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Mortality Associations With DNA Methylation-Based Biological Aging and Physical Functioning Measures Across a 20-Year Follow-up Period.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2023, v. 78, n. 8, p. 1489, doi. 10.1093/gerona/glad026
By:
- Föhr, Tiina;
- Waller, Katja;
- Viljanen, Anne;
- Rantanen, Taina;
- Kaprio, Jaakko;
- Ollikainen, Miina;
- Sillanpää, Elina
Publication type:
Article
Do Epigenetic Clocks Provide Explanations for Sex Differences in Life Span? A Cross-Sectional Twin Study.
Published in:
2022
By:
- Kankaanpää, Anna;
- Tolvanen, Asko;
- Saikkonen, Pirkko;
- Heikkinen, Aino;
- Laakkonen, Eija K;
- Kaprio, Jaakko;
- Ollikainen, Miina;
- Sillanpää, Elina
Publication type:
journal article
The Association Between Epigenetic Clocks and Physical Functioning in Older Women: A 3-Year Follow-up.
Published in:
2022
By:
- Föhr, Tiina;
- Törmäkangas, Timo;
- Lankila, Hannamari;
- Viljanen, Anne;
- Rantanen, Taina;
- Ollikainen, Miina;
- Kaprio, Jaakko;
- Sillanpää, Elina
Publication type:
journal article
Leisure-time physical activity and DNA methylation age—a twin study.
Published in:
Clinical Epigenetics, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13148-019-0613-5
By:
- Sillanpää, Elina;
- Ollikainen, Miina;
- Kaprio, Jaakko;
- Wang, Xiaoling;
- Leskinen, Tuija;
- Kujala, Urho M.;
- Törmäkangas, Timo
Publication type:
Article
Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci.
Published in:
Clinical Epigenetics, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13148-018-0606-9
By:
- Gupta, Richa;
- van Dongen, Jenny;
- Fu, Yu;
- Abdellaoui, Abdel;
- Tyndale, Rachel F.;
- Velagapudi, Vidya;
- Boomsma, Dorret I.;
- Korhonen, Tellervo;
- Kaprio, Jaakko;
- Loukola, Anu;
- Ollikainen, Miina
Publication type:
Article
Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health.
Published in:
Clinical Epigenetics, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13148-018-0558-0
By:
- Tsai, Pei-Chien;
- Glastonbury, Craig A.;
- Eliot, Melissa N.;
- Bollepalli, Sailalitha;
- Yet, Idil;
- Castillo-Fernandez, Juan E.;
- Carnero-Montoro, Elena;
- Hardiman, Thomas;
- Martin, Tiphaine C.;
- Vickers, Alice;
- Mangino, Massimo;
- Ward, Kirsten;
- Pietiläinen, Kirsi H.;
- Deloukas, Panos;
- Spector, Tim D.;
- Viñuela, Ana;
- Loucks, Eric B.;
- Ollikainen, Miina;
- Kelsey, Karl T.;
- Small, Kerrin S.
Publication type:
Article
Differences in DNA Methylation-Based Age Prediction Within Twin Pairs Discordant for Cancer.
Published in:
2022
By:
- Bode, Hannes F.;
- Heikkinen, Aino;
- Lundgren, Sara;
- Kaprio, Jaakko;
- Ollikainen, Miina
Publication type:
journal article
The Older Finnish Twin Cohort - 45 Years of Follow-up.
Published in:
2019
By:
- Kaprio, Jaakko;
- Bollepalli, Sailalitha;
- Buchwald, Jadwiga;
- Iso-Markku, Paula;
- Korhonen, Tellervo;
- Kovanen, Vuokko;
- Kujala, Urho;
- Laakkonen, Eija K.;
- Latvala, Antti;
- Leskinen, Tuija;
- Lindgren, Noora;
- Ollikainen, Miina;
- Piirtola, Maarit;
- Rantanen, Taina;
- Rinne, Juha;
- Rose, Richard J.;
- Sillanpää, Elina;
- Silventoinen, Karri;
- Sipilä, Sarianna;
- Viljanen, Anne
Publication type:
journal article
Hormone Replacement Therapy Associated White Blood Cell DNA Methylation and Gene Expression are Associated With Within-Pair Differences of Body Adiposity and Bone Mass.
Published in:
2015
By:
- Bahl, Aileen;
- Pöllänen, Eija;
- Ismail, Khadeeja;
- Sipilä, Sarianna;
- Mikkola, Tuija M.;
- Berglund, Eva;
- Lindqvist, Carl Mårten;
- Syvänen, Ann-Christine;
- Rantanen, Taina;
- Kaprio, Jaakko;
- Kovanen, Vuokko;
- Ollikainen, Miina;
- Craig, Jeff;
- Saffery, Richard;
- Pöllänen, Eija;
- Sipilä, Sarianna;
- Lindqvist, Carl Mårten;
- Syvänen, Ann-Christine
Publication type:
journal article
The Peri/Postnatal Epigenetic Twins Study (PETS).
Published in:
Twin Research & Human Genetics, 2013, v. 16, n. 1, p. 13, doi. 10.1017/thg.2012.114
By:
- Loke, Yuk Jing;
- Novakovic, Boris;
- Ollikainen, Miina;
- Wallace, Euan M.;
- Umstad, Mark P.;
- Permezel, Michael;
- Morley, Ruth;
- Ponsonby, Anne-Louise;
- Gordon, Lavinia;
- Galati, John C.;
- Saffery, Richard;
- Craig, Jeffrey M.
Publication type:
Article
Modeling dependency structures in 450k DNA methylation data.
Published in:
Bioinformatics, 2022, v. 38, n. 4, p. 885, doi. 10.1093/bioinformatics/btab774
By:
- Nustad, Haakon E;
- Steinsland, Ingelin;
- Ollikainen, Miina;
- Cazaly, Emma;
- Kaprio, Jaakko;
- Benjamini, Yuval;
- Gervin, Kristina;
- Lyle, Robert
Publication type:
Article
The association between night shift work and breast cancer risk in the Finnish twins cohort.
Published in:
European Journal of Epidemiology, 2023, v. 38, n. 5, p. 533, doi. 10.1007/s10654-023-00983-9
By:
- Schernhammer, Eva;
- Bogl, Leonie;
- Hublin, Christer;
- Strohmaier, Susanne;
- Zebrowska, Magda;
- Erber, Astrid;
- Haghayegh, Shahab;
- Papantoniou, Kyriaki;
- Ollikainen, Miina;
- Kaprio, Jaakko
Publication type:
Article
DNA methylation sites in early adulthood characterised by pubertal timing and development: a twin study.
Published in:
Clinical Epigenetics, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13148-023-01594-7
By:
- Sehovic, Emir;
- Zellers, Stephanie M.;
- Youssef, Markus K.;
- Heikkinen, Aino;
- Kaprio, Jaakko;
- Ollikainen, Miina
Publication type:
Article
Biological clocks and physical functioning in monozygotic female twins.
Published in:
2018
By:
- Sillanpää, Elina;
- Laakkonen, Eija K.;
- Vaara, Elina;
- Rantanen, Taina;
- Kovanen, Vuokko;
- Sipilä, Sarianna;
- Kaprio, Jaakko;
- Ollikainen, Miina;
- Sillanpää, Elina;
- Sipilä, Sarianna
Publication type:
journal article
Lifestyle differences between co-twins are associated with decreased similarity in their internal and external exposome profiles.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-72354-7
By:
- Drouard, Gabin;
- Wang, Zhiyang;
- Heikkinen, Aino;
- Foraster, Maria;
- Julvez, Jordi;
- Kanninen, Katja M.;
- van Kamp, Irene;
- Pirinen, Matti;
- Ollikainen, Miina;
- Kaprio, Jaakko
Publication type:
Article
Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations.
Published in:
Oncogene, 2005, v. 24, n. 9, p. 1542, doi. 10.1038/sj.onc.1208387
By:
- Abdel-Rahman, Wael M.;
- Ollikainen, Miina;
- Kariola, Reetta;
- Järvinen, Heikki J.;
- Mecklin, Jukka-Pekka;
- Nyström-Lahti, Minna;
- Knuutila, Sakari;
- Peltomäki, Päivi
Publication type:
Article
Lymphoma-Associated Biomarkers Are Increased in Current Smokers in Twin Pairs Discordant for Smoking.
Published in:
Cancers, 2021, v. 13, n. 21, p. 5395, doi. 10.3390/cancers13215395
By:
- Wang, Jun;
- Conti, David V.;
- Epeldegui, Marta;
- Ollikainen, Miina;
- Tyndale, Rachel F.;
- Hwang, Amie Eunah;
- Magpantay, Larry;
- Mack, Thomas McCulloch;
- Martinez-Maza, Otoniel;
- Kaprio, Jaakko;
- Cozen, Wendy
Publication type:
Article
BMI is positively associated with accelerated epigenetic aging in twin pairs discordant for body mass index.
Published in:
Journal of Internal Medicine, 2022, v. 292, n. 4, p. 627, doi. 10.1111/joim.13528
By:
- Lundgren, Sara;
- Kuitunen, Sara;
- Pietiläinen, Kirsi H.;
- Hurme, Mikko;
- Kähönen, Mika;
- Männistö, Satu;
- Perola, Markus;
- Lehtimäki, Terho;
- Raitakari, Olli;
- Kaprio, Jaakko;
- Ollikainen, Miina
Publication type:
Article
The potential of DNA methylation as a biomarker for obesity and smoking.
Published in:
Journal of Internal Medicine, 2022, v. 292, n. 3, p. 390, doi. 10.1111/joim.13496
By:
- Heikkinen, Aino;
- Bollepalli, Sailalitha;
- Ollikainen, Miina
Publication type:
Article
Copy number alterations of the polycomb gene BMI1 in gliomas.
Published in:
Acta Neuropathologica, 2008, v. 116, n. 1, p. 97, doi. 10.1007/s00401-008-0376-0
By:
- Häyry, Valtteri;
- Tanner, Minna;
- Blom, Tea;
- Tynninen, Olli;
- Roselli, Annariikka;
- Ollikainen, Miina;
- Sariola, Hannu;
- Wartiovaara, Kirmo;
- Nupponen, Nina N.
Publication type:
Article
Patterns of PIK3CA alterations in familial colorectal and endometrial carcinoma.
Published in:
International Journal of Cancer, 2007, v. 121, n. 4, p. 915, doi. 10.1002/ijc.22768
By:
- Ollikainen, Miina;
- Gylling, Annette;
- Puputti, Marjut;
- Nupponen, Nina N.;
- Abdel-Rahman, Wael M.;
- Butzow, Ralf;
- Peltomäki, Päivi
Publication type:
Article
Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance.
Published in:
Genome Biology, 2013, v. 14, n. 5, p. 1, doi. 10.1186/gb-2013-14-5-r42
By:
- Martino, David;
- Loke, Yuk Jin;
- Gordon, Lavinia;
- Ollikainen, Miina;
- Cruickshank, Mark N.;
- Saffery, Richard;
- Craig, Jeffrey M.
Publication type:
Article
Exploring machine learning strategies for predicting cardiovascular disease risk factors from multi-omic data.
Published in:
BMC Medical Informatics & Decision Making, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12911-024-02521-3
By:
- Drouard, Gabin;
- Mykkänen, Juha;
- Heiskanen, Jarkko;
- Pohjonen, Joona;
- Ruohonen, Saku;
- Pahkala, Katja;
- Lehtimäki, Terho;
- Wang, Xiaoling;
- Ollikainen, Miina;
- Ripatti, Samuli;
- Pirinen, Matti;
- Raitakari, Olli;
- Kaprio, Jaakko
Publication type:
Article
The role of adolescent lifestyle habits in biological aging: A prospective twin study.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.80729
By:
- Kankaanpää, Anna;
- Tolvanen, Asko;
- Heikkinen, Aino;
- Kaprio, Jaakko;
- Ollikainen, Miina;
- Sillanpää, Elina
Publication type:
Article
Genetic meta-analysis of twin birth weight shows high genetic correlation with singleton birth weight.
Published in:
Human Molecular Genetics, 2021, v. 30, n. 19, p. 1894, doi. 10.1093/hmg/ddab121
By:
- Beck, Jeffrey J;
- Pool, René;
- van de Weijer, Margot;
- Chen, Xu;
- Krapohl, Eva;
- Gordon, Scott D;
- Nygaard, Marianne;
- Debrabant, Birgit;
- Palviainen, Teemu;
- Zee, Matthijs D van der;
- Baselmans, Bart;
- Finnicum, Casey T;
- Yi, Lu;
- Lundström, Sebastian;
- Beijsterveldt, Toos van;
- Christiansen, Lene;
- Heikkilä, Kauko;
- Kittelsrud, Julie;
- Loukola, Anu;
- Ollikainen, Miina
Publication type:
Article
Correction to: Does the epigenetic clock GrimAge predict mortality independent of genetic influences: an 18 year follow-up study in older female twin pairs.
Published in:
2021
By:
- Föhr, Tiina;
- Waller, Katja;
- Viljanen, Anne;
- Sanchez, Riikka;
- Ollikainen, Miina;
- Rantanen, Taina;
- Kaprio, Jaakko;
- Sillanpää, Elina
Publication type:
Correction Notice
Does the epigenetic clock GrimAge predict mortality independent of genetic influences: an 18 year follow-up study in older female twin pairs.
Published in:
Clinical Epigenetics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13148-021-01112-7
By:
- Föhr, Tiina;
- Waller, Katja;
- Viljanen, Anne;
- Sanchez, Riikka;
- Ollikainen, Miina;
- Rantanen, Taina;
- Kaprio, Jaakko;
- Sillanpää, Elina
Publication type:
Article
Does the epigenetic clock GrimAge predict mortality independent of genetic influences: an 18 year follow-up study in older female twin pairs.
Published in:
Clinical Epigenetics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13148-021-01112-7
By:
- Tiina, Föhr;
- Katja, Waller;
- Anne, Viljanen;
- Riikka, Sanchez;
- Miina, Ollikainen;
- Taina, Rantanen;
- Jaakko, Kaprio;
- Sillanpää, Elina
Publication type:
Article
Blood and skeletal muscle ageing determined by epigenetic clocks and their associations with physical activity and functioning.
Published in:
Clinical Epigenetics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13148-021-01094-6
By:
- Sillanpää, Elina;
- Heikkinen, Aino;
- Kankaanpää, Anna;
- Paavilainen, Aini;
- Kujala, Urho M.;
- Tammelin, Tuija H.;
- Kovanen, Vuokko;
- Sipilä, Sarianna;
- Pietiläinen, Kirsi H.;
- Kaprio, Jaakko;
- Ollikainen, Miina;
- Laakkonen, Eija K.
Publication type:
Article
Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer's disease.
Published in:
Clinical Epigenetics, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13148-019-0729-7
By:
- Konki, Mikko;
- Malonzo, Maia;
- Karlsson, Ida K.;
- Lindgren, Noora;
- Ghimire, Bishwa;
- Smolander, Johannes;
- Scheinin, Noora M.;
- Ollikainen, Miina;
- Laiho, Asta;
- Elo, Laura L.;
- Lönnberg, Tapio;
- Röyttä, Matias;
- Pedersen, Nancy L.;
- Kaprio, Jaakko;
- Lähdesmäki, Harri;
- Rinne, Juha O.;
- Lund, Riikka J.
Publication type:
Article
APC and β-catenin protein expression patterns in HNPCC-related endometrial and colorectal cancers.
Published in:
Familial Cancer, 2005, v. 4, n. 2, p. 187, doi. 10.1007/s10689-004-6130-4
By:
- Reetta Kariola;
- Wael M. Abdel-Rahman;
- Miina Ollikainen;
- Ralf Butzow;
- Päivi Peltomäki;
- Minna Nyström
Publication type:
Article
Mendelian randomization in (epi)genetic epidemiology: an effective tool to be handled with care.
Published in:
Genome Biology, 2016, v. 17, p. 1, doi. 10.1186/s13059-016-1018-9
By:
- Latvala, Antti;
- Ollikainen, Miina
Publication type:
Article
A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism.
Published in:
PLoS Genetics, 2015, v. 11, n. 9, p. 1, doi. 10.1371/journal.pgen.1005498
By:
- Loukola, Anu;
- Buchwald, Jadwiga;
- Gupta, Richa;
- Palviainen, Teemu;
- Hällfors, Jenni;
- Tikkanen, Emmi;
- Korhonen, Tellervo;
- Ollikainen, Miina;
- Sarin, Antti-Pekka;
- Ripatti, Samuli;
- Lehtimäki, Terho;
- Raitakari, Olli;
- Salomaa, Veikko;
- Rose, Richard J.;
- Tyndale, Rachel F.;
- Kaprio, Jaakko
Publication type:
Article
Somatic FGF9 mutations in colorectal and endometrial carcinomas associated with membranous β-catenin.
Published in:
Human Mutation, 2008, v. 29, n. 3, p. 390, doi. 10.1002/humu.20653
By:
- Abdel-Rahman, Wael M.;
- Kalinina, Juliya;
- Shoman, Soheir;
- Eissa, Saad;
- Ollikainen, Miina;
- Elomaa, Outi;
- Eliseenkova, Anna V.;
- Bützow, Ralf;
- Mohammadi, Moosa;
- Peltomäki, Päivi
Publication type:
Article
Cohort Profile: The Peri/post-natal Epigenetic Twins Study.
Published in:
International Journal of Epidemiology, 2012, v. 41, n. 1, p. 55, doi. 10.1093/ije/dyr140
By:
- Saffery, Richard;
- Morley, Ruth;
- Carlin, John B;
- Joo, Ji-Hoon Eric;
- Ollikainen, Miina;
- Novakovic, Boris;
- Andronikos, Roberta;
- Li, Xin;
- Loke, Yuk Jing;
- Carson, Nicole;
- Wallace, Euan M;
- Umstad, Mark P;
- Permezel, Michael;
- Galati, John C;
- Craig, Jeffrey M
Publication type:
Article
DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome.
Published in:
Human Molecular Genetics, 2010, v. 19, n. 21, p. 4176, doi. 10.1093/hmg/ddq336
By:
- Ollikainen, Miina;
- Smith, Katherine R.;
- Joo, Eric Ji-Hoon;
- Ng, Hong Kiat;
- Andronikos, Roberta;
- Novakovic, Boris;
- Abdul Aziz, Nur Khairunnisa;
- Carlin, John B.;
- Morley, Ruth;
- Saffery, Richard;
- Craig, Jeffrey M.
Publication type:
Article
Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status.
Published in:
Human Molecular Genetics, 2004, v. 13, n. 19, p. 2303, doi. 10.1093/hmg/ddh238
By:
- Oliveira, Carla;
- Westra, Jantine L.;
- Arango, Diego;
- Ollikainen, Miina;
- Domingo, Enric;
- Ferreira, Ana;
- Velho, Sérgia;
- Niessen, Renee;
- Lagerstedt, Kristina;
- Alhopuro, Pia;
- Laiho, Paivi;
- Veiga, Isabel;
- Teixeira, Manuel R.;
- Ligtenberg, Marjolijn;
- Kleibeuker, Jan H.;
- Sijmons, Rolf H.;
- Plukker, John T.;
- Imai, Kohzoh;
- Lage, Pedro;
- Hamelin, Richard
Publication type:
Article
A Bivariate Twin Study of Lifetime cannabis Initiation and Lifetime Regular Tobacco Smoking Across Three Different Countries.
Published in:
Behavior Genetics, 2024, v. 54, n. 5, p. 375, doi. 10.1007/s10519-024-10190-1
By:
- Zellers, Stephanie;
- van Dongen, Jenny;
- Maes, Hermine H.M.;
- Ollikainen, Miina;
- Fang, Fang;
- Vrieze, Scott;
- Kaprio, Jaakko;
- Boomsma, Dorret I.
Publication type:
Article
Impaired Mitochondrial Biogenesis in Adipose Tissue in Acquired Obesity.
Published in:
Diabetes, 2015, v. 64, n. 9, p. 3135, doi. 10.2337/db14-1937
By:
- Heinonen, Sini;
- Buzkova, Jana;
- Muniandy, Maheswary;
- Kaksonen, Risto;
- Ollikainen, Miina;
- Ismail, Khadeeja;
- Hakkarainen, Antti;
- Lundbom, Jesse;
- Lundbom, Nina;
- Vuolteenaho, Katriina;
- Moilanen, Eeva;
- Kaprio, Jaakko;
- Rissanen, Aila;
- Suomalainen, Anu;
- Pietiläinen, Kirsi H.
Publication type:
Article

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