Works by Organ, Michael G.

Results: 90

Impact of N‐Aryl‐ and NHC Core‐Substituents on the Coupling of Alkylzinc Nucleophiles: Is Bigger always Better?

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 35, p. 1, doi. 10.1002/chem.202200665

By:

Eckert, Philip;
Organ, Michael G.

Publication type:

Article

2,2′-Azobis(2-methylpropionitrile)-Mediated Alkyne Hydrostannylation: Reaction Mechanism.

Published in:

Angewandte Chemie, 2013, v. 125, n. 43, p. 11544, doi. 10.1002/ange.201303736

By:

Oderinde, Martins S.;
Froese, Robert D. J.;
Organ, Michael G.

Publication type:

Article

Pd-PEPPSI-IPentCl: A Highly Effective Catalyst for the Selective Cross-Coupling of Secondary Organozinc Reagents.

Published in:

Angewandte Chemie, 2012, v. 124, n. 45, p. 11516, doi. 10.1002/ange.201205747

By:

Pompeo, Matthew;
Froese, Robert D. J.;
Hadei, Niloufar;
Organ, Michael G.

Publication type:

Article

Studies on the Mechanism of B(C6F5)3-Catalyzed Hydrostannylation of Propargylic Alcohol Derivatives.

Published in:

Angewandte Chemie, 2012, v. 124, n. 39, p. 9972, doi. 10.1002/ange.201204060

By:

Oderinde, Martins S.;
Organ, Michael G.

Publication type:

Article

Higher-Order Zincates as Transmetalators in Alkyl-Alkyl Negishi Cross-Coupling.

Published in:

Angewandte Chemie, 2012, v. 124, n. 28, p. 7130, doi. 10.1002/ange.201203547

By:

McCann, Lucas C.;
Hunter, Howard N.;
Clyburne, Jason A. C.;
Organ, Michael G.

Publication type:

Article

Die Entwicklung raumerfüllender Palladium-NHC-Komplexe für anspruchsvollste Kreuzkupplungsreaktionen.

Published in:

Angewandte Chemie, 2012, v. 124, n. 14, p. 3370, doi. 10.1002/ange.201106131

By:

Valente, Cory;
Çalimsiz, Selçuk;
Hoi, Ka Hou;
Mallik, Debasis;
Sayah, Mahmoud;
Organ, Michael G.

Publication type:

Article

Differentiating CBr and CCl Bond Activation by Using Solvent Polarity: Applications to Orthogonal Alkyl-Alkyl Negishi Reactions.

Published in:

Angewandte Chemie, 2011, v. 123, n. 17, p. 3982, doi. 10.1002/ange.201100705

By:

Hadei, Niloufar;
Achonduh, George T.;
Valente, Cory;
O'Brien, Christopher J.;
Organ, Michael G.

Publication type:

Article

Pd-PEPPSI-IPent: Low-Temperature Negishi Cross-Coupling for the Preparation of Highly Functionalized, Tetra- ortho-Substituted Biaryls.

Published in:

Angewandte Chemie, 2010, v. 122, n. 11, p. 2058, doi. 10.1002/ange.200906811

By:

Çalimsiz, Selçuk;
Sayah, Mahmoud;
Mallik, Debasis;
Organ, Michael G.

Publication type:

Article

Catalysis in Capillaries by Pd Thin Films Using Microwave-Assisted Continuous-Flow Organic Synthesis (MACOS)This work was funded by the Ontario Research and Development Challenge Fund (ORDCF), Canada Foundation for Innovation (CFI), the Ontario Innovation Trust (OIT), NSERC, and York University. The authors are grateful to Biotage Inc. for the donation of a Smith Creator Synthesizer to develop this new methodology. We acknowledge Ross Davidson at Surface Science Western, University of Western Ontario, London, ON, for the SEM and EDX measurements.

Published in:

Angewandte Chemie, 2006, v. 118, n. 17, p. 2827, doi. 10.1002/ange.200503600

By:

Gjergji Shore;
Sylvie Morin;
Michael G. Organ

Publication type:

Article

Sampling and Analysis in Flow: The Keys to Smarter, More Controllable, and Sustainable Fine‐Chemical Manufacturing.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 38, p. 20606, doi. 10.1002/anie.202102009

By:

Morin, Mathieu A.;
Zhang, Wenyao;
Mallik, Debasis;
Organ, Michael G.

Publication type:

Article

Salt to Taste: The Critical Roles Played by Inorganic Salts in Organozinc Formation and in the Negishi Reaction.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 22, p. 12224, doi. 10.1002/anie.202010917

By:

Eckert, Philip;
Sharif, Sepideh;
Organ, Michael G.

Publication type:

Article

Pd-PEPPSI-IPentCl-Catalyzed Amination Using Aminotriphenylsilane as an Ammonia Surrogate.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 11, p. 1510, doi. 10.1002/ejoc.201601565

By:

Lombardi, Christopher;
Mitchell, David;
Rodriguez, Michael J.;
Organ, Michael G.

Publication type:

Article

Iodolactonization: Synthesis, Stereocontrol, and Compatibility Studies.

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 1, p. 175, doi. 10.1002/ejoc.201101343

By:

Oderinde, Martins S.;
Hunter, Howard N.;
Bremner, Stacy W.;
Organ, Michael G.

Publication type:

Article

The Synthesis of Stereodefined Trisubstituted Olefins From Olefin Templates Using Pd Catalysis - Synthesis of the Antihypertensive Isbogrel.

Published in:

European Journal of Organic Chemistry, 2011, v. 2011, n. 27, p. 5374, doi. 10.1002/ejoc.201100849

By:

Rogers, Lawrence R.;
Konstantinou, Zissis;
Reddy, Madhav;
Organ, Michael G.

Publication type:

Article

Pd-PEPPSI-IPent-SiO2: A Supported Catalyst for Challenging Negishi Coupling Reactions in Flow.

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 43, p. 13347, doi. 10.1002/anie.201708598

By:

Price, Gregory A.;
Hassan, Abbas;
Chandrasoma, Nalin;
Bogdan, Andrew R.;
Djuric, Stevan W.;
Organ, Michael G.

Publication type:

Article

Selective Monoarylation of Primary Amines Using the Pd-PEPPSI-IPentCl Precatalyst.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 33, p. 9507, doi. 10.1002/anie.201502822

By:

Sharif, Sepideh;
Rucker, Richard P.;
Chandrasoma, Nalin;
Mitchell, David;
Rodriguez, Michael J.;
Froese, Robert D. J.;
Organ, Michael G.

Publication type:

Article

Frontispiece: The Selective Cross-Coupling of Secondary Alkyl Zinc Reagents to Five-Membered-Ring Heterocycles Using Pd-PEPPSI-IHeptCl.

Published in:

2015

By:

Atwater, Bruce;
Chandrasoma, Nalin;
Mitchell, David;
Rodriguez, Michael J.;
Pompeo, Matthew;
Froese, Robert D. J.;
Organ, Michael G.

Publication type:

Other

The Selective Cross-Coupling of Secondary Alkyl Zinc Reagents to Five-Membered-Ring Heterocycles Using Pd-PEPPSI-IHeptCl.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 33, p. 9502, doi. 10.1002/anie.201503941

By:

Atwater, Bruce;
Chandrasoma, Nalin;
Mitchell, David;
Rodriguez, Michael J.;
Pompeo, Matthew;
Froese, Robert D. J.;
Organ, Michael G.

Publication type:

Article

On The Remarkably Different Role of Salt in the Cross-Coupling of Arylzincs From That Seen With Alkylzincs.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 17, p. 4386, doi. 10.1002/anie.201400459

By:

McCann, Lucas C.;
Organ, Michael G.

Publication type:

Article

Room-Temperature Amination of Deactivated Aniline and Aryl Halide Partners with Carbonate Base Using a Pd-PEPPSI-IPentCl- o-Picoline Catalyst.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 12, p. 3223, doi. 10.1002/anie.201310457

By:

Pompeo, Matthew;
Farmer, Jennifer L.;
Froese, Robert D. J.;
Organ, Michael G.

Publication type:

Article

2,2′-Azobis(2-methylpropionitrile)-Mediated Alkyne Hydrostannylation: Reaction Mechanism.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 43, p. 11334, doi. 10.1002/anie.201303736

By:

Oderinde, Martins S.;
Froese, Robert D. J.;
Organ, Michael G.

Publication type:

Article

Lithium aluminum hydride in flow: overcoming exotherms, solids, and gas evolution en route to chemoselective reductions.

Published in:

Journal of Flow Chemistry, 2022, v. 12, n. 1, p. 131, doi. 10.1007/s41981-021-00201-1

By:

Mohammadzadeh, Aliakbar;
Sharif, Sepideh;
Semeniuchenko, Volodymyr;
Townsend, Norman;
Corbett, Andrew D.;
Organ, Michael G.

Publication type:

Article

Process Analytical Tools for Flow Analysis: A Perspective.

Published in:

Journal of Flow Chemistry, 2017, v. 7, n. 3/4, p. 82, doi. 10.1556/1846.2017.00032

By:

Price, Gregory A.;
Mallik, Debasis;
Organ, Michael G.

Publication type:

Article

A silyl-mediated [3+2] photochemical cycloaddition.

Published in:

Canadian Journal of Chemistry, 2006, v. 84, n. 10, p. 1259, doi. 10.1139/V06-077

By:

Organ, Michael G.;
Mallik, Debasis

Publication type:

Article

Pd-PEPPSI-IPent-SiO2: A Supported Catalyst for Challenging Negishi Coupling Reactions in Flow.

Published in:

Angewandte Chemie, 2017, v. 129, n. 43, p. 13532, doi. 10.1002/ange.201708598

By:

Price, Gregory A.;
Hassan, Abbas;
Chandrasoma, Nalin;
Bogdan, Andrew R.;
Djuric, Stevan W.;
Organ, Michael G.

Publication type:

Article

The Selective Cross-Coupling of Secondary Alkyl Zinc Reagents to Five-Membered-Ring Heterocycles Using Pd-PEPPSI-IHeptCl.

Published in:

Angewandte Chemie, 2015, v. 127, n. 33, p. 9638, doi. 10.1002/ange.201503941

By:

Atwater, Bruce;
Chandrasoma, Nalin;
Mitchell, David;
Rodriguez, Michael J.;
Pompeo, Matthew;
Froese, Robert D. J.;
Organ, Michael G.

Publication type:

Article

Selective Monoarylation of Primary Amines Using the Pd-PEPPSI-IPentCl Precatalyst.

Published in:

Angewandte Chemie, 2015, v. 127, n. 33, p. 9643, doi. 10.1002/ange.201502822

By:

Sharif, Sepideh;
Rucker, Richard P.;
Chandrasoma, Nalin;
Mitchell, David;
Rodriguez, Michael J.;
Froese, Robert D. J.;
Organ, Michael G.

Publication type:

Article

Frontispiz: The Selective Cross-Coupling of Secondary Alkyl Zinc Reagents to Five-Membered-Ring Heterocycles Using Pd-PEPPSI-IHeptCl.

Published in:

2015

By:

Atwater, Bruce;
Chandrasoma, Nalin;
Mitchell, David;
Rodriguez, Michael J.;
Pompeo, Matthew;
Froese, Robert D. J.;
Organ, Michael G.

Publication type:

Other

On The Remarkably Different Role of Salt in the Cross-Coupling of Arylzincs From That Seen With Alkylzincs.

Published in:

Angewandte Chemie, 2014, v. 126, n. 17, p. 4475, doi. 10.1002/ange.201400459

By:

McCann, Lucas C.;
Organ, Michael G.

Publication type:

Article

Room-Temperature Amination of Deactivated Aniline and Aryl Halide Partners with Carbonate Base Using a Pd-PEPPSI-IPentCl- o-Picoline Catalyst.

Published in:

Angewandte Chemie, 2014, v. 126, n. 12, p. 3287, doi. 10.1002/ange.201310457

By:

Pompeo, Matthew;
Farmer, Jennifer L.;
Froese, Robert D. J.;
Organ, Michael G.

Publication type:

Article

Pd-PEPPSI-IPentCl: A Highly Effective Catalyst for the Selective Cross-Coupling of Secondary Organozinc Reagents.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 45, p. 11354, doi. 10.1002/anie.201205747

By:

Pompeo, Matthew;
Froese, Robert D. J.;
Hadei, Niloufar;
Organ, Michael G.

Publication type:

Article

Studies on the Mechanism of B(C6F5)3-Catalyzed Hydrostannylation of Propargylic Alcohol Derivatives.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 39, p. 9834, doi. 10.1002/anie.201204060

By:

Oderinde, Martins S.;
Organ, Michael G.

Publication type:

Article

Higher-Order Zincates as Transmetalators in Alkyl-Alkyl Negishi Cross-Coupling.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 28, p. 7024, doi. 10.1002/anie.201203547

By:

McCann, Lucas C.;
Hunter, Howard N.;
Clyburne, Jason A. C.;
Organ, Michael G.

Publication type:

Article

The Development of Bulky Palladium NHC Complexes for the Most-Challenging Cross-Coupling Reactions.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 14, p. 3314, doi. 10.1002/anie.201106131

By:

Valente, Cory;
Çalimsiz, Selçuk;
Hoi, Ka Hou;
Mallik, Debasis;
Sayah, Mahmoud;
Organ, Michael G.

Publication type:

Article

Differentiating CBr and CCl Bond Activation by Using Solvent Polarity: Applications to Orthogonal Alkyl-Alkyl Negishi Reactions.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 17, p. 3896, doi. 10.1002/anie.201100705

By:

Hadei, Niloufar;
Achonduh, George T.;
Valente, Cory;
O'Brien, Christopher J.;
Organ, Michael G.

Publication type:

Article

Pd-PEPPSI-IPent: Low-Temperature Negishi Cross-Coupling for the Preparation of Highly Functionalized, Tetra- ortho-Substituted Biaryls.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 11, p. 2014, doi. 10.1002/anie.200906811

By:

Çalimsiz, Selçuk;
Sayah, Mahmoud;
Mallik, Debasis;
Organ, Michael G.

Publication type:

Article

Pd-PEPPSI-IPent: An Active, Sterically Demanding Cross-Coupling Catalyst and Its Application in the Synthesis of Tetra- Ortho-Substituted Biaryls.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 13, p. 2383, doi. 10.1002/anie.200805661

By:

Organ, Michael G.;
Çalimsiz, Selçuk;
Sayah, Mahmoud;
Hoi, Ka Hou;
Lough, Alan J.

Publication type:

Article

The preparation of amino-substituted biaryl libraries: The application of solid-supported reagents to streamline solution-phase synthesis.

Published in:

Biotechnology & Bioengineering, 2000, v. 71, n. 1, p. 71, doi. 10.1002/(SICI)1097-0290(200024)71:1<71::AID-BIT10>3.0.CO;2-U

By:

Organ, Michael G.;
Dixon, Craig E.

Publication type:

Article

Kinetic versus Thermodynamic Stereoselectivity in the Hydrostannylation of Propargylic Alcohol Derivatives Using AIBN and Et3B as Promotors.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 35, p. 10817, doi. 10.1002/chem.201202099

By:

Oderinde, Martins S.;
Hunter, Howard N.;
Organ, Michael G.

Publication type:

Article

Highly Stereo- and Regioselective Hydrostannylation of Internal Alkynes Promoted by Simple Boric Acid in Air.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 35, p. 10821, doi. 10.1002/chem.201202100

By:

Oderinde, Martins S.;
Hunter, Howard N.;
Froese, Robert D. J.;
Organ, Michael G.

Publication type:

Article

Potassium 2,2,5,7,8-Pentamethylchroman-6-oxide: A Rationally Designed Base for Pd-Catalysed Amination.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 3, p. 804, doi. 10.1002/chem.201103284

By:

Hoi, Ka Hou;
Organ, Michael G.

Publication type:

Article

Amination with PdNHC Complexes: Rate and Computational Studies Involving Substituted Aniline Substrates.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 1, p. 145, doi. 10.1002/chem.201102428

By:

Hoi, Ka Hou;
Çalimsiz, Selçuk;
Froese, Robert D. J.;
Hopkinson, Alan C.;
Organ, Michael G.

Publication type:

Article

Carbon-Sulfur Bond Formation of Challenging Substrates at Low Temperature by Using Pd-PEPPSI-IPent.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 42, p. 11719, doi. 10.1002/chem.201102158

By:

Sayah, Mahmoud;
Organ, Michael G.

Publication type:

Article

In Situ Generation and Intramolecular Schmidt Reaction of Keto Azides in a Microwave-Assisted Flow Format.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 35, p. 9595, doi. 10.1002/chem.201100768

By:

Painter, Thomas O.;
Thornton, Paul D.;
Orestano, Mario;
Santini, Conrad;
Organ, Michael G.;
Aubé, Jeffrey

Publication type:

Article

Inside Cover: Identification of a Higher-Order Organozincate Intermediate Involved in Negishi Cross-Coupling Reactions by Mass Spectrometry and NMR Spectroscopy (Chem. Eur. J. 28/2011).

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 28, p. 7706, doi. 10.1002/chem.201190141

By:

Hunter, Howard N.;
Hadei, Niloufar;
Blagojevic, Voislav;
Patschinski, Pascal;
Achonduh, George T.;
Avola, Stephanie;
Bohme, Diethard K.;
Organ, Michael G.

Publication type:

Article

Identification of a Higher-Order Organozincate Intermediate Involved in Negishi Cross-Coupling Reactions by Mass Spectrometry and NMR Spectroscopy.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 28, p. 7845, doi. 10.1002/chem.201101029

By:

Hunter, Howard N.;
Hadei, Niloufar;
Blagojevic, Voislav;
Patschinski, Pascal;
Achonduh, George T.;
Avola, Stephanie;
Bohme, Diethard K.;
Organ, Michael G.

Publication type:

Article

Amination with Pd-NHC Complexes: Rate and Computational Studies on the Effects of the Oxidative Addition Partner.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 11, p. 3086, doi. 10.1002/chem.201002988

By:

Hoi, Ka Hou;
Çalimsiz, Selçuk;
Froese, Robert D. J.;
Hopkinson, Alan C.;
Organ, Michael G.

Publication type:

Article

The Development of a General Strategy for the Synthesis of Tyramine-Based Natural Products by Using Continuous Flow Techniques.

Published in:

Chemistry - A European Journal, 2010, v. 16, n. 43, p. 12797, doi. 10.1002/chem.201002102

By:

Achanta, Srinivas;
Liautard, Virginie;
Paugh, Robert;
Organ, Michael G.

Publication type:

Article

Scaling Out by Microwave-Assisted, Continuous Flow Organic Synthesis (MACOS): Multi-Gram Synthesis of Bromo- and Fluoro-benzofused Sultams Benzthiaoxazepine-1,1-dioxides.

Published in:

Chemistry - A European Journal, 2010, v. 16, n. 36, p. 10959, doi. 10.1002/chem.201001651

By:

Ullah, Farman;
Samarakoon, Thiwanka;
Rolfe, Alan;
Kurtz, Ryan D.;
Hanson, Paul R.;
Organ, Michael G.

Publication type:

Article

Structure-Activity Relationship Analysis of Pd-PEPPSI Complexes in Cross-Couplings: A Close Inspection of the Catalytic Cycle and the Precatalyst Activation Model.

Published in:

Chemistry - A European Journal, 2010, v. 16, n. 35, p. 10844, doi. 10.1002/chem.201000138

By:

Nasielski, Joanna;
Hadei, Nilofaur;
Achonduh, George;
Kantchev, Eric Assen B.;
O'Brien, Christopher J.;
Lough, Alan;
Organ, Michael G.

Publication type:

Article