Works by Otonkoski T

Results: 33

Congenital hyperinsulinism, neonatal diabetes and the risk of malignancies: an international collaborative study. Preliminary communication.
Published in:
Diabetic Medicine, 2015, v. 32, n. 5, p. 701, doi. 10.1111/dme.12670
By:
- Makov, M.;
- Chodick, G.;
- Mohnike, K.;
- Otonkoski, T.;
- Huopio, H.;
- Banerjee, I.;
- Cave, H.;
- Polak, M.;
- Christesen, H. T.;
- Hussain, K.;
- Deleon, D.;
- Stanley, C.;
- Cappa, M.;
- Ramos, O.;
- Zangen, D.;
- Laron, Z.
Publication type:
Article
Acute Insulin Response Tests for the Differential Diagnosis of Congenital Hyperinsulinism.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2002, v. 87, n. 10, p. 4502, doi. 10.1210/jc.2002-020378
By:
- HUOPIO, H.;
- JÄÄSKELÄINEN, J.;
- KOMULAINEN, J.;
- MIETTINEN, R.;
- KÄRKKÄINEN, P.;
- LAAKSO, M.;
- TAPANAINEN, P.;
- VOUTILAINEN, R.;
- OTONKOSKI, T.
Publication type:
Article
Blood vessels of human islets of Langerhans are surrounded by a double basement membrane.
Published in:
Diabetologia, 2008, v. 51, n. 7, p. 1181, doi. 10.1007/s00125-008-0997-9
By:
- Virtanen, I.;
- Banerjee, M.;
- Palgi, J.;
- Korsgren, O.;
- Lukinius, A.;
- Thornell, L.-E.;
- Kikkawa, Y.;
- Sekiguchi, K.;
- Hukkanen, M.;
- Konttinen, Y.;
- Otonkoski, T.
Publication type:
Article
In vitro neogenesis of human islets reflects the plasticity of differentiated human pancreatic cells.
Published in:
Diabetologia, 2005, v. 48, n. 11, p. 2296, doi. 10.1007/s00125-005-1935-8
By:
- Gao, R.;
- Ustinov, J.;
- Korsgren, O.;
- Otonkoski, T.
Publication type:
Article
Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets.
Published in:
Diabetologia, 2005, v. 48, n. 8, p. 1510, doi. 10.1007/s00125-005-1839-7
By:
- Ylipaasto, P.;
- Kutlu, B.;
- Rasilainen, S.;
- Rasschaert, J.;
- Salmela, K.;
- Teerijoki, H.;
- Korsgren, O.;
- Lahesmaa, R.;
- Hovi, T.;
- Eizirik, D. L.;
- Otonkoski, T.;
- Roivainen, M.
Publication type:
Article
Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells P. Ylipaasto et al.: Islet tropism and receptor usage of enteroviruses.
Published in:
Diabetologia, 2004, v. 47, n. 2, p. 225, doi. 10.1007/s00125-003-1297-z
By:
- Ylipaasto, P.;
- Klingel, K.;
- Lindberg, A. M.;
- Otonkoski, T.;
- Kandolf, R.;
- Hovi, T.;
- Roivainen, M.
Publication type:
Article
Characterisation of new K<sub>ATP</sub>-channel mutations associated with congenital hyperinsulinism in the Finnish population.
Published in:
2004
By:
- Reimann, F.;
- Huopio, H.;
- Dabrowski, M.;
- Proks, P.;
- Gribble, F. M.;
- Laakso, M.;
- Otonkoski, T.;
- Ashcroft, F. M.
Publication type:
Erratum
Characterisation of new K<sub>ATP</sub>-channel mutations associated with congenital hyperinsulinism in the Finnish population F. Reimann et al.: KATP-channel mutations causing CHI.
Published in:
Diabetologia, 2003, v. 46, n. 2, p. 241, doi. 10.1007/s00125-002-1014-3
By:
- Reimann, F.;
- Huopio, H.;
- Dabrowski, M.;
- Proks, P.;
- Gribble, F. M.;
- Laakso, M.;
- Otonkoski, T.;
- Ashcroft, F. M.
Publication type:
Article
Functional impairment and killing of human beta cells by enteroviruses: the capacity is shared by a wide range of serotypes, but the extent is a characteristic of individual virus strains M. Roivainen et al.: Enterovirus infection in human pancreatic beta-cells
Published in:
Diabetologia, 2002, v. 45, n. 5, p. 693, doi. 10.1007/s00125-002-0805-x
By:
- Roivainen, M.;
- Ylipaasto, P.;
- Savolainen, C.;
- Galama, J.;
- Hovi, T.;
- Otonkoski, T.
Publication type:
Article
Nephrin is expressed in the pancreatic beta cells.
Published in:
Diabetologia, 2001, v. 44, n. 10, p. 1274
By:
- Palmén, T.;
- Ahola, H.;
- Palgi, J.;
- Aaltonen, P.;
- Luimula, P.;
- Wang, S.;
- Jaakkola, I.;
- Knip, M.;
- Otonkoski, T.;
- Holthöfer, H.
Publication type:
Article
Neonatal Type I diabetes associated with maternal echovirus 6 infection: a case report.
Published in:
Diabetologia, 2000, v. 43, n. 10, p. 1235, doi. 10.1007/s001250051518
By:
- Otonkoski, T.;
- Roivainen, M.;
- Vaarala, O.;
- Dinesen, B.;
- Leipälä, J. A.;
- Hovi, T.;
- Knip, M.
Publication type:
Article
Unique basement membrane structure of human pancreatic islets: implications for β-cell growth and differentiation.
Published in:
Diabetes, Obesity & Metabolism, 2008, v. 10, p. 119, doi. 10.1111/j.1463-1326.2008.00955.x
By:
- Otonkoski, T.;
- Banerjee, M.;
- Korsgren, O.;
- Thornell, L.-E.;
- Virtanen, I.
Publication type:
Article
Dedifferentiation for replication of human beta-cells: a division between mice and men?
Published in:
2008
By:
- Billestrup N;
- Otonkoski T
Publication type:
Journal Article
Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth.
Published in:
2006
By:
- Miettinen PJ;
- Ustinov J;
- Ormio P;
- Gao R;
- Palgi J;
- Hakonen E;
- Juntti-Berggren L;
- Berggren P;
- Otonkoski T
Publication type:
Journal Article
Noninvasive diagnosis of focal hyperinsulinism of infancy with [18F]-DOPA positron emission tomography.
Published in:
2006
By:
- Otonkoski T;
- Näntö-Salonen K;
- Seppänen M;
- Veijola R;
- Huopio H;
- Hussain K;
- Tapanainen P;
- Eskola O;
- Parkkola R;
- Ekström K;
- Guiot Y;
- Rahier J;
- Laakso M;
- Rintala R;
- Nuutila P;
- Minn H
Publication type:
Journal Article
Stimulated endocrine cell proliferation and differentiation in transplanted human pancreatic islets: effects of the ob gene and compensatory growth of the implantation organ.
Published in:
2001
By:
- Tyrberg, Björn;
- Ustinov, Jarkko;
- Otonkoski, Timo;
- Andersson, Arne;
- Tyrberg, B;
- Ustinov, J;
- Otonkoski, T;
- Andersson, A
Publication type:
journal article
A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland.
Published in:
1999
By:
- Otonkoski, Timo;
- Ammala, Carina;
- Huopio, Hanna;
- Cote, Gilbert J.;
- Chapman, Joanna;
- Cosgrove, Karen;
- Ashfield, Rebecca;
- Huang, Eileen;
- Komulainen, Jorma;
- Ashcroft, Frances M.;
- Dunne, Mark J.;
- Kere, Juha;
- Thomas, Pamela M.;
- Otonkoski, T;
- Ammälä, C;
- Huopio, H;
- Cote, G J;
- Chapman, J;
- Cosgrove, K;
- Ashfield, R
Publication type:
journal article
Culture of adult human islet preparations with hepatocyte growth factor and 804G matrix is mitogenic for duct cells but not for beta-cells.
Published in:
1998
By:
- Lefebvre, Veronique H.;
- Otonkoski, Timo;
- Ustinov, Jarkko;
- Huotori, Mari-Anne;
- Pipeleers, Daniel G.;
- Bouwens, Luc;
- Lefebvre, V H;
- Otonkoski, T;
- Ustinov, J;
- Huotari, M A;
- Pipeleers, D G;
- Bouwens, L
Publication type:
journal article
Functional beta-cell mass after transplantation of human fetal pancreatic cells: differentiation or proliferation?
Published in:
1997
By:
- Beattie, G M;
- Otonkoski, T;
- Lopez, A D;
- Hayek, A
Publication type:
journal article
Regulation of proliferation and differentiation of human fetal pancreatic islet cells by extracellular matrix, hepatocyte growth factor, and cell-cell contact.
Published in:
1996
By:
- Beattie, Gillian M.;
- Rubin, Jeffrey S.;
- Mally, Martin I.;
- Otonkoski, Timo;
- Hayek, Alberto;
- Beattie, G M;
- Rubin, J S;
- Mally, M I;
- Otonkoski, T;
- Hayek, A
Publication type:
journal article
Ontogeny and tissue distribution of human GAD expression.
Published in:
1996
By:
- Mally, M I;
- Cirulli, V;
- Otonkoski, T;
- Soto, G;
- Hayek, A
Publication type:
journal article
Opposite effects of beta-cell differentiation and growth on reg expression in human fetal pancreatic cells.
Published in:
1994
By:
- Otonkoski, T;
- Mally, M I;
- Hayek, A
Publication type:
journal article
Hepatocyte growth factor/scatter factor has insulinotropic activity in human fetal pancreatic cells.
Published in:
1994
By:
- Otonkoski, Timo;
- Beattie, Gillian M.;
- Rubin, Jeffrey S.;
- Lopez, Ana D.;
- Baird, Andrew;
- Hayek, Alberto;
- Otonkoski, T;
- Beattie, G M;
- Rubin, J S;
- Lopez, A D;
- Baird, A;
- Hayek, A
Publication type:
journal article
Effects of growth hormone and insulin-like growth factor I on endocrine function of human fetal islet-like cell clusters during long-term tissue culture.
Published in:
1988
By:
- Otonkoski, Timo;
- Knip, Mikael;
- Wong, IniéS;
- Simell, Olli;
- Otonkoski, T;
- Knip, M;
- Wong, I;
- Simell, O
Publication type:
journal article
Severe Transient Neonatal Hyperinsulinism Associated with Hyperlactataemia in Non-asphyxiated Infants.
Published in:
Journal of Pediatric Endocrinology & Metabolism, 2004, v. 17, n. 2, p. 203, doi. 10.1515/jpem.2004.17.2.203
By:
- Hussain, K.;
- Thornton, P. S.;
- Otonkoski, T.;
- Aynsley-Green, A.
Publication type:
Article
cDNA cloning, expression studies and chromosome mapping of human type I serine/threonine kinase receptor ALK7 (ACVR1C).
Published in:
Cytogenetics & Cell Genetics, 2001, v. 95, n. 3/4, p. 157, doi. 10.1159/000059339
By:
- Bondestam, J.;
- Huotari, M. -A.;
- Morén, A.;
- Ustinov, J.;
- Kaivo-oja, N.;
- Kallio, J.;
- Horelli-Kuitunen, N.;
- Aaltonen, J.;
- Fujii, M.;
- Moustakas, A.;
- ten Dijke, P.;
- Otonkoski, T.;
- Ritvos, O.
Publication type:
Article
Maturation of insulin response to glucose during human fetal and neonatal development. Studies with perifusion of pancreatic isletlike cell clusters.
Published in:
1988
By:
- Otonkoski, Timo;
- Andersson, Sture;
- Knip, Mikael;
- Simell, Olli;
- Otonkoski, T;
- Andersson, S;
- Knip, M;
- Simell, O
Publication type:
journal article
Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders.
Published in:
BMC Medicine, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12916-022-02699-1
By:
- Auvinen, P.;
- Vehviläinen, J.;
- Marjonen, H.;
- Modhukur, V.;
- Sokka, J.;
- Wallén, E.;
- Rämö, K.;
- Ahola, L.;
- Salumets, A.;
- Otonkoski, T.;
- Skottman, H.;
- Ollikainen, M.;
- Trokovic, R.;
- Kahila, H.;
- Kaminen-Ahola, N.
Publication type:
Article
Prevalence and characteristics of diabetes among Somali children and adolescents living in Helsinki, Finland.
Published in:
Pediatric Diabetes, 2012, v. 13, n. 2, p. 176, doi. 10.1111/j.1399-5448.2011.00783.x
By:
- Oilinki, T;
- Otonkoski, T;
- Ilonen, J;
- Knip, M;
- Miettinen, PJ
Publication type:
Article
Molecular analysis of novel PROP1 mutations associated with combined pituitary hormone deficiency (CPHD).
Published in:
Clinical Endocrinology, 2009, v. 70, n. 1, p. 96, doi. 10.1111/j.1365-2265.2008.03326.x
By:
- Kelberman, D.;
- Turton, J. P. G.;
- Woods, K. S.;
- Mehta, A.;
- Al-Khawari, M.;
- Greening, J.;
- Swift, P. G. F.;
- Otonkoski, T.;
- Rhodes, S. J.;
- Dattani, M. T.
Publication type:
Article
Association of exercise-induced hyperinsulinaemic hypoglycaemia with MCT1-expressing insulinoma.
Published in:
Diabetologia, 2013, v. 56, n. 1, p. 31, doi. 10.1007/s00125-012-2750-7
By:
- Marquard, J.;
- Welters, A.;
- Buschmann, T.;
- Barthlen, W.;
- Vogelgesang, S.;
- Klee, D.;
- Krausch, M.;
- Raffel, A.;
- Otter, S.;
- Piemonti, L.;
- Mayatepek, E.;
- Otonkoski, T.;
- Lammert, E.;
- Meissner, T.
Publication type:
Article
Epidermal growth factor (EGF)-receptor signalling is needed for murine beta cell mass expansion in response to high-fat diet and pregnancy but not after pancreatic duct ligation.
Published in:
Diabetologia, 2011, v. 54, n. 7, p. 1735, doi. 10.1007/s00125-011-2153-1
By:
- Hakonen, E.;
- Ustinov, J.;
- Mathijs, I.;
- Palgi, J.;
- Bouwens, L.;
- Miettinen, P.;
- Otonkoski, T.
Publication type:
Article
A simple two-step protocol for the purification of human pancreatic beta cells.
Published in:
Diabetologia, 2009, v. 52, n. 4, p. 621, doi. 10.1007/s00125-009-1259-1
By:
- Banerjee, M.;
- Otonkoski, T.
Publication type:
Article