Works by Octave, Jean-Noël

Results: 40

Alzheimer's Disease, a Lipid Story: Involvement of Peroxisome Proliferator-Activated Receptor α.

Published in:

Cells (2073-4409), 2020, v. 9, n. 5, p. 1215, doi. 10.3390/cells9051215

By:

Sáez-Orellana, Francisco;
Octave, Jean-Noël;
Pierrot, Nathalie

Publication type:

Article

Conditional deletion of KCC2 impairs synaptic plasticity and both spatial and nonspatial memory.

Published in:

Frontiers in Molecular Neuroscience, 2023, p. 1, doi. 10.3389/fnmol.2023.1081657

By:

Kreis, Anna;
Issa, Farah;
Yerna, Xavier;
Jabbour, Caren;
Schakman, Olivier;
de Clippele, Marie;
Tajeddine, Nicolas;
Pierrot, Nathalie;
Octave, Jean-Noël;
Gualdani, Roberta;
Gailly, Philippe

Publication type:

Article

Gamma-Secretase Inhibitor Activity of a Pterocarpus erinaceus Extract.

Published in:

Neurodegenerative Diseases, 2014, v. 14, n. 1, p. 39, doi. 10.1159/000355557

By:

Hage, Salim;
Marinangeli, Claudia;
Stanga, Serena;
Octave, Jean-Noël;
Quetin-Leclercq, Joëlle;
Kienlen-Campard, Pascal

Publication type:

Article

Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology.

Published in:

Frontiers in Physiology, 2017, p. 1, doi. 10.3389/fphys.2017.00796

By:

Contino, Sabrina;
Porporato, Paolo E.;
Bird, Matthew;
Marinangeli, Claudia;
Opsomer, Rémi;
Sonveaux, Pierre;
Bontemps, Françoise;
Dewachter, Ilse;
Octave, Jean-Noël;
Bertrand, Luc;
Stanga, Serena;
Kienlen-Campard, Pascal

Publication type:

Article

Expression of Human Amyloid Precursor Protein in Rat Cortical Neurons Inhibits Calcium Oscillations.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 15, p. 4708, doi. 10.1523/JNEUROSCI.4917-08.2009

By:

Santos, Susana Ferrao;
Pierrot, Nathalie;
Morel, Nicole;
Gailly, Philippe;
Sindic, Christian;
Octave, Jean-Noël

Publication type:

Article

Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease.

Published in:

2016

By:

Couturier, Julien;
Stancu, Ilie-Cosmin;
Schakman, Olivier;
Pierrot, Nathalie;
Huaux, François;
Kienlen-Campard, Pascal;
Dewachter, Ilse;
Octave, Jean-Noël

Publication type:

journal article

Amyloid precursor protein controls cholesterol turnover needed for neuronal activity.

Published in:

EMBO Molecular Medicine, 2013, v. 5, n. 4, p. 608, doi. 10.1002/emmm.201202215

By:

Pierrot, Nathalie;
Tyteca, Donatienne;
D'auria, Ludovic;
Dewachter, Ilse;
Gailly, Philippe;
Hendrickx, Aurélie;
Tasiaux, Bernadette;
Haylani, Laetitia El;
Muls, Nathalie;
N'Kuli, Francisca;
Laquerrière, Annie;
Demoulin, Jean‐Baptiste;
Campion, Dominique;
Brion, Jean‐Pierre;
Courtoy, Pierre J.;
Kienlen‐Campard, Pascal;
Octave, Jean‐Noël

Publication type:

Article

What is the role of amyloid precursor protein dimerization?

Published in:

Cell Adhesion & Migration, 2010, v. 4, n. 2, p. 268, doi. 10.4161/cam.4.2.11476

By:

Khalifa, Naouel Ben;
Hees, Joanne Van;
Tasiaux, Bernadette;
Huysseune, Sandra;
Smith, Steven O.;
Constantinescu, Stefan N.;
Octave, Jean-Noël;
Kienlen-Campard, Pascal

Publication type:

Article

Lack of Rapid Desensitization of Ca<sup>2+</sup> Responses in Transfected CHO Cells Expressing the Rat Neurotensin Receptor Despite Agonist-Induced Internalization.

Published in:

Journal of Neurochemistry, 1995, v. 64, n. 6, p. 2518, doi. 10.1046/j.1471-4159.1995.64062518.x

By:

Hermans, Emmanuel;
Gailly, Philippe;
Gillis, Jean Marie;
Octave, Jean-Noël;
Maloteaux, Jean-Marie

Publication type:

Article

Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo.

Published in:

Acta Neuropathologica, 2019, v. 137, n. 4, p. 599, doi. 10.1007/s00401-018-01957-y

By:

Cremers, Niels;
Vanrusselt, Hannah;
Kessels, Sofie;
Lodder, Chritica;
Brône, Bert;
Terwel, Dick;
Stancu, Ilie-Cosmin;
Dewachter, Ilse;
Couturier, Julien;
Vanoosthuyse, Alexandre;
Octave, Jean-Noël;
Huaux, François

Publication type:

Article

Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.

Published in:

Acta Neuropathologica, 2017, v. 133, n. 5, p. 731, doi. 10.1007/s00401-016-1663-9

By:

Wang, Peng;
Joberty, Gerard;
Buist, Arjan;
Vanoosthuyse, Alexandre;
Stancu, Ilie-Cosmin;
Vasconcelos, Bruno;
Pierrot, Nathalie;
Faelth-Savitski, Maria;
Kienlen-Campard, Pascal;
Octave, Jean-Noël;
Bantscheff, Marcus;
Drewes, Gerard;
Moechars, Diederik;
Dewachter, Ilse

Publication type:

Article

Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo.

Published in:

Acta Neuropathologica, 2016, v. 131, n. 4, p. 549, doi. 10.1007/s00401-015-1525-x

By:

Vasconcelos, Bruno;
Stancu, Ilie-Cosmin;
Buist, Arjan;
Bird, Matthew;
Wang, Peng;
Vanoosthuyse, Alexandre;
Kolen, Kristof;
Verheyen, An;
Kienlen-Campard, Pascal;
Octave, Jean-Noël;
Baatsen, Peter;
Moechars, Diederik;
Dewachter, Ilse

Publication type:

Article

CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01204-8

By:

Lodder, Chritica;
Scheyltjens, Isabelle;
Stancu, Ilie Cosmin;
Botella Lucena, Pablo;
Gutiérrez de Ravé, Manuel;
Vanherle, Sarah;
Vanmierlo, Tim;
Cremers, Niels;
Vanrusselt, Hannah;
Brône, Bert;
Hanseeuw, Bernard;
Octave, Jean-Noël;
Bottelbergs, Astrid;
Movahedi, Kiavash;
Dewachter, Ilse

Publication type:

Article

Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing.

Published in:

FEBS Open Bio, 2015, v. 5, p. 763, doi. 10.1016/j.fob.2015.09.002

By:

Decock, Marie;
El Haylani, Laetitia;
Stanga, Serena;
Dewachter, Ilse;
Octave, Jean-Noël;
Smith, Steven O.;
Constantinescu, Stefan N.;
Kienlen-Campard, Pascal

Publication type:

Article

Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells.

Published in:

Frontiers in Aging Neuroscience, 2016, p. 1, doi. 10.3389/fnagi.2016.00107

By:

Decock, Marie;
Stanga, Serena;
Octave, Jean-Noël;
Dewachter, Ilse;
Smith, Steven O.;
Constantinescu, Stefan N.;
Kienlen-Campard, Pascal;
Da Cruz E. Silva, Odete A. B.;
Kandimalla, Ramesh

Publication type:

Article

Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing.

Published in:

Frontiers in Cellular Neuroscience, 2018, p. N.PAG, doi. 10.3389/fncel.2018.00435

By:

Evrard, Caroline;
Kienlen-Campard, Pascal;
Coevoet, Mathilde;
Opsomer, Rémi;
Tasiaux, Bernadette;
Melnyk, Patricia;
Octave, Jean-Noël;
Buée, Luc;
Sergeant, Nicolas;
Vingtdeux, Valérie

Publication type:

Article

Cholestérol, activité neuronale et maladie d'Alzheimer.

Published in:

Médecine Sciences, 2014, v. 30, n. 3, p. 244, doi. 10.1051/medsci/20143003008

By:

Pierrot, Nathalie;
Octave, Jean-Noël

Publication type:

Article

APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation.

Published in:

FASEB Journal, 2016, v. 30, n. 5, p. 1696, doi. 10.1096/fj.15-278739

By:

Stanga, Serena;
Zanou, Nadège;
Audouard, Emilie;
Tasiaux, Bernadette;
Contino, Sabrina;
Vandermeulen, Gaëlle;
René, Frédérique;
Loeffler, Jean-Philippe;
Clotman, Frédéric;
Gailly, Philippe;
Dewachter, Ilse;
Octave, Jean-Noël;
Kienlen-Campard, Pascal

Publication type:

Article

Tauopathy contributes to synaptic and cognitive deficits in a murine model for Alzheimer's disease.

Published in:

FASEB Journal, 2014, v. 28, n. 6, p. 2620, doi. 10.1096/fj.13-246702

By:

Stancu, Ilie-Cosmin;
Ris, Laurence;
Vasconcelos, Bruno;
Marinangeli, Claudia;
Goeminne, Léonie;
Laporte, Vincent;
Haylani, Laetitia E.;
Couturier, Julien;
Schakman, Olivier;
Gailly, Philippe;
Pierrot, Nathalie;
Kienlen-Campard, Pascal;
Octave, Jean-Noël;
Dewachter, Ilse

Publication type:

Article

Structural features of the KPI domain control APP dimerization, trafficking, and processing.

Published in:

FASEB Journal, 2012, v. 26, n. 2, p. 855, doi. 10.1096/fj.11-190207

By:

Khalifa, Naouel Ben;
Tyteca, Donatienne;
Marinangeli, Claudia;
Depuydt, Mathieu;
Collet, Jean-François;
Courtoy, Pierre J.;
Renauld, Jean-Christophe;
Constantinescu, Stefan;
Octave, Jean-Noël;
Kienlen-Campard, Pascal

Publication type:

Article

Epigenetic control of aquaporin 1 expression by the amyloid precursor protein.

Published in:

FASEB Journal, 2009, v. 23, n. 12, p. 4158, doi. 10.1096/fj.09-140012

By:

Huysseune, Sandra;
Kienlen-Campard, Pascal;
Hébert, Sébastien;
Tasiaux, Bernadette;
Leroy, Karelle;
Devuyst, Olivier;
Brion, Jean-Pierre;
De Strooper, Bart;
Octave, Jean-Noël

Publication type:

Article

From synaptic spines to nuclear signaling: nuclear and synaptic actions of the amyloid precursor protein.

Published in:

Journal of Neurochemistry, 2013, v. 126, n. 2, p. 183, doi. 10.1111/jnc.12239

By:

Octave, Jean‐Noël;
Pierrot, Nathalie;
Ferao Santos, Susana;
Nalivaeva, Natalia N.;
Turner, Anthony J.

Publication type:

Article

Specific regulation of rat glial cell line-derived neurotrophic factor gene expression by riluzole in C6 glioma cells.

Published in:

Journal of Neurochemistry, 2006, v. 97, n. 1, p. 128, doi. 10.1111/j.1471-4159.2006.03711.x

By:

Caumont, Anne-Sophie;
Octave, Jean-Noël;
Hermans, Emmanuel

Publication type:

Article

Epigenetic Regulations of Immediate Early Genes Expression Involved in Memory Formation by the Amyloid Precursor Protein of Alzheimer Disease.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099467

By:

Hendrickx, Aurélie;
Pierrot, Nathalie;
Tasiaux, Bernadette;
Schakman, Olivier;
Kienlen-Campard, Pascal;
De Smet, Charles;
Octave, Jean-Noël

Publication type:

Article

Epigenetic Induction of EGR-1 Expression by the Amyloid Precursor Protein during Exposure to Novelty.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074305

By:

Hendrickx, Aurélie;
Pierrot, Nathalie;
Tasiaux, Bernadette;
Schakman, Olivier;
Brion, Jean-Pierre;
Kienlen-Campard, Pascal;
De Smet, Charles;
Octave, Jean-Noël

Publication type:

Article

Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-97144-3

By:

Kreis, Anna;
Desloovere, Jana;
Suelves, Nuria;
Pierrot, Nathalie;
Yerna, Xavier;
Issa, Farah;
Schakman, Olivier;
Gualdani, Roberta;
de Clippele, Marie;
Tajeddine, Nicolas;
Kienlen-Campard, Pascal;
Raedt, Robrecht;
Octave, Jean-Noël;
Gailly, Philippe

Publication type:

Article

Editorial: Risk Factors and Outcome Predicating Biomarker of Neurodegenerative Diseases.

Published in:

Frontiers in Neurology, 2019, p. N.PAG, doi. 10.3389/fneur.2019.00045

By:

Hu, Chaur-Jong;
Octave, Jean-Noël

Publication type:

Article

A Role for GDNF and Soluble APP as Biomarkers of Amyotrophic Lateral Sclerosis Pathophysiology.

Published in:

Frontiers in Neurology, 2018, p. 1, doi. 10.3389/fneur.2018.00384

By:

Stanga, Serena;
Brambilla, Liliana;
Tasiaux, Bernadette;
Dang, Anh H.;
Ivanoiu, Adrian;
Octave, Jean-Noël;
Rossi, Daniela;
van Pesch, Vincent;
Kienlen-Campard, Pascal

Publication type:

Article

IDENTIFICATION OF NOVEL TARGETS FOR INHIBITING PRION-LIKE SEEDING AND PROPAGATION OF TAU PATHOLOGY IN VITRO AND IN VIVO.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1270, doi. 10.1016/j.jalz.2017.06.1901

By:

Dewachter, Ilse;
Stancu, Ilie-Cosmin;
Vanoosthuyse, Alexandre;
Buist, Arjan;
Vasconcelos, Bruno;
Wang, Peng;
Kienlen-Campard, Pascal;
Octave, Jean-Noël;
Moechars, Diederik

Publication type:

Article

MOLECULAR MECHANISMS OF ABETA-INDUCED TAU-PATHOLOGY: ANALYSIS OF CROSS-SEEDING OF ABETA AND TAU AND ITS ROLE IN PRION-LIKE PROPAGATION OF TAU-PATHOLOGY IN VITRO AND IN VIVO.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P385, doi. 10.1016/j.jalz.2016.06.722

By:

Vasconcelos, Bruno;
Stancu, Ilie-Cosmin;
Buist, Arjan;
Bird, Matthew;
Wang, Peng;
Vanoosthuyse, Alexandre;
Van Kolen, Kristof;
Verheyen, An;
Kienlen-Campard, Pascal;
Octave, Jean-Noël;
Baatsen, Peter;
Moechars, Diederik;
Dewachter, Ilse

Publication type:

Article

Structural features of the extracellular and juxta/transmembrane domains controlling APP dimerization, trafficking and processing

Published in:

2012

By:

Kienlen-Campard, Pascal;
Tyteca, Donatienne;
Ben Khalifa, Naouel;
Marinangeli, Claudia;
Decock, Marie;
Collet, Jean-François;
Courtoy, Pierre J.;
Renauld, Jean-Christophe;
Constantinescu, Stefan;
Octave, Jean-Noël

Publication type:

Abstract

Amyloid precursor protein regulates neuronal cholesterol turnover needed for synaptic activity

Published in:

2012

By:

Pierrot, Nathalie;
Tyteca, Donatienne;
d'Auria, Ludovic;
Dewachter, Ilse;
Gailly, Philippe;
Ris, Laurence;
El Haylani, Laetitia;
Tasiaux, Bernadette;
Muls, Nathalie;
N'Kuli, Francisca;
Courtoy, Pierre J.;
Kienlen-Campard, Pascal;
Octave, Jean-Noël

Publication type:

Abstract

Tau deletion rescues neuronal death in APP/PS1 mice

Published in:

2012

By:

Leroy, Karelle;
Ando, Kunie;
Laporte, Vincent;
Dedecker, Robert;
Suain, Valérie;
Authelet, Michèle;
Héraud, Céline;
Pierrot, Nathalie;
Yilmaz, Zehra;
Octave, Jean-Noël;
Brion, Jean-Pierre

Publication type:

Abstract

The Kunitz protease inhibitor domain controls homodimerization of the amyloid precursor protein

Published in:

2010

By:

Ben Khalifa, Naouel;
Renauld, Jean-Christophe;
Courtoy, Pierre J.;
Tyteca, Donatienne;
Collet, Jean-François;
Depuydt, Matthieu;
Octave, Jean-Noël;
Constantinescu, Stefan N.;
Kienlen-Campard, Pascal

Publication type:

Abstract

Epigenetic control of Aquaporin 1 expression by the amyloid precursor protein

Published in:

2009

By:

Huysseune, Sandra;
Kienlen-Campard, Pascal;
Hébert, Sébastien;
Brion, Jean-Pierre;
de Strooper, Bart;
Octave, Jean-Noël

Publication type:

Abstract

Control of genes transcription involved in neuronal lipids metabolism by the amyloid precursor protein APP

Published in:

2009

By:

Pierrot, Nathalie;
D'auria, Ludovic;
Tyteca, Donatienne;
Van Biervliet, Laurie;
Muls, Nathalie;
Courtoy, Pierre;
Octave, Jean-Noël

Publication type:

Abstract

Analysis of the dimerization and metabolism of different APP isoforms

Published in:

2009

By:

Ben Khalifa, Naouel;
Constantinescu, Stefan N.;
Tasiaux, Bernadette;
Van Hees, Joanne;
Courtoy, Pierre J.;
Vandersmissen, Patrick;
Renauld, Jean-Christophe;
Smith, Steven O.;
Octave, Jean-Noël;
Kienlen-Campard, Pascal

Publication type:

Abstract

P1-425: Dimerization and orientation of the transmembrane domain control APP amyloidogenic processing

Published in:

2008

By:

Kienlen-Campard, Pascal;
Constantinescu, Stefan N.;
Tasiaux, Bernadette;
Van Hees, Joanne;
Khalifa, Naouel Ben;
Huysseune, Sandra;
Sato, Takeshi;
Courtoy, Pierre J.;
Smith, Steven O.;
Octave, Jean-Noël

Publication type:

Abstract

O2-03-02: Role of the transmembrane GxxxG motifs in the processing of human APP

Published in:

2006

By:

Kienlen-Campard, Pascal;
Constantinescu, Stefan N.;
Tasiaux, Bernadette;
Smith, Steven O.;
Octave, Jean-Noël

Publication type:

Abstract

O2-03-02: Role of the transmembrane GxxxG motifs in the processing of human APP

Published in:

2006

By:

Kienlen-Campard, Pascal;
Constantinescu, Stefan N.;
Tasiaux, Bernadette;
Smith, Steven O.;
Octave, Jean-Noël

Publication type:

Abstract