Works by O'Hagan, Derek T.

Results: 34

Combination Vaccines.

Published in:

Journal of Global Infectious Diseases, 2011, v. 3, n. 1, p. 63, doi. 10.4103/0974-777X.77298

By:

Skibinski, David AG;
Baudner, Barbara C.;
Singh, Manmohan;
O'Hagan, Derek T.

Publication type:

Article

Aluminum Adjuvants—'Back to the Future'.

Published in:

Pharmaceutics, 2023, v. 15, n. 7, p. 1884, doi. 10.3390/pharmaceutics15071884

By:

Laera, Donatello;
HogenEsch, Harm;
O'Hagan, Derek T.

Publication type:

Article

A Self-Emulsified Adjuvant System Containing the Immune Potentiator Alpha Tocopherol Induces Higher Neutralizing Antibody Responses than a Squalene-Only Emulsion When Evaluated with a Recombinant Cytomegalovirus (CMV) Pentamer Antigen in Mice.

Published in:

Pharmaceutics, 2023, v. 15, n. 1, p. 238, doi. 10.3390/pharmaceutics15010238

By:

Lodaya, Rushit N.;
Kanitkar, Amey P.;
Ashraf, Asma;
Bamba, Douty;
Amiji, Mansoor M.;
O'Hagan, Derek T.

Publication type:

Article

Conjugation of Mannans to Enhance the Potency of Liposome Nanoparticles for the Delivery of RNA Vaccines.

Published in:

Pharmaceutics, 2021, v. 13, n. 2, p. 240, doi. 10.3390/pharmaceutics13020240

By:

Goswami, Roshan;
O'Hagan, Derek T.;
Adamo, Roberto;
Baudner, Barbara C.;
Marasini, Nirmal

Publication type:

Article

Microfluidic-Chip-Based Formulation and In Vivo Evaluations of Squalene Oil Emulsion Adjuvants for Subunit Vaccines.

Published in:

Vaccines, 2024, v. 12, n. 12, p. 1343, doi. 10.3390/vaccines12121343

By:

Bhangde, Shashank;
Fresnay-Murray, Stephanie;
Garretson, Tyler;
Ashraf, Asma;
O'Hagan, Derek T.;
Amiji, Mansoor M.;
Lodaya, Rushit N.

Publication type:

Article

Maturation of Aluminium Adsorbed Antigens Contributes to the Creation of Homogeneous Vaccine Formulations.

Published in:

Vaccines, 2023, v. 11, n. 1, p. 155, doi. 10.3390/vaccines11010155

By:

Laera, Donatello;
Scarpellini, Camilla;
Tavarini, Simona;
Baudner, Barbara;
Marcelli, Agnese;
Pergola, Carlo;
Meppen, Malte;
O'Hagan, Derek T.

Publication type:

Article

Investigating the Impact of Delivery System Design on the Efficacy of Self-Amplifying RNA Vaccines.

Published in:

Vaccines, 2020, v. 8, n. 2, p. 212, doi. 10.3390/vaccines8020212

By:

Anderluzzi, Giulia;
Lou, Gustavo;
Gallorini, Simona;
Brazzoli, Michela;
Johnson, Russell;
O'Hagan, Derek T.;
Baudner, Barbara C.;
Perrie, Yvonne

Publication type:

Article

The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses.

Published in:

European Journal of Immunology, 2012, v. 42, n. 10, p. 2709, doi. 10.1002/eji.201242372

By:

Mori, Andres;
Oleszycka, Ewa;
Sharp, Fiona A.;
Coleman, Michelle;
Ozasa, Yuki;
Singh, Manmohan;
O'Hagan, Derek T.;
Tajber, Lidia;
Corrigan, Owen I.;
McNeela, Edel A.;
Lavelle, Ed C.

Publication type:

Article

Author Correction: "World in motion" – emulsion adjuvants rising to meet the pandemic challenges.

Published in:

2023

By:

O'Hagan, Derek T.;
van der Most, Robbert;
Lodaya, Rushit N.;
Coccia, Margherita;
Lofano, Giuseppe

Publication type:

Correction Notice

"World in motion" – emulsion adjuvants rising to meet the pandemic challenges.

Published in:

NPJ Vaccines, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41541-021-00418-0

By:

O'Hagan, Derek T.;
van der Most, Robbert;
Lodaya, Rushit N.;
Coccia, Margherita;
Lofano, Giuseppe

Publication type:

Article

Emulsion based vaccine adjuvants.

Published in:

Human Vaccines & Immunotherapeutics, 2013, v. 9, n. 8, p. 1, doi. 10.4161/hv.24829

By:

O'Hagan, Derek T.;
Tsai, Tedodore F.;
Brito, Luis A.

Publication type:

Article

MF59 oil-in-water emulsion in combination with a synthetic TLR4 agonist (E6020) is a potent adjuvant for a combination Meningococcus vaccine.

Published in:

Human Vaccines & Immunotherapeutics, 2012, v. 8, n. 4, p. 486, doi. 10.4161/hv.19229

By:

Singh, Manmohan;
Kazzaz, Jina;
Ugozzoli, Mildred;
Baudner, Barbara;
Pizza, Mariagrazia;
Giuliani, Marzia;
Hawkins, Lynn D.;
Otten, Gillis;
O'hagan, Derek T.

Publication type:

Article

Vaccine priming is restricted to draining lymph nodes and controlled by adjuvant-mediated antigen uptake.

Published in:

Science Translational Medicine, 2017, v. 9, n. 393, p. 1, doi. 10.1126/scitranslmed.aal2094

By:

Liang, Frank;
Lindgren, Gustaf;
Sandgren, Kerrie J.;
Thompson, Elizabeth A.;
Francica, Joseph R.;
Seubert, Anja;
De Gregorio, Ennio;
Barnett, Susan;
O'Hagan, Derek T.;
Sullivan, Nancy J.;
Koup, Richard A.;
Seder, Robert A.;
Loré, Karin

Publication type:

Article

Mechanism of action of mRNA-based vaccines.

Published in:

Expert Review of Vaccines, 2017, v. 16, n. 9, p. 871, doi. 10.1080/14760584.2017.1355245

By:

Iavarone, Carlo;
O’hagan, Derek T.;
Yu, Dong;
Delahaye, Nicolas F.;
Ulmer, Jeffrey B.

Publication type:

Article

Are we entering a new age for human vaccine adjuvants?

Published in:

Expert Review of Vaccines, 2015, v. 14, n. 7, p. 909, doi. 10.1586/14760584.2015.1043273

By:

O'Hagan, Derek T;
Fox, Christopher B

Publication type:

Article

The history of MF59® adjuvant: a phoenix that arose from the ashes.

Published in:

Expert Review of Vaccines, 2013, v. 12, n. 1, p. 13, doi. 10.1586/ERV.12.140

By:

O'Hagan, Derek T.;
Ott, Gary S.;
Van Nest, Gary;
Rappuoli, Rino;
Del Giudice, Giuseppe

Publication type:

Article

MF59 is a safe and potent vaccine adjuvant that enhances protection against influenza virus infection.

Published in:

Expert Review of Vaccines, 2007, v. 6, n. 5, p. 699, doi. 10.1586/14760584.6.5.699

By:

O'Hagan, Derek T.

Publication type:

Article

Adjuvants: progress, regress and pandemic preparedness.

Published in:

Expert Review of Vaccines, 2007, v. 6, n. 5, p. 651, doi. 10.1586/14760584.6.5.651

By:

Glenn, Gregory M.;
O'Hagan, Derek T.

Publication type:

Article

Microparticles for the delivery of DNA vaccines.

Published in:

Immunological Reviews, 2004, v. 199, n. 1, p. 191, doi. 10.1111/j.0105-2896.2004.00153.x

By:

O'Hagan, Derek T.;
Singh, Manmohan;
Ulmer, Jeffrey B.

Publication type:

Article

The droplet size of emulsion adjuvants has significant impact on their potency, due to differences in immune cell-recruitment and -activation.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47885-z

By:

Shah, Ruchi R.;
Taccone, Marianna;
Monaci, Elisabetta;
Brito, Luis A.;
Bonci, Alessandra;
O'Hagan, Derek T.;
Amiji, Mansoor M.;
Seubert, Anja

Publication type:

Article

Microreview Innate immunity and biodefence vaccines.

Published in:

Cellular Microbiology, 2003, v. 5, n. 11, p. 755, doi. 10.1046/j.1462-5822.2003.00318.x

By:

Valiante, Nicholas M.;
O'Hagan, Derek T.;
Ulmer, Jeffery B.

Publication type:

Article

The scientific journey of a novel adjuvant (AS37) from bench to bedside.

Published in:

NPJ Vaccines, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41541-024-00810-6

By:

D'Oro, Ugo;
O'Hagan, Derek T.

Publication type:

Article

A Cationic Nanoemulsion for the Delivery of Next-generation RNA Vaccines.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2118, doi. 10.1038/mt.2014.133

By:

Brito, Luis A;
Chan, Michelle;
Shaw, Christine A;
Hekele, Armin;
Carsillo, Thomas;
Schaefer, Mary;
Archer, Jacob;
Seubert, Anja;
Otten, Gillis R;
Beard, Clayton W;
Dey, Antu K;
Lilja, Anders;
Valiante, Nicholas M;
Mason, Peter W;
Mandl, Christian W;
Barnett, Susan W;
Dormitzer, Philip R;
Ulmer, Jeffrey B;
Singh, Manmohan;
O'Hagan, Derek T

Publication type:

Article

β7-integrin-independent enhancement of mucosal and systemic anti-HIV antibody responses following combined mucosal and systemic gene delivery.

Published in:

Immunology, 2008, v. 123, n. 3, p. 378, doi. 10.1111/j.1365-2567.2007.02702.x

By:

Goodsell, Amanda;
Zhou, Fengmin;
Gupta, Soumi;
Singh, Manmohan;
Malyala, Padma;
Kazzaz, Jina;
Greer, Catherine;
Legg, Harold;
Tang, Tony;
zur Megede, January;
Srivastava, Ranjana;
Barnett, Susan W.;
Donnelly, John J.;
Luciw, Paul A.;
Polo, John;
O'Hagan, Derek T.;
Vajdy, Michael

Publication type:

Article

Recent advances in the discovery and delivery of vaccine adjuvants.

Published in:

2003

By:

O'Hagan, Derek T.;
Valiante, Nicholas M.

Publication type:

journal article

Technological approaches to streamline vaccination schedules, progressing towards single-dose vaccines.

Published in:

NPJ Vaccines, 2020, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41541-020-00238-8

By:

Lofano, Giuseppe;
Mallett, Corey P.;
Bertholet, Sylvie;
O'Hagan, Derek T.

Publication type:

Article

Optimizing the utilization of aluminum adjuvants in vaccines: you might just get what you want.

Published in:

NPJ Vaccines, 2018, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41541-018-0089-x

By:

HogenEsch, Harm;
O'Hagan, Derek T.;
Fox, Christopher B.

Publication type:

Article

Bioadhesive delivery systems for mucosal vaccine delivery.

Published in:

Journal of Drug Targeting, 2010, v. 18, n. 10, p. 752, doi. 10.3109/1061186X.2010.529143

By:

Baudner, Barbara C.;
O'Hagan, Derek T.

Publication type:

Article

Comparison of Poly( dl -Lactide-co-glycolide) and Polystyrene Microsphere Targeting to Intestinal M Cells.

Published in:

Journal of Drug Targeting, 2003, v. 11, n. 5, p. 269, doi. 10.1080/10611860310001636502

By:

Jepson, Mark A.;
Simmons, Nicholas L.;
O'Hagan, Derek T.;
Hirst, Barry H.

Publication type:

Article

Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.

Published in:

Science Translational Medicine, 2023, v. 15, n. 695, p. 1, doi. 10.1126/scitranslmed.adg7404

By:

Feng, Yupeng;
Yuan, Meng;
Powers, John M.;
Hu, Mengyun;
Munt, Jennifer E.;
Arunachalam, Prabhu S.;
Leist, Sarah R.;
Bellusci, Lorenza;
Kim, JungHyun;
Sprouse, Kaitlin R.;
Adams, Lily E.;
Sundaramurthy, Sumana;
Zhu, Xueyong;
Shirreff, Lisa M.;
Mallory, Michael L.;
Scobey, Trevor D.;
Moreno, Alberto;
O'Hagan, Derek T.;
Kleanthous, Harry;
Villinger, Francois J.

Publication type:

Article

Novel adjuvant Alum-TLR7 significantly potentiates immune response to glycoconjugate vaccines.

Published in:

Scientific Reports, 2016, p. 29063, doi. 10.1038/srep29063

By:

Buonsanti, Cecilia;
Balocchi, Cristiana;
Harfouche, Carole;
Corrente, Federica;
Galli Stampino, Luisa;
Mancini, Francesca;
Tontini, Marta;
Malyala, Padma;
Bufali, Simone;
Baudner, Barbara;
De Gregorio, Ennio;
Valiante, Nicholas M.;
O'Hagan, Derek T.;
Rappuoli, Rino;
D'Oro, Ugo

Publication type:

Article

MRI/PET multimodal imaging of the innate immune response in skeletal muscle and draining lymph node post vaccination in rats.

Published in:

Frontiers in Immunology, 2023, v. 13, p. 1, doi. 10.3389/fimmu.2022.1081156

By:

Madi, Saaussan;
Fang Xie;
Farhangi, Kamyar;
Chih-Yang Hsu;
Shih-Hsun Cheng;
Aweda, Tolulope;
Radaram, Bhasker;
Slania, Stephanie;
Lambert, Tammy;
Rambo, Mary;
Skedzielewski, Tina;
Cole, Austin;
Sherina, Valeriia;
McKearnan, Shannon;
Tran, Hoang;
Alsaid, Hasan;
Doan, Minh;
Stokes, Alan H.;
O'Hagan, Derek T.;
Maruggi, Giulietta

Publication type:

Article

Combinations of protein polysaccharide conjugate vaccines for intranasal immunization.

Published in:

2002

By:

Ugozzoli, Mildred;
Mariani, Massimo;
Del Giudice, Guiseppe;
Seonawan, Elawati;
O'Hagan, Derek T.;
Del Giudice, Giuseppe;
Soenawan, Elawati

Publication type:

journal article

Potency of a genetically detoxified mucosal adjuvant derived from the heat-labile enterotoxin of Escherichia coli (LTK63) is not adversely affected by the presence of preexisting immunity to the adjuvant.

Published in:

2001

By:

Ugozzoli, Mildred;
Santos, George;
Donnelly, John;
O'Hagan, Derek T.;
Ugozzoli, M;
Santos, G;
Donnelly, J;
O'Hagan, D T

Publication type:

journal article