Found: 4

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  • Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40760-6
    By:
    • Rasool, Reyaz ur;
    • O'Connor, Caitlin M.;
    • Das, Chandan Kanta;
    • Alhusayan, Mohammed;
    • Verma, Brijesh Kumar;
    • Islam, Sehbanul;
    • Frohner, Ingrid E.;
    • Deng, Qu;
    • Mitchell-Velasquez, Erick;
    • Sangodkar, Jaya;
    • Ahmed, Aqila;
    • Linauer, Sarah;
    • Mudrak, Ingrid;
    • Rainey, Jessica;
    • Zawacki, Kaitlin P.;
    • Suhan, Tahra K.;
    • Callahan, Catherine G.;
    • Rebernick, Ryan;
    • Natesan, Ramakrishnan;
    • Siddiqui, Javed
    Publication type:
    Article

  • The SRG rat, a Sprague-Dawley Rag2/Il2rg double-knockout validated for human tumor oncology studies.

    Published in:
    PLoS ONE, 2020, v. 15, n. 10, p. 1, doi. 10.1371/journal.pone.0240169
    By:
    • Noto, Fallon K.;
    • Sangodkar, Jaya;
    • Adedeji, Bisoye Towobola;
    • Moody, Sam;
    • McClain, Christopher B.;
    • Tong, Ming;
    • Ostertag, Eric;
    • Crawford, Jack;
    • Gao, Xiaohua;
    • Hurst, Lauren;
    • O'Connor, Caitlin M.;
    • Hanson, Erika N.;
    • Izadmehr, Sudeh;
    • Tohmé, Rita;
    • Narla, Jyothsna;
    • LeSueur, Kristin;
    • Bhattacharya, Kajari;
    • Rupani, Amit;
    • Tayeh, Marwan K.;
    • Innis, Jeffrey W.
    Publication type:
    Article

  • Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth.

    Published in:
    2017
    By:
    • Sangodkar, Jaya;
    • Perl, Abbey;
    • Tohme, Rita;
    • Kiselar, Janna;
    • Kastrinsky, David B.;
    • Zaware, Nilesh;
    • Izadmehr, Sudeh;
    • Mazhar, Sahar;
    • Wiredja, Danica D.;
    • O'Connor, Caitlin M.;
    • Hoon, Divya;
    • Dhawan, Neil S.;
    • Schlatzer, Daniela;
    • Shen Yao;
    • Leonard, Daniel;
    • Borczuk, Alain C.;
    • Gokulrangan, Giridharan;
    • Lifu Wang;
    • Svenson, Elena;
    • Farrington, Caroline C.
    Publication type:
    journal article

  • PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells.

    Published in:
    Science Translational Medicine, 2018, v. 10, n. 450, p. 1, doi. 10.1126/scitranslmed.aaq1093
    By:
    • Kauko, Otto;
    • O'Connor, Caitlin M.;
    • Kulesskiy, Evgeny;
    • Sangodkar, Jaya;
    • Aakula, Anna;
    • Izadmehr, Sudeh;
    • Yetukuri, Laxman;
    • Yadav, Bhagwan;
    • Padzik, Artur;
    • Laajala, Teemu Daniel;
    • Haapaniemi, Pekka;
    • Momeny, Majid;
    • Varila, Taru;
    • Ohlmeyer, Michael;
    • Aittokallio, Tero;
    • Wennerberg, Krister;
    • Narla, Goutham;
    • Westermarck, Jukka
    Publication type:
    Article