Works by O'Connell, Jeffrey R.

Results: 60
    1

    General Kernel Machine Methods for Multi‐Omics Integration and Genome‐Wide Association Testing With Related Individuals.

    Published in:
    Genetic Epidemiology, 2025, v. 49, n. 1, p. 1, doi. 10.1002/gepi.22610
    By:
    • Little, Amarise;
    • Zhao, Ni;
    • Mikhaylova, Anna;
    • Zhang, Angela;
    • Ling, Wodan;
    • Thibord, Florian;
    • Johnson, Andrew D.;
    • Raffield, Laura M.;
    • Curran, Joanne E.;
    • Blangero, John;
    • O'Connell, Jeffrey R.;
    • Xu, Huichun;
    • Rotter, Jerome I.;
    • Rich, Stephen S.;
    • Rice, Kenneth M.;
    • Chen, Ming‐Huei;
    • Reiner, Alexander;
    • Kooperberg, Charles;
    • Vu, Thao;
    • Hou, Lifang
    Publication type:
    Article
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    A fully adjusted two‐stage procedure for rank‐normalization in genetic association studies.

    Published in:
    Genetic Epidemiology, 2019, v. 43, n. 3, p. 263, doi. 10.1002/gepi.22188
    By:
    • Sofer, Tamar;
    • Zheng, Xiuwen;
    • Gogarten, Stephanie M.;
    • Laurie, Cecelia A.;
    • Grinde, Kelsey;
    • Shaffer, John R.;
    • Shungin, Dmitry;
    • O'Connell, Jeffrey R.;
    • Durazo‐Arvizo, Ramon A.;
    • Raffield, Laura;
    • Lange, Leslie;
    • Musani, Solomon;
    • Vasan, Ramachandran S.;
    • Cupples, L. Adrienne;
    • Reiner, Alexander P.;
    • Laurie, Cathy C.;
    • Rice, Kenneth M.
    Publication type:
    Article
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    Analysis of complex oligogenic disease.

    Published in:
    Genetic Epidemiology, 1997, v. 14, n. 6, p. 861, doi. 10.1002/(SICI)1098-2272(1997)14:6<861::AID-GEPI50>3.0.CO;2-K
    By:
    • O'Connell, Jeffrey R.;
    • Davis, Sean;
    • Weeks, Daniel E.
    Publication type:
    Article
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    Exome-chip meta-analysis identifies association between variation in ANKRD26 and platelet aggregation.

    Published in:
    Platelets, 2019, v. 30, n. 2, p. 164, doi. 10.1080/09537104.2017.1384538
    By:
    • Chen, Ming-Huei;
    • Eicher, John D.;
    • Huffman, Jennifer E.;
    • Johnson, Andrew D.;
    • Yanek, Lisa R.;
    • Becker, Diane M.;
    • Backman, Joshua D.;
    • Yerges-Armstrong, Laura M.;
    • Shuldiner, Alan R.;
    • O'Connell, Jeffrey R.;
    • Lewis, Joshua P.;
    • Ben-Shlomo, Yoav;
    • Beswick, Andrew D.;
    • Mathias, Rasika A.;
    • Becker, Lewis C.;
    • Faraday, Nauder
    Publication type:
    Article
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    Toxoplasma gondii Serointensity and Seropositivity: Heritability and Household-Related Associations in the Old Order Amish.

    Published in:
    International Journal of Environmental Research & Public Health, 2019, v. 16, n. 19, p. 3732, doi. 10.3390/ijerph16193732
    By:
    • Duffy, Allyson R.;
    • O'Connell, Jeffrey R.;
    • Pavlovich, Mary;
    • Ryan, Kathleen A.;
    • Lowry, Christopher A.;
    • Daue, Melanie;
    • Raheja, Uttam K.;
    • Brenner, Lisa A.;
    • Markon, André O.;
    • Punzalan, Cecile M.;
    • Dagdag, Aline;
    • Hill, Dolores E.;
    • Pollin, Toni I.;
    • Seyfang, Andreas;
    • Groer, Maureen W.;
    • Mitchell, Braxton D.;
    • Postolache, Teodor T.
    Publication type:
    Article
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    Variant-specific inflation factors for assessing population stratification at the phenotypic variance level.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23655-2
    By:
    • Sofer, Tamar;
    • Zheng, Xiuwen;
    • Laurie, Cecelia A.;
    • Gogarten, Stephanie M.;
    • Brody, Jennifer A.;
    • Conomos, Matthew P.;
    • Bis, Joshua C.;
    • Thornton, Timothy A.;
    • Szpiro, Adam;
    • O'Connell, Jeffrey R.;
    • Lange, Ethan M.;
    • Gao, Yan;
    • Cupples, L. Adrienne;
    • Psaty, Bruce M.;
    • NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium;
    • Abe, Namiko;
    • Abecasis, Gonçalo;
    • Aguet, Francois;
    • Albert, Christine;
    • Almasy, Laura
    Publication type:
    Article
    13

    Genomic inflation factors under polygenic inheritance.

    Published in:
    European Journal of Human Genetics, 2011, v. 19, n. 7, p. 807, doi. 10.1038/ejhg.2011.39
    By:
    • Yang, Jian;
    • Weedon, Michael N.;
    • Purcell, Shaun;
    • Lettre, Guillaume;
    • Estrada, Karol;
    • Willer, Cristen J.;
    • Smith, Albert V.;
    • Ingelsson, Erik;
    • O'Connell, Jeffrey R.;
    • Mangino, Massimo;
    • Mägi, Reedik;
    • Madden, Pamela A.;
    • Heath, Andrew C.;
    • Nyholt, Dale R.;
    • Martin, Nicholas G.;
    • Montgomery, Grant W.;
    • Frayling, Timothy M.;
    • Hirschhorn, Joel N.;
    • McCarthy, Mark I.;
    • Goddard, Michael E.
    Publication type:
    Article
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    New loci associated with kidney function and chronic kidney disease.

    Published in:
    Nature Genetics, 2010, v. 42, n. 5, p. 376, doi. 10.1038/ng.568
    By:
    • Köttgen, Anna;
    • Pattaro, Cristian;
    • Böger, Carsten A.;
    • Fuchsberger, Christian;
    • Olden, Matthias;
    • Glazer, Nicole L.;
    • Parsa, Afshin;
    • Xiaoyi Gao;
    • Qiong Yang;
    • Smith, Albert V.;
    • O'Connell, Jeffrey R.;
    • Man Li;
    • Schmidt, Helena;
    • Tanaka, Toshiko;
    • Isaacs, Aaron;
    • Ketkar, Shamika;
    • Shih-Jen Hwang;
    • Johnson, Andrew D.;
    • Dehghan, Abbas;
    • Teumer, Alexander
    Publication type:
    Article
    17

    A Central Role for <i>GRB10</i> in Regulation of Islet Function in Man.

    Published in:
    PLoS Genetics, 2014, v. 10, n. 4, p. 1, doi. 10.1371/journal.pgen.1004235
    By:
    • Prokopenko, Inga;
    • Poon, Wenny;
    • Mägi, Reedik;
    • Prasad B, Rashmi;
    • Salehi, S. Albert;
    • Almgren, Peter;
    • Osmark, Peter;
    • Bouatia-Naji, Nabila;
    • Wierup, Nils;
    • Fall, Tove;
    • Stančáková, Alena;
    • Barker, Adam;
    • Lagou, Vasiliki;
    • Osmond, Clive;
    • Xie, Weijia;
    • Lahti, Jari;
    • Jackson, Anne U.;
    • Cheng, Yu-Ching;
    • Liu, Jie;
    • O'Connell, Jeffrey R.
    Publication type:
    Article
    18

    A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function.

    Published in:
    PLoS Genetics, 2013, v. 9, n. 2, p. 1, doi. 10.1371/journal.pgen.1003266
    By:
    • Porcu, Eleonora;
    • Medici, Marco;
    • Pistis, Giorgio;
    • Volpato, Claudia B.;
    • Wilson, Scott G.;
    • Cappola, Anne R.;
    • Bos, Steffan D.;
    • Deelen, Joris;
    • den Heijer, Martin;
    • Freathy, Rachel M.;
    • Lahti, Jari;
    • Chunyu Liu;
    • Lopez, Lorna M.;
    • Nolte, Ilja M.;
    • O'Connell, Jeffrey R.;
    • Tanaka, Toshiko;
    • Trompet, Stella;
    • Arnold, Alice;
    • Bandinelli, Stefania;
    • Beekman, Marian
    Publication type:
    Article
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    Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction.

    Published in:
    Human Molecular Genetics, 2021, v. 30, n. 15, p. 1443, doi. 10.1093/hmg/ddab096
    By:
    • Palmer, Nicholette D;
    • Kahali, Bratati;
    • Kuppa, Annapurna;
    • Chen, Yanhua;
    • Du, Xiaomeng;
    • Feitosa, Mary F;
    • Bielak, Lawrence F;
    • O'Connell, Jeffrey R;
    • Musani, Solomon K;
    • Guo, Xiuqing;
    • Smith, Albert V;
    • Ryan, Kathleen A;
    • Eirksdottir, Gudny;
    • Allison, Matthew A;
    • Bowden, Donald W;
    • Budoff, Matthew J;
    • Carr, J Jeffrey;
    • Chen, Yii-Der I;
    • Taylor, Kent D;
    • Correa, Adolfo
    Publication type:
    Article
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    Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy.

    Published in:
    JAMA: Journal of the American Medical Association, 2009, v. 302, n. 8, p. 849, doi. 10.1001/jama.2009.1232
    By:
    • Shuldiner, Alan R.;
    • O'Connell, Jeffrey R.;
    • Bliden, Kevin P.;
    • Gandhi, Amish;
    • Ryan, Kathleen;
    • Horenstein, Richard B.;
    • Damcott, Coleen M.;
    • Pakyz, Ruth;
    • Tantry, Udaya S.;
    • Gibson, Quince;
    • Pollin, Toni I.;
    • Post, Wendy;
    • Parsa, Afshin;
    • Mitchell, Braxton D.;
    • Faraday, Nauder;
    • Herzog, William;
    • Gurbel, Paul A.
    Publication type:
    Article
    24

    Genomic evaluations with many more genotypes.

    Published in:
    Genetics Selection Evolution, 2011, v. 43, n. 3, p. 1, doi. 10.1186/1297-9686-43-10
    By:
    • VanRaden, Paul M.;
    • O'Connell, Jeffrey R.;
    • Wiggans, George R.;
    • Weigel, Kent A.
    Publication type:
    Article
    25

    Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program.

    Published in:
    Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03702-4
    By:
    • DiCorpo, Daniel;
    • Gaynor, Sheila M.;
    • Russell, Emily M.;
    • Westerman, Kenneth E.;
    • Raffield, Laura M.;
    • Majarian, Timothy D.;
    • Wu, Peitao;
    • Sarnowski, Chloé;
    • Highland, Heather M.;
    • Jackson, Anne;
    • Hasbani, Natalie R.;
    • de Vries, Paul S.;
    • Brody, Jennifer A.;
    • Hidalgo, Bertha;
    • Guo, Xiuqing;
    • Perry, James A.;
    • O'Connell, Jeffrey R.;
    • Lent, Samantha;
    • Montasser, May E.;
    • Cade, Brian E.
    Publication type:
    Article
    26

    An Amish founder population reveals rare-population genetic determinants of the human lipidome.

    Published in:
    Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03291-2
    By:
    • Montasser, May E.;
    • Aslibekyan, Stella;
    • Srinivasasainagendra, Vinodh;
    • Tiwari, Hemant K.;
    • Patki, Amit;
    • Bagheri, Minoo;
    • Kind, Tobias;
    • Barupal, Dinesh Kumar;
    • Fan, Sili;
    • Perry, James;
    • Ryan, Kathleen A.;
    • Shuldiner, Alan R.;
    • Arnett, Donna K.;
    • Beitelshees, Amber L.;
    • Irvin, Marguerite Ryan;
    • O'Connell, Jeffrey R.
    Publication type:
    Article
    27

    Phosphodiesterase 4D polymorphisms and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study.

    Published in:
    Human Molecular Genetics, 2006, v. 15, n. 16, p. 2468, doi. 10.1093/hmg/ddl169
    By:
    • Song, Qing;
    • Cole, John W.;
    • O'Connell, Jeffrey R.;
    • Stine, Oscar C.;
    • Gallagher, Margaret;
    • Giles, Wayne H.;
    • Mitchell, Braxton D.;
    • Wozniak, Marcella A.;
    • Stern, Barney J.;
    • Sorkin, John D.;
    • McArdle, Patrick F.;
    • Naj, Adam C.;
    • Xu, Qin;
    • Gibbons, Gary H.;
    • Kittner, Steven J.
    Publication type:
    Article
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    A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates.

    Published in:
    Nature Communications, 2013, v. 4, n. 12, p. 2872, doi. 10.1038/ncomms3872
    By:
    • Tachmazidou, Ioanna;
    • Dedoussis, George;
    • Southam, Lorraine;
    • Farmaki, Aliki-Eleni;
    • Ritchie, Graham R. S.;
    • Xifara, Dionysia K.;
    • Matchan, Angela;
    • Hatzikotoulas, Konstantinos;
    • Rayner, Nigel W.;
    • Chen, Yuan;
    • Pollin, Toni I.;
    • O'Connell, Jeffrey R.;
    • Yerges-Armstrong, Laura M.;
    • Kiagiadaki, Chrysoula;
    • Panoutsopoulou, Kalliope;
    • Schwartzentruber, Jeremy;
    • Moutsianas, Loukas;
    • Tsafantakis, Emmanouil;
    • Tyler-Smith, Chris;
    • McVean, Gil
    Publication type:
    Article
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    Deep-coverage whole genome sequences and blood lipids among 16,324 individuals.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05747-8
    By:
    • Natarajan, Pradeep;
    • Peloso, Gina M.;
    • Zekavat, Seyedeh Maryam;
    • Montasser, May;
    • Ganna, Andrea;
    • Chaffin, Mark;
    • Khera, Amit V.;
    • Zhou, Wei;
    • Bloom, Jonathan M.;
    • Engreitz, Jesse M.;
    • Ernst, Jason;
    • O’Connell, Jeffrey R.;
    • Ruotsalainen, Sanni E.;
    • Alver, Maris;
    • Manichaikul, Ani;
    • Johnson, W. Craig;
    • Perry, James A.;
    • Poterba, Timothy;
    • Seed, Cotton;
    • Surakka, Ida L.
    Publication type:
    Article
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    Variation Within the Gene Encoding the Upstream Stimulatory Factor 1 Does Not Influence Susceptibility to Type 2 Diabetes in Samples From Populations With Replicated Evidence of Linkage to Chromosome 1q.

    Published in:
    Diabetes, 2006, v. 55, n. 9, p. 2541, doi. 10.2337/db06-0088
    By:
    • Zeggini, Eleftheria;
    • Damcott, Coleen M.;
    • Hanson, Robert L.;
    • Karim, Mohammad A.;
    • Rayner, N. William;
    • Groves, Christopher J.;
    • Baier, Leslie J.;
    • Hale, Terri C.;
    • Hattersley, Andrew T.;
    • Hitman, Graham A.;
    • Hunt, Sarah E.;
    • Knowler, William C.;
    • Mitchell, Braxton D.;
    • Ng, Maggie C. Y.;
    • O'Connell, Jeffrey R.;
    • Pollin, Toni I.;
    • Vaxillaire, Martine;
    • Walker, Mark;
    • Xiaoqin Wang;
    • Whittaker, Pamela
    Publication type:
    Article
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