Works by Obrecht, Denise

Results: 25

Impact of molecular classification on prognosis in children and adolescents with spinal ependymoma: Results from the HIT-MED database.

Published in:

Neuro-Oncology Advances, 2024, v. 6, n. 1, p. 1, doi. 10.1093/noajnl/vdae179

By:

Engertsberger, Lara;
Benesch, Martin;
Mynarek, Martin;
Tonn, Svenja;
Obrecht-Sturm, Denise;
Perwein, Thomas;
Stickan-Verfürth, Martina;
Funk, Angela;
Timmermann, Beate;
Bockmayr, Michael;
Eckhardt, Alicia;
Claviez, Alexander;
Kortmann, Rolf-Dieter;
Riemenschneider, Markus J;
Pietsch, Torsten;
Bison, Brigitte;
Warmuth-Metz, Monika;
Pajtler, Kristian W;
Rutkowski, Stefan;
Schüller, Ulrich

Publication type:

Article

A multi-institutional retrospective pooled outcome analysis of molecularly annotated pediatric supratentorial ZFTA-fused ependymoma.

Published in:

Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad057

By:

Ng, Chia Huan;
Obrecht, Denise;
Wells, Olivia;
Zapotocky, Michal;
Sumerauer, David;
Coltin, Hallie;
Khuong-Quang, Dong-Anh;
Eisenstat, David D;
Kinross, Kathryn M;
White, Christine L;
Algar, Elizabeth M;
Luck, Amanda;
Witt, Hendrik;
Schüller, Ulrich;
Mynarek, Martin;
Pietsch, Torsten;
Gerber, Nicolas U;
Benesch, Martin;
Warmuth-Metz, Monika;
Kortmann, Rolf

Publication type:

Article

Radiotherapy for Recurrent Medulloblastoma in Children and Adolescents: Survival after Re-Irradiation and First-Time Irradiation.

Published in:

Cancers, 2024, v. 16, n. 11, p. 1955, doi. 10.3390/cancers16111955

By:

Adolph, Jonas E.;
Fleischhack, Gudrun;
Tschirner, Sebastian;
Rink, Lydia;
Dittes, Christine;
Mikasch, Ruth;
Dammann, Philipp;
Mynarek, Martin;
Obrecht-Sturm, Denise;
Rutkowski, Stefan;
Bison, Brigitte;
Warmuth-Metz, Monika;
Pietsch, Torsten;
Pfister, Stefan M.;
Pajtler, Kristian W.;
Milde, Till;
Kortmann, Rolf-Dieter;
Dietzsch, Stefan;
Timmermann, Beate;
Tippelt, Stephan

Publication type:

Article

Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology.

Published in:

Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-023-02682-x

By:

Gödicke, Swenja;
Kresbach, Catena;
Ehlert, Max;
Obrecht, Denise;
Altendorf, Lea;
Hack, Karoline;
von Hoff, Katja;
Carén, Helena;
Melcher, Viktoria;
Kerl, Kornelius;
Englinger, Bernhard;
Filbin, Mariella;
Pajtler, Kristian W.;
Gojo, Johannes;
Pietsch, Torsten;
Rutkowski, Stefan;
Schüller, Ulrich

Publication type:

Article

Molecular characteristics and improved survival prediction in a cohort of 2023 ependymomas.

Published in:

Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-023-02674-x

By:

Pohl, Lara C.;
Leitheiser, Maximilian;
Obrecht, Denise;
Schweizer, Leonille;
Wefers, Annika K.;
Eckhardt, Alicia;
Raffeld, Mark;
Sturm, Dominik;
Pajtler, Kristian W.;
Rutkowski, Stefan;
Fukuoka, Kohei;
Ichimura, Koichi;
Bockmayr, Michael;
Schüller, Ulrich

Publication type:

Article

Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation.

Published in:

Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-023-02668-9

By:

Neyazi, Sina;
Yamazawa, Erika;
Hack, Karoline;
Tanaka, Shota;
Nagae, Genta;
Kresbach, Catena;
Umeda, Takayoshi;
Eckhardt, Alicia;
Tatsuno, Kenji;
Pohl, Lara;
Hana, Taijun;
Bockmayr, Michael;
Kim, Phyo;
Dorostkar, Mario M.;
Takami, Toshihiro;
Obrecht, Denise;
Takai, Keisuke;
Suwala, Abigail K.;
Komori, Takashi;
Godbole, Shweta

Publication type:

Article

Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts.

Published in:

Acta Neuropathologica, 2023, v. 145, n. 1, p. 97, doi. 10.1007/s00401-022-02522-4

By:

Mynarek, Martin;
Obrecht, Denise;
Sill, Martin;
Sturm, Dominik;
Kloth-Stachnau, Katja;
Selt, Florian;
Ecker, Jonas;
von Hoff, Katja;
Juhnke, Björn-Ole;
Goschzik, Tobias;
Pietsch, Torsten;
Bockmayr, Michael;
Kool, Marcel;
von Deimling, Andreas;
Witt, Olaf;
Schüller, Ulrich;
Benesch, Martin;
Gerber, Nicolas U.;
Sahm, Felix;
Jones, David T. W.

Publication type:

Article

Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 6, p. 1143, doi. 10.1007/s00401-022-02505-5

By:

Goschzik, Tobias;
Mynarek, Martin;
Doerner, Evelyn;
Schenk, Alina;
Spier, Isabel;
Warmuth-Metz, Monika;
Bison, Brigitte;
Obrecht, Denise;
Struve, Nina;
Kortmann, Rolf-Dieter;
Schmid, Matthias;
Aretz, Stefan;
Rutkowski, Stefan;
Pietsch, Torsten

Publication type:

Article

Molecular characterization of histopathological ependymoma variants.

Published in:

Acta Neuropathologica, 2020, v. 139, n. 2, p. 305, doi. 10.1007/s00401-019-02090-0

By:

Neumann, Julia E.;
Spohn, Michael;
Obrecht, Denise;
Mynarek, Martin;
Thomas, Christian;
Hasselblatt, Martin;
Dorostkar, Mario M.;
Wefers, Annika K.;
Frank, Stephan;
Monoranu, Camelia-Maria;
Koch, Arend;
Witt, Hendrik;
Kool, Marcel;
Pajtler, Kristian W.;
Rutkowski, Stefan;
Glatzel, Markus;
Schüller, Ulrich

Publication type:

Article

Distinct relapse pattern across molecular ependymoma types.

Published in:

Neuro-Oncology, 2025, v. 27, n. 1, p. 267, doi. 10.1093/neuonc/noae166

By:

Obrecht-Sturm, Denise;
Schoof, Melanie;
Eckhardt, Alicia;
Mynarek, Martin;
Gilbert, Mark R;
Aldape, Kenneth;
Armstrong, Terri S;
Ramaswamy, Vijay;
Bockmayr, Michael;
Hoff, Katja von;
Fleischhack, Gudrun;
Adolph, Jonas E;
Tippelt, Stephan;
Pfister, Stefan M;
Pajtler, Kristian;
Sturm, Dominik;
Drexler, Richard;
Ricklefs, Franz L;
Stepien, Natalia;
Gojo, Johannes

Publication type:

Article

Medulloblastoma in children with Fanconi anemia: Association with FA-D1/FA-N, SHH type and poor survival independent of treatment strategies.

Published in:

Neuro-Oncology, 2024, v. 26, n. 11, p. 2125, doi. 10.1093/neuonc/noae111

By:

Sönksen, Marthe;
Obrecht-Sturm, Denise;
Driever, Pablo Hernáiz;
Sauerbrey, Axel;
Graf, Norbert;
Kontny, Udo;
Reimann, Christian;
Langhein, Mina;
Kordes, Uwe R;
Schwarz, Rudolf;
Obser, Tobias;
Boschann, Felix;
Schüller, Ulrich;
Altendorf, Lea;
Goschzik, Tobias;
Pietsch, Torsten;
Mynarek, Martin;
Rutkowski, Stefan

Publication type:

Article

Risk factors for domain-specific neurocognitive outcome in pediatric survivors of a brain tumor in the posterior fossa—Results of the HIT 2000 trial.

Published in:

Neuro-Oncology, 2024, v. 26, n. 11, p. 2113, doi. 10.1093/neuonc/noae092

By:

Mynarek, Martin;
Rossius, Anne;
Guiard, Anika;
Ottensmeier, Holger;
Hoff, Katja von;
Obrecht-Sturm, Denise;
Bußenius, Lisa;
Friedrich, Carsten;
Bueren, Andre O von;
Gerber, Nicolas U;
Traunwieser, Thomas;
Kortmann, Rolf-Dieter;
Warmuth-Metz, Monika;
Bison, Brigitte;
Thomale, Ulrich-W;
Krauss, Juergen;
Pietsch, Torsten;
Clifford, Steven C;
Pfister, Stefan M;
Sturm, Dominik

Publication type:

Article

Treatment response as surrogate to predict risk for disease progression in pediatric medulloblastoma with persistent magnetic resonance imaging lesions after first-line treatment.

Published in:

Neuro-Oncology, 2024, v. 26, n. 9, p. 1712, doi. 10.1093/neuonc/noae071

By:

Obrecht-Sturm, Denise;
Schömig, Lena;
Mynarek, Martin;
Bison, Brigitte;
Schwarz, Rudolf;
Pietsch, Torsten;
Pfister, Stefan M;
Sill, Martin;
Sturm, Dominik;
Sahm, Felix;
Kortmann, Rolf-Dieter;
Gerber, Nicolas U;
Bueren, André O von;
Fleischhack, Gudrun;
Schüller, Ulrich;
Nussbaumer, Gunther;
Benesch, Martin;
Rutkowski, Stefan

Publication type:

Article

Integrated proteomics spotlight the proteasome as a therapeutic vulnerability in embryonal tumors with multilayered rosettes.

Published in:

Neuro-Oncology, 2024, v. 26, n. 5, p. 935, doi. 10.1093/neuonc/noad265

By:

Dottermusch, Matthias;
Biabani, Ali;
Lempertz, Tasja;
Schumann, Yannis;
Navolic, Jelena;
Godbole, Shweta;
Obrecht, Denise;
Frank, Stephan;
Dorostkar, Mario M;
Voß, Hannah;
Schlüter, Hartmut;
Rutkowski, Stefan;
Schüller, Ulrich;
Neumann, Julia E

Publication type:

Article

Clinical outcome of pediatric medulloblastoma patients with Li–Fraumeni syndrome.

Published in:

Neuro-Oncology, 2023, v. 25, n. 12, p. 2273, doi. 10.1093/neuonc/noad114

By:

Kolodziejczak, Anna S;
Guerrini-Rousseau, Lea;
Planchon, Julien Masliah;
Ecker, Jonas;
Selt, Florian;
Mynarek, Martin;
Obrecht, Denise;
Sill, Martin;
Autry, Robert J;
Stutheit-Zhao, Eric;
Hirsch, Steffen;
Amouyal, Elsa;
Dufour, Christelle;
Ayrault, Olivier;
Torrejon, Jacob;
Waszak, Sebastian M;
Ramaswamy, Vijay;
Pentikainen, Virve;
Demir, Haci Ahmet;
Clifford, Steven C

Publication type:

Article

Risk prediction in early childhood sonic hedgehog medulloblastoma treated with radiation-avoiding chemotherapy: Evidence for more than 2 subgroups.

Published in:

Neuro-Oncology, 2023, v. 25, n. 8, p. 1518, doi. 10.1093/neuonc/noad027

By:

Tonn, Svenja;
Korshunov, Andrey;
Obrecht, Denise;
Sill, Martin;
Spohn, Michael;
Hoff, Katja von;
Milde, Till;
Pietsch, Torsten;
Goschzik, Tobias;
Bison, Brigitte;
Juhnke, Björn-Ole;
Struve, Nina;
Sturm, Dominik;
Sahm, Felix;
Bockmayr, Michael;
Friedrich, Carsten;
Bueren, André O von;
Gerber, Nicolas U;
Benesch, Martin;
Jones, David T W

Publication type:

Article

Local and systemic therapy of recurrent ependymoma in children and adolescents: short- and long-term results of the E-HIT-REZ 2005 study.

Published in:

Neuro-Oncology, 2021, v. 23, n. 6, p. 1012, doi. 10.1093/neuonc/noaa276

By:

Adolph, Jonas E;
Fleischhack, Gudrun;
Mikasch, Ruth;
Zeller, Julia;
Warmuth-Metz, Monika;
Bison, Brigitte;
Mynarek, Martin;
Rutkowski, Stefan;
Schüller, Ulrich;
Hoff, Katja von;
Obrecht, Denise;
Pietsch, Torsten;
Pfister, Stefan M;
Pajtler, Kristian W;
Witt, Olaf;
Witt, Hendrik;
Kortmann, Rolf-Dieter;
Timmermann, Beate;
Krauß, Jürgen;
Frühwald, Michael C

Publication type:

Article

Pineal anlage tumor: clinical and diagnostic features, and rationales for treatment.

Published in:

Journal of Neuro-Oncology, 2024, v. 166, n. 2, p. 359, doi. 10.1007/s11060-023-04547-5

By:

Obrecht-Sturm, Denise;
Pfaff, Elke;
Mynarek, Martin;
Bison, Brigitte;
Rodehüser, Martina;
Becker, Martina;
Kietz, Silke;
Pfister, Stefan M.;
Jones, David T.;
Sturm, Dominik;
von Deimling, Andreas;
Sahm, Felix;
Kortmann, Rolf-Dieter;
Schwarz, Rudolf;
Pietsch, Torsten;
Fleischhack, Gudrun;
Rutkowski, Stefan

Publication type:

Article

Clinical and molecular characterization of isolated M1 disease in pediatric medulloblastoma: experience from the German HIT-MED studies.

Published in:

Journal of Neuro-Oncology, 2022, v. 157, n. 1, p. 37, doi. 10.1007/s11060-021-03913-5

By:

Obrecht, Denise;
Mynarek, Martin;
Hagel, Christian;
Kwiecien, Robert;
Spohn, Michael;
Bockmayr, Michael;
Bison, Brigitte;
Pfister, Stefan M.;
Jones, David T. W.;
Sturm, Dominik;
von Deimling, Andreas;
Sahm, Felix;
von Hoff, Katja;
Juhnke, B.-Ole;
Benesch, Martin;
Gerber, Nicolas U.;
Friedrich, Carsten;
von Bueren, André O.;
Kortmann, Rolf-Dieter;
Schwarz, Rudolf

Publication type:

Article

Recurrence patterns in pediatric intracranial ependymal neoplasm: a systematic imaging work-up.

Published in:

Neuroradiology, 2025, v. 67, n. 3, p. 767, doi. 10.1007/s00234-025-03553-w

By:

Stock, Annika;
Krumma, Judith;
Fleischhack, Gudrun;
Tippelt, Stephan;
Rink, Lydia;
Pietsch, Torsten;
Mynarek, Martin;
Obrecht-Sturm, Denise;
Rutkowski, Stefan;
Pfister, Stefan M.;
Sturm, Dominik;
Pajtler, Kristian W.;
Schüller, Ulrich;
Timmermann, Beate;
Kortmann, Rolf-Dieter;
Bison, Brigitte;
Pham, Mirko;
Warmuth-Metz, Monika

Publication type:

Article

Effect of cerebral circulatory arrest on cerebral near-infrared spectroscopy in pediatric patients.

Published in:

Pediatric Anesthesia, 2014, v. 24, n. 4, p. 393, doi. 10.1111/pan.12328

By:

Blohm, Martin E.;
Obrecht, Denise;
Hartwich, Jana;
Singer, Dominique;
Bosenberg, Adrian

Publication type:

Article

Effect of patent ductus arteriosus and patent foramen ovale on left ventricular stroke volume measurement by electrical velocimetry in comparison to transthoracic echocardiography in neonates.

Published in:

2017

By:

Blohm, Martin;
Hartwich, Jana;
Obrecht, Denise;
Kersten, Jan;
Singer, Dominique;
Blohm, Martin Ernst;
Kersten, Jan Felix

Publication type:

journal article

Defining the Spectrum, Treatment and Outcome of Patients With Genetically Confirmed Gorlin Syndrome From the HIT-MED Cohort.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.756025

By:

Kloth, Katja;
Obrecht, Denise;
Sturm, Dominik;
Pietsch, Torsten;
Warmuth-Metz, Monika;
Bison, Brigitte;
Mynarek, Martin;
Rutkowski, Stefan

Publication type:

Article

Impedance cardiography (electrical velocimetry) and transthoracic echocardiography for non-invasive cardiac output monitoring in pediatric intensive care patients: a prospective single-center observational study.

Published in:

Critical Care, 2014, v. 18, n. 6, p. 603, doi. 10.1186/s13054-014-0603-0

By:

Blohm, Martin Ernst;
Obrecht, Denise;
Hartwich, Jana;
Mueller, Goetz Christoph;
Kersten, Jan Felix;
Weil, Jochen;
Singer, Dominique

Publication type:

Article

Leptomeningeal Dissemination in Choroid Plexus Tumors: Magnetic Resonance Imaging Appearance and Risk Factors.

Published in:

Children, 2025, v. 12, n. 1, p. 82, doi. 10.3390/children12010082

By:

Nunes do Espirito Santo, Daniel;
Warmuth-Metz, Monika;
Monoranu, Camelia-Maria;
Hasselblatt, Martin;
Thomas, Christian;
Pietsch, Torsten;
Krauß, Jürgen;
Schweitzer, Tilmann;
Bison, Brigitte;
Eyrich, Matthias;
Kordes, Uwe;
Obrecht-Sturm, Denise;
Pham, Mirko;
Quenzer, Annika

Publication type:

Article