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Psychosis Genetics: Modeling the Relationship Between Schizophrenia, Bipolar Disorder, and Mixed (or “Schizoaffective”) Psychoses.
Published in:
Schizophrenia Bulletin, 2009, v. 35, n. 3, p. 482, doi. 10.1093/schbul/sbp020
By:
- Craddock, Nick;
- O'Donovan, M. C.;
- Owen, M. J.
Publication type:
Article
Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.
Published in:
Molecular Psychiatry, 2015, v. 20, n. 12, p. 1588, doi. 10.1038/mp.2015.6
By:
- Desikan, R S;
- Schork, A J;
- Wang, Y;
- Witoelar, A;
- Sharma, M;
- McEvoy, L K;
- Holland, D;
- Brewer, J B;
- Chen, C-H;
- Thompson, W K;
- Harold, D;
- Williams, J;
- Owen, M J;
- O'Donovan, M C;
- Pericak-Vance, M A;
- Mayeux, R;
- Haines, J L;
- Farrer, L A;
- Schellenberg, G D;
- Heutink, P
Publication type:
Article
Evaluating historical candidate genes for schizophrenia.
Published in:
Molecular Psychiatry, 2015, v. 20, n. 5, p. 555, doi. 10.1038/mp.2015.16
By:
- Farrell, M S;
- Werge, T;
- Sklar, P;
- Owen, M J;
- Ophoff, R A;
- O'Donovan, M C;
- Corvin, A;
- Cichon, S;
- Sullivan, P F
Publication type:
Article
Schizophrenia genetics: emerging themes for a complex disorder.
Published in:
Molecular Psychiatry, 2015, v. 20, n. 1, p. 72, doi. 10.1038/mp.2014.148
By:
- Kavanagh, D H;
- Tansey, K E;
- O'Donovan, M C;
- Owen, M J
Publication type:
Article
Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.
Published in:
Molecular Psychiatry, 2014, v. 19, n. 9, p. 1017, doi. 10.1038/mp.2013.138
By:
- Ruderfer, D M;
- Fanous, A H;
- Ripke, S;
- McQuillin, A;
- Amdur, R L;
- Gejman, P V;
- O'Donovan, M C;
- Andreassen, O A;
- Djurovic, S;
- Hultman, C M;
- Kelsoe, J R;
- Jamain, S;
- Landén, M;
- Leboyer, M;
- Nimgaonkar, V;
- Nurnberger, J;
- Smoller, J W;
- Craddock, N;
- Corvin, A;
- Sullivan, P F
Publication type:
Article
Response to 'Predicting the diagnosis of autism spectrum disorder using gene pathway analysis'.
Published in:
Molecular Psychiatry, 2014, v. 19, n. 8, p. 860, doi. 10.1038/mp.2013.125
By:
- Robinson, E B;
- Howrigan, D;
- Yang, J;
- Ripke, S;
- Anttila, V;
- Duncan, L E;
- Jostins, L;
- Barrett, J C;
- Medland, S E;
- MacArthur, D G;
- Breen, G;
- O'Donovan, M C;
- Wray, N R;
- Devlin, B;
- Daly, M J;
- Visscher, P M;
- Sullivan, P F;
- Neale, B M
Publication type:
Article
Copy number variation in schizophrenia in Sweden.
Published in:
Molecular Psychiatry, 2014, v. 19, n. 7, p. 762, doi. 10.1038/mp.2014.40
By:
- Szatkiewicz, J P;
- O'Dushlaine, C;
- Chen, G;
- Chambert, K;
- Moran, J L;
- Neale, B M;
- Fromer, M;
- Ruderfer, D;
- Akterin, S;
- Bergen, S E;
- Kähler, A;
- Magnusson, P K E;
- Kim, Y;
- Crowley, J J;
- Rees, E;
- Kirov, G;
- O'Donovan, M C;
- Owen, M J;
- Walters, J;
- Scolnick, E
Publication type:
Article
Functional SNPs are enriched for schizophrenia association signals.
Published in:
Molecular Psychiatry, 2014, v. 19, n. 3, p. 276, doi. 10.1038/mp.2013.33
By:
- Bacanu, S-A;
- Chen, J;
- Sun, J;
- Richardson, K;
- Lai, C-Q;
- Zhao, Z;
- O'Donovan, M C;
- Kendler, K S;
- Chen, X
Publication type:
Article
Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.
Published in:
Molecular Psychiatry, 2013, v. 18, n. 12, p. 1302, doi. 10.1038/mp.2012.142
By:
- Green, E K;
- Hamshere, M;
- Forty, L;
- Gordon-Smith, K;
- Fraser, C;
- Russell, E;
- Grozeva, D;
- Kirov, G;
- Holmans, P;
- Moran, J L;
- Purcell, S;
- Sklar, P;
- Owen, M J;
- O'Donovan, M C;
- Jones, L;
- Jones, I R;
- Craddock, N
Publication type:
Article
Association at SYNE1 in both bipolar disorder and recurrent major depression.
Published in:
Molecular Psychiatry, 2013, v. 18, n. 5, p. 614, doi. 10.1038/mp.2012.48
By:
- Green, E K;
- Grozeva, D;
- Forty, L;
- Gordon-Smith, K;
- Russell, E;
- Farmer, A;
- Hamshere, M;
- Jones, I R;
- Jones, L;
- McGuffin, P;
- Moran, J L;
- Purcell, S;
- Sklar, P;
- Owen, M J;
- O'Donovan, M C;
- Craddock, N
Publication type:
Article
The ENCODE project: implications for psychiatric genetics.
Published in:
Molecular Psychiatry, 2013, v. 18, n. 5, p. 540, doi. 10.1038/mp.2013.13
By:
- Kavanagh, D H;
- Dwyer, S;
- O'Donovan, M C;
- Owen, M J
Publication type:
Article
Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia.
Published in:
Molecular Psychiatry, 2012, v. 17, n. 10, p. 996, doi. 10.1038/mp.2011.117
By:
- Lips, E S;
- Cornelisse, L N;
- Toonen, R F;
- Min, J L;
- Hultman, C M;
- Holmans, P A;
- O'Donovan, M C;
- Purcell, S M;
- Smit, A B;
- Verhage, M;
- Sullivan, P F;
- Visscher, P M;
- Posthuma, D
Publication type:
Article
Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction.
Published in:
Molecular Psychiatry, 2012, v. 17, n. 9, p. 887, doi. 10.1038/mp.2012.37
By:
- Ayalew, M;
- Le-Niculescu, H;
- Levey, D F;
- Jain, N;
- Changala, B;
- Patel, S D;
- Winiger, E;
- Breier, A;
- Shekhar, A;
- Amdur, R;
- Koller, D;
- Nurnberger, J I;
- Corvin, A;
- Geyer, M;
- Tsuang, M T;
- Salomon, D;
- Schork, N J;
- Fanous, A H;
- O'Donovan, M C;
- Niculescu, A B
Publication type:
Article
Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain.
Published in:
Molecular Psychiatry, 2012, v. 17, n. 2, p. 193, doi. 10.1038/mp.2011.11
By:
- Richards, A L;
- Jones, L;
- Moskvina, V;
- Kirov, G;
- Gejman, P V;
- Levinson, D F;
- Sanders, A R;
- Purcell, S;
- Visscher, P M;
- Craddock, N;
- Owen, M J;
- Holmans, P;
- O'Donovan, M C
Publication type:
Article
GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia.
Published in:
Molecular Psychiatry, 2011, v. 16, n. 11, p. 1117, doi. 10.1038/mp.2010.96
By:
- Chen, X;
- Lee, G;
- Maher, B S;
- Fanous, A H;
- Chen, J;
- Zhao, Z;
- Guo, A;
- van den Oord, E;
- Sullivan, P F;
- Shi, J;
- Levinson, D F;
- Gejman, P V;
- Sanders, A;
- Duan, J;
- Owen, M J;
- Craddock, N J;
- O'Donovan, M C;
- Blackman, J;
- Lewis, D;
- Kirov, G K
Publication type:
Article
A family-based study of common polygenic variation and risk of schizophrenia.
Published in:
Molecular Psychiatry, 2011, v. 16, n. 9, p. 887, doi. 10.1038/mp.2011.34
By:
- Ruderfer, D. M.;
- Kirov, G.;
- Chambert, K.;
- Moran, J. L.;
- Owen, M. J.;
- O'Donovan, M. C.;
- Sklar, P.;
- Purcell, S. M.
Publication type:
Article
Investigation of rare non-synonymous variants at ABCA13 in schizophrenia and bipolar disorder.
Published in:
2011
By:
- Dwyer, S.;
- Williams, H.;
- Jones, I.;
- Jones, L.;
- Walters, J.;
- Craddock, N.;
- Owen, M. J.;
- O'Donovan, M. C.
Publication type:
Letter
Independent evidence for the selective influence of GABA<sub>A</sub> receptors on one component of the bipolar disorder phenotype.
Published in:
2011
By:
- Breuer, R.;
- Hamshere, M. L.;
- Strohmaier, J.;
- Mattheisen, M.;
- Degenhardt, F.;
- Meier, S.;
- Paul, T.;
- O'Donovan, M. C.;
- Mühleisen, T. W.;
- Schulze, T. G.;
- Nöthen, M. M.;
- Cichon, S.;
- Craddock, N.;
- Rietschel, M.
Publication type:
Letter
The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia.
Published in:
Molecular Psychiatry, 2010, v. 15, n. 10, p. 1016, doi. 10.1038/mp.2009.49
By:
- Green, E. K.;
- Grozeva, D.;
- Jones, I.;
- Jones, L.;
- Kirov, G.;
- Caesar, S.;
- Gordon-Smith, K.;
- Fraser, C.;
- Forty, L.;
- Russell, E.;
- Hamshere, M. L.;
- Moskvina, V.;
- Nikolov, I.;
- Farmer, A.;
- McGuffin, P.;
- Holmans, P. A.;
- Owen, M. J.;
- O'Donovan, M. C.;
- Craddock, N.
Publication type:
Article
A genome-wide association study in 574 schizophrenia trios using DNA pooling.
Published in:
Molecular Psychiatry, 2009, v. 14, n. 8, p. 796, doi. 10.1038/mp.2008.33
By:
- Kirov, G.;
- Zaharieva, I.;
- Georgieva, L.;
- Moskvina, V.;
- Nikolov, I.;
- Cichon, S.;
- Hillmer, A.;
- Toncheva, D.;
- Owen, M. J.;
- O'Donovan, M. C.
Publication type:
Article
Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms.
Published in:
Molecular Psychiatry, 2009, v. 14, n. 8, p. 786, doi. 10.1038/mp.2009.11
By:
- Holmans, P. A.;
- Riley, B.;
- Pulver, A. E.;
- Owen, M. J.;
- Wildenauer, D. B.;
- Gejman, P. V.;
- Mowry, B. J.;
- Laurent, C.;
- Kendler, K. S.;
- Nestadt, G.;
- Williams, N. M.;
- Schwab, S. G.;
- Sanders, A. R.;
- Nertney, D.;
- Mallet, J.;
- Wormley, B.;
- Lasseter, V. K.;
- O'Donovan, M. C.;
- Duan, J.;
- Albus, M.
Publication type:
Article
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk.
Published in:
Molecular Psychiatry, 2009, v. 14, n. 3, p. 252, doi. 10.1038/mp.2008.133
By:
- Moskvina, V.;
- Craddock, N.;
- Holmans, P.;
- Nikolov, I.;
- Pahwa, J. S.;
- Green, E.;
- Owen, M. J.;
- O'Donovan, M. C.
Publication type:
Article
Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2.
Published in:
Molecular Psychiatry, 2009, v. 14, n. 1, p. 30, doi. 10.1038/mp.2008.108
By:
- O'Donovan, M. C.;
- Norton, N.;
- Williams, H.;
- Peirce, T.;
- Moskvina, V.;
- Nikolov, I.;
- Hamshere, M.;
- Carroll, L.;
- Georgieva, L.;
- Dwyer, S.;
- Holmans, P.;
- Marchini, J. L.;
- Spencer, C. C. A.;
- Howie, B.;
- Leung, H.-T.;
- Giegling, I.;
- Hartmann, A. M.;
- Möller, H.-J.;
- Morris, D. W.;
- Shi, Y.
Publication type:
Article
Genome-wide association studies in psychiatry: lessons from early studies of non-psychiatric and psychiatric phenotypes.
Published in:
Molecular Psychiatry, 2008, v. 13, n. 7, p. 649, doi. 10.1038/mp.2008.45
By:
- Craddock, N.;
- O'Donovan, M. C.;
- Owen, M. J.
Publication type:
Article
Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene.
Published in:
Molecular Psychiatry, 2008, v. 13, n. 2, p. 162, doi. 10.1038/sj.mp.4001991
By:
- Buxbaum, J. D.;
- Georgieva, L.;
- Young, J. J.;
- Plescia, C.;
- Kajiwara, Y.;
- Jiang, Y.;
- Moskvina, V.;
- Norton, N.;
- Peirce, T.;
- Williams, H.;
- Craddock, N. J.;
- Carroll, L.;
- Corfas, G.;
- Davis, K. L.;
- Owen, M. J.;
- Harroch, S.;
- Sakurai, T.;
- O'Donovan, M. C.
Publication type:
Article
Genome-wide association study on bipolar disorder in the Bulgarian population.
Published in:
Genes, Brain & Behavior, 2011, v. 10, n. 7, p. 789, doi. 10.1111/j.1601-183X.2011.00721.x
By:
- Yosifova, A.;
- Mushiroda, T.;
- Kubo, M.;
- Takahashi, A.;
- Kamatani, Y.;
- Kamatani, N.;
- Stoianov, D.;
- Vazharova, R.;
- Karachanak, S.;
- Zaharieva, I.;
- Dimova, I.;
- Hadjidekova, S.;
- Milanova, V.;
- Madjirova, N.;
- Gerdjikov, I.;
- Tolev, T.;
- Poryazova, N.;
- O'Donovan, M. C.;
- Owen, M. J.;
- Kirov, G.
Publication type:
Article
Steroid sulfatase is a potential modifier of cognition in attention deficit hyperactivity disorder.
Published in:
Genes, Brain & Behavior, 2011, v. 10, n. 3, p. 334, doi. 10.1111/j.1601-183X.2010.00672.x
By:
- Stergiakouli, E.;
- Langley, K.;
- Williams, H.;
- Walters, J.;
- Williams, N. M.;
- Suren, S.;
- Giegling, I.;
- Wilkinson, L. S.;
- Owen, M. J.;
- O'Donovan, M. C.;
- Rujescu, D.;
- Thapar, A.;
- Davies, W.
Publication type:
Article
Screening the human protocadherin 8 ( PCDH8) gene in schizophrenia.
Published in:
Genes, Brain & Behavior, 2002, v. 1, n. 3, p. 187, doi. 10.1034/j.1601-183X.2002.10307.x
By:
- Bray, N. J.;
- Kirov, G.;
- Owen, R. J.;
- Jacobsen, N. J.;
- Georgieva, L.;
- Williams, H. J.;
- Norton, N.;
- Spurlock, G.;
- Jones, S.;
- Zammit, S.;
- O'Donovan, M. C.;
- Owen, M. J.
Publication type:
Article
Genetic risk for schizophrenia is associated with altered visually-induced gamma band activity: evidence from a population sample stratified polygenic risk.
Published in:
Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01678-z
By:
- Dimitriadis, S. I.;
- Perry, G.;
- Foley, S. F.;
- Tansey, K. E.;
- Jones, D. K.;
- Holmans, P.;
- Zammit, S.;
- Hall, J.;
- O'Donovan, M. C.;
- Owen, M. J.;
- Singh, K. D.;
- Linden, D. E.
Publication type:
Article
MiR-137-derived polygenic risk: effects on cognitive performance in patients with schizophrenia and controls.
Published in:
Translational Psychiatry, 2017, v. 7, n. 1, p. e1012, doi. 10.1038/tp.2016.286
By:
- Cosgrove, D;
- Harold, D;
- Mothersill, O;
- Anney, R;
- Hill, M J;
- Bray, N J;
- Blokland, G;
- Petryshen, T;
- Richards, A;
- Mantripragada, K;
- Owen, M;
- O'Donovan, M C;
- Gill, M;
- Corvin, A;
- Morris, D W;
- Donohoe, G
Publication type:
Article
Exome arrays capture polygenic rare variant contributions to schizophrenia.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 5, p. 1001, doi. 10.1093/hmg/ddv620
By:
- Richards, A. L.;
- Leonenko, G.;
- Walters, J. T.;
- Kavanagh, D. H.;
- Rees, E. G.;
- Evans, A.;
- Chambert, K. D.;
- Moran, J. L.;
- Goldstein, J.;
- Neale, B. M.;
- McCarroll, S. A.;
- Pocklington, A. J.;
- Holmans, P. A.;
- Owen, M. J.;
- O'Donovan, M. C.
Publication type:
Article
Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia.
Published in:
Molecular Psychiatry, 2006, v. 11, n. 12, p. 1085, doi. 10.1038/sj.mp.4001904
By:
- Harold, D.;
- Paracchini, S.;
- Scerri, T.;
- Dennis, M.;
- Cope, N.;
- Hill, G.;
- Moskvina, V.;
- Walter, J.;
- Richardson, A. J.;
- Owen, M. J.;
- Stein, J. F.;
- Green, E. D.;
- O'Donovan, M. C.;
- Williams, J.;
- Monaco, A. P.
Publication type:
Article
Linkage disequilibrium structure of KIAA0319 and DCDC2, two candidate susceptibility genes for developmental dyslexia.
Published in:
Molecular Psychiatry, 2006, v. 11, n. 12, p. 1061, doi. 10.1038/sj.mp.4001930
By:
- Harold, D.;
- Paracchini, S.;
- Scerri, T.;
- Dennis, M.;
- Cope, N.;
- Hill, G.;
- Moskvina, V.;
- Walter, J.;
- Richardson, A. J.;
- Owen, M. J.;
- Stein, J. F.;
- Green, E. D.;
- O'Donovan, M. C.;
- Williams, J.;
- Monaco, A. P.
Publication type:
Article
Evidence that a DISC1 frame-shift deletion associated with psychosis in a single family may not be a pathogenic mutation.
Published in:
2006
By:
- Green, E. K.;
- Norton, N.;
- Peirce, T.;
- Grozeva, D.;
- Kirov, G.;
- Owen, M. J.;
- O’Donovan, M. C.;
- Craddock, N.
Publication type:
Letter
The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons.
Published in:
Molecular Psychiatry, 2006, v. 11, n. 5, p. 446, doi. 10.1038/sj.mp.4001808
By:
- Craddock, N;
- Owen, M J;
- O'Donovan, M C
Publication type:
Article
Identification of a potential Bipolar risk haplotype in the gene encoding the winged-helix transcription factor RFX4.
Published in:
Molecular Psychiatry, 2005, v. 10, n. 10, p. 920, doi. 10.1038/sj.mp.4001689
By:
- Glaser, B.;
- Kirov, G.;
- Bray, N. J.;
- Green, E.;
- O'Donovan, M. C.;
- Craddock, N.;
- Owen, M. J.
Publication type:
Article
Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD.
Published in:
Molecular Psychiatry, 2005, v. 10, n. 10, p. 939, doi. 10.1038/sj.mp.4001696
By:
- Kent, L.;
- Green, E.;
- Hawi, Z.;
- Kirley, A.;
- Dudbridge, F.;
- Lowe, N.;
- Raybould, R.;
- Langley, K.;
- Bray, N.;
- Fitzgerald, M.;
- Owen, M. J.;
- O'Donovan, M. C.;
- Gill, M.;
- Thapar, A.;
- Craddock, N.
Publication type:
Article
The serotonin-2A receptor gene locus does not contain common polymorphism affecting mRNA levels in adult brain.
Published in:
Molecular Psychiatry, 2004, v. 9, n. 1, p. 109, doi. 10.1038/sj.mp.4001366
By:
- Bray, N. J.;
- Buckland, P. R.;
- Hall, H.;
- Owen, M. J.;
- O'Donovan, M. C.
Publication type:
Article
The molecular genetics of schizophrenia: new findings promise new insights.
Published in:
Molecular Psychiatry, 2004, v. 9, n. 1, p. 14, doi. 10.1038/sj.mp.4001444
By:
- Owen, M. J.;
- Williams, N. M.;
- O'Donovan, M. C.
Publication type:
Article
Association between PRODH and schizophrenia is not confirmed.
Published in:
2003
By:
- Williams, H J;
- Williams, N;
- Spurlock, G;
- Norton, N;
- Ivanov, D;
- McCreadie, R G;
- Preece, A;
- Sharkey, V;
- Jones, S;
- Zammit, S;
- Nikolov, I;
- Kehaiov, I;
- Thapar, A;
- Murphy, K C;
- Kirov, G;
- Owen, M J;
- O'Donovan, M C
Publication type:
Letter
Support for genetic variation in neuregulin 1 and susceptibility to schizophrenia.
Published in:
Molecular Psychiatry, 2003, v. 8, n. 5, p. 485, doi. 10.1038/sj.mp.4001348
By:
- Williams, N M;
- Preece, A;
- Spurlock, G;
- Norton, N;
- Williams, H J;
- Zammit, S;
- O'Donovan, M C;
- Owen, M J
Publication type:
Article
Linkage disequilibrium mapping provides further evidence of a gene for reading disability on chromosome 6p21.3-22.
Published in:
Molecular Psychiatry, 2003, v. 8, n. 2, p. 176, doi. 10.1038/sj.mp.4001216
By:
- Turic, D.;
- Robinson, L.;
- Duke, M.;
- Morris, D. W.;
- Webb, V.;
- Hamshere, M.;
- Milham, C.;
- Hopkin, E.;
- Pound, K.;
- Fernando, S.;
- Grierson, A.;
- Easton, M.;
- Williams, N.;
- Van Den Bree, M.;
- Chowdhury, R.;
- Gruen, J.;
- Stevenson, J.;
- Krawczak, M.;
- Owen, M. J.;
- O'Donovan, M. C.
Publication type:
Article
Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder.
Published in:
Molecular Psychiatry, 2001, v. 6, n. 6, p. 671, doi. 10.1038/sj.mp.4000899
By:
- Kirov, G;
- Lowry, C A;
- Stephens, M;
- Oldfield, S;
- O’Donovan, M C;
- Lightman, S L;
- Owen, M J
Publication type:
Article
Levels of GABAa receptor subunit mRNA in rat brain following flurazepam treatment.
Published in:
1992
By:
- O'Donovan, Michael C.;
- Buckland, Paul R.;
- McGuffin, Peter;
- O'Donovan, M C;
- Buckland, P R;
- McGuffin, P
Publication type:
journal article

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