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Targeted Protein Degradation by Chimeric Compounds using Hydrophobic E3 Ligands and Adamantane Moiety.
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- Pharmaceuticals (14248247), 2020, v. 13, n. 3, p. 34, doi. 10.3390/ph13030034
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- Article
TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death.
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- EMBO Journal, 2005, v. 24, n. 6, p. 1243, doi. 10.1038/sj.emboj.7600596
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- Article
Peptide Stapling Improves the Sustainability of a Peptide-Based Chimeric Molecule That Induces Targeted Protein Degradation.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 16, p. 8772, doi. 10.3390/ijms22168772
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- Article
Development of a Cell-penetrating Peptide that Exhibits Responsive Changes in its Secondary Structure in the Cellular Environment.
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- Scientific Reports, 2016, p. 33003, doi. 10.1038/srep33003
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- Article
Development of Rapid and Facile Solid‐Phase Synthesis of PROTACs via a Variety of Binding Styles.
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- ChemistryOpen, 2022, v. 11, n. 7, p. 1, doi. 10.1002/open.202200131
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- Article
C/EBP family transcription factors are degraded by the proteasome but stabilized by forming dimer.
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- Oncogene, 2003, v. 22, n. 9, p. 1273, doi. 10.1038/sj.onc.1206204
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- Article
Structure–activity relationship study of amphipathic antimicrobial peptides using helix‐destabilizing sarcosine.
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- Journal of Peptide Science, 2021, v. 27, n. 12, p. 1, doi. 10.1002/psc.3360
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- Article
The deubiquitinating enzyme USP17 regulates c‐Myc levels and controls cell proliferation and glycolysis.
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- FEBS Letters, 2022, v. 596, n. 4, p. 465, doi. 10.1002/1873-3468.14296
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- Article
Anti-Inflammatory Activity of Kurarinone Involves Induction of HO-1 via the KEAP1/Nrf2 Pathway.
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- Antioxidants, 2020, v. 9, n. 9, p. 842, doi. 10.3390/antiox9090842
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- Article
Periplocin and cardiac glycosides suppress the unfolded protein response.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-89074-x
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- Article
Transcriptional Coactivator TAZ Negatively Regulates Tumor Suppressor p53 Activity and Cellular Senescence.
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- Cells (2073-4409), 2020, v. 9, n. 1, p. 1, doi. 10.3390/cells9010171
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- Article
The CDK inhibitor p21 is a novel target gene of ATF4 and contributes to cell survival under ER stress.
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- FEBS Letters, 2017, v. 591, n. 21, p. 3682, doi. 10.1002/1873-3468.12869
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- Article
Specific degradation of CRABP-II via cIAP1-mediated ubiquitylation induced by hybrid molecules that crosslink cIAP1 and the target protein
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- FEBS Letters, 2011, v. 585, n. 8, p. 1147, doi. 10.1016/j.febslet.2011.03.019
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- Article
Kurarinone from Sophora Flavescens Roots Triggers ATF4 Activation and Cytostatic Effects Through PERK Phosphorylation.
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- Molecules, 2019, v. 24, n. 17, p. 3110, doi. 10.3390/molecules24173110
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- Article
Anti-Tumorigenic Activity of Chrysin from Oroxylum indicum via Non-Genotoxic p53 Activation through the ATM-Chk2 Pathway.
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- Molecules, 2018, v. 23, n. 6, p. 1394, doi. 10.3390/molecules23061394
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- Article
Pharmacological difference between degrader and inhibitor against oncogenic BCR-ABL kinase.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31913-5
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- Article
Proteasome inhibitors prevent cell death and prolong survival of mice challenged by Shiga toxin.
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- FEBS Open Bio, 2015, v. 5, p. 605, doi. 10.1016/j.fob.2015.06.005
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- Article
C/EBP homologous protein (CHOP) up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform
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- FEBS Letters, 2003, v. 541, n. 1-3, p. 33, doi. 10.1016/S0014-5793(03)00283-7
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- Article
Development of a potent small‐molecule degrader against oncogenic BRAF<sup>V600E</sup> protein that evades paradoxical MAPK activation.
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- Cancer Science, 2022, v. 113, n. 8, p. 2828, doi. 10.1111/cas.15401
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- Article
Development of protein degradation inducers of oncogenic BCR- ABL protein by conjugation of ABL kinase inhibitors and IAP ligands.
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- Cancer Science, 2017, v. 108, n. 8, p. 1657, doi. 10.1111/cas.13284
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- Article
SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib.
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- Cancer Science, 2017, v. 108, n. 5, p. 1032, doi. 10.1111/cas.13198
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- Article
Development of hybrid small molecules that induce degradation of estrogen receptor-alpha and necrotic cell death in breast cancer cells.
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- Cancer Science, 2013, v. 104, n. 11, p. 1492, doi. 10.1111/cas.12272
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- Article
Modulation of RIP1 ubiquitylation and distribution by MeBS to sensitize cancer cells to tumor necrosis factor α-induced apoptosis.
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- Cancer Science, 2010, v. 101, n. 11, p. 2425, doi. 10.1111/j.1349-7006.2010.01697.x
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- Article