Works by Orekhov, Alexander N.

Results: 215

The role of NRF2 function and regulation in atherosclerosis: an update.

Published in:

Molecular & Cellular Biochemistry, 2025, v. 480, n. 7, p. 3935, doi. 10.1007/s11010-025-05233-y

By:

Dabravolski, Siarhei A.;
Churov, Alexey V.;
Beloyartsev, Dmitry F.;
Kovyanova, Tatiana I.;
Lyapina, Irina N.;
Sukhorukov, Vasily N.;
Orekhov, Alexander N.

Publication type:

Article

Exploring Neutrophil Extracellular Traps in Cardiovascular Pathologies: The Impact of Lipid Profiles, PAD4, and Radiation.

Published in:

Biocell, 2025, v. 49, n. 6, p. 931, doi. 10.32604/biocell.2025.062789

By:

Dabravolski, Siarhei A.;
Bukrinsky, Michael I.;
Utkina, Aleksandra S.;
Ravani, Alessio L.;
Sukhorukov, Vasily N.;
Orekhov, Alexander N.

Publication type:

Article

The association of TNF-alpha secretion and mtDNA copy number in CD14<sup>+</sup> monocytes of patients with obesity and CHD.

Published in:

Frontiers in Molecular Biosciences, 2024, p. 1, doi. 10.3389/fmolb.2024.1362955

By:

Tolstik, Taisiya V.;
Kirichenko, Tatiana V.;
Markin, Alexander M.;
Bogatyreva, Anastasia I.;
Markina, Yuliya V.;
Kiseleva, Diana G.;
Shaposhnikova, Nataliya N.;
Starodubova, Antonina V.;
Orekhov, Alexander N.

Publication type:

Article

Possible Role of Mitochondrial DNA Mutations in Chronification of Inflammation: Focus on Atherosclerosis.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 4, p. 978, doi. 10.3390/jcm9040978

By:

Orekhov, Alexander N.;
Nikiforov, Nikita N.;
Ivanova, Ekaterina A.;
Sobenin, Igor A.

Publication type:

Article

Immune-Inflammatory Responses in Atherosclerosis: The Role of Myeloid Cells.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 11, p. 1798, doi. 10.3390/jcm8111798

By:

Chistiakov, Dimitry A.;
Kashirskikh, Dmitry A.;
Khotina, Victoriya A.;
Grechko, Andrey V.;
Orekhov, Alexander N.

Publication type:

Article

Mitochondrial Dysfunction in Systemic Lupus Erythematosus: Insights and Therapeutic Potential.

Published in:

Diseases, 2024, v. 12, n. 9, p. 226, doi. 10.3390/diseases12090226

By:

Poznyak, Anastasia V.;
Orekhov, Nikolay A.;
Churov, Alexey V.;
Starodubtseva, Irina A.;
Beloyartsev, Dmitry F.;
Kovyanova, Tatiana I.;
Sukhorukov, Vasily N.;
Orekhov, Alexander N.

Publication type:

Article

Target Role of Monocytes as Key Cells of Innate Immunity in Rheumatoid Arthritis.

Published in:

Diseases, 2024, v. 12, n. 5, p. 81, doi. 10.3390/diseases12050081

By:

Salnikova, Diana I.;
Nikiforov, Nikita G.;
Postnov, Anton Y.;
Orekhov, Alexander N.

Publication type:

Article

Involvement of Oxidative Stress and the Innate Immune System in SARS-CoV-2 Infection.

Published in:

Diseases, 2021, v. 9, n. 1, p. 17, doi. 10.3390/diseases9010017

By:

Kozlov, Evgenii M.;
Ivanova, Ekaterina;
Grechko, Andrey V.;
Wu, Wei-Kai;
Starodubova, Antonina V.;
Orekhov, Alexander N.;
Monroy, Fernando

Publication type:

Article

The Interaction of Plasma Sialylated and Desialylated Lipoproteins with Collagen fromthe Intima andMedia of Uninvolved and Atherosclerotic Human Aorta.

Published in:

Journal of Lipids, 2011, p. 1, doi. 10.1155/2011/254267

By:

Sobenin, Igor A.;
Suprun, Igor V.;
Karagodin, Vasiliy P.;
Feoktistov, Alexander S.;
Melnichenko, Alexandra A.;
Orekhov, Alexander N.

Publication type:

Article

Decreased Expression of Liver X Receptor-α in Macrophages Infected with Chlamydia pneumoniae in Human Atherosclerotic Arteries in situ.

Published in:

Journal of Innate Immunity, 2011, v. 3, n. 5, p. 483, doi. 10.1159/000327522

By:

Bobryshev, Yuri V.;
Orekhov, Alexander N.;
Killingsworth, Murray C.;
Lu, Jinhua

Publication type:

Article

Response to: Comment on “Role of Mitochondrial Genome Mutations in Pathogenesis of Carotid Atherosclerosis”.

Published in:

Oxidative Medicine & Cellular Longevity, 2018, p. 1, doi. 10.1155/2018/7620234

By:

Sobenin, Igor A.;
Sazonova, Margarita A.;
Sinyov, Vasily V.;
Ryzhkova, Anastasia I.;
Galitsyna, Elena V.;
Khasanova, Zukhra B.;
Postnov, Anton Y.;
Yarygina, Elena I.;
Shkurat, Tatiana P.;
Orekhov, Alexander N.

Publication type:

Article

Cybrid Models of Pathological Cell Processes in Different Diseases.

Published in:

Oxidative Medicine & Cellular Longevity, 2018, p. 1, doi. 10.1155/2018/4647214

By:

Sazonova, Margarita A.;
Sinyov, Vasily V.;
Ryzhkova, Anastasia I.;
Galitsyna, Elena V.;
Melnichenko, Alexandra A.;
Postnov, Anton Y.;
Orekhov, Alexander N.;
Sobenin, Igor A.

Publication type:

Article

Necroptosis in myocardial ischaemia-reperfusion injury: current update on mechanisms, therapeutic targets, and translational potential.

Published in:

Apoptosis, 2025, v. 30, n. 5, p. 1216, doi. 10.1007/s10495-025-02108-x

By:

Dabravolski, Siarhei A.;
Kalmykov, Vladislav A.;
Maksaeva, Anastasia O.;
Rozhkova, Ulyana V.;
Lapshina, Ksenia O.;
Orekhov, Alexander N.

Publication type:

Article

Rheumatoid Arthritis: What Inflammation Do We Face?

Published in:

Journal of Molecular Pathology, 2024, v. 5, n. 4, p. 454, doi. 10.3390/jmp5040030

By:

Poznyak, Anastasia V.;
Kirichenko, Tatyana Vladimirovna;
Beloyartsev, Dmitry Felixovich;
Churov, Alexey V.;
Kovyanova, Tatiana Ivanovna;
Starodubtseva, Irina Alexandrovna;
Sukhorukov, Vasily N.;
Antonov, Stanislav A.;
Orekhov, Alexander N.

Publication type:

Article

Role of Cathelicidins in Atherosclerosis and Associated Cardiovascular Diseases.

Published in:

Journal of Molecular Pathology, 2024, v. 5, n. 3, p. 319, doi. 10.3390/jmp5030023

By:

Dabravolski, Siarhei A.;
Orekhov, Nikolay A.;
Churov, Alexey V.;
Starodubtseva, Irina A.;
Beloyartsev, Dmitry F.;
Kovyanova, Tatiana I.;
Sukhorukov, Vasily N.;
Orekhov, Alexander N.

Publication type:

Article

Association between atherosclerosis and the development of multi-organ pathologies.

Published in:

SAGE Open Medicine, 2024, p. 1, doi. 10.1177/20503121241310013

By:

Dabravolski, Siarhei A;
Churov, Alexey V;
Elizova, Natalia V;
Ravani, Alessio L;
Karimova, Amina E;
Sukhorukov, Vasily N;
Orekhov, Alexander N

Publication type:

Article

Long Non-Coding RNAs in Colorectal Cancer: Navigating the Intersections of Immunity, Intercellular Communication, and Therapeutic Potential.

Published in:

Biomedicines, 2023, v. 11, n. 9, p. 2411, doi. 10.3390/biomedicines11092411

By:

Shakhpazyan, Nikolay K.;
Mikhaleva, Liudmila M.;
Bedzhanyan, Arcady L.;
Sadykhov, Nikolay K.;
Midiber, Konstantin Y.;
Konyukova, Alexandra K.;
Kontorschikov, Andrey S.;
Maslenkina, Ksenia S.;
Orekhov, Alexander N.

Publication type:

Article

Is There a Relationship between Adverse Pregnancy Outcomes and Future Development of Atherosclerosis?

Published in:

Biomedicines, 2023, v. 11, n. 9, p. 2430, doi. 10.3390/biomedicines11092430

By:

Poznyak, Anastasia V.;
Khotina, Victoria A.;
Zhigmitova, Elena B.;
Sukhorukov, Vasily N.;
Postnov, Anton Y.;
Orekhov, Alexander N.

Publication type:

Article

The Role of Selenium in Atherosclerosis Development, Progression, Prevention and Treatment.

Published in:

Biomedicines, 2023, v. 11, n. 7, p. 2010, doi. 10.3390/biomedicines11072010

By:

Dabravolski, Siarhei A.;
Sukhorukov, Vasily N.;
Melnichenko, Alexandra A.;
Khotina, Victoria A.;
Orekhov, Alexander N.

Publication type:

Article

HDL-Based Therapy: Vascular Protection at All Stages.

Published in:

Biomedicines, 2023, v. 11, n. 3, p. 711, doi. 10.3390/biomedicines11030711

By:

Poznyak, Anastasia V.;
Sukhorukov, Vasily N.;
Eremin, Ilya I.;
Nadelyaeva, Irina I.;
Gutyrchik, Nikita A.;
Orekhov, Alexander N.

Publication type:

Article

The Role of Pericytes in Regulation of Innate and Adaptive Immunity.

Published in:

Biomedicines, 2023, v. 11, n. 2, p. 600, doi. 10.3390/biomedicines11020600

By:

Dabravolski, Siarhei A.;
Andreeva, Elena R.;
Eremin, Ilya I.;
Markin, Alexander M.;
Nadelyaeva, Irina I.;
Orekhov, Alexander N.;
Melnichenko, Alexandra A.

Publication type:

Article

Creation of Mitochondrial Disease Models Using Mitochondrial DNA Editing.

Published in:

Biomedicines, 2023, v. 11, n. 2, p. 532, doi. 10.3390/biomedicines11020532

By:

Khotina, Victoria A.;
Vinokurov, Andrey Y.;
Bagheri Ekta, Mariam;
Sukhorukov, Vasily N.;
Orekhov, Alexander N.

Publication type:

Article

Proprotein Convertase Subtilisin/Kexin 9 as a Modifier of Lipid Metabolism in Atherosclerosis.

Published in:

Biomedicines, 2023, v. 11, n. 2, p. 503, doi. 10.3390/biomedicines11020503

By:

Poznyak, Anastasia V.;
Sukhorukov, Vasily N.;
Eremin, Ilya I.;
Nadelyaeva, Irina I.;
Gutyrchik, Nikita A.;
Orekhov, Alexander N.

Publication type:

Article

Familial Hypercholesterolaemia as a Predisposing Factor for Atherosclerosis.

Published in:

Biomedicines, 2022, v. 10, n. 10, p. N.PAG, doi. 10.3390/biomedicines10102639

By:

Poznyak, Anastasia V.;
Litvinova, Larisa;
Poggio, Paolo;
Orekhov, Alexander N.;
Melnichenko, Alexandra A.

Publication type:

Article

Atherosclerosis Specific Features in Chronic Kidney Disease (CKD).

Published in:

Biomedicines, 2022, v. 10, n. 9, p. 2094, doi. 10.3390/biomedicines10092094

By:

Poznyak, Anastasia V.;
Sadykhov, Nikolay K.;
Kartuesov, Andrey G.;
Borisov, Evgeny E.;
Sukhorukov, Vasily N.;
Orekhov, Alexander N.

Publication type:

Article

Macrophages in Health and Non-Infectious Disease 2.0.

Published in:

Biomedicines, 2022, v. 10, n. 6, p. 1215, doi. 10.3390/biomedicines10061215

By:

Bezsonov, Evgeny E.;
Gratchev, Alexei;
Orekhov, Alexander N.

Publication type:

Article

Thirty-Five-Year History of Desialylated Lipoproteins Discovered by Vladimir Tertov.

Published in:

Biomedicines, 2022, v. 10, n. 5, p. 1174, doi. 10.3390/biomedicines10051174

By:

Glanz, Victor;
Bezsonov, Evgeny E.;
Soldatov, Vladislav;
Orekhov, Alexander N.

Publication type:

Article

Somatic Mutations of Hematopoietic Cells Are an Additional Mechanism of Body Aging, Conducive to Comorbidity and Increasing Chronification of Inflammation.

Published in:

Biomedicines, 2022, v. 10, n. 4, p. 782, doi. 10.3390/biomedicines10040782

By:

Yegorov, Yegor E.;
Poznyak, Anastasia V.;
Bezsonov, Evgeny E.;
Zhuravlev, Alexander D.;
Nikiforov, Nikita G.;
Vishnyakova, Khava S.;
Orekhov, Alexander N.

Publication type:

Article

Functional Phenotypes of Intraplaque Macrophages and Their Distinct Roles in Atherosclerosis Development and Atheroinflammation.

Published in:

Biomedicines, 2022, v. 10, n. 2, p. 452, doi. 10.3390/biomedicines10020452

By:

Mushenkova, Nataliya V.;
Nikiforov, Nikita G.;
Melnichenko, Alexandra A.;
Kalmykov, Vladislav;
Shakhpazyan, Nikolay K.;
Orekhova, Varvara A.;
Orekhov, Alexander N.

Publication type:

Article

The Role of KLF2 in the Regulation of Atherosclerosis Development and Potential Use of KLF2-Targeted Therapy.

Published in:

Biomedicines, 2022, v. 10, n. 2, p. 254, doi. 10.3390/biomedicines10020254

By:

Dabravolski, Siarhei A.;
Sukhorukov, Vasily N.;
Kalmykov, Vladislav A.;
Grechko, Andrey V.;
Shakhpazyan, Nikolay K.;
Orekhov, Alexander N.

Publication type:

Article

Lipids and Lipoproteins in Health and Disease.

Published in:

Biomedicines, 2022, v. 10, n. 1, p. 87, doi. 10.3390/biomedicines10010087

By:

Bezsonov, Evgeny E.;
Sobenin, Igor A.;
Orekhov, Alexander N.

Publication type:

Article

Macrophages and Foam Cells: Brief Overview of Their Role, Linkage, and Targeting Potential in Atherosclerosis.

Published in:

Biomedicines, 2021, v. 9, n. 9, p. 1221, doi. 10.3390/biomedicines9091221

By:

Poznyak, Anastasia V.;
Nikiforov, Nikita G.;
Starodubova, Antonina V.;
Popkova, Tatyana V.;
Orekhov, Alexander N.

Publication type:

Article

Recognition of Oxidized Lipids by Macrophages and Its Role in Atherosclerosis Development.

Published in:

Biomedicines, 2021, v. 9, n. 8, p. 915, doi. 10.3390/biomedicines9080915

By:

Mushenkova, Nataliya V.;
Bezsonov, Evgeny E.;
Orekhova, Varvara A.;
Popkova, Tatyana V.;
Starodubova, Antonina V.;
Orekhov, Alexander N.

Publication type:

Article

Effect of Oxidized Low-Density Lipoprotein on Head and Neck Squamous Cell Carcinomas.

Published in:

Biomedicines, 2021, v. 9, n. 5, p. 513, doi. 10.3390/biomedicines9050513

By:

Kindt, Nadège;
Journé, Fabrice;
Carlier, Stéphane;
Trelcat, Anne;
Scalia, Alessandro;
Saussez, Sven;
Orekhov, Alexander N.;
Sobenin, Igor A.

Publication type:

Article

The Susceptibility to Diet-Induced Atherosclerosis Is Exacerbated with Aging in C57B1/6 Mice.

Published in:

Biomedicines, 2021, v. 9, n. 5, p. 487, doi. 10.3390/biomedicines9050487

By:

Simo, Olivier Kamtchueng;
Berrougui, Hicham;
Fulop, Tamas;
Khalil, Abdelouahed;
Orekhov, Alexander N.;
Sobenin, Igor A.

Publication type:

Article

Carnosine Protects Macrophages against the Toxicity of Aβ1-42 Oligomers by Decreasing Oxidative Stress.

Published in:

Biomedicines, 2021, v. 9, n. 5, p. 477, doi. 10.3390/biomedicines9050477

By:

Caruso, Giuseppe;
Benatti, Cristina;
Musso, Nicolò;
Fresta, Claudia G.;
Fidilio, Annamaria;
Spampinato, Giorgia;
Brunello, Nicoletta;
Bucolo, Claudio;
Drago, Filippo;
Lunte, Susan M.;
Peterson, Blake R.;
Tascedda, Fabio;
Caraci, Filippo;
Orekhov, Alexander N.

Publication type:

Article

Anti-Atherosclerotic Potential of Free Fatty Acid Receptor 4 (FFAR4).

Published in:

Biomedicines, 2021, v. 9, n. 5, p. 467, doi. 10.3390/biomedicines9050467

By:

Kiepura, Anna;
Stachyra, Kamila;
Olszanecki, Rafał;
Orekhov, Alexander N.

Publication type:

Article

Association between Vitamin D Deficiency and High Serum Levels of Small Dense LDL in Middle-Aged Adults.

Published in:

Biomedicines, 2021, v. 9, n. 5, p. 464, doi. 10.3390/biomedicines9050464

By:

Han, Yin-Yi;
Hsu, Sandy Huey-Jen;
Su, Ta-Chen;
Orekhov, Alexander N.;
Sobenin, Igor A.

Publication type:

Article

Macrophages in Health and Non-Infectious Disease.

Published in:

2021

By:

Bezsonov, Evgeny E.;
Gratchev, Alexei;
Orekhov, Alexander N.

Publication type:

Editorial

Characterization of Differentially Expressed Circulating miRNAs in Metabolically Healthy versus Unhealthy Obesity.

Published in:

Biomedicines, 2021, v. 9, n. 3, p. 321, doi. 10.3390/biomedicines9030321

By:

Rovira-Llopis, Susana;
Díaz-Rúa, Rubén;
Grau-del Valle, Carmen;
Iannantuoni, Francesca;
Abad-Jimenez, Zaida;
Bosch-Sierra, Neus;
Panadero-Romero, Joaquín;
Victor, Víctor M.;
Rocha, Milagros;
Morillas, Carlos;
Bañuls, Celia;
Orekhov, Alexander N.;
Sobenin, Igor A.

Publication type:

Article

From Mitochondria to Atherosclerosis: The Inflammation Path.

Published in:

Biomedicines, 2021, v. 9, n. 3, p. 258, doi. 10.3390/biomedicines9030258

By:

Suárez-Rivero, Juan M.;
Pastor-Maldonado, Carmen J.;
Povea-Cabello, Suleva;
Álvarez-Córdoba, Mónica;
Villalón-García, Irene;
Talaverón-Rey, Marta;
Suárez-Carrillo, Alejandra;
Munuera-Cabeza, Manuel;
Sánchez-Alcázar, José A.;
Orekhov, Alexander N.

Publication type:

Article

Obesity Affects HDL Metabolism, Composition and Subclass Distribution.

Published in:

Biomedicines, 2021, v. 9, n. 3, p. 242, doi. 10.3390/biomedicines9030242

By:

Stadler, Julia T.;
Lackner, Sonja;
Mörkl, Sabrina;
Trakaki, Athina;
Scharnagl, Hubert;
Borenich, Andrea;
Wonisch, Willibald;
Mangge, Harald;
Zelzer, Sieglinde;
Meier-Allard, Nathalie;
Holasek, Sandra J.;
Marsche, Gunther;
Orekhov, Alexander N.;
Sobenin, Igor A.

Publication type:

Article

Vitamin D and Its Role in the Lipid Metabolism and the Development of Atherosclerosis.

Published in:

Biomedicines, 2021, v. 9, n. 2, p. 172, doi. 10.3390/biomedicines9020172

By:

Surdu, Andrei Mihai;
Pînzariu, Oana;
Ciobanu, Dana-Mihaela;
Negru, Alina-Gabriela;
Căinap, Simona-Sorana;
Lazea, Cecilia;
Iacob, Daniela;
Săraci, George;
Tirinescu, Dacian;
Borda, Ileana Monica;
Cismaru, Gabriel;
Orekhov, Alexander N.

Publication type:

Article

Netrin-1 in Atherosclerosis: Relationship between Human Macrophage Intracellular Levels and In Vivo Plaque Morphology.

Published in:

Biomedicines, 2021, v. 9, n. 2, p. 168, doi. 10.3390/biomedicines9020168

By:

Fiorelli, Susanna;
Cosentino, Nicola;
Porro, Benedetta;
Fabbiocchi, Franco;
Niccoli, Giampaolo;
Fracassi, Francesco;
Capra, Nicolò;
Barbieri, Simone;
Crea, Filippo;
Marenzi, Giancarlo;
Cavalca, Viviana;
Tremoli, Elena;
Eligini, Sonia;
Gratchev, Alexei;
Orekhov, Alexander N.

Publication type:

Article

Two Subpopulations of Human Monocytes That Differ by Mitochondrial Membrane Potential.

Published in:

Biomedicines, 2021, v. 9, n. 2, p. 153, doi. 10.3390/biomedicines9020153

By:

Nikiforov, Nikita G.;
Ryabova, Anastasia;
Kubekina, Marina V.;
Romanishkin, Igor D.;
Trofimov, Kirill A.;
Chegodaev, Yegor S.;
Ivanova, Ekaterina;
Orekhov, Alexander N.;
Jeon, Byeong Hwa

Publication type:

Article

Lipid Metabolism in Macrophages: Focus on Atherosclerosis.

Published in:

Biomedicines, 2020, v. 8, n. 8, p. 262, doi. 10.3390/biomedicines8080262

By:

Sukhorukov, Vasily N.;
Khotina, Victoria A.;
Chegodaev, Yegor S.;
Ivanova, Ekaterina;
Sobenin, Igor A.;
Orekhov, Alexander N.

Publication type:

Article

Endoplasmic Reticulum Stress in Macrophages: The Vicious Circle of Lipid Accumulation and Pro-Inflammatory Response.

Published in:

Biomedicines, 2020, v. 8, n. 7, p. 210, doi. 10.3390/biomedicines8070210

By:

Sukhorukov, Vasily N.;
Khotina, Victoria A.;
Bagheri Ekta, Mariam;
Ivanova, Ekaterina A.;
Sobenin, Igor A.;
Orekhov, Alexander N.

Publication type:

Article

NADPH Oxidases and Their Role in Atherosclerosis.

Published in:

Biomedicines, 2020, v. 8, n. 7, p. 206, doi. 10.3390/biomedicines8070206

By:

Poznyak, Anastasia V.;
Grechko, Andrey V.;
Orekhova, Varvara A.;
Khotina, Victoria;
Ivanova, Ekaterina A.;
Orekhov, Alexander N.

Publication type:

Article

NLPR3 Inflammasomes and Their Significance for Atherosclerosis.

Published in:

Biomedicines, 2020, v. 8, n. 7, p. 205, doi. 10.3390/biomedicines8070205

By:

Poznyak, Anastasia V.;
Melnichenko, Alexandra A.;
Wetzker, Reinhard;
Gerasimova, Elena V.;
Orekhov, Alexander N.

Publication type:

Article

The Link between Chronic Stress and Accelerated Aging.

Published in:

Biomedicines, 2020, v. 8, n. 7, p. 198, doi. 10.3390/biomedicines8070198

By:

Yegorov, Yegor E.;
Poznyak, Anastasia V.;
Nikiforov, Nikita G.;
Sobenin, Igor A.;
Orekhov, Alexander N.

Publication type:

Article