Works matching AU Ogungbenro, Kayode

Results: 59

Publisher Correction: Simultaneous Estimation of fm and FG Values Directly from Clinical Drug-Drug Interaction Study Data.

Published in:

2025

By:

Cleary, Yumi;
Milani, Nicolo;
Ogungbenro, Kayode;
Aarons, Leon;
Galetin, Aleksandra;
Gertz, Michael

Publication type:

Correction Notice

Simultaneous Estimation of fm and F<sub>G</sub> Values Directly from Clinical Drug-Drug Interaction Study Data.

Published in:

AAPS Journal, 2025, v. 27, n. 4, p. 1, doi. 10.1208/s12248-025-01064-3

By:

Cleary, Yumi;
Milani, Nicolo;
Ogungbenro, Kayode;
Aarons, Leon;
Galetin, Aleksandra;
Gertz, Michael

Publication type:

Article

A population pharmacokinetic model for simvastatin and its metabolites in children and adolescents.

Published in:

European Journal of Clinical Pharmacology, 2019, v. 75, n. 9, p. 1227, doi. 10.1007/s00228-019-02697-y

By:

Ogungbenro, Kayode;
Wagner, Jonathan B.;
Abdel-Rahman, Susan;
Leeder, J. Steven;
Galetin, Aleksandra

Publication type:

Article

How many subjects are necessary for population pharmacokinetic experiments? Confidence interval approach.

Published in:

European Journal of Clinical Pharmacology, 2008, v. 64, n. 7, p. 705, doi. 10.1007/s00228-008-0493-7

By:

Ogungbenro, Kayode;
Aarons, Leon

Publication type:

Article

Does "Birth" as an Event Impact Maturation Trajectory of Renal Clearance via Glomerular Filtration? Reexamining Data in Preterm and Full‐Term Neonates by Avoiding the Creatinine Bias.

Published in:

Journal of Clinical Pharmacology, 2021, v. 61, n. 2, p. 159, doi. 10.1002/jcph.1725

By:

Salem, Farzaneh;
Johnson, Trevor N.;
Hodgkinson, Arran B. J.;
Ogungbenro, Kayode;
Rostami‐Hodjegan, Amin

Publication type:

Article

Reduction of inflammation after administration of interleukin-1 receptor antagonist following aneurysmal subarachnoid hemorrhage: results of the Subcutaneous Interleukin-IRa in SAH (SCIL-SAH) study.

Published in:

Journal of Neurosurgery, 2018, v. 128, n. 2, p. 515, doi. 10.3171/2016.9.JNS16615

By:

Galea, James;
Ogungbenro, Kayode;
Hulme, Sharon;
Patel, Hiren;
Scarth, Sylvia;
Hoadley, Margaret;
Illingworth, Karen;
McMahon, Catherine J.;
Tzerakis, Nikolaos;
King, Andrew T.;
Vail, Andy;
Hopkins, Stephen J.;
Rothwell, Nancy;
Tyrrell, Pippa

Publication type:

Article

Sample Size Calculations Based on Generalized Estimating Equations for Population Pharmacokinetic Experiments.

Published in:

Journal of Biopharmaceutical Statistics, 2006, v. 16, n. 2, p. 135, doi. 10.1080/10543400500508705

By:

Ogungbenro, Kayode;
Aarons, Leon;
Graham, Gordon

Publication type:

Article

Mixed effects modeling of radiotherapy in combination with immune checkpoint blockade or inhibitors of the DNA damage response pathway.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 11, p. 1640, doi. 10.1002/psp4.13026

By:

Hodson, David;
Mistry, Hitesh;
Guzzetti, Sofia;
Davies, Michael;
Staniszewska, Anna;
Farrington, Paul;
Cadogan, Elaine;
Yates, James;
Aarons, Leon;
Ogungbenro, Kayode

Publication type:

Article

A "middle‐out approach" for the prediction of human drug disposition from preclinical data using simplified physiologically based pharmacokinetic (PBPK) models.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 3, p. 346, doi. 10.1002/psp4.12915

By:

Yau, Estelle;
Gertz, Michael;
Ogungbenro, Kayode;
Aarons, Leon;
Olivares‐Morales, Andrés

Publication type:

Article

Investigation of simplified physiologically‐based pharmacokinetic models in rat and human.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 3, p. 333, doi. 10.1002/psp4.12911

By:

Yau, Estelle;
Olivares‐Morales, Andrés;
Ogungbenro, Kayode;
Aarons, Leon;
Gertz, Michael

Publication type:

Article

Population pharmacokinetic modeling and simulation to support qualification of pyridoxic acid as endogenous biomarker of OAT1/3 renal transporters.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 5, p. 467, doi. 10.1002/psp4.12610

By:

Ahmad, Amais;
Ogungbenro, Kayode;
Kunze, Annett;
Jacobs, Frank;
Snoeys, Jan;
Rostami‐Hodjegan, Amin;
Galetin, Aleksandra

Publication type:

Article

PBPK Model of Coproporphyrin I: Evaluation of the Impact of SLCO1B1 Genotype, Ethnicity, and Sex on its Inter‐Individual Variability.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 2, p. 137, doi. 10.1002/psp4.12582

By:

Takita, Hiroyuki;
Barnett, Shelby;
Zhang, Yueping;
Ménochet, Karelle;
Shen, Hong;
Ogungbenro, Kayode;
Galetin, Aleksandra

Publication type:

Article

Covariates in population pharmacokinetic studies of critically ill adults receiving β-lactam antimicrobials: a systematic review and narrative synthesis.

Published in:

JAC-Antimicrobial Resistance, 2024, v. 6, n. 1, p. 1, doi. 10.1093/jacamr/dlae030

By:

Hansel, Jan;
Mannan, Fahmida;
Robey, Rebecca;
Kumarendran, Mary;
Bladon, Siân;
Mathioudakis, Alexander G;
Ogungbenro, Kayode;
Dark, Paul;
Felton, Timothy W

Publication type:

Article

A study of the dosage and duration for levobupivacaine infusion by the caudal‐epidural route in infants aged 3‐6 months.

Published in:

Pediatric Anesthesia, 2019, v. 29, n. 2, p. 161, doi. 10.1111/pan.13548

By:

Vashisht, Rita;
Bendon, Anju A.;
Okonkwo, Ijeoma;
Patel, Davandra;
Fullwood, Catherine;
Ogungbenro, Kayode;
Aarons, Leon;
Darwich, Adam S.;
Anderson, Brian

Publication type:

Article

Study design and population pharmacokinetic analysis of a phase II dose-ranging study of interleukin-1 receptor antagonist.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2016, v. 43, n. 1, p. 1, doi. 10.1007/s10928-015-9450-0

By:

Galea, James;
Ogungbenro, Kayode;
Hulme, Sharon;
Hopkins, Stephen;
Tyrrell, Pippa;
Rothwell, Nancy

Publication type:

Article

Application of a Bayesian approach to physiological modelling of mavoglurant population pharmacokinetics.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2015, v. 42, n. 6, p. 639, doi. 10.1007/s10928-015-9430-4

By:

Wendling, Thierry;
Dumitras, Swati;
Ogungbenro, Kayode;
Aarons, Leon

Publication type:

Article

Physiologically based pharmacokinetic modelling of methotrexate and 6-mercaptopurine in adults and children. Part 2: 6-mercaptopurine and its interaction with methotrexate.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2014, v. 41, n. 2, p. 173, doi. 10.1007/s10928-014-9355-3

By:

Ogungbenro, Kayode;
Aarons, Leon

Publication type:

Article

Physiologically based pharmacokinetic modelling of methotrexate and 6-mercaptopurine in adults and children. Part 1: methotrexate.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2014, v. 41, n. 2, p. 159, doi. 10.1007/s10928-014-9354-4

By:

Ogungbenro, Kayode;
Aarons, Leon

Publication type:

Article

Population Fisher information matrix and optimal design of discrete data responses in population pharmacodynamic experiments.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2011, v. 38, n. 4, p. 449, doi. 10.1007/s10928-011-9203-7

By:

Ogungbenro, Kayode;
Aarons, Leon

Publication type:

Article

Structural identifiability analysis of pharmacokinetic models using DAISY: semi-mechanistic gastric emptying models for C-octanoic acid.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2011, v. 38, n. 2, p. 279, doi. 10.1007/s10928-011-9193-5

By:

Ogungbenro, Kayode;
Aarons, Leon

Publication type:

Article

Sample size/power calculations for repeated ordinal measurements in population pharmacodynamic experiments.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2010, v. 37, n. 1, p. 67, doi. 10.1007/s10928-009-9144-6

By:

Kayode Ogungbenro;
Leon Aarons

Publication type:

Article

Optimisation of sampling windows design for population pharmacokinetic experiments.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2008, v. 35, n. 4, p. 465, doi. 10.1007/s10928-008-9097-1

By:

Kayode Ogungbenro;
Leon Aarons

Publication type:

Article

Optimal Design for Multiresponse Pharmacokinetic–Pharmacodynamic Models – Dealing with Unbalanced Designs.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2007, v. 34, n. 3, p. 313, doi. 10.1007/s10928-006-9048-7

By:

Kayode Ogungbenro;
Ivelina Gueorguieva;
Oneeb Majid;
Gordon Graham;
Leon Aarons

Publication type:

Article

Impact of tumour size measurement inter-operator variability on model-based drug effect evaluation.

Published in:

2020

By:

Lombard, Aurélie;
Mistry, Hitesh;
Chapman, Sonya C.;
Gueoguieva, Ivelina;
Aarons, Leon;
Ogungbenro, Kayode

Publication type:

journal article

Predicting survival of pancreatic cancer patients treated with gemcitabine using longitudinal tumour size data.

Published in:

2016

By:

Wendling, Thierry;
Mistry, Hitesh;
Ogungbenro, Kayode;
Aarons, Leon

Publication type:

journal article

Population Pharmacokinetics of Imatinib in Nigerians With Chronic Myeloid Leukemia: Clinical Implications for Dosing and Resistance.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1554, doi. 10.1002/jcph.953

By:

Adeagbo, Babatunde Ayodeji;
Olugbade, Tiwalade Adewale;
Durosinmi, Muheez Alani;
Bolarinwa, Rahman Ayodele;
Ogungbenro, Kayode;
Bolaji, Oluseye Oladotun

Publication type:

Article

Precision criteria to derive sample size when designing pediatric pharmacokinetic studies: Which measure of variability should be used?

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 3, p. 311, doi. 10.1002/jcph.206

By:

Salem, Farzaneh;
Ogungbenro, Kayode;
Vajjah, Pavan;
Johnson, Trevor N.;
Aarons, Leon;
Rostami‐Hodjegan, Amin

Publication type:

Article

Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: results of a dose-ranging study.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2011, v. 31, n. 2, p. 439, doi. 10.1038/jcbfm.2010.103

By:

Galea, James;
Ogungbenro, Kayode;
Hulme, Sharon;
Greenhalgh, Andrew;
Aarons, Leon;
Scarth, Sylvia;
Hutchinson, Peter;
Grainger, Samantha;
King, Andrew;
Hopkins, Stephen J;
Rothwell, Nancy;
Tyrrell, Pippa

Publication type:

Article

Sample Size/Power Calculations for Population Pharmacodynamic Experiments Involving Repeated-Count Measurements.

Published in:

Journal of Biopharmaceutical Statistics, 2010, v. 20, n. 5, p. 1026, doi. 10.1080/10543401003619205

By:

Ogungbenro, Kayode;
Aarons, Leon

Publication type:

Article

An Effective Approach for Obtaining Optimal Sampling Windows for Population Pharmacokinetic Experiments.

Published in:

Journal of Biopharmaceutical Statistics, 2009, v. 19, n. 1, p. 174, doi. 10.1080/10543400802536131

By:

Ogungbenro, Kayode;
Aarons, Leon

Publication type:

Article

Sample Size Calculations for Population Pharmacodynamic Experiments Involving Repeated Dichotomous Observations.

Published in:

Journal of Biopharmaceutical Statistics, 2008, v. 18, n. 6, p. 1212, doi. 10.1080/10543400802375845

By:

Ogungbenro, Kayode;
Aarons, Leon

Publication type:

Article

Incorporating Correlation in Interindividual Variability for the Optimal Design of Multiresponse Pharmacokinetic Experiments.

Published in:

Journal of Biopharmaceutical Statistics, 2008, v. 18, n. 2, p. 342, doi. 10.1080/10543400701697208

By:

Ogungbenro, Kayode;
Graham, Gordon;
Gueorguieva, Ivelina;
Aarons, Leon

Publication type:

Article

Sample-size calculations for multi-group comparison in population pharmacokinetic experiments.

Published in:

Pharmaceutical Statistics, 2010, v. 9, n. 4, p. 255, doi. 10.1002/pst.388

By:

Ogungbenro, Kayode;
Aarons, Leon

Publication type:

Article

Application of optimal design methodologies in clinical pharmacology experiments.

Published in:

Pharmaceutical Statistics, 2009, v. 8, n. 3, p. 239, doi. 10.1002/pst.354

By:

Ogungbenro, Kayode;
Dokoumetzidis, Aristides;
Aarons, Leon

Publication type:

Article

Impact of Hepatic CYP3A4 Ontogeny Functions on Drug–Drug Interaction Risk in Pediatric Physiologically‐Based Pharmacokinetic/Pharmacodynamic Modeling: Critical Literature Review and Ivabradine Case Study.

Published in:

Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1618, doi. 10.1002/cpt.2134

By:

Lang, Jennifer;
Vincent, Ludwig;
Chenel, Marylore;
Ogungbenro, Kayode;
Galetin, Aleksandra

Publication type:

Article

Gaining Mechanistic Insight Into Coproporphyrin I as Endogenous Biomarker for OATP1B‐Mediated Drug–Drug Interactions Using Population Pharmacokinetic Modeling and Simulation.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 3, p. 564, doi. 10.1002/cpt.983

By:

Barnett, Shelby;
Ogungbenro, Kayode;
Galetin, Aleksandra;
Ménochet, Karelle;
Shen, Hong;
Humphreys, W. Griffith;
Lai, Yurong

Publication type:

Article

Dose Rationalization of Pembrolizumab and Nivolumab Using Pharmacokinetic Modeling and Simulation and Cost Analysis.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 103, n. 4, p. 582, doi. 10.1002/cpt.875

By:

Ogungbenro, Kayode;
Patel, Alkesh;
Duncombe, Robert;
Nuttall, Richard;
Clark, James;
Lorigan, Paul

Publication type:

Article

Dose individualisation in oncology using chemotherapy‐induced neutropenia: Example of docetaxel in non‐small cell lung cancer patients.

Published in:

British Journal of Clinical Pharmacology, 2021, v. 87, n. 4, p. 2053, doi. 10.1111/bcp.14614

By:

Lombard, Aurélie;
Mistry, Hitesh;
Aarons, Leon;
Ogungbenro, Kayode

Publication type:

Article

Physiologically based pharmacokinetic model for 6-mercpatopurine: exploring the role of genetic polymorphism in TPMT enzyme activity.

Published in:

British Journal of Clinical Pharmacology, 2015, v. 80, n. 1, p. 86, doi. 10.1111/bcp.12588

By:

Ogungbenro, Kayode;
Aarons, Leon

Publication type:

Article

The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors.

Published in:

British Journal of Clinical Pharmacology, 2012, v. 73, n. 1, p. 66, doi. 10.1111/j.1365-2125.2011.04051.x

By:

Lane, Steven;
Al-Zubiedi, Sameh;
Hatch, Ellen;
Matthews, Ivan;
Jorgensen, Andrea L.;
Deloukas, Panos;
Daly, Ann K.;
Park, B. Kevin;
Aarons, Leon;
Ogungbenro, Kayode;
Kamali, Farhad;
Hughes, Dyfrig;
Pirmohamed, Munir

Publication type:

Article

Population pharmacokinetics and optimal design of paediatric studies for famciclovir.

Published in:

British Journal of Clinical Pharmacology, 2009, v. 68, n. 4, p. 546, doi. 10.1111/j.1365-2125.2009.03479.x

By:

Ogungbenro, Kayode;
Matthews, Ivan;
Looby, Michael;
Kaiser, Guenther;
Graham, Gordon;
Aarons, Leon

Publication type:

Article

In Vitro to In Vivo Extrapolation Linked to Physiologically Based Pharmacokinetic Models for Assessing the Brain Drug Disposition.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00675-w

By:

Murata, Yukiko;
Neuhoff, Sibylle;
Rostami-Hodjegan, Amin;
Takita, Hiroyuki;
Al-Majdoub, Zubida M.;
Ogungbenro, Kayode

Publication type:

Article

Simultaneous Ivabradine Parent-Metabolite PBPK/PD Modelling Using a Bayesian Estimation Method.

Published in:

AAPS Journal, 2020, v. 22, n. 6, p. N.PAG, doi. 10.1208/s12248-020-00502-8

By:

Lang, Jennifer;
Vincent, Ludwig;
Chenel, Marylore;
Ogungbenro, Kayode;
Galetin, Aleksandra

Publication type:

Article

Global Sensitivity Analysis of the Rodgers and Rowland Model for Prediction of Tissue: Plasma Partitioning Coefficients: Assessment of the Key Physiological and Physicochemical Factors That Determine Small-Molecule Tissue Distribution.

Published in:

AAPS Journal, 2020, v. 22, n. 2, p. 1, doi. 10.1208/s12248-020-0418-7

By:

Yau, Estelle;
Olivares-Morales, Andrés;
Gertz, Michael;
Parrott, Neil;
Darwich, Adam S.;
Aarons, Leon;
Ogungbenro, Kayode

Publication type:

Article

Reduction of a Whole-Body Physiologically Based Pharmacokinetic Model to Stabilise the Bayesian Analysis of Clinical Data.

Published in:

AAPS Journal, 2016, v. 18, n. 1, p. 196, doi. 10.1208/s12248-015-9840-7

By:

Wendling, Thierry;
Tsamandouras, Nikolaos;
Dumitras, Swati;
Pigeolet, Etienne;
Ogungbenro, Kayode;
Aarons, Leon

Publication type:

Article

Empirical and Semi-Mechanistic Modelling of Double-Peaked Pharmacokinetic Profile Phenomenon Due to Gastric Emptying.

Published in:

AAPS Journal, 2015, v. 17, n. 1, p. 227, doi. 10.1208/s12248-014-9693-5

By:

Ogungbenro, Kayode;
Pertinez, Henry;
Aarons, Leon

Publication type:

Article

Model-Based Evaluation of the Impact of Formulation and Food Intake on the Complex Oral Absorption of Mavoglurant in Healthy Subjects.

Published in:

Pharmaceutical Research, 2015, v. 32, n. 5, p. 1764, doi. 10.1007/s11095-014-1574-1

By:

Wendling, Thierry;
Ogungbenro, Kayode;
Pigeolet, Etienne;
Dumitras, Swati;
Woessner, Ralph;
Aarons, Leon

Publication type:

Article

A Physiologically Based Pharmacokinetic Model for Clobazam and Stiripentol in Adults and Children.

Published in:

Pharmaceutical Research, 2015, v. 32, n. 1, p. 144, doi. 10.1007/s11095-014-1451-y

By:

Ogungbenro, Kayode;
Aarons, Leon

Publication type:

Article

A Semi-mechanistic Gastric Emptying Model for the Population Pharmacokinetic Analysis of Orally Administered Acetaminophen in Critically Ill Patients.

Published in:

Pharmaceutical Research, 2011, v. 28, n. 2, p. 394, doi. 10.1007/s11095-010-0290-8

By:

Ogungbenro, Kayode;
Vasist, Lakshmi;
Maclaren, Robert;
Dukes, George;
Young, Malcolm;
Aarons, Leon

Publication type:

Article

Recommended approaches for integration of population pharmacokinetic modelling with precision dosing in clinical practice.

Published in:

British Journal of Clinical Pharmacology, 2025, v. 91, n. 4, p. 1064, doi. 10.1111/bcp.16335

By:

Berezowska, Monika;
Hayden, Isaac S.;
Brandon, Andrew M.;
Zats, Arsenii;
Patel, Mehzabin;
Barnett, Shelby;
Ogungbenro, Kayode;
Veal, Gareth J.;
Taylor, Alaric;
Suthar, Jugal

Publication type:

Article