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Epigenome-wide association study of DNA methylation in panic disorder.
Published in:
Clinical Epigenetics, 2017, v. 9, p. 1, doi. 10.1186/s13148-016-0307-1
By:
- Mihoko Shimada-Sugimoto;
- Takeshi Otowa;
- Taku Miyagawa;
- Tadashi Umekage;
- Yoshiya Kawamura;
- Miki Bundo;
- Kazuya Iwamoto;
- Mamoru Tochigi;
- Kiyoto Kasai;
- Hisanobu Kaiya;
- Hisashi Tanii;
- Yuji Okazaki;
- Katsushi Tokunaga;
- Tsukasa Sasaki
Publication type:
Article
Six-Year Stability of Affective Temperaments as Measured by TEMPS-A.
Published in:
Psychopathology, 2010, v. 43, n. 4, p. 240, doi. 10.1159/000313522
By:
- Kawamura, Yoshiya;
- Akiyama, Tsuyoshi;
- Shimada, Takafumi;
- Minato, Takanobu;
- Umekage, Tadashi;
- Noda, Yoshihiro;
- Ukawa, Ko;
- Hashidume, Chikara;
- Sakai, Yoshie;
- Otowa, Takeshi;
- Sasaki, Tsukasa;
- Akiskal, Hagop S.
Publication type:
Article
Assessment and characterization of phenotypic heterogeneity of anxiety disorders across five large cohorts.
Published in:
International Journal of Methods in Psychiatric Research, 2016, v. 25, n. 4, p. 255, doi. 10.1002/mpr.1519
By:
- Lee, Minyoung;
- Aggen, Steven H.;
- Otowa, Takeshi;
- Castelao, Enrique;
- Preisig, Martin;
- Grabe, Hans J.;
- Hartman, Catharina A.;
- Oldehinkel, Albertine J.;
- Middeldorp, Christel M.;
- Tiemeier, Henning;
- Hettema, John M.
Publication type:
Article
Parenting and risk for mood, anxiety and substance use disorders: a study in population-based male twins.
Published in:
Social Psychiatry & Psychiatric Epidemiology, 2013, v. 48, n. 11, p. 1841, doi. 10.1007/s00127-013-0656-4
By:
- Otowa, Takeshi;
- Gardner, Charles;
- Kendler, Kenneth;
- Hettema, John
Publication type:
Article
A genome-wide CNV association study on panic disorder in a Japanese population.
Published in:
Journal of Human Genetics, 2011, v. 56, n. 12, p. 852, doi. 10.1038/jhg.2011.117
By:
- Kawamura, Yoshiya;
- Otowa, Takeshi;
- Koike, Asako;
- Sugaya, Nagisa;
- Yoshida, Eiji;
- Yasuda, Shin;
- Inoue, Ken;
- Takei, Kunio;
- Konishi, Yoshiaki;
- Tanii, Hisashi;
- Shimada, Takafumi;
- Tochigi, Mamoru;
- Kakiuchi, Chihiro;
- Umekage, Tadashi;
- Liu, Xiaoxi;
- Nishida, Nao;
- Tokunaga, Katsushi;
- Kuwano, Ryozo;
- Okazaki, Yuji;
- Kaiya, Hisanobu
Publication type:
Article
An association analysis of Per2 with panic disorder in the Japanese population.
Published in:
Journal of Human Genetics, 2011, v. 56, n. 10, p. 748, doi. 10.1038/jhg.2011.94
By:
- Otowa, Takeshi;
- Tochigi, Mamoru;
- Kawamura, Yoshiya;
- Sugaya, Nagisa;
- Yoshida, Eiji;
- Inoue, Ken;
- Yasuda, Shin;
- Umekage, Tadashi;
- Ebisawa, Takashi;
- Tanii, Hisashi;
- Kaiya, Hisanobu;
- Okazaki, Yuji;
- Kato, Nobumasa;
- Sasaki, Tsukasa
Publication type:
Article
An association study between the dymeclin gene and schizophrenia in the Japanese population.
Published in:
Journal of Human Genetics, 2010, v. 55, n. 9, p. 631, doi. 10.1038/jhg.2010.72
By:
- Yazaki, Saori;
- Koga, Minori;
- Ishiguro, Hiroki;
- Inada, Toshiya;
- Ujike, Hiroshi;
- Itokawa, Masanari;
- Otowa, Takeshi;
- Watanabe, Yuichiro;
- Someya, Toshiyuki;
- Iwata, Nakao;
- Kunugi, Hiroshi;
- Ozaki, Norio;
- Arinami, Tadao
Publication type:
Article
Association of the oxytocin receptor (OXTR) gene polymorphisms with autism spectrum disorder (ASD) in the Japanese population.
Published in:
Journal of Human Genetics, 2010, v. 55, n. 3, p. 137, doi. 10.1038/jhg.2009.140
By:
- Xiaoxi Liu;
- Kawamura, Yoshiya;
- Shimada, Takafumi;
- Otowa, Takeshi;
- Koishi, Shinko;
- Sugiyama, Toshiro;
- Nishida, Hisami;
- Hashimoto, Ohiko;
- Nakagami, Ryoichi;
- Tochigi, Mamoru;
- Umekage, Tadashi;
- Kano, Yukiko;
- Miyagawa, Taku;
- Kato, Nobumasa;
- Tokunaga, Katsushi;
- Sasaki, Tsukasa
Publication type:
Article
Replication of a genome-wide association study of panic disorder in a Japanese population.
Published in:
Journal of Human Genetics, 2010, v. 55, n. 2, p. 91, doi. 10.1038/jhg.2009.127
By:
- Otowa, Takeshi;
- Tanii, Hisashi;
- Sugaya, Nagisa;
- Yoshida, Eiji;
- Inoue, Ken;
- Yasuda, Shin;
- Shimada, Takafumi;
- Kawamura, Yoshiya;
- Tochigi, Mamoru;
- Minato, Takanobu;
- Umekage, Tadashi;
- Miyagawa, Taku;
- Nishida, Nao;
- Tokunaga, Katsushi;
- Okazaki, Yuji;
- Kaiya, Hisanobu;
- Sasaki, Tsukasa
Publication type:
Article
No association between the brain-derived neurotrophic factor gene and panic disorder in Japanese population.
Published in:
Journal of Human Genetics, 2009, v. 54, n. 8, p. 437, doi. 10.1038/jhg.2009.46
By:
- Otowa, Takeshi;
- Shimada, Takafumi;
- Kawamura, Yoshiya;
- Xiaoxi Liu;
- Inoue, Ken;
- Sugaya, Nagisa;
- Minato, Takanobu;
- Nakagami, Ryoichi;
- Tochigi, Mamoru;
- Umekage, Tadashi;
- Kasai, Kiyoto;
- Kato, Nobumasa;
- Tanii, Hisashi;
- Okazaki, Yuji;
- Kaiya, Hisanobu;
- Sasaki, Tsukasa
Publication type:
Article
A two-stage case–control association study of PADI2 with schizophrenia.
Published in:
Journal of Human Genetics, 2009, v. 54, n. 7, p. 430, doi. 10.1038/jhg.2009.52
By:
- Watanabe, Yuichiro;
- Nunokawa, Ayako;
- Kaneko, Naoshi;
- Arinami, Tadao;
- Ujike, Hiroshi;
- Inada, Toshiya;
- Iwata, Nakao;
- Kunugi, Hiroshi;
- Itokawa, Masanari;
- Otowa, Takeshi;
- Ozaki, Norio;
- Someya, Toshiyuki
Publication type:
Article
Genome-wide association study of panic disorder in the Japanese population.
Published in:
Journal of Human Genetics, 2009, v. 54, n. 2, p. 122, doi. 10.1038/jhg.2008.17
By:
- Otowa, Takeshi;
- Yoshida, Eiji;
- Sugaya, Nagisa;
- Yasuda, Shin;
- Nishimura, Yukika;
- Inoue, Ken;
- Tochigi, Mamoru;
- Umekage, Tadashi;
- Miyagawa, Taku;
- Nishida, Nao;
- Tokunaga, Katsushi;
- Tanii, Hisashi;
- Sasaki, Tsukasa;
- Kaiya, Hisanobu;
- Okazaki, Yuji
Publication type:
Article
Two-stage case–control association study of polymorphisms in rheumatoid arthritis susceptibility genes with schizophrenia.
Published in:
Journal of Human Genetics, 2009, v. 54, n. 1, p. 62, doi. 10.1038/jhg.2008.4
By:
- Watanabe, Yuichiro;
- Nunokawa, Ayako;
- Kaneko, Naoshi;
- Muratake, Tatsuyuki;
- Arinami, Tadao;
- Ujike, Hiroshi;
- Inada, Toshiya;
- Iwata, Nakao;
- Kunugi, Hiroshi;
- Itokawa, Masanari;
- Otowa, Takeshi;
- Ozaki, Norio;
- Someya, Toshiyuki
Publication type:
Article
Appropriate data cleaning methods for genome-wide association study.
Published in:
Journal of Human Genetics, 2008, v. 53, n. 10, p. 886, doi. 10.1007/s10038-008-0322-y
By:
- Miyagawa, Taku;
- Nishida, Nao;
- Ohashi, Jun;
- Kimura, Ryosuke;
- Fujimoto, Akihiro;
- Kawashima, Minae;
- Koike, Asako;
- Sasaki, Tsukasa;
- Tanii, Hisashi;
- Otowa, Takeshi;
- Momose, Yoshio;
- Nakahara, Yasuo;
- Gotoh, Jun;
- Okazaki, Yuji;
- Tsuji, Shoji;
- Tokunaga, Katsushi
Publication type:
Article
Anger tendency may be associated with duration of illness in panic disorder.
Published in:
BioPsychoSocial Medicine, 2015, v. 9, n. 1, p. 1, doi. 10.1186/s13030-015-0035-3
By:
- Nagisa Sugaya;
- Eiji Yoshida;
- Shin Yasuda;
- Mamoru Tochigi;
- Kunio Takei;
- Takeshi Otowa;
- Tadashi Umekage;
- Yoshiaki Konishi;
- Yuji Sakano;
- Shinobu Nomura;
- Yuji Okazaki;
- Hisanobu Kaiya;
- Hisashi Tanii;
- Tsukasa Sasaki
Publication type:
Article
Oxytocin receptor gene variations predict neural and behavioral response to oxytocin in autism.
Published in:
Social Cognitive & Affective Neuroscience, 2017, v. 12, n. 3, p. 496, doi. 10.1093/scan/nsw150
By:
- Takamitsu Watanabe;
- Takeshi Otowa;
- Osamu Abe;
- Hitoshi Kuwabara;
- Yuta Aoki;
- Tatsunobu Natsubori;
- Hidemasa Takao;
- Chihiro Kakiuchi;
- Kenji Kondo;
- Masashi Ikeda;
- Nakao Iwata;
- Kiyoto Kasai;
- Tsukasa Sasaki;
- Hidenori Yamasue
Publication type:
Article
Genome-wide Association Study of Autism Spectrum Disorder in the East Asian Populations.
Published in:
Autism Research: Official Journal of the International Society for Autism Research, 2016, v. 9, n. 3, p. 340, doi. 10.1002/aur.1536
By:
- Liu, Xiaoxi;
- Shimada, Takafumi;
- Otowa, Takeshi;
- Wu, Yu‐Yu;
- Kawamura, Yoshiya;
- Tochigi, Mamoru;
- Iwata, Yasuhide;
- Umekage, Tadashi;
- Toyota, Tomoko;
- Maekawa, Motoko;
- Iwayama, Yoshimi;
- Suzuki, Katsuaki;
- Kakiuchi, Chihiro;
- Kuwabara, Hitoshi;
- Kano, Yukiko;
- Nishida, Hisami;
- Sugiyama, Toshiro;
- Kato, Nobumasa;
- Chen, Chia‐Hsiang;
- Mori, Norio
Publication type:
Article
Genome-Wide and Gene-Based Association Studies of Anxiety Disorders in European and African American Samples.
Published in:
PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0112559
By:
- Otowa, Takeshi;
- Maher, Brion S.;
- Aggen, Steven H.;
- McClay, Joseph L.;
- van den Oord, Edwin J.;
- Hettema, John M.
Publication type:
Article
Whole-exome sequencing and gene-based rare variant association tests suggest that PLA2G4E might be a risk gene for panic disorder.
Published in:
Translational Psychiatry, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41398-017-0088-0
By:
- Morimoto, Yoshiro;
- Shimada-Sugimoto, Mihoko;
- Otowa, Takeshi;
- Yoshida, Shintaro;
- Kinoshita, Akira;
- Mishima, Hiroyuki;
- Yamaguchi, Naohiro;
- Mori, Takatoshi;
- Imamura, Akira;
- Ozawa, Hiroki;
- Kurotaki, Naohiro;
- Ziegler, Christiane;
- Domschke, Katharina;
- Deckert, Jürgen;
- Umekage, Tadashi;
- Tochigi, Mamoru;
- Kaiya, Hisanobu;
- Okazaki, Yuji;
- Tokunaga, Katsushi;
- Sasaki, Tsukasa
Publication type:
Article
Shared trans‐ancestry genetic etiology between panic disorder and anxiety disorders.
Published in:
Psychiatry & Clinical Neurosciences, 2021, v. 75, n. 6, p. 209, doi. 10.1111/pcn.13214
By:
- Ohi, Kazutaka;
- Otowa, Takeshi;
- Shimada, Mihoko;
- Sugiyama, Shunsuke;
- Tanahashi, Shunsuke;
- Kaiya, Hisanobu;
- Nishimura, Fumichika;
- Sasaki, Tsukasa;
- Tanii, Hisashi;
- Shioiri, Toshiki
Publication type:
Article
Does cognitive behavioral therapy for anxiety disorders assist the discontinuation of benzodiazepines among patients with anxiety disorders? A systematic review and meta‐analysis.
Published in:
Psychiatry & Clinical Neurosciences, 2021, v. 75, n. 4, p. 119, doi. 10.1111/pcn.13195
By:
- Takeshima, Masahiro;
- Otsubo, Tempei;
- Funada, Daisuke;
- Murakami, Maki;
- Usami, Takashi;
- Maeda, Yoshihiro;
- Yamamoto, Taisuke;
- Matsumoto, Toshihiko;
- Shimane, Takuya;
- Aoki, Yumi;
- Otowa, Takeshi;
- Tani, Masayuki;
- Yamanaka, Gaku;
- Sakai, Yojiro;
- Murao, Tomohiko;
- Inada, Ken;
- Yamada, Hiroki;
- Kikuchi, Toshiaki;
- Sasaki, Tsukasa;
- Watanabe, Norio
Publication type:
Article
Genetics of anxiety disorders: Genetic epidemiological and molecular studies in humans.
Published in:
Psychiatry & Clinical Neurosciences, 2015, v. 69, n. 7, p. 388, doi. 10.1111/pcn.12291
By:
- Shimada‐Sugimoto, Mihoko;
- Otowa, Takeshi;
- Hettema, John M.
Publication type:
Article
Irritable bowel syndrome, its cognition, anxiety sensitivity, and anticipatory anxiety in panic disorder patients.
Published in:
Psychiatry & Clinical Neurosciences, 2013, v. 67, n. 6, p. 397, doi. 10.1111/pcn.12069
By:
- Sugaya, Nagisa;
- Yoshida, Eiji;
- Yasuda, Shin;
- Tochigi, Mamoru;
- Takei, Kunio;
- Ohtani, Toshiyuki;
- Otowa, Takeshi;
- Minato, Takanobu;
- Umekage, Tadashi;
- Sakano, Yuji;
- Chen, Junwen;
- Shimada, Hironori;
- Nomura, Shinobu;
- Okazaki, Yuji;
- Kaiya, Hisanobu;
- Tanii, Hisashi;
- Sasaki, Tsukasa
Publication type:
Article
No association between CLOCK gene 3111C/T polymorphism and personality traits in healthy Japanese subjects.
Published in:
Psychiatry & Clinical Neurosciences, 2011, v. 65, n. 6, p. 604, doi. 10.1111/j.1440-1819.2011.02259.x
By:
- Otowa, Takeshi;
- Tochigi, Mamoru;
- Umekage, Tadashi;
- Ebisawa, Takashi;
- Kasai, Kiyoto;
- Kato, Nobumasa;
- Sasaki, Tsukasa
Publication type:
Article
Association between corticotropin-releasing hormone receptor 2 ( CRHR2) gene polymorphism and personality traits.
Published in:
Psychiatry & Clinical Neurosciences, 2006, v. 60, n. 4, p. 524, doi. 10.1111/j.1440-1819.2006.01541.x
By:
- TOCHIGI, MAMORU;
- KATO, CHIEKO;
- OTOWA, TAKESHI;
- HIBINO, HIROYUKI;
- MARUI, TETSUYA;
- OHTANI, TOSHIYUKI;
- UMEKAGE, TADASHI;
- KATO, NOBUMASA;
- SASAKI, TSUKASA
Publication type:
Article
The First Pilot Genome-Wide Gene-Environment Study of Depression in the Japanese Population.
Published in:
PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0160823
By:
- Otowa, Takeshi;
- Kawamura, Yoshiya;
- Tsutsumi, Akizumi;
- Kawakami, Norito;
- Kan, Chiemi;
- Shimada, Takafumi;
- Umekage, Tadashi;
- Kasai, Kiyoto;
- Tokunaga, Katsushi;
- Sasaki, Tsukasa
Publication type:
Article
Sensitivity to gene dosage and gene expression affects genes with copy number variants observed among neuropsychiatric diseases.
Published in:
BMC Medical Genomics, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s12920-020-0699-9
By:
- Yamasaki, Maria;
- Makino, Takashi;
- Khor, Seik-Soon;
- Toyoda, Hiromi;
- Miyagawa, Taku;
- Liu, Xiaoxi;
- Kuwabara, Hitoshi;
- Kano, Yukiko;
- Shimada, Takafumi;
- Sugiyama, Toshiro;
- Nishida, Hisami;
- Sugaya, Nagisa;
- Tochigi, Mamoru;
- Otowa, Takeshi;
- Okazaki, Yuji;
- Kaiya, Hisanobu;
- Kawamura, Yoshiya;
- Miyashita, Akinori;
- Kuwano, Ryozo;
- Kasai, Kiyoto
Publication type:
Article
Association of Serotonin Transporter Gene (5-HTTLPR/rs25531) Polymorphism with Comorbidities of Panic Disorder.
Published in:
Neuropsychobiology, 2021, v. 80, n. 4, p. 333, doi. 10.1159/000512699
By:
- Tanahashi, Shunsuke;
- Tanii, Hisashi;
- Konishi, Yoshiaki;
- Otowa, Takeshi;
- Sasaki, Tsukasa;
- Tochigi, Mamoru;
- Okazaki, Yuji;
- Kaiya, Hisanobu;
- Okada, Motohiro
Publication type:
Article
Gender-Specific Association between the COMT Val158Met Polymorphism and Openness to Experience in Panic Disorder Patients.
Published in:
Neuropsychobiology, 2014, v. 69, n. 3, p. 165, doi. 10.1159/000360737
By:
- Konishi, Yoshiaki;
- Tanii, Hisashi;
- Otowa, Takeshi;
- Sasaki, Tsukasa;
- Motomura, Eishi;
- Fujita, asuna;
- Umekage, Tadashi;
- Tochigi, Mamoru;
- Kaiya, Hisanobu;
- Okazaki, Yuji;
- Okada, Motohiro
Publication type:
Article
Discrimination between healthy participants and people with panic disorder based on polygenic scores for psychiatric disorders and for intermediate phenotypes using machine learning.
Published in:
Australian & New Zealand Journal of Psychiatry, 2024, v. 58, n. 7, p. 603, doi. 10.1177/00048674241242936
By:
- Ohi, Kazutaka;
- Tanaka, Yuta;
- Otowa, Takeshi;
- Shimada, Mihoko;
- Kaiya, Hisanobu;
- Nishimura, Fumichika;
- Sasaki, Tsukasa;
- Tanii, Hisashi;
- Shioiri, Toshiki;
- Hara, Takeshi
Publication type:
Article
Association between oxytocin receptor gene polymorphisms and autistic traits as measured by the Autism- Spectrum Quotient in a non-clinical Japanese population.
Published in:
Asia-Pacific Psychiatry, 2011, v. 3, n. 3, p. 128, doi. 10.1111/j.1758-5872.2011.00132.x
By:
- Kawamura, Yoshiya;
- Liu, Xiaoxi;
- Shimada, Takafumi;
- Otowa, Takeshi;
- Kakiuchi, Chihiro;
- Akiyama, Tsuyoshi;
- Umekage, Tadashi;
- Sasaki, Tsukasa
Publication type:
Article
No association of DRD2, DRD3, and tyrosine hydroxylase gene polymorphisms with personality traits in the Japanese population.
Published in:
Behavioral & Brain Functions, 2006, v. 2, p. 32, doi. 10.1186/1744-9081-2-32
By:
- Hibino, Hiroyuki;
- Tochigi, Mamoru;
- Otowa, Takeshi;
- Kato, Nobumasa;
- Sasaki, Tsukasa
Publication type:
Article

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