabilizer of the 14‐3‐3ζ/ERα Protein‐Protein Interaction with a Synergistic Mode of Action.
- Published in:
- Angewandte Chemie International Edition, 2020, v. 59, n. 13, p. 5284, doi. 10.1002/anie.201914517
- By:
- Publication type:
- Article
A Natural-Product Switch for a Dynamic Protein Interface.
- Published in:
- Angewandte Chemie, 2014, v. 126, n. 25, p. 6561, doi. 10.1002/ange.201403773
- By:
- Publication type:
- Article
Rücktitelbild: Makrocyclische Peptide mit dem Zielprotein angepassten Kohlenwasserstoffbrücken: Inhibitoren einer pathogenen Protein-Protein-Wechselwirkung (Angew. Chem. 9/2014).
- Published in:
- Angewandte Chemie, 2014, v. 126, n. 9, p. 2544, doi. 10.1002/ange.201400778
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- Publication type:
- Article
Makrocyclische Peptide mit dem Zielprotein angepassten Kohlenwasserstoffbrücken: Inhibitoren einer pathogenen Protein-Protein-Wechselwirkung.
- Published in:
- Angewandte Chemie, 2014, v. 126, n. 9, p. 2522, doi. 10.1002/ange.201310082
- By:
- Publication type:
- Article
Identifizierung einer selektiven aktivitätsbasierten Sonde für Glycerinaldehyd-3-phosphat-Dehydrogenasen.
- Published in:
- Angewandte Chemie, 2012, v. 124, n. 21, p. 5320, doi. 10.1002/ange.201107276
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- Publication type:
- Article
Niedermolekulare Stabilisatoren von Protein-Protein-Wechselwirkungen: ein unterschätztes Konzept in der Wirkstoffentwicklung?
- Published in:
- Angewandte Chemie, 2012, v. 124, n. 9, p. 2052, doi. 10.1002/ange.201107616
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- Publication type:
- Article
Identifizierung und Struktur von niedermolekularen Substanzen als Stabilisatoren von 14 -3 -3-Protein-Protein-Wechselwirkungen.
- Published in:
- Angewandte Chemie, 2010, v. 122, n. 24, p. 4223, doi. 10.1002/ange.200907203
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- Publication type:
- Article
Titelbild: Identifizierung und Struktur von niedermolekularen Substanzen als Stabilisatoren von 14 -3 -3-Protein-Protein-Wechselwirkungen (Angew. Chem. 24/2010).
- Published in:
- Angewandte Chemie, 2010, v. 122, n. 24, p. 4083, doi. 10.1002/ange.201002255
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- Publication type:
- Article
Intermolecular channels direct crystal orientation in mineralized collagen.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18846-2
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- Publication type:
- Article
Subcellular localization of full-length human myeloid leukemia factor 1 (MLF1) is independent of 14-3-3 proteins.
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- Cellular & Molecular Biology Letters, 2013, v. 18, n. 1, p. 137, doi. 10.2478/s11658-012-0044-1
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- Publication type:
- Article
The identification and structural analysis of potential 14‐3‐3 interaction sites on the bone regulator protein Schnurri‐3.
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- Acta Crystallographica: Section F, Structural Biology Communications, 2021, v. 77, n. 8, p. 254, doi. 10.1107/S2053230X21006658
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- Publication type:
- Article
A new soaking procedure for X‐ray crystallographic structural determination of protein–peptide complexes.
- Published in:
- Acta Crystallographica: Section F, Structural Biology Communications, 2020, v. 76, n. 10, p. 501, doi. 10.1107/S2053230X2001122X
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- Publication type:
- Article
Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31206-6
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- Publication type:
- Article
In melanoma, Hippo signaling is affected by copy number alterations and YAP1 overexpression impairs patient survival.
- Published in:
- Pigment Cell & Melanoma Research, 2014, v. 27, n. 4, p. 671, doi. 10.1111/pcmr.12249
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- Publication type:
- Article