Works by Osawa, Haruhiko

Results: 73

The influence of hypertensive disorders of pregnancy on the development of long-term postpartum type 2 diabetes mellitus.

Published in:

Endocrine Journal, 2025, v. 72, n. 6, p. 727, doi. 10.1507/endocrj.EJ25-0033

By:

Shota Inoue;
Yasunori Takata;
Yasuharu Tabara;
Koutatsu Maruyama;
Ayaka Yoshida;
Haruhiko Osawa;
Takashi Sugiyama

Publication type:

Article

Influence of Insulin Resistance on the Association Between Physical Activity and Heart Rate Variability: The Toon Health Study.

Published in:

Journal of Physical Activity & Health, 2020, v. 17, n. 11, p. 1075, doi. 10.1123/jpah.2020-0110

By:

Saito, Isao;
Maruyama, Koutatsu;
Kato, Tadahiro;
Takata, Yasunori;
Tomooka, Kiyohide;
Kawamura, Ryoichi;
Uesugi, Yuichi;
Naito, Yoshihiko;
Osawa, Haruhiko;
Tanigawa, Takeshi

Publication type:

Article

Circulating resistin is increased with decreasing renal function in a general Japanese population: the Hisayama Study.

Published in:

Nephrology Dialysis Transplantation, 2010, v. 25, n. 10, p. 3236, doi. 10.1093/ndt/gfq155

By:

Kawamura, Ryoichi;
Doi, Yasufumi;
Osawa, Haruhiko;
Ninomiya, Toshiharu;
Hata, Jun;
Yonemoto, Koji;
Tanizaki, Yumihiro;
Iida, Mitsuo;
Makino, Hideichi;
Kiyohara, Yutaka

Publication type:

Article

Association of hematological parameters with insulin resistance, insulin sensitivity, and asymptomatic cerebrovascular damage: The J-SHIP and Toon Health Study.

Published in:

Clinical Hemorheology & Microcirculation, 2013, v. 55, n. 3, p. 297, doi. 10.3233/CH-2012-1634

By:

Tabara, Yasuharu;
Igase, Michiya;
Saito, Isao;
Nishida, Wataru;
Kohara, Katsuhiko;
Sakurai, Susumu;
Kawamura, Ryoichi;
Okada, Yoko;
Hitsumoto, Shinichi;
Onuma, Hiroshi;
Nagai, Tokihisa;
Takata, Yasunori;
Uetani, Eri;
Takita, Rie;
Kido, Tomoko;
Ochi, Namiko;
Osawa, Haruhiko;
Tanigawa, Takeshi;
Miki, Tetsuro

Publication type:

Article

The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMA-IR in Japanese population.

Published in:

Journal of Human Genetics, 2010, v. 55, n. 9, p. 600, doi. 10.1038/jhg.2010.75

By:

Onuma, Hiroshi;
Tabara, Yasuharu;
Kawamoto, Ryuichi;
Shimizu, Ikki;
Kawamura, Ryoichi;
Takata, Yasunori;
Nishida, Wataru;
Ohashi, Jun;
Miki, Tetsuro;
Kohara, Katsuhiko;
Makino, Hideichi;
Osawa, Haruhiko

Publication type:

Article

Construction of a prediction model for type 2 diabetes mellitus in the Japanese population based on 11 genes with strong evidence of the association.

Published in:

Journal of Human Genetics, 2009, v. 54, n. 4, p. 236, doi. 10.1038/jhg.2009.17

By:

Miyake, Kazuaki;
Woosung Yang;
Hara, Kazuo;
Yasuda, Kazuki;
Horikawa, Yukio;
Osawa, Haruhiko;
Furuta, Hiroto;
Ng, Maggie C. Y.;
Hirota, Yushi;
Mori, Hiroyuki;
Ido, Keisuke;
Yamagata, Kazuya;
Hinokio, Yoshinori;
Oka, Yoshitomo;
Iwasaki, Naoko;
Iwamoto, Yasuhiko;
Yamada, Yuichiro;
Seino, Yutaka;
Maegawa, Hiroshi;
Kashiwagi, Atsunori

Publication type:

Article

Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects.

Published in:

Journal of Human Genetics, 2008, v. 53, n. 2, p. 174, doi. 10.1007/s10038-007-0231-5

By:

Miyake, Kazuaki;
Horikawa, Yukio;
Hara, Kazuo;
Yasuda, Kazuki;
Osawa, Haruhiko;
Furuta, Hiroto;
Hirota, Yushi;
Yamagata, Kazuya;
Hinokio, Yoshinori;
Oka, Yoshitomo;
Iwasaki, Naoko;
Iwamoto, Yasuhiko;
Yamada, Yuichiro;
Seino, Yutaka;
Maegawa, Hiroshi;
Kashiwagi, Atsunori;
Yamamoto, Ken;
Tokunaga, Katsushi;
Takeda, Jun;
Makino, Hideichi

Publication type:

Article

Practice guideline: Statement regarding treatment for suspected slowly progressive type 1 diabetes (SPIDDM; probable) cases (English version).

Published in:

2025

By:

Shimada, Akira;
Kawasaki, Eiji;
Abiru, Norio;
Awata, Takuya;
Oikawa, Yoichi;
Osawa, Haruhiko;
Kajio, Hiroshi;
Kozawa, Junji;
Takahashi, Kazuma;
Chujo, Daisuke;
Noso, Shinsuke;
Fukui, Tomoyasu;
Miura, Junnosuke;
Yasuda, Kazuki;
Yasuda, Hisafumi;
Imagawa, Akihisa;
Ikegami, Hiroshi

Publication type:

Case Study

Prediction of future insulin‐deficiency in glutamic acid decarboxylase autoantibody enzyme‐linked immunosorbent assay‐positive patients with slowly‐progressive type 1 diabetes.

Published in:

Journal of Diabetes Investigation, 2024, v. 15, n. 7, p. 835, doi. 10.1111/jdi.14178

By:

Kawasaki, Eiji;
Awata, Takuya;
Ikegami, Hiroshi;
Imagawa, Akihisa;
Oikawa, Yoichi;
Osawa, Haruhiko;
Katsuki, Takeshi;
Kanatsuna, Norio;
Kawamura, Ryoichi;
Kozawa, Junji;
Kodani, Noriko;
Kobayashi, Tetsuro;
Shimada, Akira;
Shimoda, Masayuki;
Takahashi, Kazuma;
Chujo, Daisuke;
Tsujimoto, Tetsuro;
Tsuchiya, Kyoichiro;
Terakawa, Aiko;
Terasaki, Jungo

Publication type:

Article

Interaction effect between low birthweight and resistin gene rs1862513 variant on insulin resistance and type 2 diabetes mellitus in adulthood: Toon Genome Study.

Published in:

Journal of Diabetes Investigation, 2024, v. 15, n. 6, p. 725, doi. 10.1111/jdi.14163

By:

Yoshida, Ayaka;
Takata, Yasunori;
Tabara, Yasuharu;
Maruyama, Koutatsu;
Inoue, Shota;
Osawa, Haruhiko;
Sugiyama, Takashi

Publication type:

Article

New diagnostic criteria (2023) for slowly progressive type 1 diabetes (SPIDDM): Report from Committee on Type 1 Diabetes of the Japan Diabetes Society (English version).

Published in:

2024

By:

Shimada, Akira;
Kawasaki, Eiji;
Abiru, Norio;
Awata, Takuya;
Oikawa, Yoichi;
Osawa, Haruhiko;
Kajio, Hiroshi;
Kozawa, Junji;
Takahashi, Kazuma;
Chujo, Daisuke;
Noso, Shinsuke;
Fukui, Tomoyasu;
Miura, Junnosuke;
Yasuda, Kazuki;
Yasuda, Hisafumi;
Imagawa, Akihisa;
Ikegami, Hiroshi

Publication type:

Case Study

Resistin G–A haplotype at SNP‐420/‐358 is associated with the latent sarcopenic obesity index in the toon genome study.

Published in:

Journal of Diabetes Investigation, 2023, v. 14, n. 5, p. 686, doi. 10.1111/jdi.13998

By:

Ikeda, Yosuke;
Kawamura, Ryoichi;
Takata, Yasunori;
Tabara, Yasuharu;
Maruyama, Koutatsu;
Takakado, Misaki;
Hadate, Toshimi;
Ohashi, Jun;
Saito, Isao;
Ogawa, Yoshihiro;
Osawa, Haruhiko

Publication type:

Article

Bivalent GAD autoantibody ELISA improves clinical utility and risk prediction for adult autoimmune diabetes.

Published in:

Journal of Diabetes Investigation, 2023, v. 14, n. 4, p. 570, doi. 10.1111/jdi.13980

By:

Kawasaki, Eiji;
Shimada, Akira;
Imagawa, Akihisa;
Abiru, Norio;
Awata, Takuya;
Oikawa, Yoichi;
Osawa, Haruhiko;
Kawabata, Yumiko;
Kozawa, Junji;
Kobayashi, Tetsuro;
Takahashi, Kazuma;
Chujo, Daisuke;
Fukui, Tomoyasu;
Miura, Junnosuke;
Yasuda, Kazuki;
Yasuda, Hisafumi;
Kajio, Hiroshi;
Hanafusa, Toshiaki;
Ikegami, Hiroshi

Publication type:

Article

Comparing the clinical significance and antigen specificity of insulinoma‐associated antigen‐2 autoantibodies between radioimmunoassay and enzyme‐linked immunosorbent assay in Japanese patients with type 1 diabetes.

Published in:

Journal of Diabetes Investigation, 2023, v. 14, n. 1, p. 58, doi. 10.1111/jdi.13910

By:

Kawasaki, Eiji;
Shimada, Akira;
Imagawa, Akihisa;
Abiru, Norio;
Awata, Takuya;
Oikawa, Yoichi;
Osawa, Haruhiko;
Kawabata, Yumiko;
Kozawa, Junji;
Kobayashi, Tetsuro;
Takahashi, Kazuma;
Chujo, Daisuke;
Fukui, Tomoyasu;
Miura, Junnosuke;
Yasuda, Kazuki;
Yasuda, Hisafumi;
Kajio, Hiroshi;
Hanafusa, Toshiaki;
Ikegami, Hiroshi

Publication type:

Article

Poor glycemic control rather than types of diabetes is a risk factor for sarcopenia in diabetes mellitus: The MUSCLES‐DM study.

Published in:

Journal of Diabetes Investigation, 2022, v. 13, n. 11, p. 1881, doi. 10.1111/jdi.13882

By:

Hiromine, Yoshihisa;
Noso, Shinsuke;
Rakugi, Hiromi;
Sugimoto, Ken;
Takata, Yasunori;
Katsuya, Tomohiro;
Fukuda, Masahiro;
Akasaka, Hiroshi;
Osawa, Haruhiko;
Tabara, Yasuharu;
Ikegami, Hiroshi

Publication type:

Article

Low birthweight is associated with type 2 diabetes mellitus in Japanese adults: The Toon Health Study.

Published in:

Journal of Diabetes Investigation, 2020, v. 11, n. 6, p. 1643, doi. 10.1111/jdi.13274

By:

Yokoyama, Maki;
Saito, Isao;
Ueno, Megumi;
Kato, Hiroaki;
Yoshida, Ayaka;
Kawamura, Ryoichi;
Maruyama, Koutatsu;
Takata, Yasunori;
Osawa, Haruhiko;
Tanigawa, Takeshi;
Sugiyama, Takashi

Publication type:

Article

Japanese Clinical Practice Guideline for Diabetes 2019.

Published in:

Journal of Diabetes Investigation, 2020, v. 11, n. 4, p. 1020, doi. 10.1111/jdi.13306

By:

Araki, Eiichi;
Goto, Atsushi;
Kondo, Tatsuya;
Noda, Mitsuhiko;
Noto, Hiroshi;
Origasa, Hideki;
Osawa, Haruhiko;
Taguchi, Akihiko;
Tanizawa, Yukio;
Tobe, Kazuyuki;
Yoshioka, Narihito

Publication type:

Article

Ratios of serum eicosapentaenoic acid to arachidonic acid and docosahexaenoic acid to arachidonic acid were inversely associated with serum resistin levels: The Hisayama Study.

Published in:

Journal of Diabetes Investigation, 2020, v. 11, n. 2, p. 482, doi. 10.1111/jdi.13129

By:

Higashioka, Mayu;
Hirakawa, Yoichiro;
Kawamura, Ryoichi;
Honda, Takanori;
Hata, Jun;
Yoshida, Daigo;
Takata, Yasunori;
Kitazono, Takanari;
Osawa, Haruhiko;
Ninomiya, Toshiharu

Publication type:

Article

Hyperglycemia in non‐obese patients with type 2 diabetes is associated with low muscle mass: The Multicenter Study for Clarifying Evidence for Sarcopenia in Patients with Diabetes Mellitus.

Published in:

Journal of Diabetes Investigation, 2019, v. 10, n. 6, p. 1471, doi. 10.1111/jdi.13070

By:

Sugimoto, Ken;
Tabara, Yasuharu;
Ikegami, Hiroshi;
Takata, Yasunori;
Kamide, Kei;
Ikezoe, Tome;
Kiyoshige, Eri;
Makutani, Yukako;
Onuma, Hiroshi;
Gondo, Yasuyuki;
Ikebe, Kazunori;
Ichihashi, Noriaki;
Tsuboyama, Tadao;
Matsuda, Fumihiko;
Kohara, Katsuhiko;
Kabayama, Mai;
Fukuda, Masahiro;
Katsuya, Tomohiro;
Osawa, Haruhiko;
Hiromine, Yoshihisa

Publication type:

Article

Variants in the BACH2 and CLEC16A gene might be associated with susceptibility to insulin‐triggered type 1 diabetes.

Published in:

Journal of Diabetes Investigation, 2019, v. 10, n. 6, p. 1447, doi. 10.1111/jdi.13057

By:

Onuma, Hiroshi;
Kawamura, Ryoichi;
Tabara, Yasuharu;
Yamashita, Masakatsu;
Ohashi, Jun;
Kawasaki, Eiji;
Imagawa, Akihisa;
Yamada, Yuya;
Chujo, Daisuke;
Takahashi, Kenji;
Suehiro, Tadashi;
Takata, Yasunori;
Osawa, Haruhiko;
Makino, Hideichi

Publication type:

Article

Endoplasmic reticulum stress induced by tunicamycin increases resistin messenger ribonucleic acid through the pancreatic endoplasmic reticulum eukaryotic initiation factor 2α kinase-activating transcription factor 4-CAAT/enhancer binding protein-α homologous protein pathway in THP-1 human monocytes

Published in:

Journal of Diabetes Investigation, 2016, v. 7, n. 3, p. 312, doi. 10.1111/jdi.12434

By:

Hamada, Junpei;
Onuma, Hiroshi;
Ochi, Fumihiro;
Hirai, Hiroki;
Takemoto, Koji;
Miyoshi, Akiko;
Matsushita, Manami;
Kadota, Yuko;
Ohashi, Jun;
Kawamura, Ryoichi;
Takata, Yasunori;
Nishida, Wataru;
Hashida, Seiichi;
Ishii, Eiichi;
Osawa, Haruhiko

Publication type:

Article

Diagnostic criteria for acute-onset type 1 diabetes mellitus (2012): Report of the Committee of Japan Diabetes Society on the Research of Fulminant and Acute- onset Type 1 Diabetes Mellitus.

Published in:

Journal of Diabetes Investigation, 2014, v. 5, n. 1, p. 115, doi. 10.1111/jdi.12119

By:

Kawasaki, Eiji;
Maruyama, Taro;
Imagawa, Akihisa;
Awata, Takuya;
Ikegami, Hiroshi;
Uchigata, Yasuko;
Osawa, Haruhiko;
Kawabata, Yumiko;
Kobayashi, Tetsuro;
Shimada, Akira;
Shimizu, Ikki;
Takahashi, Kazuma;
Nagata, Masao;
Makino, Hideichi;
Hanafusa, Toshiaki

Publication type:

Article

Report of the Committee of the Japan Diabetes Society on the Research of Fulminant and Acute-onset Type 1 Diabetes Mellitus: New diagnostic criteria of fulminant type 1 diabetes mellitus (2012).

Published in:

Journal of Diabetes Investigation, 2012, v. 3, n. 6, p. 536, doi. 10.1111/jdi.12024

By:

Imagawa, Akihisa;
Hanafusa, Toshiaki;
Awata, Takuya;
Ikegami, Hiroshi;
Uchigata, Yasuko;
Osawa, Haruhiko;
Kawasaki, Eiji;
Kawabata, Yumiko;
Kobayashi, Tetsuro;
Shimada, Akira;
Shimizu, Ikki;
Takahashi, Kazuma;
Nagata, Masao;
Makino, Hideichi;
Maruyama, Taro

Publication type:

Article

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

Published in:

Nature Genetics, 2008, v. 40, n. 9, p. 1092, doi. 10.1038/ng.207

By:

Yasuda, Kazuki;
Miyake, Kazuaki;
Horikawa, Yukio;
Hara, Kazuo;
Osawa, Haruhiko;
Furuta, Hiroto;
Hirota, Yushi;
Mori, Hiroyuki;
Jonsson, Anna;
Sato, Yoshifumi;
Yamagata, Kazuya;
Hinokio, Yoshinori;
Wang, He-Yao;
Tanahashi, Toshihito;
Nakamura, Naoto;
Oka, Yoshitomo;
Iwasaki, Naoko;
Iwamoto, Yasuhiko;
Yamada, Yuichiro;
Seino, Yutaka

Publication type:

Article

The impact of masticatory ability as evaluated by salivary flow rates on obesity in japanese: The Toon health study.

Published in:

Obesity (19307381), 2015, v. 23, n. 6, p. 1296, doi. 10.1002/oby.21071

By:

Maruyama, Koutatsu;
Nishioka, Shinji;
Miyoshi, Noriko;
Higuchi, Kana;
Mori, Hiromi;
Tanno, Sakurako;
Tomooka, Kiyohide;
Eguchi, Eri;
Furukawa, Shinya;
Saito, Isao;
Sakurai, Susumu;
Nishida, Wataru;
Osawa, Haruhiko;
Tanigawa, Takeshi

Publication type:

Article

An inverse association between serum resistin levels and n-3 polyunsaturated fatty acids intake was strongest in the SNP-420 G/G genotype in the Japanese cohort: The Toon Genome Study.

Published in:

Clinical Endocrinology, 2018, v. 88, n. 1, p. 51, doi. 10.1111/cen.13500

By:

Noumi, Yukinobu;
Kawamura, Ryoichi;
Tabara, Yasuharu;
Maruyama, Koutatsu;
Takata, Yasunori;
Nishida, Wataru;
Okamoto, Ai;
Nishimiya, Tatsuya;
Onuma, Hiroshi;
Saito, Isao;
Tanigawa, Takeshi;
Osawa, Haruhiko

Publication type:

Article

PPARγ Pro12Ala Pro/Pro and resistin SNP-420 G/G genotypes are synergistically associated with plasma resistin in the Japanese general population.

Published in:

Clinical Endocrinology, 2009, v. 71, n. 3, p. 341, doi. 10.1111/j.1365-2265.2008.03465.x

By:

Osawa, Haruhiko;
Tabara, Yasuharu;
Kawamoto, Ryuichi;
Ohashi, Jun;
Ochi, Masaaki;
Onuma, Hiroshi;
Nishida, Wataru;
Yamada, Kazuya;
Nakura, Jun;
Miki, Tetsuro;
Makino, Hideichi;
Kohara, Katsuhiko

Publication type:

Article

The G/G genotype of a single nucleotide polymorphism at –1066 of c-Jun N-terminal kinase 1 gene ( MAPK8) does not affect type 2 diabetes susceptibility despite the specific binding of AP2α.

Published in:

Clinical Endocrinology, 2008, v. 69, n. 1, p. 36, doi. 10.1111/j.1365-2265.2007.03143.x

By:

Osawa, Haruhiko;
Yamada, Kazuya;
Tabara, Yasuharu;
Ochi, Masaaki;
Onuma, Hiroshi;
Nishida, Wataru;
Shimizu, Ikki;
Kawamoto, Ryuichi;
Fujii, Yasuhisa;
Miki, Tetsuro;
Ohashi, Jun;
Makino, Hideichi

Publication type:

Article

Serum resistin is positively correlated with the accumulation of metabolic syndrome factors in type 2 diabetes.

Published in:

Clinical Endocrinology, 2008, v. 69, n. 1, p. 74, doi. 10.1111/j.1365-2265.2007.03154.x

By:

Osawa, Haruhiko;
Ochi, Masaaki;
Tabara, Yasuharu;
Kato, Kenichi;
Yamauchi, Junko;
Takata, Yasunori;
Nishida, Wataru;
Onuma, Hiroshi;
Shimizu, Ikki;
Fujii, Yasuhisa;
Miki, Tetsuro;
Ohashi, Jun;
Makino, Hideichi

Publication type:

Article

Serum total and high molecular weight adiponectin levels are correlated with the severity of diabetic retinopathy and nephropathy.

Published in:

Clinical Endocrinology, 2008, v. 68, n. 3, p. 442, doi. 10.1111/j.1365-2265.2007.03063.x

By:

Kato, Kenichi;
Osawa, Haruhiko;
Ochi, Masaaki;
Kusunoki, Yukiko;
Ebisui, Osamu;
Ohno, Keizo;
Ohashi, Jun;
Shimizu, Ikki;
Fujii, Yasuhisa;
Tanimoto, Mitsune;
Makino, Hideichi

Publication type:

Article

A simple precipitation method for measuring sialic acid in apolipoprotein B-containing lipoproteins in plasma.

Published in:

Annals of Clinical Biochemistry, 2005, v. 42, n. 4, p. 298, doi. 10.1258/0004563054255614

By:

Shishino, Koji;
Yoshioka, Yuki;
Hashimoto, Kaori;
Ochi, Masaaki;
Aono, Kenji;
Murase, Mitsuharu;
Osawa, Haruhiko;
Makino, Hideichi;
Saheki, Shuichi

Publication type:

Article

Clinical and Genetic Characteristics of Non-Insulin-Requiring Glutamic Acid Decarboxylase (GAD) Autoantibody-Positive Diabetes: A Nationwide Survey in Japan.

Published in:

PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0155643

By:

Yasui, Junichi;
Kawasaki, Eiji;
Tanaka, Shoichiro;
Awata, Takuya;
Ikegami, Hiroshi;
Imagawa, Akihisa;
Uchigata, Yasuko;
Osawa, Haruhiko;
Kajio, Hiroshi;
Kawabata, Yumiko;
Shimada, Akira;
Takahashi, Kazuma;
Yasuda, Kazuki;
Yasuda, Hisafumi;
Hanafusa, Toshiaki;
Kobayashi, Tetsuro;
null, null

Publication type:

Article

CDH13 genotype-dependent association of high-molecular weight adiponectin with all-cause mortality: the J-SHIPP study.

Published in:

2014

By:

Uetani, Eri;
Tabara, Yasuharu;
Kawamoto, Ryuichi;
Onuma, Hiroshi;
Kohara, Katsuhiko;
Osawa, Haruhiko;
Miki, Tetsuro

Publication type:

journal article

CDH13 Genotype--Dependent Association of High--Molecular Weight Adiponectin With All-Cause Mortality: The J-SHIPP Study.

Published in:

Diabetes Care, 2014, v. 37, n. 2, p. 396, doi. 10.2337/dc13-1658

By:

Eri Uetani;
Yasuharu Tabara;
Ryuichi Kawamoto;
Hiroshi Onuma;
Katsuhiko Kohara;
Haruhiko Osawa;
Tetsuro Miki

Publication type:

Article

Pancreas Histology and a Longitudinal Study of Insulin Secretion in a Japanese Patient With Latent Autoimmune Diabetes in Adults.

Published in:

Diabetes Care, 2008, v. 31, n. 10, p. e69, doi. 10.2337/dc08-1082

By:

SATOSHI MURAO;
AKIHISA IMAGAWA;
EIJI KAWASAKI;
KAZUAKI YOKOTA;
TETSUJI YAMASHITA;
TAKASHI SEKIKAWA;
HARUHIKO OSAWA;
TOSHIAKI HANAFUSA;
HIDEICHI MAKINO

Publication type:

Article

Plasma Resistin, Associated With Single Nucleotide Polymorphism -420, Is Correlated With Insulin Resistance, Lower HDL Cholesterol, and High-Sensitivity C-Reactive Protein in the Japanese General Population.

Published in:

Diabetes Care, 2007, v. 30, n. 6, p. 1501, doi. 10.2337/dc06-1936

By:

Osawa, Haruhiko;
Tabara, Yasuharu;
Kawamoto, Ryuichi;
Ohashi, Jun;
Ochi, Masaaki;
Onuma, Hiroshi;
Nishida, Wataru;
Yamada, Kazuya;
Nakura, Jun;
Kohara, Katsuhiko;
Miki, Tetsuro;
Makino, Hideichi

Publication type:

Article

The Clinical Heterogeneity of Adult-Onset Diabetic Patients With GAD Autoantibodies in Japan.

Published in:

2002

By:

Kawasaki, Eiji;
Osawa, Haruhiko;
Makino, Hideichi

Publication type:

Letter

Clinical, autoimmune, and genetic characteristics of adult-onset diabetic patients with GAD autoantibodies in Japan (Ehime Study).

Published in:

2002

By:

Takeda, Haruyo;
Yamawaki, Takashi;
Onuma, Hiroshi;
Osawa, Haruhiko;
Makino, Hideichi;
Nishimiya, Tatsuya;
Kawasaki, Eiji;
Shimizu, Ikki;
Fujii, Yasuhisa;
Kato, Kenichi;
Konoue, Etsushi;
Kondo, Shiori;
Fujiyama, Masao;
Murao, Satoshi;
Tanaka, Kiyonobu;
Takada, Yasuharu;
Mori, Kennichi;
Kitsuki, Nobuaki;
Tarumi, Yopshinao;
Kaino, Yukikazu

Publication type:

journal article

A complete deficiency of coagulation factor XIII A-subunit due to a novel compound heterozygote of Ser 413 Leu missense and an nt 389 (ins G) frameshift mutation.

Published in:

British Journal of Haematology, 1999, v. 107, n. 4, p. 772, doi. 10.1046/j.1365-2141.1999.01764.x

By:

Niiya, Toshiyuki;
Osawa, Haruhiko;
Bando, Shiro;
Oto, Yoshiko;
Tokuda, Kiriko;
Takeda, Namiko;
Sumioka, Maki;
Murase, Mitsuharu;
Kida, Kaichi;
Makino, Hideichi;
Makino

Publication type:

Article

Reduction of phosphodiesterase 3B gene expression in peroxisome proliferator-activated receptor γ (+/−) mice independent of adipocyte size

Published in:

FEBS Letters, 2003, v. 542, n. 1-3, p. 65, doi. 10.1016/S0014-5793(03)00339-9

By:

Ogura, Takahiro;
Osawa, Haruhiko;
Tang, Yan;
Onuma, Hiroshi;
Ochi, Masaaki;
Nishimiya, Tatsuya;
Kubota, Naoto;
Terauchi, Yasuo;
Kadowaki, Takashi;
Makino, Hideichi

Publication type:

Article

Dual Effects of a RETN Single Nucleotide Polymorphism (SNP) at -420 on Plasma Resistin: Genotype and DNA Methylation.

Published in:

2016

By:

Onuma, Hiroshi;
Tabara, Yasuharu;
Kawamura, Ryoichi;
Ohashi, Jun;
Nishida, Wataru;
Takata, Yasunori;
Ochi, Masaaki;
Nishimiya, Tatsuya;
Ohyagi, Yasumasa;
Kawamoto, Ryuichi;
Kohara, Katsuhiko;
Miki, Tetsuro;
Osawa, Haruhiko

Publication type:

journal article

Insulin Administration May Trigger Type 1 Diabetes in Japanese Type 2 Diabetes Patients With Type 1 Diabetes High-Risk HLA Class II and the Insulin Gene VNTR Genotype.

Published in:

2014

By:

Nishida, Wataru;
Nagata, Masao;
Imagawa, Akihisa;
Hanafusa, Toshiaki;
Ohashi, Jun;
Takahashi, Kenji;
Suehiro, Tadashi;
Yamada, Yuya;
Chujo, Daisuke;
Kawasaki, Eiji;
Kawamura, Ryoichi;
Onuma, Hiroshi;
Osawa, Haruhiko;
Makino, Hideichi

Publication type:

Journal Article

Reduced High-Molecular-Weight Adiponectin and Elevated High-Sensitivity C-Reactive Protein Are Synergistic Risk Factors for Metabolic Syndrome in a Large-Scale Middle-Aged to Elderly Population: the Shimanami Health Promoting Program Study.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2008, v. 93, n. 3, p. 715, doi. 10.1210/jc.2007-0397

By:

Yasuharu Tabara;
Haruhiko Osawa;
Ryuichi Kawamoto;
Rieko Tachibana-Iimori;
Miyuki Yamamoto;
Jun Nakura;
Tetsuro Miki;
Hideich Makino;
Katsuhiko Kohara

Publication type:

Article

Serum microRNA‐501‐3p is a potential diagnostic tool for detecting mild cognitive impairment: Ehime genome study.

Published in:

Journal of Neurochemistry, 2023, v. 166, n. 6, p. 960, doi. 10.1111/jnc.15911

By:

Toyama, Kensuke;
Spin, Joshua M.;
Tsao, Philip S.;
Maruyama, Koutatsu;
Osawa, Haruhiko;
Mogi, Masaki;
Takata, Yasunori

Publication type:

Article

Genetic variation in the RETN promoter, accompanied by latent sarcopenic obesity, led to insulin resistance in a Japanese cohort: the Toon Genome Study.

Published in:

Diabetologia, 2025, v. 68, n. 4, p. 854, doi. 10.1007/s00125-024-06322-1

By:

Ikeda, Yosuke;
Kawamura, Ryoichi;
Tabara, Yasuharu;
Maruyama, Koutatsu;
Shiokawa, Daisuke;
Takakado, Misaki;
Hadate, Toshimi;
Takata, Yasunori;
Ohashi, Jun;
Saito, Isao;
Ogawa, Yoshihiro;
Osawa, Haruhiko

Publication type:

Article

Association of Fish and Omega-3 Fatty Acid Intake with Carotid Intima-Media Thickness in Middle-Aged to Elderly Japanese Men and Women: The Toon Health Study.

Published in:

Nutrients, 2022, v. 14, n. 17, p. 3644, doi. 10.3390/nu14173644

By:

Maruyama, Koutatsu;
Khairunnisa, Salsabila;
Saito, Isao;
Tanigawa, Takeshi;
Tomooka, Kiyohide;
Minato-Inokawa, Satomi;
Sano, Madoka;
Takakado, Misaki;
Kawamura, Ryoichi;
Takata, Yasunori;
Osawa, Haruhiko

Publication type:

Article

Adipocyte-specific reduction of phosphodiesterase 3B gene expression and its restoration by JTT-501 in the obese, diabetic KKAy mouse.

Published in:

European Journal of Endocrinology, 2001, v. 145, n. 1, p. 93, doi. 10.1530/eje.0.1450093

By:

Yan Tang;
Osawa, Haruhiko;
Onuma, Hiroshi;
Hasegawa, Masaaki;
Nishimiya, Tatsuya;
Ochi, Masaaki;
Makino, Hideichi

Publication type:

Article

A prediction model for estimating NT‐proBNP in a general Japanese population: the Toon Health Study.

Published in:

ESC Heart Failure, 2024, v. 11, n. 3, p. 1483, doi. 10.1002/ehf2.14691

By:

Inoue, Katsuji;
Yamamoto, Kazumichi;
Higashi, Haruhiko;
Takata, Yasunori;
Inaba, Shinji;
Miyazaki, Shigehiro;
Higaki, Akinori;
Saito, Makoto;
Osawa, Haruhiko;
Yamaguchi, Osamu

Publication type:

Article

No Association Between INSIG2 Gene rs7566605 Polymorphism and Being Overweight in Japanese Population.

Published in:

Obesity (19307381), 2008, v. 16, n. 1, p. 211, doi. 10.1038/oby.2007.25

By:

Tabara, Yasuharu;
Kawamoto, Ryuichi;
Osawa, Haruhiko;
Nakura, Jun;
Makino, Hideichi;
Miki, Tetsuro;
Kohara, Katsuhiko

Publication type:

Article

Pulse rate variability and health-related quality of life assessment with the Short Form-8 Japanese version in the general Japanese population.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-54748-9

By:

Saito, Isao;
Maruyama, Koutatsu;
Yamauchi, Kanako;
Funakoshi, Yayoi;
Kato, Tadahiro;
Kawamura, Ryoichi;
Takata, Yasunori;
Osawa, Haruhiko

Publication type:

Article