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Perinatal Exposure of Patas Monkeys to Antiretroviral Nucleoside Reverse-Transcriptase Inhibitors Induces Genotoxicity Persistent for up to 3 Years of Age.
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- Journal of Infectious Diseases, 2013, v. 208, n. 2, p. 244, doi. 10.1093/infdis/jit146
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- Article
Incorporation of Zidovudine into Cord Blood DNA of Infants and Peripheral Blood DNA of Their HIV-1-Positive Mothers.
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- Annals of the New York Academy of Sciences, 2000, v. 918, n. 1, p. 262, doi. 10.1111/j.1749-6632.2000.tb05495.x
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- Article
Localization of DNA adducts induced by N-acetoxy-N-2-acetylaminofluorene in chinese hamster ovary cells using electron microscopy and colloidal gold.
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- Genes, Chromosomes & Cancer, 1990, v. 2, n. 2, p. 130, doi. 10.1002/gcc.2870020209
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- Article
Transplacental Carcinogenesis Induced by Antiretrovirals, Twelve Years Later.
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- Environmental & Molecular Mutagenesis, 2019, v. 60, n. 5, p. 443, doi. 10.1002/em.22289
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Introduction: Special Issue on Transplacental/Transgenerational Mutagenesis and Carcinogenesis.
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- Environmental & Molecular Mutagenesis, 2019, v. 60, n. 5, p. 392, doi. 10.1002/em.22292
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- Article
Role of nucleotide excision repair and p53 in zidovudine (AZT)-induced centrosomal deregulation.
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- Environmental & Molecular Mutagenesis, 2014, v. 55, n. 9, p. 719, doi. 10.1002/em.21889
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- Article
Selective protection of zidovudine-induced DNA-damage by the antioxidants WR-1065 and tempol.
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- Environmental & Molecular Mutagenesis, 2014, v. 55, n. 7, p. 566, doi. 10.1002/em.21872
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- Article
Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): Tumorigenicity in mice and...
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- JNCI: Journal of the National Cancer Institute, 1997, v. 89, n. 21, p. 1602, doi. 10.1093/jnci/89.21.1602
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Oxidative DNA damage in fetal tissues after transplacental exposure to 3′-azido-3′-deoxythymidine (AZT).
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- Carcinogenesis, 2000, v. 21, n. 5, p. 1059, doi. 10.1093/carcin/21.5.1059
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- Article
Impact of EMS Outreach: Successful Developments in Latin America.
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- Environmental & Molecular Mutagenesis, 2010, v. 51, n. 8/9, p. 763, doi. 10.1002/em.20563
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Assessment of multiple types of DNA damage in human placentas from smoking and nonsmoking women in the Czech Republic.
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- Environmental & Molecular Mutagenesis, 2011, v. 52, n. 1, p. 58, doi. 10.1002/em.20581
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- Article
Centrosome Structure and Function Under Normal and Pathological Conditions.
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- Environmental & Molecular Mutagenesis, 2009, v. 50, n. 8, p. 591, doi. 10.1002/em.20535
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- Article
Centrosome Amplification Induced by the Antiretroviral Nucleoside Reverse Transcriptase Inhibitors Lamivudine, Stavudine, and Didanosine.
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- Environmental & Molecular Mutagenesis, 2009, v. 50, n. 8, p. 718, doi. 10.1002/em.20509
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- Article
WR1065 Mitigates AZT-ddI-Induced Mutagenesis and Inhibits Viral Replication.
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- Environmental & Molecular Mutagenesis, 2009, v. 50, n. 6, p. 460, doi. 10.1002/em.20482
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Morphological and molecular course of mitochondrial pathology in cultured human cells exposed long‐term to ZidovudineThis article is a US Government work and, as such, is in the public domain in the United States of America.Invited article on the genotoxicity of perinatal NRTI therapy
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- Environmental & Molecular Mutagenesis, 2007, v. 48, n. 3/4, p. 179, doi. 10.1002/em.20245
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Plasma and cellular markers of 3′‐azido‐3′‐dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIsInvited article on the genotoxicity of perinatal NRTI therapy.Contributing investigators at clinical sites for the protocol entitled “A study of the potential mutagenicity of ZDV/nucleoside analogues in perinatal HIV prophylaxis” were Alan Bateman (Harlem Hospital Center, New York, NY), Eleanor Jimenez and Jorge Gandia (Centro Medico, San Juan, Puerto Rico), Renee Samelson (Albany Medical Center, Albany, NY), Sohail Rana (Howard University Hospital, Washington, DC), Andrea Kovacs and Alice Stek (University of Southern California Medical Center, Los Angeles, CA), and Mobeen H. Rathore and Isaac Delke (University of Florida Health Science Center, Jacksonville, FL).
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- Environmental & Molecular Mutagenesis, 2007, v. 48, n. 3/4, p. 307
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Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother–child pairs to AZT or AZT‐3TCInvited article on the genotoxicity of perinatal NRTI therapy.
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- Environmental & Molecular Mutagenesis, 2007, v. 48, n. 3/4, p. 330
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Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD‐1 mice to single agents or drug combinationsThe contents of this communication are the sole responsibility of the authors and do not necessarily represent official views of the NCI or the NIH.Invited article on the genotoxicity of perinatal NRTI therapy.
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- Environmental & Molecular Mutagenesis, 2007, v. 48, n. 3/4, p. 224, doi. 10.1002/em.20264
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Mechanisms of genotoxicity of nucleoside reverse transcriptase inhibitorsInvited article on the genotoxicity of perinatal NRTI therapy.This article is a US Government work and, as such, is in the public domain in the United States of America.
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- Environmental & Molecular Mutagenesis, 2007, v. 48, n. 3/4, p. 215, doi. 10.1002/em.20195
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Benzo[a]pyrene (BP) DNA adduct formation in DNA repair–deficient p53 haploinsufficient [Xpa(−/−)p53(+/−)] and wild-type mice fed BP and BP plus chlorophyllin for 28 days.
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- Carcinogenesis, 2012, v. 33, n. 11, p. 2236, doi. 10.1093/carcin/bgs247
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Harnessing the Power of Collaboration and Training Within Clinical Data Science to Generate Real‐World Evidence in the Era of Precision Oncology.
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- Clinical Pharmacology & Therapeutics, 2019, v. 106, n. 1, p. 60, doi. 10.1002/cpt.1459
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Anti-centrosome antibodies in breast cancer are the expression of autoimmunity.
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- Immunologic Research, 2014, v. 60, n. 2/3, p. 339, doi. 10.1007/s12026-014-8582-4
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Skin tumorigenesis and Ki- ras and Ha- ras mutations in tumors from adult mice exposed in utero to 3′-azido-2′,3′-dideoxythymidine.
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- Molecular Carcinogenesis, 1998, v. 23, n. 1, p. 45, doi. 10.1002/(SICI)1098-2744(199809)23:1<45::AID-MC6>3.0.CO;2-G
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- Article
Preferential incorporation of 3′-azido-2′,3′-dideoxythymidine into telomeric DNA and Z-DNA-containing regions of chinese hamster ovary cells.
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- Molecular Carcinogenesis, 1993, v. 8, n. 2, p. 81, doi. 10.1002/mc.2940080204
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- Article
Chromosome site-specific immunohistochemical detection of DNA adducts in N-acetoxy-2-acetylaminofluorene-exposed chinese hamster ovary cells.
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- Molecular Carcinogenesis, 1990, v. 3, n. 1, p. 37, doi. 10.1002/mc.2940030109
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Carcinogenicity. Relationships between DNA Incorporation, Mutant Frequency, and Loss of Heterozygosity at the TK Locus in Human Lymphoblastoid Cells Exposed to 3′-Azido-3′-deoxythymidine.
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- Toxicological Sciences, 2000, v. 54, n. 2, p. 322, doi. 10.1093/toxsci/54.2.322
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Cisplatin–DNA damage in p21WAF1/Cip1 deficient mouse keratinocytes exposed to cisplatin.
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- Mutagenesis, 2007, v. 22, n. 1, p. 49
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Zidovudine induces S-phase arrest and cell cycle gene expression changes in human cells.
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- Mutagenesis, 2005, v. 20, n. 2, p. 139, doi. 10.1093/mutage/gei019
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Autoantibodies in breast cancer sera are not epiphenomena and may participate in carcinogenesis.
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- BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1385-8
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- Article
Long-term AZT Exposure Alters the Metabolic Capacity of Cultured Human Lymphoblastoid Cells.
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- Toxicological Sciences, 2010, v. 115, n. 1, p. 109, doi. 10.1093/toxsci/kfq023
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- Article