Works matching AU Onishi, Hideya

Results: 41

Immunological analysis of hybrid neoantigen peptide encompassing class I/II neoepitope-pulsed dendritic cell vaccine.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1223331

By:

Shinji Morisaki;
Hideya Onishi;
Takafumi Morisaki;
Makoto Kubo;
Masayo Umebayashi;
Hiroto Tanaka;
Norihiro Koya;
Shinichiro Nakagawa;
Kenta Tsujimura;
Sachiko Yoshimura;
Poh Yin Yew;
Kazuma Kiyotani;
Yusuke Nakamura;
Masafumi Nakamura;
Takanari Kitazono;
Takashi Morisaki

Publication type:

Article

Cancer therapy that targets the Hedgehog signaling pathway considering the cancer microenvironment (Review).

Published in:

Oncology Reports, 2022, v. 47, n. 5, p. 1, doi. 10.3892/or.2022.8304

By:

HIDEYA ONISHI;
KATSUYA NAKAMURA;
KOSUKE YANAI;
SHUNTARO NAGAI;
KAZUNORI NAKAYAMA;
YASUHIRO OYAMA;
AKIKO FUJIMURA;
KEIGO OZONO;
AKIO YAMASAKI

Publication type:

Article

GLI2 but not GLI1/GLI3 plays a central role in the induction of malignant phenotype of gallbladder cancer.

Published in:

Oncology Reports, 2021, v. 45, n. 3, p. 997, doi. 10.3892/or.2021.7947

By:

Ichimiya, Shu;
Onishi, Hideya;
Nagao, Shinjiro;
Koga, Satoko;
Sakihama, Kukiko;
Nakayama, Kazunori;
Fujimura, Akiko;
Oyama, Yasuhiro;
Imaizumi, Akira;
Oda, Yoshinao;
Nakamura, Masafumi

Publication type:

Article

Reoxygenation from chronic hypoxia promotes metastatic processes in pancreatic cancer through the Hedgehog signaling.

Published in:

Cancer Science, 2014, v. 105, n. 3, p. 324, doi. 10.1111/cas.12348

By:

Morifuji, Yoshihiro;
Onishi, Hideya;
Iwasaki, Hironori;
Imaizumi, Akira;
Nakano, Kenji;
Tanaka, Masao;
Katano, Mitsuo

Publication type:

Article

Hedgehog signaling pathway is a potential therapeutic target for gallbladder cancer.

Published in:

Cancer Science, 2014, v. 105, n. 3, p. 272, doi. 10.1111/cas.12354

By:

Matsushita, Shojiro;
Onishi, Hideya;
Nakano, Kenji;
Nagamatsu, Iori;
Imaizumi, Akira;
Hattori, Masami;
Oda, Yoshinao;
Tanaka, Masao;
Katano, Mitsuo

Publication type:

Article

Hedgehog pathway as a therapeutic target for gallbladder cancer. Immunohistochemical staining for Gli1 in gallbladder cancer.

Published in:

2014

By:

Matsushita, Shojiro;
Onishi, Hideya;
Nakano, Kenji;
Nagamatsu, Iori;
Imaizumi, Akira;
Hattori, Masami;
Oda, Yoshinao;
Tanaka, Masao;
Katano, Mitsuo

Publication type:

Other

Hedgehog Gli3 activator signal augments tumorigenicity of colorectal cancer via upregulation of adherence-related genes.

Published in:

Cancer Science, 2013, v. 104, n. 3, p. 328, doi. 10.1111/cas.12073

By:

Iwasaki, Hironori;
Nakano, Kenji;
Shinkai, Kentaro;
Kunisawa, Yumi;
Hirahashi, Minako;
Oda, Yoshinao;
Onishi, Hideya;
Katano, Mitsuo

Publication type:

Article

Hedgehog inhibitor decreases chemosensitivity to 5-fluorouracil and gemcitabine under hypoxic conditions in pancreatic cancer.

Published in:

Cancer Science, 2012, v. 103, n. 7, p. 1272, doi. 10.1111/j.1349-7006.2012.02297.x

By:

Onishi, Hideya;
Morifuji, Yoshihiro;
Kai, Masaya;
Suyama, Kumi;
Iwasaki, Hironori;
Katano, Mitsuo

Publication type:

Article

Semi-quantitative evaluation of CD44+/CD24− tumor cell distribution in breast cancer tissue using a newly developed fluorescence immunohistochemical staining method.

Published in:

Cancer Science, 2011, v. 102, n. 12, p. Dec cover, doi. 10.1111/j.1349-7006.2011.02063.x

By:

Kai, Masaya;
Onishi, Hideya;
Souzaki, Masae;
Tanaka, Haruo;
Kubo, Makoto;
Tanaka, Masao;
Katano, Mitsuo

Publication type:

Article

Semi-quantitative evaluation of CD44+/CD24− tumor cell distribution in breast cancer tissue using a newly developed fluorescence immunohistochemical staining method.

Published in:

Cancer Science, 2011, v. 102, n. 12, p. 2132, doi. 10.1111/j.1349-7006.2011.02063.x

By:

Kai, Masaya;
Onishi, Hideya;
Souzaki, Masae;
Tanaka, Haruo;
Kubo, Makoto;
Tanaka, Masao;
Katano, Mitsuo

Publication type:

Article

Hedgehog signaling pathway as a therapeutic target in various types of cancer.

Published in:

Cancer Science, 2011, v. 102, n. 10, p. 1756, doi. 10.1111/j.1349-7006.2011.02010.x

By:

Hideya Onishi;
Mitsuo Katano

Publication type:

Article

Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer.

Published in:

Cancer Science, 2011, v. 102, n. 6, p. 1144, doi. 10.1111/j.1349-7006.2011.01912.x

By:

Onishi, Hideya;
Kai, Masaya;
Odate, Seiichi;
Iwasaki, Hironori;
Morifuji, Yoshihiro;
Ogino, Toshitatsu;
Morisaki, Takafumi;
Nakashima, Yutaka;
Katano, Mitsuo

Publication type:

Article

Hedgehog signaling pathway mediates the progression of non-invasive breast cancer to invasive breast cancer.

Published in:

Cancer Science, 2011, v. 102, n. 2, p. 373, doi. 10.1111/j.1349-7006.2010.01779.x

By:

Souzaki, Masae;
Kubo, Makoto;
Kai, Masaya;
Kameda, Chizu;
Tanaka, Haruo;
Taguchi, Tomoaki;
Tanaka, Masao;
Onishi, Hideya;
Katano, Mitsuo

Publication type:

Article

Modulation of allograft immune responses by Porphyromonas gingivalis lipopolysaccharide administration in a rat model of kidney transplantation.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-64771-5

By:

Sato, Yu;
Noguchi, Hiroshi;
Kubo, Shinsuke;
Kaku, Keizo;
Okabe, Yasuhiro;
Onishi, Hideya;
Nakamura, Masafumi

Publication type:

Article

C4orf47 contributes to the dormancy of pancreatic cancer under hypoxic conditions.

Published in:

Journal of Cancer, 2023, v. 14, n. 2, p. 306, doi. 10.7150/jca.78993

By:

Shinjiro Nagao;
Hideya Onishi;
Makoto Kawamoto;
Shogo Masuda;
Lin Na;
Shinji Morisaki;
Naoya Iwamoto;
Yutaka Yamada;
Satoko Koga;
Shu Ichimiya;
Kazunori Nakayama;
Akira Imaizumi;
Kinichi Nakashima;
Yoshinao Oda;
Masafumi Nakamura

Publication type:

Article

Effects of periodontal pathogen-induced intestinal dysbiosis on transplant immunity in an allogenic skin graft model.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-27861-4

By:

Mei, Takanori;
Noguchi, Hiroshi;
Kuraji, Ryutaro;
Kubo, Shinsuke;
Sato, Yu;
Kaku, Keizo;
Okabe, Yasuhiro;
Onishi, Hideya;
Nakamura, Masafumi

Publication type:

Article

Objective response with lapatinib in patients with meningitis carcinomatosa derived from HER2/HER1-negative breast cancer.

Published in:

International Journal of Clinical Oncology, 2011, v. 16, n. 6, p. 718, doi. 10.1007/s10147-011-0195-5

By:

Onishi, Hideya;
Morisaki, Takashi;
Nakafusa, Yuji;
Nakashima, Yutaka;
Yokohata, Kazunori;
Katano, Mitsuo

Publication type:

Article

Contribution of pre-existing neoantigen-specific T cells to a durable complete response after tumor-pulsed dendritic cell vaccine plus nivolumab therapy in a patient with metastatic salivary duct carcinoma.

Published in:

Immunological Investigations, 2022, v. 51, n. 5, p. 1498, doi. 10.1080/08820139.2021.1973491

By:

Ichimiya, Shu;
Fujimura, Akiko;
Masuda, Muneyuki;
Masuda, Shogo;
Yasumatsu, Ryuji;
Umebayashi, Masayo;
Tanaka, Hiroto;
Koya, Norihiro;
Nakagawa, Shinichiro;
Yew, Poh Yin;
Yoshimura, Sachiko;
Onishi, Hideya;
Nakamura, Masafumi;
Nakamura, Yusuke;
Morisaki, Takashi

Publication type:

Article

Intranodal Administration of Neoantigen Peptide-loaded Dendritic Cell Vaccine Elicits Epitope-specific T Cell Responses and Clinical Effects in a Patient with Chemorefractory Ovarian Cancer with Malignant Ascites.

Published in:

Immunological Investigations, 2021, v. 50, n. 5, p. 562, doi. 10.1080/08820139.2020.1778721

By:

Morisaki, Takashi;
Hikichi, Tetsuro;
Onishi, Hideya;
Morisaki, Takafumi;
Kubo, Makoto;
Hirano, Tatsuya;
Yoshimura, Sachiko;
Kiyotani, Kazuma;
Nakamura, Yusuke

Publication type:

Article

A LARGE QUANTITY OF CD3- /CD19- /CD16- LYMPHOCYTES IN MALIGNANT PLEURAL EFFUSION FROM A PATIENT WITH RECURRENT CHOLANGIO CELL CARCINOMA.

Published in:

Immunological Investigations, 2002, v. 31, n. 2, p. 121, doi. 10.1081/IMM-120004803

By:

Onishi, Hideya;
Morisaki, Takashi;
Kuga, Hirotaka;
Katano, Mitsuo;
Doi, Fukashi;
Uchiyama, Akihiko;
Sugitani, Atsushi;
Wada, Junji;
Chijiiwa, Kazuo;
Tanaka, Masao

Publication type:

Article

Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway.

Published in:

Journal of Surgical Oncology, 2009, v. 100, n. 8, p. 725, doi. 10.1002/jso.21392

By:

Ikebe, Mio;
Kitaura, Yoshiki;
Nakamura, Masafumi;
Tanaka, Haruo;
Yamasaki, Akio;
Nagai, Shuntaro;
Wada, Junji;
Yanai, Kosuke;
Koga, Kenichiro;
Sato, Norihiro;
Kubo, Makoto;
Tanaka, Masao;
Onishi, Hideya;
Katano, Mitsuo

Publication type:

Article

PTPN3 inhibition contributes to the activation of the dendritic cell function to be a promising new immunotherapy target.

Published in:

Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 16, p. 14619, doi. 10.1007/s00432-023-05250-8

By:

Iwamoto, Naoya;
Onishi, Hideya;
Masuda, Shogo;
Imaizumi, Akira;
Sakanashi, Keita;
Morisaki, Shinji;
Nagao, Shinjiro;
Koga, Satoko;
Ozono, Keigo;
Umebayashi, Masayo;
Morisaki, Takashi;
Nakamura, Masafumi

Publication type:

Article

Dendritic cell-derived exosomes induce monocyte antigen-presentation and immune amplification in neoantigen vaccine therapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1565696

By:

Morisaki, Shinji;
Onishi, Hideya;
Morisaki, Takafumi;
Kubo, Makoto;
Umebayashi, Masayo;
Tanaka, Hiroto;
Koya, Norihiro;
Nakagawa, Shinichiro;
Tsujimura, Kenta;
Yoshimura, Sachiko;
Yew, Poh Yin;
Kiyotani, Kazuma;
Nakamura, Yusuke;
Nakamura, Masafumi;
Torisu, Takehiro;
Kitazono, Takanari;
Morisaki, Takashi

Publication type:

Article

PTPN3 expressed in activated T lymphocytes is a candidate for a non-antibody-type immune checkpoint inhibitor.

Published in:

Cancer Immunology, Immunotherapy, 2019, v. 68, n. 10, p. 1649, doi. 10.1007/s00262-019-02403-y

By:

Fujimura, Akiko;
Nakayama, Kazunori;
Imaizumi, Akira;
Kawamoto, Makoto;
Oyama, Yasuhiro;
Ichimiya, Shu;
Umebayashi, Masayo;
Koya, Norihiro;
Morisaki, Takashi;
Nakagawa, Takashi;
Onishi, Hideya

Publication type:

Article

The Hedgehog inhibitor cyclopamine impairs the benefits of immunotherapy with activated T and NK lymphocytes derived from patients with advanced cancer.

Published in:

Cancer Immunology, Immunotherapy, 2013, v. 62, n. 6, p. 1029, doi. 10.1007/s00262-013-1419-5

By:

Onishi, Hideya;
Morisaki, Takashi;
Kiyota, Akifumi;
Koya, Norihiro;
Tanaka, Hiroto;
Umebayashi, Masayo;
Katano, Mitsuo

Publication type:

Article

Inclusive estimation of complex antigen presentation functions of monocyte-derived dendritic cells differentiated under normoxia and hypoxia conditions.

Published in:

Cancer Immunology, Immunotherapy, 2012, v. 61, n. 3, p. 409, doi. 10.1007/s00262-011-1112-5

By:

Ogino, Toshitatsu;
Onishi, Hideya;
Suzuki, Hiroyuki;
Morisaki, Takashi;
Tanaka, Masao;
Katano, Mitsuo

Publication type:

Article

Nuclear factor kappaB-activated monocytes contribute to pancreatic cancer progression through the production of Shh.

Published in:

Cancer Immunology, Immunotherapy, 2010, v. 59, n. 5, p. 675, doi. 10.1007/s00262-009-0783-7

By:

Yamasaki, Akio;
Kameda, Chizu;
Xu, Rui;
Tanaka, Haruo;
Tasaka, Takehiko;
Chikazawa, Nobuhito;
Suzuki, Hiroyuki;
Morisaki, Takashi;
Kubo, Makoto;
Onishi, Hideya;
Tanaka, Masao;
Katano, Mitsuo

Publication type:

Article

Intratumoral CD8+ T/FOXP3+ cell ratio is a predictive marker for survival in patients with colorectal cancer.

Published in:

Cancer Immunology, Immunotherapy, 2010, v. 59, n. 5, p. 653, doi. 10.1007/s00262-009-0781-9

By:

Suzuki, Hiroyuki;
Chikazawa, Nobuhito;
Tasaka, Takehiko;
Wada, Junji;
Yamasaki, Akio;
Kitaura, Yoshiki;
Sozaki, Masae;
Tanaka, Masao;
Onishi, Hideya;
Morisaki, Takashi;
Katano, Mitsuo

Publication type:

Article

Monocyte-derived dendritic cells that capture dead tumor cells secrete IL-12 and TNF-a through IL-12/TNF-a/NF-?B autocrine loop.

Published in:

Cancer Immunology, Immunotherapy, 2004, v. 53, n. 12, p. 1093, doi. 10.1007/s00262-004-0568-y

By:

Onishi, Hideya;
Kuroki, Hideo;
Matsumoto, Kotaro;
Baba, Eishi;
Sasaki, Nobuhiko;
Kuga, Hirotaka;
Tanaka, Masao;
Katano, Mitsuo;
Morisaki, Takashi

Publication type:

Article

Streptococcal preparation OK-432: a new maturation factor of monocyte-derived dendritic cells for clinical use.

Published in:

Cancer Immunology, Immunotherapy, 2003, v. 52, n. 9, p. 561, doi. 10.1007/s00262-003-0394-7

By:

Kuroki, Hideo;
Morisaki, Takashi;
Matsumoto, Kotaro;
Onishi, Hideya;
Baba, Eishi;
Tanaka, Masao;
Katano, Mitsuo

Publication type:

Article

Neoantigen peptide-pulsed dendritic cell vaccine therapy after surgical treatment of pancreatic cancer: a retrospective study.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1571182

By:

Oyama, Koki;
Nakata, Kohei;
Abe, Toshiya;
Hirotaka, Kento;
Fujimori, Nao;
Kiyotani, Kazuma;
Iwamoto, Chika;
Ikenaga, Naoki;
Morisaki, Shinji;
Umebayashi, Masayo;
Tanaka, Hiroto;
Koya, Norihiro;
Nakagawa, Shinichiro;
Tsujimura, Kenta;
Yoshimura, Sachiko;
Onishi, Hideya;
Nakamura, Yusuke;
Nakamura, Masafumi;
Morisaki, Takashi

Publication type:

Article

Neoantigen peptide-pulsed dendritic cell vaccine therapy after surgical treatment of pancreatic cancer: a retrospective study.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1571182

By:

Oyama, Koki;
Nakata, Kohei;
Abe, Toshiya;
Hirotaka, Kento;
Fujimori, Nao;
Kiyotani, Kazuma;
Iwamoto, Chika;
Ikenaga, Naoki;
Morisaki, Shinji;
Umebayashi, Masayo;
Tanaka, Hiroto;
Koya, Norihiro;
Nakagawa, Shinichiro;
Tsujimura, Kenta;
Yoshimura, Sachiko;
Onishi, Hideya;
Nakamura, Yusuke;
Nakamura, Masafumi;
Morisaki, Takashi

Publication type:

Article

Nuclear expression of Y-box binding protein-1 is associated with poor prognosis in patients with pancreatic cancer and its knockdown inhibits tumor growth and metastasis in mice tumor models.

Published in:

International Journal of Cancer, 2016, v. 139, n. 2, p. 433, doi. 10.1002/ijc.30075

By:

Shinkai, Kentaro;
Nakano, Kenji;
Cui, Lin;
Mizuuchi, Yusuke;
Onishi, Hideya;
Oda, Yoshinao;
Obika, Satoshi;
Tanaka, Masao;
Katano, Mitsuo

Publication type:

Article

Claudin18.2-positive gastric cancer-specific changes in neoadjuvant chemotherapy-driven immunosuppressive tumor microenvironment.

Published in:

British Journal of Cancer, 2025, v. 132, n. 9, p. 793, doi. 10.1038/s41416-025-02981-y

By:

Tsutsumi, Chikanori;
Ohuchida, Kenoki;
Yamada, Yutaka;
Shimada, Yuki;
Imamura, Masaki;
Son, Kiwa;
Mochida, Yuki;
Katayama, Naoki;
Iwamoto, Chika;
Torata, Nobuhiro;
Horioka, Kohei;
Shindo, Koji;
Mizuuchi, Yusuke;
Ikenaga, Naoki;
Nakata, Kohei;
Onishi, Hideya;
Oda, Yoshinao;
Nakamura, Masafumi

Publication type:

Article

Establishment and characterization of a primary cell culture derived from external auditory canal squamous cell carcinoma.

Published in:

FEBS Open Bio, 2021, v. 11, n. 8, p. 2211, doi. 10.1002/2211-5463.13225

By:

Sekino, Yuki;
Imaizumi, Akira;
Komune, Noritaka;
Ono, Mayumi;
Sato, Kuniaki;
Masuda, Shogo;
Fujimura, Akiko;
Koike, Kensuke;
Hongo, Takahiro;
Uchi, Ryutaro;
Onishi, Hideya;
Nakagawa, Takashi

Publication type:

Article

Interferon-? suppresses transforming growth factor-ß-induced invasion of gastric carcinoma cells through cross-talk of Smad pathway in a three-dimensional culture model.

Published in:

Oncogene, 2003, v. 22, n. 49, p. 7838, doi. 10.1038/sj.onc.1207046

By:

Kuga, Hirotaka;
Morisaki, Takashi;
Nakamura, Katsuya;
Onishi, Hideya;
Noshiro, Hirokazu;
Uchiyama, Akihiko;
Tanaka, Masao;
Katano, Mitsuo

Publication type:

Article

Lymph Nodes as Anti-Tumor Immunotherapeutic Tools: Intranodal-Tumor-Specific Antigen-Pulsed Dendritic Cell Vaccine Immunotherapy.

Published in:

Cancers, 2022, v. 14, n. 10, p. 2438, doi. 10.3390/cancers14102438

By:

Morisaki, Takashi;
Morisaki, Takafumi;
Kubo, Makoto;
Morisaki, Shinji;
Nakamura, Yusuke;
Onishi, Hideya

Publication type:

Article

Pancreatic Juice Exosomal MicroRNAs as Biomarkers for Detection of Pancreatic Ductal Adenocarcinoma.

Published in:

Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2019, v. 26, n. 7, p. 2104, doi. 10.1245/s10434-019-07269-z

By:

Nakamura, So;
Sadakari, Yoshihiko;
Ohtsuka, Takao;
Okayama, Takafumi;
Nakashima, Yohei;
Gotoh, Yoshitaka;
Saeki, Kiyoshi;
Mori, Yasuhisa;
Nakata, Kohei;
Miyasaka, Yoshihiro;
Onishi, Hideya;
Oda, Yoshinao;
Goggins, Michael;
Nakamura, Masafumi

Publication type:

Article

Long-term survival of a patient with recurrent gallbladder carcinoma, treated with chemotherapy, immunotherapy, and surgery: a case report.

Published in:

2018

By:

Kawamoto, Makoto;
Wada, Yoshiyuki;
Koya, Norihiro;
Takami, Yuko;
Saitsu, Hideki;
Ishizaki, Naoki;
Tabata, Mineo;
Onishi, Hideya;
Nakamura, Masafumi;
Morisaki, Takashi

Publication type:

Case Study

Stage IV gastric cancer successfully treated by multidisciplinary therapy including chemotherapy, immunotherapy, and surgery: a case report.

Published in:

Surgical Case Reports, 2017, v. 3, n. 1, p. 1, doi. 10.1186/s40792-017-0380-5

By:

Kawamoto, Makoto;
Onishi, Hideya;
Koya, Norihiro;
Konomi, Hiroyuki;
Mitsugi, Kenji;
Tanaka, Risa;
Motoshita, Junichi;
Morisaki, Takashi;
Nakamura, Masafumi

Publication type:

Article

VEGFR2 is selectively expressed by FOXP3.

Published in:

European Journal of Immunology, 2010, v. 40, n. 1, p. 197, doi. 10.1002/eji.200939887

By:

Suzuki, Hiroyuki;
Onishi, Hideya;
Wada, Junji;
Yamasaki, Akio;
Tanaka, Haruo;
Nakano, Kenji;
Morisaki, Takashi;
Katano, Mitsuo

Publication type:

Article