Works by O’Keeffe, Gerard W.

Results: 47

Association of Hypertensive Disorders of Pregnancy With Risk of Neurodevelopmental Disorders in Offspring: A Systematic Review and Meta-analysis.

Published in:

2018

By:

Maher, Gillian M.;
O’Keeffe, Gerard W.;
Kearney, Patricia M.;
Kenny, Louise C.;
Dinan, Timothy G.;
Mattsson, Molly;
Khashan, Ali S.;
O'Keeffe, Gerard W

Publication type:

journal article

Placental FKBP51 mediates a link between second trimester maternal anxiety and birthweight in female infants.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33357-3

By:

Togher, Katie L.;
O’Keeffe, Gerard W.;
Khashan, Ali S.;
Clarke, Gerard;
Kenny, Louise C.

Publication type:

Article

An altered gut microbiome in pre-eclampsia: cause or consequence.

Published in:

Frontiers in Cellular & Infection Microbiology, 2024, p. 01, doi. 10.3389/fcimb.2024.1352267

By:

Deady, Clara;
McCarthy, Fergus P.;
Barron, Aaron;
McCarthy, Cathal M.;
O'Keeffe, Gerard W.;
O'Mahony, Siobhain M.

Publication type:

Article

The spatial and temporal arrangement of the radial glial scaffold suggests a role in axon tract formation in the developing spinal cord.

Published in:

Journal of Anatomy, 2013, v. 222, n. 2, p. 203, doi. 10.1111/joa.12006

By:

Barry, Denis S.;
Pakan, Janelle M. P.;
O'Keeffe, Gerard W.;
McDermott, Kieran W.

Publication type:

Article

The role of growth/differentiation factor 5 (GDF5) in the induction and survival of midbrain dopaminergic neurones: relevance to Parkinson's disease treatment.

Published in:

Journal of Anatomy, 2005, v. 207, n. 3, p. 219, doi. 10.1111/j.1469-7580.2005.00447.x

By:

Sullivan, Aideen M.;
O'Keeffe, Gerard W.

Publication type:

Article

Human α‐synuclein overexpression upregulates SKOR1 in a rat model of simulated nigrostriatal ageing.

Published in:

Aging Cell, 2024, v. 23, n. 6, p. 1, doi. 10.1111/acel.14155

By:

Morales‐Prieto, Noelia;
Bevans, Rebekah;
O'Mahony, Adam;
Barron, Aaron;
Giles Doran, Conor;
McCarthy, Erin;
Concannon, Ruth M.;
Goulding, Susan R.;
McCarthy, Cathal M.;
Collins, Louise M.;
Sullivan, Aideen M.;
O'Keeffe, Gerard W.

Publication type:

Article

Mid-gestation cytokine profiles in mothers of children affected by autism spectrum disorder: a case–control study.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-01662-z

By:

Carter, Michael;
Casey, Sophie;
O'Keeffe, Gerard W.;
Gibson, Louise;
Murray, Deirdre M.

Publication type:

Article

Class-Specific Histone Deacetylase Inhibitors Promote 11-Beta Hydroxysteroid Dehydrogenase Type 2 Expression in JEG-3 Cells.

Published in:

International Journal of Cell Biology, 2017, p. 1, doi. 10.1155/2017/6169310

By:

Togher, Katie L.;
Kenny, Louise C.;
O’Keeffe, Gerard W.

Publication type:

Article

The Effect of Hypertensive Disorders of Pregnancy on the Risk of ADHD in the Offspring.

Published in:

2019

By:

Böhm, Stefanie;
Curran, Eileen A.;
Kenny, Louise C.;
O'Keeffe, Gerard W.;
Murray, Deirdre;
Khashan, Ali S.

Publication type:

journal article

Knockdown of interleukin-1 receptor 1 is not neuroprotective in the 6-hydroxydopamine striatal lesion rat model of Parkinson's disease.

Published in:

International Journal of Neuroscience, 2015, v. 125, n. 1, p. 70, doi. 10.3109/00207454.2014.904304

By:

Walsh, Sinéad;
Gavin, Aisling;
Wyatt, Séan;
O'Connor, Catriona;
Keeshan, Karen;
Nolan, Yvonne M.;
O'Keeffe, Gerard W.;
Sullivan, Aideen M.

Publication type:

Article

Alpha-synuclein-induced upregulation of SKI family transcriptional corepressor 1: A new player in aging and Parkinson's disease?

Published in:

Neural Regeneration Research, 2026, v. 21, n. 1, p. 320, doi. 10.4103/NRR.NRR-D-24-01156

By:

Barrett, Lauren;
Bevans, Rebekah;
Sullivan, Aideen M.;
Collins, Louise M.;
O'Keeffe, Gerard W.

Publication type:

Article

Growth differentiation factor 5: a neurotrophic factor with neuroprotective potential in Parkinson's disease.

Published in:

Neural Regeneration Research, 2022, v. 17, n. 1, p. 38, doi. 10.4103/1673-5374.314290

By:

Goulding, Susan R.;
Anantha, Jayanth;
Collins, Louise M.;
Sullivan, Aideen M.;
O'Keeffe, Gerard W.

Publication type:

Article

Growth differentiation factor 5 exerts neuroprotection in an α-synuclein rat model of Parkinson's disease.

Published in:

2021

By:

Goulding, Susan R;
Concannon, Ruth M;
Morales-Prieto, Noelia;
Villalobos-Manriquez, Francisca;
Clarke, Gerard;
Collins, Louise M;
Lévesque, Martin;
Wyatt, Sean L;
Sullivan, Aideen M;
O'Keeffe, Gerard W

Publication type:

Letter

Regulation of axonal and dendritic growth by the extracellular calcium-sensing receptor.

Published in:

Nature Neuroscience, 2008, v. 11, n. 3, p. 285, doi. 10.1038/nn2044

By:

Vizard, Thomas N.;
O'Keeffe, Gerard W.;
Gutierrez, Humberto;
Kos, Claudine H.;
Riccardi, Daniela;
Davies, Alun M.

Publication type:

Article

NGF-promoted axon growth and target innervation requires GITRL-GITR signaling.

Published in:

Nature Neuroscience, 2008, v. 11, n. 2, p. 135, doi. 10.1038/nn2034

By:

O'Keeffe, Gerard W.;
Gutierrez, Humberto;
Pandolfi, Pier Paolo;
Riccardi, Carlo;
Davies, Alun M.

Publication type:

Article

Maternal Immune Activation and Interleukin 17A in the Pathogenesis of Autistic Spectrum Disorder and Why It Matters in the COVID-19 Era.

Published in:

Frontiers in Psychiatry, 2022, v. 13, p. 1, doi. 10.3389/fpsyt.2022.823096

By:

Carter, Michael;
Casey, Sophie;
O'Keeffe, Gerard W.;
Gibson, Louise;
Gallagher, Louise;
Murray, Deirdre M.

Publication type:

Article

The association between caesarean section and cognitive ability in childhood.

Published in:

2020

By:

Hanrahan, Michael;
McCarthy, Fergus P.;
O'Keeffe, Gerard W.;
Khashan, Ali S.

Publication type:

journal article

Prenatal maternal stress and risk of neurodevelopmental disorders in the offspring: a systematic review and meta-analysis.

Published in:

2019

By:

Manzari, Nicla;
Matvienko-Sikar, Karen;
Baldoni, Franco;
O'Keeffe, Gerard W.;
Khashan, Ali S.

Publication type:

journal article

Gene Co-expression Analysis of the Human Substantia Nigra Identifies ZNHIT1 as an SNCA Co-expressed Gene that Protects Against α-Synuclein-Induced Impairments in Neurite Growth and Mitochondrial Dysfunction in SH-SY5Y Cells.

Published in:

Molecular Neurobiology, 2022, v. 59, n. 5, p. 2745, doi. 10.1007/s12035-022-02768-9

By:

McCarthy, Erin;
Barron, Aaron;
Morales-Prieto, Noelia;
Mazzocchi, Martina;
McCarthy, Cathal M.;
Collins, Louise M.;
Sullivan, Aideen M.;
O'Keeffe, Gerard W.

Publication type:

Article

NME1 Protects Against Neurotoxin-, α-Synuclein- and LRRK2-Induced Neurite Degeneration in Cell Models of Parkinson's Disease.

Published in:

Molecular Neurobiology, 2022, v. 59, n. 1, p. 61, doi. 10.1007/s12035-021-02569-6

By:

Anantha, Jayanth;
Goulding, Susan R.;
Tuboly, Eszter;
O'Mahony, Adam G.;
Moloney, Gerard M.;
Lomansey, Gareth;
McCarthy, Cathal M.;
Collins, Louise M.;
Sullivan, Aideen M.;
O'Keeffe, Gerard W.

Publication type:

Article

Quinacrine and Niclosamide Promote Neurite Growth in Midbrain Dopaminergic Neurons Through the Canonical BMP-Smad Pathway and Protect Against Neurotoxin and α-Synuclein-Induced Neurodegeneration.

Published in:

Molecular Neurobiology, 2021, v. 58, n. 7, p. 3405, doi. 10.1007/s12035-021-02351-8

By:

Goulding, Susan R.;
Lévesque, Martin;
Sullivan, Aideen M.;
Collins, Louise M.;
O'Keeffe, Gerard W.

Publication type:

Article

Preeclampsia and Neurodevelopmental Outcomes: Potential Pathogenic Roles for Inflammation and Oxidative Stress?

Published in:

Molecular Neurobiology, 2021, v. 58, n. 6, p. 2734, doi. 10.1007/s12035-021-02290-4

By:

Barron, Aaron;
McCarthy, Cathal M.;
O'Keeffe, Gerard W.

Publication type:

Article

Temporally Altered miRNA Expression in a Piglet Model of Hypoxic Ischemic Brain Injury.

Published in:

Molecular Neurobiology, 2020, v. 57, n. 10, p. 4322, doi. 10.1007/s12035-020-02018-w

By:

Casey, Sophie;
Goasdoue, Kate;
Miller, Stephanie M.;
Brennan, Gary P.;
Cowin, Gary;
O'Mahony, Adam G.;
Burke, Christopher;
Hallberg, Boubou;
Boylan, Geraldine B.;
Sullivan, Aideen M.;
Henshall, David C.;
O'Keeffe, Gerard W.;
Mooney, Catherine;
Bjorkman, Tracey;
Murray, Deirdre M.

Publication type:

Article

Exposure to Hypertensive Disorders of Pregnancy Increases the Risk of Autism Spectrum Disorder in Affected Offspring.

Published in:

Molecular Neurobiology, 2018, v. 55, n. 7, p. 5557, doi. 10.1007/s12035-017-0794-x

By:

Curran, Eileen A.;
O’Keeffe, Gerard W.;
Looney, Ann Marie;
Moloney, Gerard;
Hegarty, Shane V.;
Murray, Deirdre M.;
Khashan, Ali S.;
Kenny, Louise C.

Publication type:

Article

Simulated ischaemia/reperfusion impairs trophoblast function through divergent oxidative stress- and MMP-9-dependent mechanisms.

Published in:

Bioscience Reports, 2024, v. 44, n. 11, p. 1, doi. 10.1042/BSR20240763

By:

Barron, Aaron;
Tuulari, Jetro J.;
Karlsson, Linnea;
Karlsson, Hasse;
O’Keeffe, Gerard W.;
McCarthy, Cathal M.

Publication type:

Article

sFlt-1 impairs neurite growth and neuronal differentiation in SH-SY5Y cells and human neurons.

Published in:

Bioscience Reports, 2024, v. 44, n. 5, p. 1, doi. 10.1042/BSR20240562

By:

Barron, Aaron;
Barrett, Lauren;
Tuulari, Jetro J.;
Karlsson, Linnea;
Karlsson, Hasse;
McCarthy, Cathal M.;
O'Keeffe, Gerard W.

Publication type:

Article

Region-specific role of growth differentiation factor-5 in the establishment of sympathetic innervation.

Published in:

Neural Development, 2016, v. 11, p. 1, doi. 10.1186/s13064-016-0060-3

By:

O'Keeffe, Gerard W.;
Gutierrez, Humberto;
Howard, Laura;
Laurie, Christopher W.;
Osorio, Catarina;
Gavaldà, Núria;
Wyatt, Sean L.;
Davies, Alun M.

Publication type:

Article

Nerve growth factor-mediated regulation of pain signalling and proposed new intervention strategies in clinical pain management.

Published in:

Journal of Neurochemistry, 2013, v. 124, n. 3, p. 276, doi. 10.1111/jnc.12093

By:

McKelvey, Laura;
Shorten, George D.;
O'Keeffe, Gerard W.

Publication type:

Article

Exposure of foetal neural progenitor cells to IL-1β impairs their proliferation and alters their differentiation - a role for maternal inflammation?

Published in:

Journal of Neurochemistry, 2012, v. 120, n. 6, p. 964, doi. 10.1111/j.1471-4159.2011.07634.x

By:

Crampton, Sean J.;
Collins, Louise M.;
Toulouse, Andre;
Nolan, Yvonne M.;
O'Keeffe, Gerard W.

Publication type:

Article

Bioinformatics and Immunohistochemical Analyses Support Preserved Expression of Glial Cell Line–Derived Neurotrophic Factor Receptor RET in Parkinson's.

Published in:

Movement Disorders, 2023, v. 38, n. 6, p. 1115, doi. 10.1002/mds.29443

By:

Giles Doran, Conor;
Wilson, Fionnuala;
Goulding, Susan R.;
Mazzocchi, Martina;
Collins, Louise M.;
Sullivan, Aideen M.;
O'Keeffe, Gerard W.

Publication type:

Article

A perspective on pre-eclampsia and neurodevelopmental outcomes in the offspring: Does maternal inflammation play a role?

Published in:

International Journal of Developmental Neuroscience, 2019, v. 77, p. 69, doi. 10.1016/j.ijdevneu.2018.10.004

By:

Maher, Gillian M.;
McCarthy, Fergus P.;
McCarthy, Cathal M.;
Kenny, Louise C.;
Kearney, Patricia M.;
Khashan, Ali S.;
O'Keeffe, Gerard W.

Publication type:

Article

Regulator of G‐Protein Signalling 4 (RGS4) negatively modulates nociceptin/orphanin FQ opioid receptor signalling: Implication for l‐Dopa‐induced dyskinesia.

Published in:

British Journal of Pharmacology, 2023, v. 180, n. 7, p. 927, doi. 10.1111/bph.15730

By:

Pisanò, Clarissa A.;
Mercatelli, Daniela;
Mazzocchi, Martina;
Brugnoli, Alberto;
Morella, Ilaria;
Fasano, Stefania;
Zaveri, Nurulain T.;
Brambilla, Riccardo;
O'Keeffe, Gerard W.;
Neubig, Richard R.;
Morari, Michele

Publication type:

Article

The Universal Design for Learning Framework in Anatomical Sciences Education.

Published in:

Anatomical Sciences Education, 2021, v. 14, n. 1, p. 71, doi. 10.1002/ase.1992

By:

Balta, Joy Y.;
Supple, Briony;
O'Keeffe, Gerard W.

Publication type:

Article

Googling in anatomy education: Can google trends inform educators of national online search patterns of anatomical syllabi?

Published in:

Anatomical Sciences Education, 2017, v. 10, n. 2, p. 152, doi. 10.1002/ase.1641

By:

Phelan, Nigel;
Davy, Shane;
O'Keeffe, Gerard W.;
Barry, Denis S.

Publication type:

Article

The need for ethical and pedagogical frameworks for developing online media in anatomy education.

Published in:

Anatomical Sciences Education, 2016, v. 9, n. 5, p. 498, doi. 10.1002/ase.1628

By:

Barry, Denis S.;
Tierney, Paul;
O'Keeffe, Gerard W.

Publication type:

Article

Cadaveric anatomy in the future of medical education: What is the surgeons view?

Published in:

Anatomical Sciences Education, 2016, v. 9, n. 2, p. 203, doi. 10.1002/ase.1560

By:

Sheikh, Ahmad Hassan;
Barry, Denis S.;
Gutierrez, Humberto;
Cryan, John F.;
O'Keeffe, Gerard W.

Publication type:

Article

Anatomy education for the YouTube generation.

Published in:

Anatomical Sciences Education, 2016, v. 9, n. 1, p. 90, doi. 10.1002/ase.1550

By:

Barry, Denis S.;
Marzouk, Fadi;
Chulak ‐ Oglu, Kyrylo;
Bennett, Deirdre;
Tierney, Paul;
O'Keeffe, Gerard W.

Publication type:

Article

Characterisation of the consequences of maternal immune activation on distinct cell populations in the developing rat spinal cord.

Published in:

Journal of Anatomy, 2022, v. 241, n. 4, p. 938, doi. 10.1111/joa.13726

By:

Anderson, Rebecca C.;
O'Keeffe, Gerard W.;
McDermott, Kieran W.

Publication type:

Article

The distribution of the proteoglycan FORSE‐1 in the developing mouse central nervous system.

Published in:

Journal of Anatomy, 2019, v. 234, n. 2, p. 216, doi. 10.1111/joa.12907

By:

Kelly, Albert;
O'Malley, Aisling;
Redha, Mohammad;
O'Keeffe, Gerard W.;
Barry, Denis S.

Publication type:

Article

Transplantation of novel human GDF5-expressing CHO cells is neuroprotective in models of Parkinson's disease.

Published in:

Journal of Cellular & Molecular Medicine, 2012, v. 16, n. 10, p. 2451, doi. 10.1111/j.1582-4934.2012.01562.x

By:

Costello, Daniel J.;
O'Keeffe, Gerard W.;
Hurley, Fiona M.;
Sullivan, Aideen M.

Publication type:

Article

Editorial: The Role of Stem Cells, Epigenetics and MicroRNAs in Parkinson's Disease.

Published in:

2020

By:

Hegarty, Shane V.;
Green, Holly F.;
Niclis, Jonathan;
O'Keeffe, Gerard W.;
Sullivan, Aideen M.

Publication type:

Editorial

Diet quality, sleep and quality of life in Parkinson's disease: a cross-sectional study.

Published in:

Irish Journal of Medical Science, 2023, v. 192, n. 3, p. 1371, doi. 10.1007/s11845-022-03144-1

By:

Dunk, Danielle;
Mulryan, Philip;
Affonso, Sean;
O'Keeffe, Gerard W.;
O'Keeffe, Majella;
Sullivan, Aideen M.

Publication type:

Article

4-Hydroxychalcone Induces Cell Death via Oxidative Stress in MYCN-Amplified Human Neuroblastoma Cells.

Published in:

Oxidative Medicine & Cellular Longevity, 2019, p. 1, doi. 10.1155/2019/1670759

By:

Alshangiti, Amnah M.;
Tuboly, Eszter;
Hegarty, Shane V.;
McCarthy, Cathal M.;
Sullivan, Aideen M.;
O'Keeffe, Gerard W.

Publication type:

Article

The Association Between Preeclampsia and Childhood Development and Behavioural Outcomes.

Published in:

Maternal & Child Health Journal, 2020, v. 24, n. 6, p. 727, doi. 10.1007/s10995-020-02921-7

By:

Maher, Gillian M.;
O'Keeffe, Gerard W.;
O'Keeffe, Linda M.;
Matvienko-Sikar, Karen;
Dalman, Christina;
Kearney, Patricia M.;
McCarthy, Fergus P.;
Khashan, Ali S.

Publication type:

Article

Association between preeclampsia and autism spectrum disorder: a population‐based study.

Published in:

Journal of Child Psychology & Psychiatry, 2020, v. 61, n. 2, p. 131, doi. 10.1111/jcpp.13127

By:

Maher, Gillian M.;
O'Keeffe, Gerard W.;
Dalman, Christina;
Kearney, Patricia M.;
McCarthy, Fergus P.;
Kenny, Louise C.;
Khashan, Ali S.

Publication type:

Article

Epigenetic regulation of the placental HSD11B2 barrier and its role as a critical regulator of fetal development.

Published in:

Epigenetics, 2014, v. 9, n. 6, p. 816, doi. 10.4161/epi.28703

By:

Togher, Katie L.;
O'Keeffe, Majella M.;
Khashan, Ali S.;
Gutierrez, Humberto;
Kenny, Louise C.;
O'Keeffe, Gerard W.

Publication type:

Article

Nuclear Factor κB Signaling Either Stimulates or Inhibits Neurite Growth Depending on the Phosphorylation Status of p65/RelA.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 33, p. 8246, doi. 10.1523/JNEUROSCI.1941-08.2008

By:

Gutierrez, Humberto;
O'Keeffe, Gerard W.;
Gavalda, Núria;
Gallagher, Denis;
Davies, Alun M.

Publication type:

Article