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Minimal residual disease detection defined as the malignant fraction of the total primitive stem cell compartment offers additional prognostic information in acute myeloid leukaemia.
Published in:
International Journal of Laboratory Hematology, 2012, v. 34, n. 4, p. 432, doi. 10.1111/j.1751-553X.2012.01416.x
By:
- TERWIJN, M.;
- KELDER, A.;
- SNEL, A. N.;
- RUTTEN, A. P.;
- SCHOLTEN, W. J.;
- OUSSOREN, Y. J. M.;
- Van De LOOSDRECHT, A. A.;
- ZWEEGMAN, S.;
- OSSENKOPPELE, G. J.;
- SCHUURHUIS, G. J.
Publication type:
Article
Storage of unprocessed G-CSF-mobilized whole blood in a modified Leibovitz’s L15 medium preserves clonogenic capacity for at least 7 days.
Published in:
Bone Marrow Transplantation, 2001, v. 28, n. 2, p. 145, doi. 10.1038/sj.bmt.1703127
By:
- de Kreuk, A M;
- Jonkhoff, A R;
- Zevenbergen, A;
- Hendriks, E C M;
- Schuurhuis, G J;
- Ossenkoppele, G J;
- Dräger, A M;
- van Oostveen, J W;
- Huijgens, P C
Publication type:
Article
High-dose melphalan with G-CSF-stimulated whole blood rescue followed by stem cell harvesting and busulphan/cyclophosphamide with autologous stem cell transplantation in multiple myeloma.
Published in:
Bone Marrow Transplantation, 2001, v. 27, n. 9, p. 925, doi. 10.1038/sj.bmt.1703013
By:
- Huijgens, P C;
- Dekker-van Roessel, H M;
- Jonkhoff, A R;
- Admiraal, G C;
- Zweegman, S;
- Schuurhuis, G J;
- Ossenkoppele, G J
Publication type:
Article
Large populations of non-clonogenic early apoptotic CD34-positive cells are present in frozen-thawed peripheral blood stem cell transplants.
Published in:
Bone Marrow Transplantation, 2001, v. 27, n. 5, p. 487, doi. 10.1038/sj.bmt.1702809
By:
- Schuurhuis, G J;
- Muijen, M Monnee-v;
- Oberink, J W;
- de Boer, F;
- Ossenkoppele, G J;
- Broxterman, H J
Publication type:
Article
Mobilisation of haemopoietic progenitors in CML: a second course of intensive chemotherapy does not improve Ph-negativity in stem cell harvests.
Published in:
Bone Marrow Transplantation, 2000, v. 25, n. 11, p. 1147, doi. 10.1038/sj.bmt.1702420
By:
- Janssen, J J W M;
- van Rijn, R S;
- van der Holt, B;
- Schuurhuis, G-J;
- Vellenga, E;
- Verhoef, G E G;
- Ossenkoppele, G J;
- van den Berg, E;
- Hagemeijer, A;
- Släter, R;
- Nieuwint, A W M;
- Cornelissen, J J
Publication type:
Article
Mobilization of hematopoietic progenitors in patients with chronic myeloid leukemia.
Published in:
Bone Marrow Transplantation, 1997, v. 20, n. 10, p. 835, doi. 10.1038/sj.bmt.1700991
By:
- Thijsen, S F T;
- Schuurhuis, G J;
- van Oostveen, J W;
- Theijsmeijer, A P;
- Niewint, A W M;
- Ossenkoppele, G J
Publication type:
Article
Radiotherapy versus radiotherapy plus chemotherapy in stages I and II non-Hodgkin's lymphoma of the upper digestive and respiratory tract.
Published in:
1987
By:
- Ossenkoppele, Gerrit J.;
- Mol, Jaap J.;
- Snow, Gordon B.;
- Karim, Abul B. M. F.;
- Veldhuijzen, Roel W.;
- Nauta, Josef P.;
- Langenhuijsen, Mart M. A. C.;
- Ossenkoppele, G J;
- Mol, J J;
- Snow, G B;
- Karim, A B;
- Veldhuijzen, R W;
- Nauta, J P;
- Langenhuijsen, M M
Publication type:
journal article
Functional characterization of minimal residual disease for P-glycoprotein and multidrug resistance protein activity in acute myeloid leukemia.
Published in:
2001
By:
- van der Pol, M A;
- Pater, J M;
- Feller, N;
- Westra, A H;
- van Stijn, A;
- Ossenkoppele, G J;
- Broxterman, H J;
- Schuurhuis, G J
Publication type:
journal article
Percentage of activated cytotoxic T-lymphocytes in anaplastic large cell lymphoma and Hodgkin's disease: an independent biological prognostic marker.
Published in:
2001
By:
- ten Berge, R L;
- Oudejans, J J;
- Dukers, D F;
- Meijer, J W R;
- Ossenkoppele, G J;
- Meijer, C J L M;
- Meijer, J W;
- Meijer, C J
Publication type:
journal article
P-glycoprotein in primary acute myeloid leukemia and treatment outcome of idarubicin/cytosine arabinoside-based induction therapy.
Published in:
2000
By:
- Broxterman, H J;
- Sonneveld, P;
- van Putten, W J L;
- Lankelma, J;
- Eekman, C A;
- Ossenkoppele, G J;
- Pinedo, H M;
- Löwenberg, B;
- Schuurhuis, G J;
- van Putten, W J
Publication type:
journal article
Chronic myeloid leukemia from basics to bedside.
Published in:
1999
By:
- Thijsen, S F T;
- Schuurhuis, G J;
- van Oostveen, J W;
- Ossenkoppele, G J;
- Thijsen, S;
- Schuurhuis, G;
- van Oostveen, J;
- Ossenkoppele, G
Publication type:
journal article
A randomized study of granulocyte colony-stimulating factor applied during and after chemotherapy in patients with poor risk myelodysplastic syndromes: a report from the HOVON Cooperative Group. Dutch-Belgian Hemato-Oncology Cooperative Group.
Published in:
1999
By:
- Ossenkoppele, G J;
- van der Holt, B;
- Verhoef, G E G;
- Daenen, S M G J;
- Verdonck, L F;
- Sonneveld, P;
- Wijermans, P W;
- van der Lelie, J;
- van Putten, W L J;
- Löwenberg, B;
- Verhoef, G E;
- Daenen, S M;
- van Putten, W L
Publication type:
journal article
Do P-glycoprotein and major vault protein (MVP/LRP) expression correlate with in vitro daunorubicin resistance in acute myeloid leukemia?
Published in:
1999
By:
- Broxterman, H J;
- Sonneveld, P;
- Pieters, R;
- Lankelma, J;
- Eekman, C A;
- Loonen, A H;
- Schoester, M;
- Ossenkoppele, G J;
- Löwenberg, B;
- Pinedo, H M;
- Schuurhuis, G J
Publication type:
journal article
Differentiation and cell-type-restricted expression of HOXC4, HOXC5 and HOXC6 in myeloid leukemias and normal myeloid cells.
Published in:
1998
By:
- Bijl, J.J.;
- van Oostveen, J W;
- Walboomers, J M;
- Brink, A T;
- Vos, W;
- Ossenkoppele, G J;
- Meijer, C J
Publication type:
journal article
Response to Michele Baccarani.
Published in:
Leukemia (08876924), 1998, v. 12, n. 7, p. 1169, doi. 10.1038/sj.leu.2401064
By:
- Thijsen, S F T;
- Schuurhuis, G J;
- van Oostveen, J W;
- Ossenkoppele, G J
Publication type:
Article
Immunoglobulin and T cell receptor gene rearrangement patterns in acute lymphoblastic leukemia are less mature in adults than in children: implications for selection of PCR targets for detection of minimal residual disease.
Published in:
1998
By:
- Szczepański, T;
- Langerak, A W;
- Wolvers-Tettero, I L M;
- Ossenkoppele, G J;
- Verhoef, G;
- Stul, M;
- Petersen, E J;
- de Bruijn, M A C;
- Veer, MB van’t;
- van Dongen, J J M;
- Szczepański, T;
- Wolvers-Tettero, I L;
- de Bruijn, M A;
- van't Veer, M B;
- van Dongen, J J
Publication type:
journal article
A functional study on the migration of human monocytes to human leukemic cell lines and the role of monocyte chemoattractant protein-1.
Published in:
1997
By:
- Legdeur, M C J C;
- Beelen, R H J;
- Schuurhuis, G J;
- Broekhoven, M G;
- van de Loosdrecht, A A;
- Tekstra, J;
- Langenhuijsen, M M A C;
- Ossenkoppele, G J;
- Legdeur, M C;
- Beelen, R H;
- Langenhuijsen, M M
Publication type:
journal article
Hypersensitivity of bcr-abl-positive progenitors to hyperthermia in patients with chronic myeloid leukemia.
Published in:
1997
By:
- Thijsen, S F T;
- van Oostveen, J W;
- Schuurhuis, G J;
- Theijsmeijer, A P;
- Oudejans, C B M;
- van Wijk, I J;
- Langenhuijsen, M M A C;
- Ossenkoppele, G J;
- Thijsen, S F;
- Oudejans, C B;
- Langenhuijsen, M M
Publication type:
journal article
Theoretical and practical considerations for the measurement of P-glycoprotein function in acute myeloid leukemia.
Published in:
1997
By:
- Broxterman, H J;
- Lankelma, J;
- Pinedo, H M;
- Eekman, C A;
- Währer, D C R;
- Ossenkoppele, G J;
- Schuurhuis, G J;
- Währer, D C
Publication type:
journal article
Molecular analysis of hematopoietic colonies derived from chronic myeloid leukemia patients: interphase fluorescence in situ hybridization compared with RT-PCR.
Published in:
1997
By:
- Thijsen, S F T;
- Schuurhuis, G J;
- van Oostveen, J W;
- Theijsmeijer, A P;
- Langenhuijsen, M M A C;
- Ossenkoppele, G J;
- Thijsen, S F;
- Langenhuijsen, M M
Publication type:
journal article
Sequential development of peripheral T-cell lymphoma in the course of chronic myelogenous leukemia.
Published in:
1990
By:
- Blonk, Marion C.;
- van der Valk, Paul;
- Beverstock, Geoffrey C.;
- Ossenkoppele, Gerrit J.;
- Blonk, M C;
- van der Valk, P;
- Beverstock, G C;
- Ossenkoppele, G J
Publication type:
journal article
Health related quality of life in patients with multiple myeloma undergoing a double transplantation.
Published in:
European Journal of Haematology, 2005, v. 74, n. 2, p. 136, doi. 10.1111/j.1600-0609.2004.00346.x
By:
- Uyl-de Groot, C. A.;
- Buijt, I.;
- Gloudemans, I. J. M.;
- Ossenkoppele, G. J.;
- Berg, H. P.;
- Huijgens, P. C.
Publication type:
Article
Expression of TNF-receptor associated factor 2 correlates with poor progression-free survival time in ABC-like primary nodal diffuse large B-cell lymphomas.
Published in:
Histopathology, 2008, v. 52, n. 5, p. 578, doi. 10.1111/j.1365-2559.2008.02970.x
By:
- van Galen, J. C.;
- Muris, J. J. F.;
- Giroth, C. P. E.;
- Vos, W.;
- Ossenkoppele, G. J.;
- Meijer, C. J. L. M.;
- Oudejans, J. J.
Publication type:
Article
Allogeneic transplantation after reduced-intensity conditioning with fludarabine-CY for both indolent and aggressive lymphoid malignancies.
Published in:
Bone Marrow Transplantation, 2014, v. 49, n. 4, p. 513, doi. 10.1038/bmt.2013.221
By:
- Wondergem, M J;
- Dijkstra, F S;
- Visser, O J;
- Zweegman, S;
- Ossenkoppele, G J;
- Witte, B I;
- Janssen, J J W M
Publication type:
Article
Auto-SCT in refractory celiac disease type II patients unresponsive to cladribine therapy.
Published in:
Bone Marrow Transplantation, 2011, v. 46, n. 6, p. 840, doi. 10.1038/bmt.2010.199
By:
- Tack, G. J.;
- Wondergem, M. J.;
- Al-Toma, A.;
- Verbeek, W. H. M.;
- Schmittel, A.;
- Machado, M. V.;
- Perri, F.;
- Ossenkoppele, G. J.;
- Huijgens, P. C.;
- Schreurs, M. W. J.;
- Mulder, C. J. J.;
- Visser, O. J.
Publication type:
Article
Therapeutic potential of intravenous 67-gallium in non-Hodgkin's lymphoma.
Published in:
European Journal of Haematology, 1993, v. 51, n. 4, p. 206, doi. 10.1111/j.1600-0609.1993.tb00631.x
By:
- Huijgens, P. C.;
- Jonkhoff, A. R.;
- Hoekstra, O. S.;
- Ossenkoppele, G. J.;
- Teule, G. J. J.
Publication type:
Article
Combining counterflow centrifugal elutriation and glycoprotein lb-dependent purification of human megakaryocytes: Efficacy and selectivity.
Published in:
European Journal of Haematology, 1991, v. 47, n. 4, p. 299, doi. 10.1111/j.1600-0609.1991.tb01575.x
By:
- Pampus, E. C. M.;
- Geel, B. J. M.;
- Huijgens, P. C.;
- Wijermans, P. W.;
- Ossenkoppele, G. J.;
- Rodriguez, F.;
- Zevenbergen, A.;
- Langenhuijsen, M. M. A. C.
Publication type:
Article
Imipenem-cilastatin for empirical therapy in neutropenic patients with fever: An open study in patients with hematologic malignancies.
Published in:
European Journal of Haematology, 1991, v. 46, n. 1, p. 42, doi. 10.1111/j.1600-0609.1991.tb00512.x
By:
- Huijgens, P. C.;
- Ossenkoppele, G. J.;
- Weijers, T. F.;
- Loenen, A. C.;
- Simoons-Smit, A. M.;
- Wijermans, P. W.;
- Pampus, E. C. M.;
- Langenhuijsen, M. M. A. C.
Publication type:
Article
High-vs low-dose cytarabine combined with interferon alfa in patients with first chronic phase chronic myeloid leukemia. A prospective randomized phase III study.
Published in:
2007
By:
- Deenik, W.;
- van der Holt, B.;
- Verhoef, G. E. G.;
- Schattenberg, A. V. M. B.;
- Verdonck, L. F.;
- Daenen, S. M. G. J.;
- Zachée, P.;
- Westveer, P. H. M.;
- Smit, W. M.;
- Wittebol, S.;
- Schouten, H. C.;
- Löwenberg, B.;
- Ossenkoppele, G. J.;
- Cornelissen, J. J.;
- Zachée, P;
- Löwenberg, B
Publication type:
journal article
Resistance prediction in AML: analysis of 4601 patients from MRC/NCRI, HOVON/SAKK, SWOG and MD Anderson Cancer Center.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 312, doi. 10.1038/leu.2014.242
By:
- Walter, R B;
- Othus, M;
- Burnett, A K;
- Löwenberg, B;
- Kantarjian, H M;
- Ossenkoppele, G J;
- Hills, R K;
- Ravandi, F;
- Pabst, T;
- Evans, A;
- Pierce, S R;
- Vekemans, M-C;
- Appelbaum, F R;
- Estey, E H
Publication type:
Article
Nilotinib in patients with Ph+ chronic myeloid leukemia in accelerated phase following imatinib resistance or intolerance: 24-month follow-up results.
Published in:
Leukemia (08876924), 2012, v. 26, n. 6, p. 1189, doi. 10.1038/leu.2011.323
By:
- le Coutre, P D;
- Giles, F J;
- Hochhaus, A;
- Apperley, J F;
- Ossenkoppele, G J;
- Blakesley, R;
- Shou, Y;
- Gallagher, N J;
- Baccarani, M;
- Cortes, J;
- Kantarjian, H M
Publication type:
Article
Residual normal stem cells can be detected in newly diagnosed chronic myeloid leukemia patients by a new flow cytometric approach and predict for optimal response to imatinib.
Published in:
Leukemia (08876924), 2012, v. 26, n. 5, p. 977, doi. 10.1038/leu.2011.347
By:
- Janssen, J J W M;
- Deenik, W;
- Smolders, K G M;
- van Kuijk, B J;
- Pouwels, W;
- Kelder, A;
- Cornelissen, J J;
- Schuurhuis, G J;
- Ossenkoppele, G J
Publication type:
Article
Intensified chemotherapy inspired by a pediatric regimen combined with allogeneic transplantation in adult patients with acute lymphoblastic leukemia up to the age of 40.
Published in:
Leukemia (08876924), 2011, v. 25, n. 11, p. 1697, doi. 10.1038/leu.2011.141
By:
- Rijneveld, A W;
- van der Holt, B;
- Daenen, S M G J;
- Biemond, B J;
- de Weerdt, O;
- Muus, P;
- Maertens, J;
- Mattijssen, V;
- Demuynck, H;
- Legdeur, M C J C;
- Wijermans, P W;
- Wittebol, S;
- Spoelstra, F M;
- Dekker, A W;
- Ossenkoppele, G J;
- Willemze, R;
- Cornelissen, J J
Publication type:
Article
Acute leukemias of ambiguous lineage: diagnostic consequences of the WHO2008 classification.
Published in:
Leukemia (08876924), 2010, v. 24, n. 7, p. 1392, doi. 10.1038/leu.2010.119
By:
- van den Ancker, W.;
- Terwijn, M.;
- Westers, T. M.;
- Merle, P. A.;
- van Beckhoven, E.;
- Dräger, A. M.;
- Ossenkoppele, G. J.;
- van de Loosdrecht, A. A.
Publication type:
Article
Aberrant marker expression patterns on the CD34+CD38− stem cell compartment in acute myeloid leukemia allows to distinguish the malignant from the normal stem cell compartment both at diagnosis and in remission.
Published in:
Leukemia (08876924), 2007, v. 21, n. 8, p. 1700, doi. 10.1038/sj.leu.2404754
By:
- van Rhenen, A.;
- Moshaver, B.;
- Kelder, A.;
- Feller, N.;
- Nieuwint, A. W. M.;
- Zweegman, S.;
- Ossenkoppele, G. J.;
- Schuurhuis, G. J.
Publication type:
Article
Flt-3 internal tandem duplication hampers differentiation of AML blasts towards leukemic dendritic cells.
Published in:
2006
By:
- Houtenbos, I;
- Westers, T M;
- Ossenkoppele, G J;
- van de Loosdrecht, A A;
- Hess, C J;
- Waisfisz, Q
Publication type:
Correction Notice
Flt-3 internal tandem duplication hampers differentiation of AML blasts towards leukemic dendritic cells.
Published in:
2006
By:
- Houtenbos, I.;
- Westers, T. M.;
- Ossenkoppele, G. J.;
- van de Loosdrecht, A. A.;
- Hess, C. J.;
- Waisfisz, Q.
Publication type:
Letter
Maintained immunogenicity of chronic myeloid leukemia-derived dendritic cells in the presence of Imatinib mesylate: implication for vaccination regimens.
Published in:
2006
By:
- Westers, T. M.;
- Janssen, J. J. W. M.;
- Houtenbos, I.;
- Snoijs, N. C. L.;
- Van de Loosdrecht, A. A.;
- Ossenkoppele, G. J.
Publication type:
Letter
Leukemia-derived dendritic cells in acute myeloid leukemia exhibit potent migratory capacity.
Published in:
2005
By:
- Westers, T. M.;
- Houtenbos, I.;
- Snoijs, N. C. L.;
- van de Loosdrecht, A. A.;
- Ossenkoppele, G. J.
Publication type:
Letter
Short intensive sequential therapy followed by autologous stem cell transplantation in adult Burkitt, Burkitt-like and lymphoblastic lymphoma.
Published in:
Leukemia (08876924), 2005, v. 19, n. 6, p. 945, doi. 10.1038/sj.leu.2403733
By:
- van Imhoff, G. W.;
- van der Holt, B.;
- MacKenzie, M. A.;
- Ossenkoppele, G. J.;
- Wijermans, P. W.;
- Kramer, M. H. H.;
- van't Veer, M. B.;
- Schouten, H. C.;
- van Marwijk Kooy, M.;
- van Oers, M. H. J.;
- Raemaekers, J. M. M.;
- Sonneveld, P.;
- Meulendijks, L. A. M. H.;
- Kluin, P. M.;
- Kluin-Nelemans, H. C.;
- Verdonck, L. F.
Publication type:
Article
Identification of genes potentially involved in disease transformation of CML.
Published in:
Leukemia (08876924), 2005, v. 19, n. 6, p. 998, doi. 10.1038/sj.leu.2403735
By:
- Janssen, J. J. W. M.;
- Klaver, S. M.;
- Waisfisz, Q.;
- Pasterkamp, G.;
- de Kleijn, D. P. V.;
- Schuurhuis, G. J.;
- Ossenkoppele, G. J.
Publication type:
Article
Gene expression profiling of minimal residual disease in acute myeloid leukaemia by novel multiplex-PCR-based method.
Published in:
Leukemia (08876924), 2004, v. 18, n. 12, p. 1981, doi. 10.1038/sj.leu.2403520
By:
- Hess, C. J.;
- Denkers, F.;
- Ossenkoppele, G. J.;
- Waisfisz, Q.;
- McElgunn, C. J.;
- Eldering, E.;
- Schouten, J. P.;
- Schuurhuis, G. J.
Publication type:
Article
MRD parameters using immunophenotypic detection methods are highly reliable in predicting survival in acute myeloid leukaemia.
Published in:
Leukemia (08876924), 2004, v. 18, n. 8, p. 1380, doi. 10.1038/sj.leu.2403405
By:
- Feller, N;
- Van Der Pol, M. A.;
- Van Stijn, A.;
- Weijers, G. W. W.;
- Westra, A. H.;
- Evertse, B. W.;
- Ossenkoppele, G. J.;
- Schuurhuis, G. J.
Publication type:
Article
TNF-a receptor 1 expression on acute myeloid leukemic blasts predicts differentiation into leukemic dendritic cells.
Published in:
2004
By:
- Houtenbos, I.;
- Westers, T. M.;
- de Gruijl, T. D.;
- Scheper, R. J.;
- Ossenkoppele, G. J.;
- van de Loosdrecht, A. A.
Publication type:
Letter
Secondary imatinib resistance associated with an aberrant bcr-abl fusion gene.
Published in:
2004
By:
- Janssen, J. J. W. M.;
- Hochhaus, A.;
- van Oostveen, J. W.;
- Waisfisz, Q.;
- Schuurhuis, G. J.;
- Ossenkoppele, G. J.
Publication type:
Letter
Minimal residual disease cells in AML patients have an apoptosis-sensitive protein profile.
Published in:
2004
By:
- Van Stijn, A.;
- Kok, A.;
- van Stalborch, M. A.;
- van der Pol, M. A.;
- Feller, N.;
- Westra, A. H.;
- Ossenkoppele, G. J.;
- Schuurhuis, G. J.
Publication type:
Letter
Identification of CD14 as a predictor for leukemic dendritic cell differentiation in acute myeloid leukemia.
Published in:
2003
By:
- Houtenbos, I;
- Westers, T M;
- Ossenkoppele, G J;
- van de Loosdrecht, A A
Publication type:
Letter
Reply to Mohty et al.
Published in:
Leukemia (08876924), 2003, v. 17, n. 8, p. 1685, doi. 10.1038/sj.leu.2403016
By:
- Houtenbos, I;
- Westers, T M;
- Ossenkoppele, G J;
- van de Loosdrecht, A A
Publication type:
Article
Minimal residual disease in acute myeloid leukemia is predicted by P-glycoprotein activity but not by multidrug resistance protein activity at diagnosis.
Published in:
Leukemia (08876924), 2003, v. 17, n. 8, p. 1674, doi. 10.1038/sj.leu.2403025
By:
- van der Pol, M A;
- Feller, N;
- Ossenkoppele, G J;
- Weijers, G W D;
- Westra, A H;
- van Stijn, A;
- Broxterman, H J;
- Schuurhuis, G J
Publication type:
Article
Vaccination of chronic myeloid leukemia patients with autologous in vitro cultured leukemic dendritic cells.
Published in:
Leukemia (08876924), 2003, v. 17, n. 7, p. 1424, doi. 10.1038/sj.leu.2402979
By:
- Ossenkoppele, G J;
- Stam, A G M;
- Westers, T M;
- de Gruijl, T D;
- Janssen, J J W M;
- van de Loosdrecht, A A;
- Scheper, R J
Publication type:
Article

Found: 57