Works by Okonechnikov, Konstantin

Results: 38
    1

    Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-023-44117-x
    By:
    • Ghasemi, David R.;
    • Okonechnikov, Konstantin;
    • Rademacher, Anne;
    • Tirier, Stephan;
    • Maass, Kendra K.;
    • Schumacher, Hanna;
    • Joshi, Piyush;
    • Gold, Maxwell P.;
    • Sundheimer, Julia;
    • Statz, Britta;
    • Rifaioglu, Ahmet S.;
    • Bauer, Katharina;
    • Schumacher, Sabrina;
    • Bortolomeazzi, Michele;
    • Giangaspero, Felice;
    • Ernst, Kati J.;
    • Clifford, Steven C.;
    • Saez-Rodriguez, Julio;
    • Jones, David T. W.;
    • Kawauchi, Daisuke
    Publication type:
    Article
    2
    3
    4
    5
    6

    Subgroup and subtype-specific outcomes in adult medulloblastoma.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 5, p. 859, doi. 10.1007/s00401-021-02358-4
    By:
    • Coltin, Hallie;
    • Sundaresan, Lakshmikirupa;
    • Smith, Kyle S.;
    • Skowron, Patryk;
    • Massimi, Luca;
    • Eberhart, Charles G.;
    • Schreck, Karisa C.;
    • Gupta, Nalin;
    • Weiss, William A.;
    • Tirapelli, Daniela;
    • Carlotti, Carlos;
    • Li, Kay K. W.;
    • Ryzhova, Marina;
    • Golanov, Andrey;
    • Zheludkova, Olga;
    • Absalyamova, Oksana;
    • Okonechnikov, Konstantin;
    • Stichel, Damian;
    • von Deimling, Andreas;
    • Giannini, Caterina
    Publication type:
    Article
    7

    Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 5, p. 827, doi. 10.1007/s00401-021-02356-6
    By:
    • Sievers, Philipp;
    • Henneken, Sophie C.;
    • Blume, Christina;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Okonechnikov, Konstantin;
    • Reuss, David E.;
    • Benzel, Julia;
    • Maaß, Kendra K.;
    • Kool, Marcel;
    • Sturm, Dominik;
    • Zheng, Tuyu;
    • Ghasemi, David R.;
    • Kohlhof-Meinecke, Patricia;
    • Cruz, Ofelia;
    • Suñol, Mariona;
    • Lavarino, Cinzia;
    • Ruf, Viktoria;
    • Boldt, Henning B.
    Publication type:
    Article
    8

    Targeting fibroblast growth factor receptors to combat aggressive ependymoma.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 2, p. 339, doi. 10.1007/s00401-021-02327-x
    By:
    • Lötsch, Daniela;
    • Kirchhofer, Dominik;
    • Englinger, Bernhard;
    • Jiang, Li;
    • Okonechnikov, Konstantin;
    • Senfter, Daniel;
    • Laemmerer, Anna;
    • Gabler, Lisa;
    • Pirker, Christine;
    • Donson, Andrew M.;
    • Bannauer, Peter;
    • Korbel, Pia;
    • Jaunecker, Carola N.;
    • Hübner, Jens-Martin;
    • Mayr, Lisa;
    • Madlener, Sibylle;
    • Schmook, Maria T.;
    • Ricken, Gerda;
    • Maaß, Kendra;
    • Grusch, Michael
    Publication type:
    Article
    9

    Transcriptional profiling of medulloblastoma with extensive nodularity (MBEN) reveals two clinically relevant tumor subsets with VSNL1 as potent prognostic marker.

    Published in:
    Acta Neuropathologica, 2020, v. 139, n. 3, p. 583, doi. 10.1007/s00401-019-02102-z
    By:
    • Korshunov, Andrey;
    • Okonechnikov, Konstantin;
    • Sahm, Felix;
    • Ryzhova, Marina;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Ghasemi, David R.;
    • Pajtler, Kristian W.;
    • Antonelli, Manila;
    • Donofrio, Vittoria;
    • Mastronuzzi, Angela;
    • Rossi, Sabrina;
    • Camassei, Francesca Diomedi;
    • Buccoliero, Anna Maria;
    • Haberler, Christine;
    • Slavc, Irene;
    • Dahiya, Sonika;
    • Casalini, Belen;
    • Sievers, Philipp;
    • Meyer, Jochen
    Publication type:
    Article
    10

    MYCN amplification drives an aggressive form of spinal ependymoma.

    Published in:
    Acta Neuropathologica, 2019, v. 138, n. 6, p. 1075, doi. 10.1007/s00401-019-02056-2
    By:
    • Ghasemi, David R.;
    • Sill, Martin;
    • Okonechnikov, Konstantin;
    • Korshunov, Andrey;
    • Yip, Stephen;
    • Schutz, Peter W.;
    • Scheie, David;
    • Kruse, Anders;
    • Harter, Patrick N.;
    • Kastelan, Marina;
    • Wagner, Marlies;
    • Hartmann, Christian;
    • Benzel, Julia;
    • Maass, Kendra K.;
    • Khasraw, Mustafa;
    • Sträter, Ronald;
    • Thomas, Christian;
    • Paulus, Werner;
    • Kratz, Christian P.;
    • Witt, Hendrik
    Publication type:
    Article
    11

    Molecular progression of SHH-activated medulloblastomas.

    Published in:
    2019
    By:
    • Korshunov, Andrey;
    • Okonechnikov, Konstantin;
    • Sahm, Felix;
    • Ryzhova, Marina;
    • Stichel, Damian;
    • Sievers, Philipp;
    • Meyer, Jochen;
    • Schrimpf, Daniel;
    • Zheludkova, Olga;
    • Golanov, Andrey;
    • Lichter, Peter;
    • Jones, David T. W.;
    • Pfister, Stefan M.;
    • von Deimling, Andreas;
    • Kool, Marcel
    Publication type:
    Letter
    12

    Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) disclose similar epigenetic signatures but different transcriptional profiles.

    Published in:
    Acta Neuropathologica, 2019, v. 137, n. 6, p. 1003, doi. 10.1007/s00401-019-01981-6
    By:
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Casalini, Belen;
    • Sievers, Philipp;
    • Meyer, Jochen;
    • Sahm, Felix;
    • von Deimling, Andreas;
    • Korshunov, Andrey;
    • Jones, David T. W.;
    • Okonechnikov, Konstantin;
    • Kool, Marcel;
    • Pfister, Stefan M.;
    • Lichter, Peter;
    • Ryzhova, Marina;
    • Zheludkova, Olga;
    • Golanov, Andrey
    Publication type:
    Article
    13

    Mapping pediatric brain tumors to their origins in the developing cerebellum.

    Published in:
    Neuro-Oncology, 2023, v. 25, n. 10, p. 1895, doi. 10.1093/neuonc/noad124
    By:
    • Okonechnikov, Konstantin;
    • Joshi, Piyush;
    • Sepp, Mari;
    • Leiss, Kevin;
    • Sarropoulos, Ioannis;
    • Murat, Florent;
    • Sill, Martin;
    • Beck, Pengbo;
    • Chan, Kenneth Chun-Ho;
    • Korshunov, Andrey;
    • Sah, Felix;
    • Deng, Maximilian Y;
    • Sturm, Dominik;
    • DeSisto, John;
    • Donson, Andrew M;
    • Foreman, Nicholas K;
    • Green, Adam L;
    • Robinson, Giles;
    • Orr, Brent A;
    • Gao, Qingsong
    Publication type:
    Article
    14
    15

    Author Correction: Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability.

    Published in:
    2025
    By:
    • Smirnov, Petr;
    • Przybilla, Moritz J.;
    • Simovic-Lorenz, Milena;
    • Parra, R. Gonzalo;
    • Susak, Hana;
    • Ratnaparkhe, Manasi;
    • Wong, John KL.;
    • Körber, Verena;
    • Mallm, Jan-Philipp;
    • Philippos, George;
    • Sill, Martin;
    • Kolb, Thorsten;
    • Kumar, Rithu;
    • Casiraghi, Nicola;
    • Okonechnikov, Konstantin;
    • Ghasemi, David R.;
    • Maaß, Kendra Korinna;
    • Pajtler, Kristian W.;
    • Jauch, Anna;
    • Korshunov, Andrey
    Publication type:
    Correction Notice
    16

    Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54547-w
    By:
    • Smirnov, Petr;
    • Przybilla, Moritz J.;
    • Simovic-Lorenz, Milena;
    • Parra, R. Gonzalo;
    • Susak, Hana;
    • Ratnaparkhe, Manasi;
    • Wong, John KL.;
    • Körber, Verena;
    • Mallm, Jan-Philipp;
    • Philippos, George;
    • Sill, Martin;
    • Kolb, Thorsten;
    • Kumar, Rithu;
    • Casiraghi, Nicola;
    • Okonechnikov, Konstantin;
    • Ghasemi, David R.;
    • Maaß, Kendra Korinna;
    • Pajtler, Kristian W.;
    • Jauch, Anna;
    • Korshunov, Andrey
    Publication type:
    Article
    17

    Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-023-44117-x
    By:
    • Ghasemi, David R.;
    • Okonechnikov, Konstantin;
    • Rademacher, Anne;
    • Tirier, Stephan;
    • Maass, Kendra K.;
    • Schumacher, Hanna;
    • Joshi, Piyush;
    • Gold, Maxwell P.;
    • Sundheimer, Julia;
    • Statz, Britta;
    • Rifaioglu, Ahmet S.;
    • Bauer, Katharina;
    • Schumacher, Sabrina;
    • Bortolomeazzi, Michele;
    • Giangaspero, Felice;
    • Ernst, Kati J.;
    • Clifford, Steven C.;
    • Saez-Rodriguez, Julio;
    • Jones, David T. W.;
    • Kawauchi, Daisuke
    Publication type:
    Article
    18

    Author Correction: Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage.

    Published in:
    2024
    By:
    • Ghasemi, David R.;
    • Okonechnikov, Konstantin;
    • Rademacher, Anne;
    • Tirier, Stephan;
    • Maass, Kendra K.;
    • Schumacher, Hanna;
    • Joshi, Piyush;
    • Gold, Maxwell P.;
    • Sundheimer, Julia;
    • Statz, Britta;
    • Rifaioglu, Ahmet S.;
    • Bauer, Katharina;
    • Schumacher, Sabrina;
    • Bortolomeazzi, Michele;
    • Giangaspero, Felice;
    • Ernst, Kati J.;
    • Clifford, Steven C.;
    • Saez-Rodriguez, Julio;
    • Jones, David T. W.;
    • Kawauchi, Daisuke
    Publication type:
    Correction Notice
    19
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    Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling.

    Published in:
    Acta Neuropathologica Communications, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40478-024-01921-w
    By:
    • Okonechnikov, Konstantin;
    • Ghasemi, David R.;
    • Schrimpf, Daniel;
    • Tonn, Svenja;
    • Mynarek, Martin;
    • Koster, Jan;
    • Milde, Till;
    • Zheng, Tuyu;
    • Sievers, Philipp;
    • Sahm, Felix;
    • Jones, David T.W.;
    • von Deimling, Andreas;
    • Pfister, Stefan M.;
    • Kool, Marcel;
    • Pajtler, Kristian W.;
    • Korshunov, Andrey
    Publication type:
    Article
    22

    Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling.

    Published in:
    Acta Neuropathologica Communications, 2025, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01921-w
    By:
    • Okonechnikov, Konstantin;
    • Ghasemi, David R.;
    • Schrimpf, Daniel;
    • Tonn, Svenja;
    • Mynarek, Martin;
    • Koster, Jan;
    • Milde, Till;
    • Zheng, Tuyu;
    • Sievers, Philipp;
    • Sahm, Felix;
    • Jones, David T.W.;
    • von Deimling, Andreas;
    • Pfister, Stefan M.;
    • Kool, Marcel;
    • Pajtler, Kristian W.;
    • Korshunov, Andrey
    Publication type:
    Article
    23
    24

    Integrated molecular analysis of adult sonic hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator.

    Published in:
    Neuro-Oncology, 2021, v. 23, n. 9, p. 1576, doi. 10.1093/neuonc/noab031
    By:
    • Korshunov, Andrey;
    • Okonechnikov, Konstantin;
    • Stichel, Damian;
    • Ryzhova, Marina;
    • Schrimpf, Daniel;
    • Sahm, Felix;
    • Sievers, Philipp;
    • Absalyamova, Oksana;
    • Zheludkova, Olga;
    • Golanov, Andrey;
    • Jones, David T W;
    • Pfister, Stefan M;
    • Deimling, Andreas von;
    • Kool, Marcel
    Publication type:
    Article
    25

    The genetic landscape of choroid plexus tumors in children and adults.

    Published in:
    Neuro-Oncology, 2021, v. 23, n. 4, p. 650, doi. 10.1093/neuonc/noaa267
    By:
    • Thomas, Christian;
    • Soschinski, Patrick;
    • Zwaig, Melissa;
    • Oikonomopoulos, Spyridon;
    • Okonechnikov, Konstantin;
    • Pajtler, Kristian W;
    • Sill, Martin;
    • Schweizer, Leonille;
    • Koch, Arend;
    • Neumann, Julia;
    • Schüller, Ulrich;
    • Sahm, Felix;
    • Rauschenbach, Laurèl;
    • Keyvani, Kathy;
    • Proescholdt, Martin;
    • Riemenschneider, Markus J;
    • Segewiß, Jochen;
    • Ruckert, Christian;
    • Grauer, Oliver;
    • Monoranu, Camelia-Maria
    Publication type:
    Article
    26
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    29

    YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11884-5
    By:
    • Pajtler, Kristian W.;
    • Wei, Yiju;
    • Okonechnikov, Konstantin;
    • Silva, Patricia B. G.;
    • Vouri, Mikaella;
    • Zhang, Lei;
    • Brabetz, Sebastian;
    • Sieber, Laura;
    • Gulley, Melissa;
    • Mauermann, Monika;
    • Wedig, Tatjana;
    • Mack, Norman;
    • Imamura Kawasawa, Yuka;
    • Sharma, Tanvi;
    • Zuckermann, Marc;
    • Andreiuolo, Felipe;
    • Holland, Eric;
    • Maass, Kendra;
    • Körkel-Qu, Huiqin;
    • Liu, Hai-Kun
    Publication type:
    Article
    30
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    Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma.

    Published in:
    Life Science Alliance, 2021, v. 4, n. 5, p. 1, doi. 10.26508/lsa.201900332
    By:
    • Afanasyeva, Elena A.;
    • Gartlgruber, Moritz;
    • Ryl, Tatsiana;
    • Decaesteker, Bieke;
    • Denecker, Geertrui;
    • Mönke, Gregor;
    • Toprak, Umut H.;
    • Florez, Andres;
    • Torkov, Alica;
    • Dreidax, Daniel;
    • Herrmann, Carl;
    • Okonechnikov, Konstantin;
    • Ek, Sara;
    • Sharma, Ashwini Kumar;
    • Sagulenko, Vitaliya;
    • Speleman, Frank;
    • Henrich, Kai-Oliver;
    • Westermann, Frank
    Publication type:
    Article
    33
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    Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation.

    Published in:
    Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01118-5
    By:
    • Korshunov, Andrey;
    • Okonechnikov, Konstantin;
    • Schmitt-Hoffner, Felix;
    • Ryzhova, Marina;
    • Sahm, Felix;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Reuss, David E.;
    • Sievers, Philipp;
    • Suwala, Abigail Kora;
    • Kumirova, Ella;
    • Zheludkova, Olga;
    • Golanov, Andrey;
    • Jones, David T. W.;
    • Pfister, Stefan M.;
    • Kool, Marcel;
    • von Deimling, Andreas
    Publication type:
    Article
    36

    Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21247-8
    By:
    • Hartlieb, Sabine A.;
    • Sieverling, Lina;
    • Nadler-Holly, Michal;
    • Ziehm, Matthias;
    • Toprak, Umut H.;
    • Herrmann, Carl;
    • Ishaque, Naveed;
    • Okonechnikov, Konstantin;
    • Gartlgruber, Moritz;
    • Park, Young-Gyu;
    • Wecht, Elisa Maria;
    • Savelyeva, Larissa;
    • Henrich, Kai-Oliver;
    • Rosswog, Carolina;
    • Fischer, Matthias;
    • Hero, Barbara;
    • Jones, David T. W.;
    • Pfaff, Elke;
    • Witt, Olaf;
    • Pfister, Stefan M.
    Publication type:
    Article
    37

    3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38044-0
    By:
    • Okonechnikov, Konstantin;
    • Camgöz, Aylin;
    • Chapman, Owen;
    • Wani, Sameena;
    • Park, Donglim Esther;
    • Hübner, Jens-Martin;
    • Chakraborty, Abhijit;
    • Pagadala, Meghana;
    • Bump, Rosalind;
    • Chandran, Sahaana;
    • Kraft, Katerina;
    • Acuna-Hidalgo, Rocio;
    • Reid, Derek;
    • Sikkink, Kristin;
    • Mauermann, Monika;
    • Juarez, Edwin F.;
    • Jenseit, Anne;
    • Robinson, James T.;
    • Pajtler, Kristian W.;
    • Milde, Till
    Publication type:
    Article
    38

    Notch Signaling between Cerebellar Granule Cell Progenitors.

    Published in:
    eNeuro, 2021, v. 8, n. 3, p. 1, doi. 10.1523/ENEURO.0468-20.2021
    By:
    • Toma Adachi;
    • Satoshi Miyashita;
    • Mariko Yamashita;
    • Mana Shimoda;
    • Konstantin Okonechnikov;
    • Lukas Chavez;
    • Marcel Kool;
    • Stefan M. Pfister;
    • Takafumi Inoue;
    • Daisuke Kawauchi;
    • Mikio Hoshino
    Publication type:
    Article