Works by OREKHOV, Alexander A.

Results: 245

Current use and development of monoclonal antibodies for the treatment of systemic lupus erythematosus: a review Open Access.

Published in:

Antibody Therapeutics, 2025, v. 8, n. 1, p. 47, doi. 10.1093/abt/tbae033

By:

Blagov, Alexander;
Orekhov, Nikolay;
Churov, Alexey;
Starodubtseva, Irina;
Beloyartsev, Dmitry;
Kovyanova, Tatiana;
Sukhorukov, Vasily;
Orekhov, Alexander

Publication type:

Article

Necroptosis in myocardial ischaemia-reperfusion injury: current update on mechanisms, therapeutic targets, and translational potential.

Published in:

Apoptosis, 2025, v. 30, n. 5, p. 1216, doi. 10.1007/s10495-025-02108-x

By:

Dabravolski, Siarhei A.;
Kalmykov, Vladislav A.;
Maksaeva, Anastasia O.;
Rozhkova, Ulyana V.;
Lapshina, Ksenia O.;
Orekhov, Alexander N.

Publication type:

Article

Impaired LPS tolerance in monocytes of coronary atherosclerosis patients is associated with the intermediate subset.

Published in:

Journal of Leukocyte Biology, 2025, v. 117, n. 5, p. 1, doi. 10.1093/jleuko/qiaf060

By:

Nikiforov, Nikita G;
Chegodaev, Yegor S;
Verkhova, Svetlana S;
Pudova, Elena A;
Popov, Mikhail A;
Tvorogova, Anna V;
Zhuravlev, Alexander D;
Maslennikov, Ruslan A;
Snezhkina, Anastasiya V;
Kudryavtseva, Anna V;
Yegorov, Yegor E;
Omelchenko, Andrey V;
Borodko, Daria D;
Zybin, Dmitry I;
Shumakov, Dmitry V;
Orekhov, Alexander N

Publication type:

Article

Rheumatoid Arthritis: What Inflammation Do We Face?

Published in:

Journal of Molecular Pathology, 2024, v. 5, n. 4, p. 454, doi. 10.3390/jmp5040030

By:

Poznyak, Anastasia V.;
Kirichenko, Tatyana Vladimirovna;
Beloyartsev, Dmitry Felixovich;
Churov, Alexey V.;
Kovyanova, Tatiana Ivanovna;
Starodubtseva, Irina Alexandrovna;
Sukhorukov, Vasily N.;
Antonov, Stanislav A.;
Orekhov, Alexander N.

Publication type:

Article

Role of Cathelicidins in Atherosclerosis and Associated Cardiovascular Diseases.

Published in:

Journal of Molecular Pathology, 2024, v. 5, n. 3, p. 319, doi. 10.3390/jmp5030023

By:

Dabravolski, Siarhei A.;
Orekhov, Nikolay A.;
Churov, Alexey V.;
Starodubtseva, Irina A.;
Beloyartsev, Dmitry F.;
Kovyanova, Tatiana I.;
Sukhorukov, Vasily N.;
Orekhov, Alexander N.

Publication type:

Article

Immune-Inflammatory Responses in Atherosclerosis: The Role of Myeloid Cells.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 11, p. 1798, doi. 10.3390/jcm8111798

By:

Chistiakov, Dimitry A.;
Kashirskikh, Dmitry A.;
Khotina, Victoriya A.;
Grechko, Andrey V.;
Orekhov, Alexander N.

Publication type:

Article

Effects of Metabolic Disorders in Immune Cells and Synoviocytes on the Development of Rheumatoid Arthritis.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 7, p. N.PAG, doi. 10.3390/metabo12070634

By:

Blagov, Alexander V.;
Grechko, Andrey V.;
Nikiforov, Nikita G.;
Zhuravlev, Alexander D.;
Sadykhov, Nikolay K.;
Orekhov, Alexander N.

Publication type:

Article

Regulatory T Cells in Atherosclerosis: Is Adoptive Cell Therapy Possible?

Published in:

Life (2075-1729), 2023, v. 13, n. 9, p. 1931, doi. 10.3390/life13091931

By:

Churov, Alexey V.;
Chegodaev, Yegor S.;
Khotina, Victoria A.;
Ofitserov, Vladimir P.;
Orekhov, Alexander N.

Publication type:

Article

The Role of Mitochondrial Mutations in Chronification of Inflammation: Hypothesis and Overview of Own Data.

Published in:

Life (2075-1729), 2022, v. 12, n. 8, p. 1153, doi. 10.3390/life12081153

By:

Orekhov, Alexander N.;
Nikiforov, Nikita G.;
Omelchenko, Andrey V.;
Sinyov, Vasily V.;
Sobenin, Igor A.;
Vinokurov, Andrey Y.;
Orekhova, Varvara A.

Publication type:

Article

Overview of OxLDL and Its Impact on Cardiovascular Health: Focus on Atherosclerosis.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.613780

By:

Poznyak, Anastasia V.;
Nikiforov, Nikita G.;
Markin, Alexander M.;
Kashirskikh, Dmitry A.;
Myasoedova, Veronika A.;
Gerasimova, Elena V.;
Orekhov, Alexander N.

Publication type:

Article

Cellular Mechanisms of Human Atherogenesis: Focus on Chronification of Inflammation and Mitochondrial Mutations.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00642

By:

Markin, Alexander M.;
Sobenin, Igor A.;
Grechko, Andrey V.;
Zhang, Dongwei;
Orekhov, Alexander N.

Publication type:

Article

Medicinal Plants as a Potential and Successful Treatment Option in the Context of Atherosclerosis.

Published in:

Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00403

By:

Kirichenko, Tatiana V.;
Sukhorukov, Vasily N.;
Markin, Alexander M.;
Nikiforov, Nikita G.;
Liu, Ping-Yen;
Sobenin, Igor A.;
Tarasov, Vadim V.;
Orekhov, Alexander N.;
Aliev, Gjumrakch

Publication type:

Article

Atherosclerosis originating from childhood: Specific features.

Published in:

Journal of Biomedical Research, 2024, v. 38, n. 3, p. 233, doi. 10.7555/JBR.37.20230198

By:

Poznyak, Anastasia V.;
Yakovlev, Alexey A.;
Popov, Mikhail A.;
Zhigmitova, Elena B.;
Sukhorukov, Vasily N.;
Orekhov, Alexander N.

Publication type:

Article

Response to: Comment on “Role of Mitochondrial Genome Mutations in Pathogenesis of Carotid Atherosclerosis”.

Published in:

Oxidative Medicine & Cellular Longevity, 2018, p. 1, doi. 10.1155/2018/7620234

By:

Sobenin, Igor A.;
Sazonova, Margarita A.;
Sinyov, Vasily V.;
Ryzhkova, Anastasia I.;
Galitsyna, Elena V.;
Khasanova, Zukhra B.;
Postnov, Anton Y.;
Yarygina, Elena I.;
Shkurat, Tatiana P.;
Orekhov, Alexander N.

Publication type:

Article

Cybrid Models of Pathological Cell Processes in Different Diseases.

Published in:

Oxidative Medicine & Cellular Longevity, 2018, p. 1, doi. 10.1155/2018/4647214

By:

Sazonova, Margarita A.;
Sinyov, Vasily V.;
Ryzhkova, Anastasia I.;
Galitsyna, Elena V.;
Melnichenko, Alexandra A.;
Postnov, Anton Y.;
Orekhov, Alexander N.;
Sobenin, Igor A.

Publication type:

Article

The Effects of Antihypertensive Agents on Atherosclerosis-Related Parameters of Human Aorta Intimal Cells.

Published in:

Cardiology, 1998, v. 89, n. 2, p. 111, doi. 10.1159/000006765

By:

Orekhov, Alexander N.;
Tertov, Vladimir V.;
Pivovarova, Elena M.

Publication type:

Article

T Helper Lymphocyte Subsets and Plasticity in Autoimmunity and Cancer: An Overview.

Published in:

BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/327470

By:

Ivanova, Ekaterina A.;
Orekhov, Alexander N.

Publication type:

Article

Human miR-221/222 in Physiological and Atherosclerotic Vascular Remodeling.

Published in:

BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/354517

By:

Chistiakov, Dmitry A.;
Sobenin, Igor A.;
Orekhov, Alexander N.;
Bobryshev, Yuri V.

Publication type:

Article

Mosaicism of Mitochondrial Genetic Variation in Atherosclerotic Lesions of the Human Aorta.

Published in:

BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/825468

By:

Sazonova, Margarita A.;
Sinyov, Vasily V.;
Barinova, Valeria A.;
Ryzhkova, Anastasia I.;
Zhelankin, Andrey V.;
Postnov, Anton Y.;
Sobenin, Igor A.;
Bobryshev, Yuri V.;
Orekhov, Alexander N.

Publication type:

Article

Low density lipoprotein-containing circulating immune complexes: role in atherosclerosis and diagnostic value.

Published in:

2014

By:

Sobenin, Igor A;
Salonen, Jukka T;
Zhelankin, Andrey V;
Melnichenko, Alexandra A;
Kaikkonen, Jari;
Bobryshev, Yuri V;
Orekhov, Alexander N

Publication type:

journal article

Role of endoplasmic reticulum stress in atherosclerosis and diabetic macrovascular complications.

Published in:

2014

By:

Chistiakov, Dmitry A;
Sobenin, Igor A;
Orekhov, Alexander N;
Bobryshev, Yuri V

Publication type:

Journal Article

Quantitative assessment of heteroplasmy of mitochondrial genome: perspectives in diagnostics and methodological pitfalls.

Published in:

2014

By:

Sobenin, Igor A;
Mitrofanov, Konstantin Y;
Zhelankin, Andrey V;
Sazonova, Margarita A;
Postnov, Anton Y;
Revin, Victor V;
Bobryshev, Yuri V;
Orekhov, Alexander N

Publication type:

Journal Article

Mitochondrial aging and age-related dysfunction of mitochondria.

Published in:

2014

By:

Chistiakov, Dimitry A;
Sobenin, Igor A;
Revin, Victor V;
Orekhov, Alexander N;
Bobryshev, Yuri V

Publication type:

Journal Article

Role of Endoplasmic Reticulum Stress in Atherosclerosis and Diabetic Macrovascular Complications.

Published in:

BioMed Research International, 2014, v. 2014, p. 1, doi. 10.1155/2014/610140

By:

Chistiakov, Dmitry A.;
Sobenin, Igor A.;
Orekhov, Alexander N.;
Bobryshev, Yuri V.

Publication type:

Article

Quantitative Assessment of Heteroplasmy of Mitochondrial Genome: Perspectives in Diagnostics and Methodological Pitfalls.

Published in:

BioMed Research International, 2014, v. 2014, p. 1, doi. 10.1155/2014/292017

By:

Sobenin, Igor A.;
Mitrofanov, Konstantin Y.;
Zhelankin, Andrey V.;
Sazonova, Margarita A.;
Postnov, Anton Y.;
Revin, Victor V.;
Bobryshev, Yuri V.;
Orekhov, Alexander N.

Publication type:

Article

Mitochondrial Aging and Age-Related Dysfunction of Mitochondria.

Published in:

BioMed Research International, 2014, v. 2014, p. 1, doi. 10.1155/2014/238463

By:

Chistiakov, Dimitry A.;
Sobenin, Igor A.;
Revin, Victor V.;
Orekhov, Alexander N.;
Bobryshev, Yuri V.

Publication type:

Article

Low-Density Lipoprotein Apheresis and Regression of Atherosclerotic Plaque In Vitro.

Published in:

Artificial Organs, 1986, v. 10, n. 6, p. 466, doi. 10.1111/j.1525-1594.1986.tb02605.x

By:

Orekhov, Alexander N.;
Khashimov, Khairulla A.;
Mukhin, Dmitry N.;
Tertov, Vladimir V.;
Adamova, Irina Yu.;
Pokrovsky, Sergei N.;
Smirnov, Vladimir N.

Publication type:

Article

Signaling Pathways and Key Genes Involved in Regulation of foam Cell Formation in Atherosclerosis.

Published in:

Cells (2073-4409), 2020, v. 9, n. 3, p. 584, doi. 10.3390/cells9030584

By:

Poznyak, Anastasia V.;
Wu, Wei-Kai;
Melnichenko, Alexandra A.;
Wetzker, Reinhard;
Sukhorukov, Vasily;
Markin, Alexander M.;
Khotina, Victoria A.;
Orekhov, Alexander N.

Publication type:

Article

Potential use of antioxidants for the treatment of chronic inflammatory diseases.

Published in:

Frontiers in Pharmacology, 2024, p. 01, doi. 10.3389/fphar.2024.1378335

By:

Blagov, Alexander V.;
Summerhill, Volha I.;
Sukhorukov, Vasily N.;
Zhigmitova, Elena B.;
Postnov, Anton Y.;
Orekhov, Alexander N.

Publication type:

Article

Commentary: PFKFB3 overexpression in monocytes of patients with colon but not rectal cancer programs pro-tumor macrophages and is indicative for higher risk of tumor relapse.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2023.1290459

By:

Shakhpazyan, Nikolay;
Mikhaleva, Liudmila;
Bedzhanyan, Arcady;
Sadykhov, Nikolay;
Midiber, Konstantin;
Orekhov, Alexander

Publication type:

Article

Decreased Expression of Liver X Receptor-α in Macrophages Infected with Chlamydia pneumoniae in Human Atherosclerotic Arteries in situ.

Published in:

Journal of Innate Immunity, 2011, v. 3, n. 5, p. 483, doi. 10.1159/000327522

By:

Bobryshev, Yuri V.;
Orekhov, Alexander N.;
Killingsworth, Murray C.;
Lu, Jinhua

Publication type:

Article

Pathophysiological Aspects of The Development of Abdominal Aortic Aneurysm with a Special Focus on Mitochondrial Dysfunction and Genetic Associations.

Published in:

Biomolecular Concepts, 2021, v. 12, n. 1, p. 55, doi. 10.1515/bmc-2021-0007

By:

Summerhil, Volha I.;
Sukhorukov, Vasily N.;
Eid, Ali H.;
Nedosugova, Ludmila V.;
Sobenin, Igor A.;
Orekhov, Alexander N.

Publication type:

Article

The role of mitochondrial dysfunction in cardiovascular disease: a brief review.

Published in:

Annals of Medicine, 2018, v. 50, n. 2, p. 121, doi. 10.1080/07853890.2017.1417631

By:

Chistiakov, Dimitry A.;
Shkurat, Tatiana P.;
Melnichenko, Alexandra A.;
Grechko, Andrey V.;
Orekhov, Alexander N.

Publication type:

Article

Role of lipids and intraplaque hypoxia in the formation of neovascularization in atherosclerosis.

Published in:

Annals of Medicine, 2017, v. 49, n. 8, p. 661, doi. 10.1080/07853890.2017.1366041

By:

Chistiakov, Dimitry A.;
Melnichenko, Alexandra A.;
Myasoedova, Veronika A.;
Grechko, Andrey V.;
Orekhov, Alexander N.

Publication type:

Article

Direct Anti-atherosclerosis-related Effects of Garlic.

Published in:

Annals of Medicine, 1995, v. 27, n. 1, p. 63, doi. 10.3109/07853899509031938

By:

Orekhov, Alexander N.;
Tertov, Vladimir V.;
Sobenin, Igor A.;
Pivovarova, Elena M.

Publication type:

Article

Association of Mitochondrial Genetic Variation with Carotid Atherosclerosis.

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068070

By:

Sobenin, Igor A.;
Sazonova, Margarita A.;
Postnov, Anton Y.;
Salonen, Jukka T.;
Bobryshev, Yuri V.;
Orekhov, Alexander N.

Publication type:

Article

Lipid Regulators during Atherogenesis: Expression of LXR, PPAR, and SREBP mRNA in the Human Aorta

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063374

By:

Shchelkunova, Tatyana A.;
Morozov, Ivan A.;
Rubtsov, Petr M.;
Bobryshev, Yuri V.;
Sobenin, Igor A.;
Orekhov, Alexander N.;
Andrianova, Irina V.;
Smirnov, Alexander N.

Publication type:

Article

Mutation C3256T of Mitochondrial Genome in White Blood Cells: Novel Genetic Marker of Atherosclerosis and Coronary Heart Disease.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046573

By:

Sobenin, Igor A.;
Sazonova, Margarita A.;
Ivanova, Maria M.;
Zhelankin, Andrey V.;
Myasoedova, Veronika A.;
Postnov, Anton Y.;
Nurbaev, Serik D.;
Bobryshev, Yuri V.;
Orekhov, Alexander N.;
Zeller, Tanja

Publication type:

Article

Comparative study of the pharmacokinetic parameters for salidroside in normal and estrogen-deficient female rats after oral administration of an aqueous extract of Fructus Ligustri Lucidi using a validated ultra-performance liquid chromatography mass spectrometry/mass spectrometry method

Published in:

Pharmacognosy Magazine, 2020, v. 16, n. 71, p. 471, doi. 10.4103/pm.pm_278_19

By:

Chen, Beibei;
Tang, Jinfa;
Niu, Ming;
Zhu, Ruyuan;
Li, Lin;
Wang, Lili;
Tian, Yimiao;
Li, Rui;
Jia, Qiangqiang;
Zhao, Dandan;
Mo, Fangfang;
Romanenko, Elena;
Orekhov, Alexander;
Gao, Sihua;
Brömme, Dieter;
Zhang, Dongwei

Publication type:

Article

LDL electronegativity index: a potential novel index for predicting cardiovascular disease.

Published in:

2015

By:

Ivanova, Ekaterina A.;
Bobryshev, Yuri V.;
Orekhov, Alexander N.

Publication type:

journal article

The complexity of cell composition of the intima of large arteries: focus on pericyte-like cells.

Published in:

Cardiovascular Research, 2014, v. 103, n. 4, p. 438, doi. 10.1093/cvr/cvu168

By:

Orekhov, Alexander N.;
Bobryshev, Yuri V.;
Chistiakov, Dimitry A.

Publication type:

Article

Atherogenic modified LDL in diabetes.

Published in:

1996

By:

Sobenin, Igor A.;
Tertov, Vladimir V.;
Orekhov, Alexander N.;
Sobenin, I A;
Tertov, V V;
Orekhov, A N

Publication type:

journal article

Antiatherogenic and antiatherosclerotic effects of mushroom extracts revealed in human aortic intima cell culture.

Published in:

Drug Development Research, 1989, v. 17, n. 2, p. 109, doi. 10.1002/ddr.430170203

By:

Ryong, Li Hwa;
Tertov, Vladimir V.;
Vasil'ev, Andrew V.;
Tutel'yan, Victor A.;
Orekhov, Alexander N.

Publication type:

Article

'Regression' of atherosclerosis in cell culture: Effects of stable prostacyclin analogues.

Published in:

Drug Development Research, 1986, v. 9, n. 3, p. 189, doi. 10.1002/ddr.430090303

By:

Orekhov, Alexander N.;
Tertov, Vladimir V.;
Mazurov, Aleksey V.;
Andreeva, Elena R.;
Repin, Vadim S.;
Smirnov, Vladimir N.

Publication type:

Article

Mutations of mitochondrial genome in carotid atherosclerosis.

Published in:

Frontiers in Genetics, 2015, v. 6, p. 1, doi. 10.3389/fgene.2015.00111

By:

Sazonova, Margarita A.;
Zhelankin, Andrey V.;
Barinova, Valeria A.;
Sinyov, Vasily V.;
Khasanova, Zukhra B.;
Postnov, Anton Y.;
Orekhov, Alexander N.;
Bobryshev, Yuri V.;
Soben, Igor A.

Publication type:

Article

The Interaction of Plasma Sialylated and Desialylated Lipoproteins with Collagen fromthe Intima andMedia of Uninvolved and Atherosclerotic Human Aorta.

Published in:

Journal of Lipids, 2011, p. 1, doi. 10.1155/2011/254267

By:

Sobenin, Igor A.;
Suprun, Igor V.;
Karagodin, Vasiliy P.;
Feoktistov, Alexander S.;
Melnichenko, Alexandra A.;
Orekhov, Alexander N.

Publication type:

Article

Sex Differences Define the Vulnerability to Atherosclerosis.

Published in:

Clinical Medicine Insights: Cardiology, 2023, p. 1, doi. 10.1177/11795468231189044

By:

Poznyak, Anastasia V;
Sukhorukov, Vasiliy N;
Guo, Shuzhen;
Postnov, Anton Y;
Orekhov, Alexander N

Publication type:

Article

Development of Antiatherosclerotic Drugs on the basis of Natural Products Using Cell Model Approach.

Published in:

Oxidative Medicine & Cellular Longevity, 2015, v. 2015, p. 1, doi. 10.1155/2015/463797

By:

Orekhov, Alexander N.;
Sobenin, Igor A.;
Revin, Victor V.;
Bobryshev, Yuri V.

Publication type:

Article

Approach to Reduction of Blood Atherogenicity.

Published in:

Oxidative Medicine & Cellular Longevity, 2014, v. 2014, p. 1, doi. 10.1155/2014/738679

By:

Orekhov, Alexander N.;
Melnichenko, Alexandra A.;
Sobenin, Igor A.

Publication type:

Article

Inhibition of sialidase activity as a therapeutic approach.

Published in:

Drug Design, Development & Therapy, 2018, v. 12, p. 3431, doi. 10.2147/DDDT.S176220

By:

Glanz, Victor Yu;
Myasoedova, Veronika A;
Grechko, Andrey V;
Orekhov, Alexander N

Publication type:

Article