Works by Okamoto, Ryo

Results: 55

Rapid Chemical Synthesis of Serine Protease Inhibitor Kazal‐type 13 (SPINK13) Glycoform by a Combined Method with Glycan Insertion Strategy and Fast‐Flow Fmoc SPPS**.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 42, p. 1, doi. 10.1002/chem.202300646

By:

Nomura, Kota;
Okamoto, Ryo;
Maki, Yuta;
Hayashibara, Ayumu;
Takao, Toshifumi;
Fukuoka, Tomoya;
Miyoshi, Eiji;
Pentelute, Bradley L.;
Kajihara, Yasuhiro

Publication type:

Article

Cover Feature: Regulating Antifreeze Activity through Water: Latent Functions of the Sugars of Antifreeze Glycoprotein Revealed by Total Chemical Synthesis (Chem. Eur. J. 21/2023).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 21, p. 1, doi. 10.1002/chem.202300690

By:

Okamoto, Ryo;
Orii, Ryo;
Shibata, Hiroyuki;
Maki, Yuta;
Tsuda, Sakae;
Kajihara, Yasuhiro

Publication type:

Article

Regulating Antifreeze Activity through Water: Latent Functions of the Sugars of Antifreeze Glycoprotein Revealed by Total Chemical Synthesis.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 21, p. 1, doi. 10.1002/chem.202203553

By:

Okamoto, Ryo;
Orii, Ryo;
Shibata, Hiroyuki;
Maki, Yuta;
Tsuda, Sakae;
Kajihara, Yasuhiro

Publication type:

Article

Design and Synthesis of Glycosylated Cholera Toxin B Subunit as a Tracer of Glycoprotein Trafficking in Organelles of Living Cells.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 37, p. 1, doi. 10.1002/chem.202201253

By:

Maki, Yuta;
Kawata, Kazuki;
Liu, Yanbo;
Goo, Kang‐Ying;
Okamoto, Ryo;
Kajihara, Yasuhiro;
Satoh, Ayano

Publication type:

Article

Synthesis of Glc1Man9-Glycoprotein Probes by a Misfolding/Enzymatic Glucosylation/Misfolding Sequence.

Published in:

Angewandte Chemie, 2016, v. 128, n. 12, p. 4036, doi. 10.1002/ange.201511491

By:

Izumi, Masayuki;
Oka, Yukiho;
Okamoto, Ryo;
Seko, Akira;
Takeda, Yoichi;
Ito, Yukishige;
Kajihara, Yasuhiro

Publication type:

Article

Total Chemical Synthesis and Biological Activities of Glycosylated and Non-Glycosylated Forms of the Chemokines CCL1 and Ser-CCL1.

Published in:

Angewandte Chemie, 2014, v. 126, n. 20, p. 5288, doi. 10.1002/ange.201310574

By:

Okamoto, Ryo;
Mandal, Kalyaneswar;
Ling, Morris;
Luster, Andrew D.;
Kajihara, Yasuhiro;
Kent, Stephen B. H.

Publication type:

Article

(Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis.

Published in:

Angewandte Chemie, 2014, v. 126, n. 20, p. 5294, doi. 10.1002/ange.201400679

By:

Okamoto, Ryo;
Mandal, Kalyaneswar;
Sawaya, Michael R.;
Kajihara, Yasuhiro;
Yeates, Todd O.;
Kent, Stephen B. H.

Publication type:

Article

Chemical Synthesis of an Erythropoietin Glycoform Containing a Complex-type Disialyloligosaccharide.

Published in:

Angewandte Chemie, 2012, v. 124, n. 15, p. 3627, doi. 10.1002/ange.201109034

By:

Murakami, Masumi;
Okamoto, Ryo;
Izumi, Masayuki;
Kajihara, Yasuhiro

Publication type:

Article

Innentitelbild: Chemical Synthesis of an Erythropoietin Glycoform Containing a Complex-type Disialyloligosaccharide (Angew. Chem. 15/2012).

Published in:

Angewandte Chemie, 2012, v. 124, n. 15, p. 3552, doi. 10.1002/ange.201200881

By:

Murakami, Masumi;
Okamoto, Ryo;
Izumi, Masayuki;
Kajihara, Yasuhiro

Publication type:

Article

A Synthetic Approach to a Peptide α-Thioester from an Unprotected Peptide through Cleavage and Activation of a Specific Peptide Bond by N-Acetylguanidine.

Published in:

Angewandte Chemie, 2012, v. 124, n. 1, p. 195, doi. 10.1002/ange.201105601

By:

Okamoto, Ryo;
Morooka, Keiko;
Kajihara, Yasuhiro

Publication type:

Article

Uncovering a Latent Ligation Site for Glycopeptide Synthesis.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 29, p. 5402, doi. 10.1002/anie.200801097

By:

Okamoto, Ryo;
Kajihara, Yasuhiro

Publication type:

Article

Chemical Modification of the N Termini of Unprotected Peptides for Semisynthesis of Modified Proteins by Utilizing a Hydrophilic Protecting Group.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 43, p. 10197, doi. 10.1002/chem.201901778

By:

Chandrashekar, Chaitra;
Okamoto, Ryo;
Izumi, Masayuki;
Kajihara, Yasuhiro

Publication type:

Article

Total Synthesis of O-GalNAcylated Antifreeze Glycoprotein using the Switchable Reactivity of Peptidyl- N-pivaloylguanidine.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 39, p. 9253, doi. 10.1002/chem.201702243

By:

Orii, Ryo;
Sakamoto, Noriko;
Fukami, Daichi;
Tsuda, Sakae;
Izumi, Masayuki;
Kajihara, Yasuhiro;
Okamoto, Ryo

Publication type:

Article

Chemical Synthesis of Glycoproteins with the Specific Installation of Gradient-Enriched 15N-Labeled Amino Acids for Getting Insights into Glycoprotein Behavior.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 27, p. 6579, doi. 10.1002/chem.201606049

By:

Minh Hien, Nguyen;
Izumi, Masayuki;
Sato, Hajime;
Okamoto, Ryo;
Kajihara, Yasuhiro

Publication type:

Article

Intraoperatively measured prehepatectomy portal vein pressure as a useful predictor of posthepatectomy liver failure.

Published in:

Langenbeck's Archives of Surgery, 2024, v. 409, n. 1, p. 1, doi. 10.1007/s00423-024-03508-4

By:

Nakajima, Takayoshi;
Ikuta, Shinichi;
Aihara, Tsukasa;
Ikuta, Lisa;
Matsuki, Goshi;
Fujikawa, Masataka;
Ichise, Noriko;
Okamoto, Ryo;
Nakamoto, Yoshihiko;
Yanagi, Hidenori;
Yamanaka, Naoki

Publication type:

Article

High hand grip strength is a significant risk factor and a useful predictor of postoperative pancreatic fistula following pancreaticoduodenectomy.

Published in:

Langenbeck's Archives of Surgery, 2024, v. 409, n. 1, p. 1, doi. 10.1007/s00423-024-03274-3

By:

Nakajima, Takayoshi;
Ikuta, Shinichi;
Fujikawa, Masataka;
Ikuta, Lisa;
Matsuki, Goshi;
Ichise, Noriko;
Kasai, Meidai;
Okamoto, Ryo;
Nakamoto, Yoshihiko;
Aihara, Tsukasa;
Yanagi, Hidenori;
Yamanaka, Naoki

Publication type:

Article

Post-translational activation of the C-terminus of polypeptides for the synthesis of peptide thioesters and peptide thioester surrogates.

Published in:

Frontiers in Chemistry, 2024, p. 1, doi. 10.3389/fchem.2024.1424953

By:

Liu, Yanbo;
Kajihara, Yasuhiro;
Okamoto, Ryo;
Yoshiya, Taku

Publication type:

Article

Isopeptide bond formation mediated by d-selenolysine for chemical ubiquitination.

Published in:

Frontiers in Chemistry, 2023, p. 1, doi. 10.3389/fchem.2023.1307254

By:

Akiyama, Tatsunari;
Tanaka, Yusuke;
Okamoto, Ryo;
Kajihara, Yasuhiro;
Izumi, Masayuki;
Yoshiya, Taku;
Hojo, Hironobu;
Wong, Clarence Tsun Ting

Publication type:

Article

An efficient solid-phase synthesis of peptidyl- N-acetylguanidines for use in native chemical ligation.

Published in:

Journal of Peptide Science, 2016, v. 22, n. 5, p. 343, doi. 10.1002/psc.2872

By:

Okamoto, Ryo;
Isoe, Madoka;
Izumi, Masayuki;
Kajihara, Yasuhiro

Publication type:

Article

Efficient synthesis of polypeptide-α-thioester by the method combining polypeptide expression and chemical activation for the semi-synthesis of interferon-γ having oligosaccharides.

Published in:

Journal of Peptide Science, 2014, v. 20, n. 12, p. 958, doi. 10.1002/psc.2709

By:

Kajihara, Yasuhiro;
Kanemitsu, Yurie;
Nishihara, Mika;
Okamoto, Ryo;
Izumi, Masayuki

Publication type:

Article

Safe and efficient Boc-SPPS for the synthesis of glycopeptide-α-thioesters.

Published in:

Journal of Peptide Science, 2014, v. 20, n. 2, p. 98, doi. 10.1002/psc.2608

By:

Izumi, Masayuki;
Murakami, Masumi;
Okamoto, Ryo;
Kajihara, Yasuhiro

Publication type:

Article

Risk factors and patterns of local recurrence in T3 rectal cancer treated with short-course hyperfractionated accelerated chemoradiotherapy with delayed surgery.

Published in:

2018

By:

Ryo Okamoto;
Yoshihiko Nakamoto;
Fumihiko Kimura;
Hidenori Yanagi;
Naoki Yamanaka;
Naohito Beppu;
Masataka Ikeda;
Naohiro Tomita

Publication type:

Letter to the Editor

Early results of a phase-II study of modified short-course radiotherapy combined with capecitabine and delayed surgery for T3M0 lower rectal cancer.

Published in:

2018

By:

Naohito Beppu;
Fumihiko Kimura;
Ryo Okamoto;
Yoshihiko Nakamoto;
Naohiro Tomita;
Hidenori Yanagi;
Naoki Yamanaka

Publication type:

Letter to the Editor

ANALYSIS OF AN EXPERIMENTAL QUANTUM LOGIC GATE BY COMPLEMENTARY CLASSICAL OPERATIONS.

Published in:

Modern Physics Letters A, 2006, v. 21, n. 24, p. 1837, doi. 10.1142/S0217732306021281

By:

HOFMANN, HOLGER F.;
OKAMOTO, RYO;
TAKEUCHI, SHIGEKI

Publication type:

Article

First record of Spottobrotula mahodadi Cohen & Nielsen, 1978 (Ophidiiformes, Ophidiidae) in the Straits of Malacca, Malaysia.

Published in:

Check List, 2025, v. 21, n. 2, p. 299, doi. 10.15560/21.2.299

By:

Seah, Ying Giat;
Mat Piah, Siti Asmal;
Okamoto, Ryo;
Hanafi, Norhafiz;
Izarenah, Md Repin;
Matsunuma, Mizuki

Publication type:

Article

Semisynthesis of a Post-Translationally Modified Protein by Using Chemical Cleavage and Activation of an Expressed Fusion Polypeptide.

Published in:

Chemistry - A European Journal, 2014, v. 20, n. 33, p. 10425, doi. 10.1002/chem.201403035

By:

Okamoto, Ryo;
Kimura, Motoharu;
Ishimizu, Takeshi;
Izumi, Masayuki;
Kajihara, Yasuhiro

Publication type:

Article

Homogeneous Human Complex-Type Oligosaccharides in Correctly Folded Intact Glycoproteins: Evaluation of Oligosaccharide Influence On Protein Folding, Stability, and Conformational Properties.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 19, p. 5944, doi. 10.1002/chem.201103428

By:

Kajihara, Yasuhiro;
Tanabe, Yasutaka;
Sasaoka, Shun;
Okamoto, Ryo

Publication type:

Article

Unique Self-Anhydride Formation in the Degradation of Cytidine-5′-monophosphosialic Acid (CMP-Neu5Ac) and Cytidine-5′-diphosphosialic Acid (CDP-Neu5Ac) and its Application in CMP-sialic Acid Analogue Synthesis.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 27, p. 7645, doi. 10.1002/chem.201003387

By:

Kajihara, Yasuhiro;
Nishigaki, Sachiko;
Hanzawa, Daisuke;
Nakanishi, Go;
Okamoto, Ryo;
Yamamoto, Naoki

Publication type:

Article

Harnessing Free Sulfate Groups in Glycosylation Reactions.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 4, p. 1, doi. 10.1002/anie.202416743

By:

Maki, Yuta;
Manbo, Akihiro;
Abe, Junpei;
Nobutou, Hiroki;
Hirao, Kohtaro;
Okamoto, Ryo;
Izumi, Masayuki;
Yamanaka, Shusuke;
Okumura, Mitsutaka;
Kajihara, Yasuhiro

Publication type:

Article

Uncovering a Latent Bioactive Interleukin‐6 Glycoform.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 50, p. 1, doi. 10.1002/anie.202411213

By:

Liu, Yanbo;
Maki, Yuta;
Okamoto, Ryo;
Satoh, Ayano;
Todokoro, Yasuto;
Kanemitsu, Yurie;
Otani, Keito;
Kajihara, Yasuhiro

Publication type:

Article

Efficient Synthesis of L-galactose from D-galactose.

Published in:

Journal of Carbohydrate Chemistry, 2015, v. 34, n. 9, p. 560, doi. 10.1080/07328303.2015.1115514

By:

Orii, Ryo;
Izumi, Masayuki;
Kajihara, Yasuhiro;
Okamoto, Ryo

Publication type:

Article

Implementation of a quantum controlled-SWAP gate with photonic circuits.

Published in:

Scientific Reports, 2017, p. 45353, doi. 10.1038/srep45353

By:

Ono, Takafumi;
Okamoto, Ryo;
Tanida, Masato;
Hofmann, Holger F.;
Takeuchi, Shigeki

Publication type:

Article

Experimental demonstration of a quantum shutter closing two slits simultaneously.

Published in:

Scientific Reports, 2016, p. 35161, doi. 10.1038/srep35161

By:

Okamoto, Ryo;
Takeuchi, Shigeki

Publication type:

Article

0.54 μm resolution two-photon interference with dispersion cancellation for quantum optical coherence tomography.

Published in:

Scientific Reports, 2015, p. 18042, doi. 10.1038/srep18042

By:

Okano, Masayuki;
Lim, Hwan Hong;
Okamoto, Ryo;
Nishizawa, Norihiko;
Kurimura, Sunao;
Takeuchi, Shigeki

Publication type:

Article

Harnessing Free Sulfate Groups in Glycosylation Reactions.

Published in:

Angewandte Chemie, 2025, v. 137, n. 4, p. 1, doi. 10.1002/ange.202416743

By:

Maki, Yuta;
Manbo, Akihiro;
Abe, Junpei;
Nobutou, Hiroki;
Hirao, Kohtaro;
Okamoto, Ryo;
Izumi, Masayuki;
Yamanaka, Shusuke;
Okumura, Mitsutaka;
Kajihara, Yasuhiro

Publication type:

Article

Uncovering a Latent Bioactive Interleukin‐6 Glycoform.

Published in:

Angewandte Chemie, 2024, v. 136, n. 50, p. 1, doi. 10.1002/ange.202411213

By:

Liu, Yanbo;
Maki, Yuta;
Okamoto, Ryo;
Satoh, Ayano;
Todokoro, Yasuto;
Kanemitsu, Yurie;
Otani, Keito;
Kajihara, Yasuhiro

Publication type:

Article

Chemical synthesis of homogeneous glycopeptides and glycoproteins.

Published in:

Chemical Record, 2010, v. 10, n. 2, p. 80, doi. 10.1002/tcr.200900024

By:

Kajihara, Yasuhiro;
Yamamoto, Naoki;
Okamoto, Ryo;
Hirano, Kiriko;
Murase, Takefumi

Publication type:

Article

Distinct immunity dynamics of natural killer cells in mild and moderate COVID-19 cases during the Omicron variant phase.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1594296

By:

Nishikawa, Yukari;
Yamaguchi, Kosuke;
Shofiudin, Ma'arif Athok;
Mimura, Momone;
Takata, Miyako;
Mihara, Shu;
Kawakami, Takeru;
Doi, Ayumu;
Matsuda, Risa;
Kato, Hiroyuki;
Okamoto, Ryo;
Mukuda, Kengo;
Kinoshita, Naoki;
Okada, Kensaku;
Kitaura, Tsuyoshi;
Nakamoto, Masaki;
Noma, Hisashi;
Endo, Yusuke;
Yamasaki, Akira;
Chikumi, Hiroki

Publication type:

Article

Elucidating the Function of Complex-Type Oligosaccharides by Use of Chemical Synthesis of Homogeneous Glycoproteins.

Published in:

Israel Journal of Chemistry, 2011, v. 51, n. 8/9, p. 917, doi. 10.1002/ijch.201100081

By:

Kajihara, Yasuhiro;
Izumi, Masayuki;
Hirano, Kiriko;
Murase, Takefumi;
Macmillan, Derek;
Okamoto, Ryo

Publication type:

Article

Studies in glycopeptide synthesis.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2021, v. 2021, p. 230, doi. 10.24820/ark.5550190.p011.390

By:

Yasuhiro Kajihara;
Rie Nishikawa;
Yuta Maki;
Ryo Okamoto

Publication type:

Article

Randomized trial of low-dose peginterferon α-2b plus low and escalating doses of ribavirin in older patients with chronic hepatitis C with high viral load genotype 1.

Published in:

Journal of Medical Virology, 2015, v. 87, n. 12, p. 2082, doi. 10.1002/jmv.24276

By:

Iwasaki, Yoshiaki;
Okamoto, Ryo‐ichi;
Ishii, Yasushi;
Araki, Yasuyuki;
Hashimoto, Noriaki;
Yamamoto, Kazuhide

Publication type:

Article

Randomized trial of peginterferon alpha-2b plus low and escalating dose of ribavirin in patients with chronic hepatitis C with high viral load genotype 1.

Published in:

Journal of Medical Virology, 2015, v. 87, n. 4, p. 625, doi. 10.1002/jmv.24097

By:

Iwasaki, Yoshiaki;
Araki, Yasuyuki;
Taniguchi, Hideaki;
Okamoto, Ryo‐ichi;
Kobashi, Haruhiko;
Ikeda, Fusao;
Miyake, Yasuhiro;
Takaki, Akinobu;
Yamamoto, Kazuhide

Publication type:

Article

Roadmap of incoherent digital holography.

Published in:

Applied Physics B: Lasers & Optics, 2022, v. 128, n. 11, p. 1, doi. 10.1007/s00340-022-07911-x

By:

Tahara, Tatsuki;
Zhang, Yaping;
Rosen, Joseph;
Anand, Vijayakumar;
Cao, Liangcai;
Wu, Jiachen;
Koujin, Takako;
Matsuda, Atsushi;
Ishii, Ayumi;
Kozawa, Yuichi;
Okamoto, Ryo;
Oi, Ryutaro;
Nobukawa, Teruyoshi;
Choi, Kihong;
Imbe, Masatoshi;
Poon, Ting-Chung

Publication type:

Article

An entanglement-enhanced microscope.

Published in:

Nature Communications, 2013, v. 4, n. 9, p. 2426, doi. 10.1038/ncomms3426

By:

Ono, Takafumi;
Okamoto, Ryo;
Takeuchi, Shigeki

Publication type:

Article

Downregulation of long noncoding RNA TP73-AS1 expression confers resistance to temozolomide in human glioblastoma cells.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2024, v. 43, n. 1, p. 86, doi. 10.1080/15257770.2023.2234960

By:

Ryo Okamoto;
Koki Toya;
Yoko Ogino;
Akira Sato

Publication type:

Article

Synthesis of Glc1Man9-Glycoprotein Probes by a Misfolding/Enzymatic Glucosylation/Misfolding Sequence.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 12, p. 3968, doi. 10.1002/anie.201511491

By:

Izumi, Masayuki;
Oka, Yukiho;
Okamoto, Ryo;
Seko, Akira;
Takeda, Yoichi;
Ito, Yukishige;
Kajihara, Yasuhiro

Publication type:

Article

O6-Methylguanine-DNA Methyltransferase (MGMT) as a Determinant of Resistance to Camptothecin Derivatives.

Published in:

Cancer Science, 2002, v. 93, n. 1, p. 93, doi. 10.1111/j.1349-7006.2002.tb01205.x

By:

Okamoto, Ryo;
Takano, Hiroshi;
Okamura, Tatsunori;
Park, Ji-Seon;
Tanimoto, Keiji;
Sekikawa, Takashi;
Yamamoto, Wataru;
Sparreboom, Alex;
Verweij, Jaap;
Nishiyama, Masahiko

Publication type:

Article

Regulatory Network of Mitomycin C Action in Human Colon Cancer Cells.

Published in:

Cancer Science, 1999, v. 90, n. 5, p. 571, doi. 10.1111/j.1349-7006.1999.tb00785.x

By:

Suzuki, Katsuyuki;
Yamamoto, Wataru;
Park, Ji-Seon;
Hanaoka, Hohken;
Okamoto, Ryo;
Kirihara, Yoshimasa;
Yorishima, Takashi;
Okamura, Tatsunori;
Kumazaki, Tsutomu;
Nishiyama, Masahiko

Publication type:

Article

Chemical Synthesis of a Synthetic Analogue of the Sialic Acid-Binding Lectin Siglec-7.

Published in:

ChemBioChem, 2014, v. 15, n. 17, p. 2503, doi. 10.1002/cbic.201402494

By:

Izumi, Masayuki;
Otsuki, Akihisa;
Nishihara, Mika;
Okamoto, Ryo;
Kajihara, Yasuhiro

Publication type:

Article

Efficacy and cost-effectiveness of consensus interferon monotherapy with high-dose induction for hepatitis C patients with genotype 2.

Published in:

Scandinavian Journal of Gastroenterology, 2011, v. 46, n. 1, p. 79, doi. 10.3109/00365521.2010.516449

By:

Iwasaki, Yoshiaki;
Tanaka, Hironori;
Ikeada, Hiroshi;
Okamoto, Ryo-ichi;
Araki, Yasuyuki;
Yabushita, Kazuhisa;
Kobashi, Haruhiko;
Kariyama, Kazuya;
Kawaguchi, Mitsuhiko;
Takaguchi, Kouichi;
Sakata, Tatsuro;
Ando, Masaharu;
Sakaguchi, Kohsaku;
Aoki, Noriaki;
Shiratori, Yasushi

Publication type:

Article