Works by Ohta, Kunihiro

Results: 77

The conserved histone variant H2A.Z illuminates meiotic recombination initiation.

Published in:

Current Genetics, 2018, v. 64, n. 5, p. 1015, doi. 10.1007/s00294-018-0825-9

By:

Yamada, Shintaro;
Kugou, Kazuto;
Ding, Da-Qiao;
Fujita, Yurika;
Hiraoka, Yasushi;
Murakami, Hiroshi;
Ohta, Kunihiro;
Yamada, Takatomi

Publication type:

Article

Monoclonal antibody generation by controlled immunoglobulin gene rearrangements.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07690-z

By:

Murayama, Akiho;
Matsui, Shin;
Abe, Takuya;
Kanemaki, Masato T.;
Kurosawa, Kohei;
Hirota, Kouji;
Ohta, Kunihiro;
Seo, Hidetaka

Publication type:

Article

Advantages of Mutant Generation by Genome Rearrangements of Non‐Conventional Yeast via Direct Nuclease Transfection.

Published in:

Genes to Cells, 2025, v. 30, n. 2, p. 1, doi. 10.1111/gtc.70010

By:

Oda, Arisa H.;
Yasukawa, Taishi;
Tamura, Miki;
Sano, Ayumu;
Masuo, Naohisa;
Ohta, Kunihiro

Publication type:

Article

Chromosome‐dependent aneuploid formation in Spo11‐less meiosis.

Published in:

Genes to Cells, 2023, v. 28, n. 2, p. 129, doi. 10.1111/gtc.12998

By:

Kawashima, Yuri;
Oda, Arisa H.;
Hikida, Yasushi;
Ohta, Kunihiro

Publication type:

Article

TET3 dioxygenase modulates gene conversion at the avian immunoglobulin variable region via demethylation of non‐CpG sites in pseudogene templates.

Published in:

Genes to Cells, 2021, v. 26, n. 3, p. 121, doi. 10.1111/gtc.12828

By:

Takamura, Natsuki;
Seo, Hidetaka;
Ohta, Kunihiro

Publication type:

Article

RNA decay systems enhance reciprocal switching of sense and antisense transcripts in response to glucose starvation.

Published in:

Genes to Cells, 2016, v. 21, n. 12, p. 1276, doi. 10.1111/gtc.12443

By:

Miki, Atsuko;
Galipon, Josephine;
Sawai, Satoshi;
Inada, Toshifumi;
Ohta, Kunihiro

Publication type:

Article

Extended TAQing system for large‐scale plant genome reorganization.

Published in:

Plant Journal, 2020, v. 103, n. 6, p. 2139, doi. 10.1111/tpj.14888

By:

Tanaka, Hidenori;
Muramoto, Nobuhiko;
Sugimoto, Hiroki;
Oda, Arisa H.;
Ohta, Kunihiro

Publication type:

Article

Rapid generation of specific antibodies by enhanced homologous recombination.

Published in:

Nature Biotechnology, 2005, v. 23, n. 6, p. 731, doi. 10.1038/nbt1092

By:

Seo, Hidetaka;
Masuoka, Mieko;
Murofushi, Hiromu;
Takeda, Shunichi;
Shibata, Takehiko;
Ohta, Kunihiro

Publication type:

Article

Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination.

Published in:

EMBO Journal, 1998, v. 17, n. 21, p. 6412, doi. 10.1093/emboj/17.21.6412

By:

Furuse, Munenori;
Nagase, Yuko;
Tsubouchi, Hideo;
Tsubouchi, Kimiko;
Murakami-Murofushi, Kimiko;
Shibata, Takehiko;
Ohta, Kunihiro

Publication type:

Article

In-cell Viscosity Measurement Using a Fluorescence Up-conversion Microscope.

Published in:

Chemistry Letters, 2008, v. 37, n. 12, p. 1, doi. 10.1246/cl.2008.1240

By:

Fujino, Tatsuya;
Hirota, Kouji;
Ohta, Kunihiro;
Tahara, Tahei

Publication type:

Article

Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs.

Published in:

Nature, 2008, v. 456, n. 7218, p. 130, doi. 10.1038/nature07348

By:

Hirota, Kouji;
Miyoshi, Tomoichiro;
Kugou, Kazuto;
Hoffman, Charles S.;
Shibata, Takehiko;
Ohta, Kunihiro

Publication type:

Article

lncRNA transcription induces meiotic recombination through chromatin remodelling in fission yeast.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-01798-8

By:

Senmatsu, Satoshi;
Asada, Ryuta;
Oda, Arisa;
Hoffman, Charles S.;
Ohta, Kunihiro;
Hirota, Kouji

Publication type:

Article

Acetylated Histone H3K9 is associated with meiotic recombination hotspots, and plays a role in recombination redundantly with other factors including the H3K4 methylase Set1 in fission yeast.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 6, p. 3504, doi. 10.1093/nar/gkt049

By:

Yamada, Shintaro;
Ohta, Kunihiro;
Yamada, Takatomi

Publication type:

Article

B-cell display-based one-step method to generate chimeric human IgG monoclonal antibodies.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 3, p. e14, doi. 10.1093/nar/gkq1122

By:

Lin, Waka;
Kurosawa, Kohei;
Murayama, Akiho;
Kagaya, Eri;
Ohta, Kunihiro

Publication type:

Article

Structural and functional analyses of the DMC1-M200V polymorphism found in the human population.

Published in:

Nucleic Acids Research, 2008, v. 36, n. 12, p. 4181, doi. 10.1093/nar/gkn362

By:

Hikiba, Juri;
Hirota, Kouji;
Kagawa, Wataru;
Ikawa, Shukuko;
Kinebuchi, Takashi;
Sakane, Isao;
Takizawa, Yoshimasa;
Yokoyama, Shigeyuki;
Mandon-Pépin, Béatrice;
Nicolas, Alain;
Shibata, Takehiko;
Ohta, Kunihiro;
Kurumizaka, Hitoshi

Publication type:

Article

Targeted induction of meiotic double-strand breaks reveals chromosomal domain-dependent regulation of Spo11 and interactions among potential sites of meiotic recombination.

Published in:

Nucleic Acids Research, 2008, v. 36, n. 3, p. 984, doi. 10.1093/nar/gkm1082

By:

Fukuda, Tomoyuki;
Kugou, Kazuto;
Sasanuma, Hiroyuki;
Shibata, Takehiko;
Ohta, Kunihiro

Publication type:

Article

Actin-related protein Arp4 functions in kinetochore assembly.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 9, p. 3109, doi. 10.1093/nar/gkm161

By:

Ogiwara, Hideaki;
Ui, Ayako;
Kawashima, Satoshi;
Kugou, Kazuto;
Onoda, Fumitoshi;
Iwahashi, Hitoshi;
Harata, Masahiko;
Ohta, Kunihiro;
Enomoto, Takemi;
Seki, Masayuki

Publication type:

Article

Meiotic association between Spo11 regulated by Rec102, Rec104 and Rec114.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 4, p. 1119, doi. 10.1093/nar/gkl1162

By:

Sasanuma, Hiroyuki;
Murakami, Hajime;
Fukuda, Tomoyuki;
Shibata, Takehiko;
Nicolas, Alain;
Ohta, Kunihiro

Publication type:

Article

Fission yeast global repressors regulate the specificity of chromatin alteration in response to distinct environmental stresses.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 2, p. 855, doi. 10.1093/nar/gkh251

By:

Hirota, Kouji;
Hasemi, Tomoko;
Yamada, Takatomi;
Mizuno, Ken‐ich;
Hoffman, Charles S.;
Shibata, Takehiko;
Ohta, Kunihiro

Publication type:

Article

Correlation between premeiotic DNA replication and chromatin transition at yeast recombination initiation sites.

Published in:

Nucleic Acids Research, 2003, v. 31, n. 14, p. 4085, doi. 10.1093/nar/gkg441

By:

Murakami, Hajime;
Borde, Valerie;
Shibata, Takehiko;
Lichten, Michael;
Ohta, Kunihiro

Publication type:

Article

Role of non-coding RNA transcription around gene regulatory elements in transcription factor recruitment.

Published in:

RNA Biology, 2017, v. 14, n. 1, p. 1, doi. 10.1080/15476286.2016.1248020

By:

Takemata, Naomichi;
Ohta, Kunihiro

Publication type:

Article

Relationship between G+C content, ORF-length and mRNA concentration in Saccharomyces cerevisiae.

Published in:

Yeast, 2003, v. 20, n. 8, p. 703, doi. 10.1002/yea.992

By:

Antonio Marín;
Mercedes Gallardo;
Yuki Kato;
Katsuhiko Shirahige;
Gabriel Gutiérrez;
Kunihiro Ohta;
Andrés Aguilera

Publication type:

Article

Actin-Related Protein Arp6 Influences H2A.Z-Dependent and -Independent Gene Expression and Links Ribosomal Protein Genes to Nuclear Pores.

Published in:

PLoS Genetics, 2010, v. 6, n. 4, p. 1, doi. 10.1371/journal.pgen.1000910

By:

Yoshida, Takahito;
Shimada, Kenji;
Oma, Yukako;
Kalck, Véronique;
Akimura, Kazumi;
Taddei, Angela;
Iwahashi, Hitoshi;
Kugou, Kazuto;
Ohta, Kunihiro;
Gasser, Susan M.;
Harata, Masahiko

Publication type:

Article

Fission Yeast TORC1 Promotes Cell Proliferation through Sfp1, a Transcription Factor Involved in Ribosome Biogenesis.

Published in:

Molecular & Cellular Biology, 2023, v. 43, n. 12, p. 675, doi. 10.1080/10985549.2023.2282349

By:

Tai, Yen Teng;
Fukuda, Tomoyuki;
Morozumi, Yuichi;
Hirai, Hayato;
Oda, Arisa H.;
Kamada, Yoshiaki;
Akikusa, Yutaka;
Kanki, Tomotake;
Ohta, Kunihiro;
Shiozaki, Kazuhiro

Publication type:

Article

Gene mapping methodology powered by induced genome rearrangements.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-20999-7

By:

Yone, Hideyuki;
Kono, Hiromitsu;
Hirai, Hayato;
Ohta, Kunihiro

Publication type:

Article

Imputation-free reconstructions of three-dimensional chromosome architectures in human diploid single-cells using allele-specified contacts.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-15038-4

By:

Hirata, Yoshito;
Oda, Arisa H.;
Motono, Chie;
Shiro, Masanori;
Ohta, Kunihiro

Publication type:

Article

Imputation-free reconstructions of three-dimensional chromosome architectures in human diploid single-cells using allele-specified contacts.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-15038-4

By:

Hirata, Yoshito;
Oda, Arisa H.;
Motono, Chie;
Shiro, Masanori;
Ohta, Kunihiro

Publication type:

Article

B Cell-Based Seamless Engineering of Antibody Fc Domains.

Published in:

PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0167232

By:

Hashimoto, Koji;
Kurosawa, Kohei;
Murayama, Akiho;
Seo, Hidetaka;
Ohta, Kunihiro

Publication type:

Article

Conditional genomic rearrangement by designed meiotic recombination using VDE (PI-SceI) in yeast.

Published in:

Molecular Genetics & Genomics, 2007, v. 278, n. 4, p. 467, doi. 10.1007/s00438-007-0264-7

By:

Tomoyuki Fukuda;
Yoshikazu Ohya;
Kunihiro Ohta

Publication type:

Article

TAQing2.0 for genome reorganization of asexual industrial yeasts by direct protein transfection.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03093-6

By:

Yasukawa, Taishi;
Oda, Arisa H.;
Nakamura, Takahiro;
Masuo, Naohisa;
Tamura, Miki;
Yamasaki, Yuriko;
Imura, Makoto;
Yamada, Takatomi;
Ohta, Kunihiro

Publication type:

Article

Transcription of mRNA-type long non-coding RNAs (mlonRNAs) disrupts chromatin array.

Published in:

Communicative & Integrative Biology, 2009, v. 2, n. 1, p. 25, doi. 10.4161/cib.2.1.7378

By:

Hirota, Kouji;
Ohta, Kunihiro

Publication type:

Article

Sutureless microvascular anastomosis assisted by an expandable shape-memory alloy stent.

Published in:

PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0181520

By:

Saegusa, Noriko;
Sarukawa, Shunji;
Ohta, Kunihiro;
Takamatsu, Kensuke;
Watanabe, Mitsuhiro;
Sugino, Takashi;
Nakagawa, Masahiro;
Akiyama, Yasuto;
Kusuhara, Masatoshi;
Kishi, Kazuo;
Inoue, Keita

Publication type:

Article

Essential roles of Snf21, a Swi2/Snf2 family chromatin remodeler, in fission yeast mitosis.

Published in:

Genes & Genetic Systems, 2008, v. 83, n. 5, p. 361, doi. 10.1266/ggs.83.361

By:

Yamada, Kentaro;
Hirota, Kouji;
Mizuno, Ken-ichi;
Shibata, Takehiko;
Ohta, Kunihiro

Publication type:

Article

Intestinal absorption and analgesic activity of aminopeptidase-resistant cellobiose-coupled leucine enkephalinamide.

Published in:

Biopharmaceutics & Drug Disposition, 1998, v. 19, n. 9, p. 605, doi. 10.1002/(SICI)1099-081X(199812)19:9<605::AID-BDD149>3.0.CO;2-W

By:

Mizuma, Takashi;
Ohta, Kunihiro;
Awazu, Shoji

Publication type:

Article

Competitive inactivation of a double‐strand DNA break site involves parallel suppression of meiosis‐induced changes in chromatin configuration.

Published in:

Nucleic Acids Research, 1999, v. 27, n. 10, p. 2175, doi. 10.1093/nar/27.10.2175

By:

Ohta, Kunihiro;
Wu, Tzu‐Chen;
Lichten, Michael;
Shibata, Takehiko

Publication type:

Article

Analysis of novel Sir3 binding regions in Saccharomyces cerevisiae.

Published in:

Journal of Biochemistry, 2016, v. 160, n. 1, p. 11, doi. 10.1093/jb/mvw021

By:

Risa Mitsumori;
Tomoe Ohashi;
Kazuto Kugou;
Ayako Ichino;
Kei Taniguchi;
Kunihiro Ohta;
Hiroyuki Uchida;
Masaya Oki

Publication type:

Article

Initiation of meiotic recombination in chromatin structure.

Published in:

Journal of Biochemistry, 2013, v. 154, n. 2, p. 107, doi. 10.1093/jb/mvt054

By:

Yamada, Takatomi;
Ohta, Kunihiro

Publication type:

Article

Distinct roles of HDAC1 and HDAC2 in transcription and recombination at the immunoglobulin loci in the chicken B cell line DT40.

Published in:

Journal of Biochemistry, 2010, v. 148, n. 2, p. 201, doi. 10.1093/jb/mvq054

By:

Kohei Kurosawa;
Waka Lin;
Kunihiro Ohta

Publication type:

Article

Histone Chaperone Asf1 Is Required for the Establishment of Repressive Chromatin in Schizosaccharomyces pombe fbp1Gene Repression.

Published in:

Molecular & Cellular Biology, 2018, v. 38, n. 18, p. 1, doi. 10.1128/MCB.00194-18

By:

Umeda, Miki;
Chiaki Tsunekawa;
Satoshi Senmatsu;
Ryuta Asada;
Takuya Abe;
Kunihiro Ohta;
Hoffman, Charles S.;
Kouji Hirota

Publication type:

Article

Antagonistic Controls of Chromatin and mRNA Start Site Selection by Tup Family Corepressors and the CCAAT-Binding Factor.

Published in:

Molecular & Cellular Biology, 2015, v. 35, n. 5, p. 847, doi. 10.1128/MCB.00924-14

By:

Ryuta Asada;
Naomichi Takemata;
Hoffman, Charles S.;
Kunihiro Ohta;
Kouji Hirota

Publication type:

Article

Ctp1[supCtIP] and Rad32[supMre11] Nuclease Activity Are Required for Rec12[supSpo11] Removal, but Rec12[supSpo11] Removal Is Dispensable for Other MRN-Dependent Meiotic Functions.

Published in:

2009

By:

Hartsuiker, Edgar;
Mizuno, Kenichi;
Molnar, Monika;
Juerg Kohli;
Ohta, Kunihiro;
Carr, Antony M.

Publication type:

Abstract

Molecular Characterization of the Role of the Schizosaccharomyces pombe nip1<sup>+</sup>/ctp1<sup>+</sup> Gene in DNA Double-Strand Break Repair in Association with the Mre11-Rad50-Nbs1 Complex.

Published in:

2008

By:

Akamatsu, Yufuko;
Murayama, Yasuto;
Yamada, Takatomi;
Nakazaki, Tomofumi;
Tsutsui, Yasuhiro;
Ohta, Kunihiro;
Iwasaki, Hiroshi

Publication type:

Abstract

lncRNA transcriptional initiation induces chromatin remodeling within a limited range in the fission yeast fbp1 promoter.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-36049-0

By:

Senmatsu, Satoshi;
Asada, Ryuta;
Abe, Takuya;
Hoffman, Charles S.;
Ohta, Kunihiro;
Hirota, Kouji

Publication type:

Article

Comparative Research: Regulatory Mechanisms of Ribosomal Gene Transcription in Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 2, p. 288, doi. 10.3390/biom13020288

By:

Hirai, Hayato;
Ohta, Kunihiro

Publication type:

Article

Molecular mechanisms of avian immunoglobulin gene diversification and prospect for industrial applications.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1453833

By:

Hidetaka Seo;
Kouji Hirota;
Kunihiro Ohta

Publication type:

Article

Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.

Published in:

International Immunology, 2008, v. 20, n. 2, p. 277, doi. 10.1093/intimm/dxm140

By:

Hiroyuki Kitao;
Masayo Kimura;
Kazuhiko Yamamoto;
Hidetaka Seo;
Keiko Namikoshi;
Yasutoshi Agata;
Kunihiro Ohta;
Minoru Takata

Publication type:

Article

Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing.

Published in:

Nature Communications, 2016, v. 7, n. 1, p. 10393, doi. 10.1038/ncomms10393

By:

Tashiro, Sanki;
Handa, Tetsuya;
Matsuda, Atsushi;
Ban, Takuto;
Takigawa, Toru;
Miyasato, Kazumi;
Ishii, Kojiro;
Kugou, Kazuto;
Ohta, Kunihiro;
Hiraoka, Yasushi;
Masukata, Hisao;
Kanoh, Junko

Publication type:

Article

Light-controlled Spo11-less meiotic DNA breaks by MagTAQing lead to chromosomal aberrations Open Access.

Published in:

Nucleic Acids Research, 2025, v. 53, n. 7, p. 1, doi. 10.1093/nar/gkaf206

By:

Yone, Hideyuki;
Kawashima, Yuri;
Hirai, Hayato;
Oda, Arisa H;
Sato, Moritoshi;
Kono, Hiromitsu;
Ohta, Kunihiro

Publication type:

Article

Facultative heterochromatin formation in rDNA is essential for cell survival during nutritional starvation.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 7, p. 3727, doi. 10.1093/nar/gkac175

By:

Hirai, Hayato;
Takemata, Naomichi;
Tamura, Miki;
Ohta, Kunihiro

Publication type:

Article

Conserved HORMA domain-containing protein Hop1 stabilizes interaction between proteins of meiotic DNA break hotspots and chromosome axis.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 19, p. 10166, doi. 10.1093/nar/gkz754

By:

Kariyazono, Ryo;
Oda, Arisa;
Yamada, Takatomi;
Ohta, Kunihiro

Publication type:

Article