Works by Nyman, Jeffry

Results: 58

Changes in the Fracture Resistance of Bone with the Progression of Type 2 Diabetes in the ZDSD Rat.

Published in:

2016

By:

Creecy, Amy;
Uppuganti, Sasidhar;
Merkel, Alyssa;
O'Neal, Dianne;
Makowski, Alexander;
Granke, Mathilde;
Voziyan, Paul;
Nyman, Jeffry;
Merkel, Alyssa R;
Makowski, Alexander J;
Nyman, Jeffry S

Publication type:

journal article

Measuring differences in compositional properties of bone tissue by confocal Raman spectroscopy.

Published in:

2011

By:

Nyman, Jeffry;
Makowski, Alexander;
Patil, Chetan;
Masui, T.;
O'Quinn, Elizabeth;
Bi, Xiaohong;
Guelcher, Scott;
Nicollela, Daniel;
Mahadevan-Jansen, Anita;
Nyman, Jeffry S;
Makowski, Alexander J;
Patil, Chetan A;
Masui, T Philip;
O'Quinn, Elizabeth C;
Guelcher, Scott A;
Nicollela, Daniel P

Publication type:

journal article

Differences in sensitivity to microstructure between cyclic- and impact-based microindentation of human cortical bone.

Published in:

Journal of Orthopaedic Research, 2017, v. 35, n. 7, p. 1442, doi. 10.1002/jor.23392

By:

Uppuganti, Sasidhar;
Granke, Mathilde;
Manhard, Mary Kate;
Does, Mark D.;
Perrien, Daniel S.;
Lee, Donald H.;
Nyman, Jeffry S.

Publication type:

Article

Local application of a proteasome inhibitor enhances fracture healing in rats.

Published in:

Journal of Orthopaedic Research, 2015, v. 33, n. 8, p. 1197, doi. 10.1002/jor.22849

By:

Yoshii, Toshitaka;
Nyman, Jeffry S.;
Yuasa, Masato;
Esparza, Javier M.;
Okawa, Atsushi;
Gutierrez, Gloria E.

Publication type:

Article

Fracture healing in protease-activated receptor-2 deficient mice.

Published in:

Journal of Orthopaedic Research, 2012, v. 30, n. 8, p. 1271, doi. 10.1002/jor.22071

By:

O'Neill, Kevin R.;
Stutz, Christopher M.;
Mignemi, Nicholas A.;
Cole, Heather;
Murry, Matthew R.;
Nyman, Jeffry S.;
Hamm, Heidi;
Schoenecker, Jonathan G.

Publication type:

Article

T1 relaxation of bound and pore water in cortical bone.

Published in:

NMR in Biomedicine, 2023, v. 36, n. 5, p. 1, doi. 10.1002/nbm.4878

By:

Ketsiri, Thammathida;
Uppuganti, Sasidhar;
Harkins, Kevin D.;
Gochberg, Daniel F.;
Nyman, Jeffry S.;
Does, Mark D.

Publication type:

Article

Pivotal roles of biglycan and decorin in regulating bone mass, water retention, and bone toughness.

Published in:

Bone Research, 2025, v. 13, n. 1, p. 1, doi. 10.1038/s41413-024-00380-2

By:

Hua, Rui;
Han, Yan;
Ni, Qingwen;
Fajardo, Roberto J.;
Iozzo, Renato V.;
Ahmed, Rafay;
Nyman, Jeffry S.;
Wang, Xiaodu;
Jiang, Jean X.

Publication type:

Article

Loss of Insulin Receptor in Osteoprogenitor Cells Impairs Structural Strength of Bone.

Published in:

Journal of Diabetes Research, 2014, p. 1, doi. 10.1155/2014/703589

By:

Thrailkill, Kathryn;
Bunn, R. Clay;
Lumpkin Jr., Charles;
Wahl, Elizabeth;
Cockrell, Gael;
Morris, Lindsey;
Kahn, C. Ronald;
Fowlkes, John;
Nyman, Jeffry S.

Publication type:

Article

N-acetylcysteine (NAC), an anti-oxidant, does not improve bone mechanical properties in a rat model of progressive chronic kidney disease-mineral bone disorder.

Published in:

PLoS ONE, 2020, v. 15, n. 3, p. 1, doi. 10.1371/journal.pone.0230379

By:

Allen, Matthew R.;
Wallace, Joseph;
McNerney, Erin;
Nyman, Jeffry;
Avin, Keith;
Chen, Neal;
Moe, Sharon

Publication type:

Article

Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 8, p. 3117, doi. 10.1172/JCI80313

By:

Masato Yuasa;
Mignemi, Nicholas A.;
Nyman, Jeffry S.;
Duvall, Craig L.;
Schwartz, Herbert S.;
Atsushi Okawa;
Toshitaka Yoshii;
Bhattacharjee, Gourab;
Chenguang Zhao;
Bible, Jesse E.;
Obremskey, William T.;
Flick, Matthew J.;
Degen, Jay L.;
Barnett, Joey V.;
Cates, Justin M. M.;
Schoenecker, Jonathan G.

Publication type:

Article

Pharmacologic Inhibition of Myostatin With a Myostatin Antibody Improves the Skeletal Muscle and Bone Phenotype of Male Insulin‐Deficient Diabetic Mice.

Published in:

JBMR Plus, 2023, v. 7, n. 11, p. 1, doi. 10.1002/jbm4.10833

By:

Bunn, R Clay;
Adatorwovor, Reuben;
Smith, Rebecca R;
Ray, Philip D;
Fields, Sarah E;
Keeble, Alexander R;
Fry, Christopher S;
Uppuganti, Sasidhar;
Nyman, Jeffry S;
Fowlkes, John L;
Kalaitzoglou, Evangelia

Publication type:

Article

Inhibition of TGF‐β Increases Bone Volume and Strength in a Mouse Model of Osteogenesis Imperfecta.

Published in:

JBMR Plus, 2021, v. 5, n. 9, p. 1, doi. 10.1002/jbm4.10530

By:

Greene, Benjamin;
Russo, Ryan J;
Dwyer, Shannon;
Malley, Katie;
Roberts, Errin;
Serrielo, Joseph;
Piepenhagen, Peter;
Cummings, Sheila;
Ryan, Susan;
Zarazinski, Christine;
Uppuganti, Sasidhar;
Bukanov, Nikolai;
Nyman, Jeffry S;
Cox, Megan K;
Liu, Shiguang;
Ibraghimov‐Beskrovnaya, Oxana;
Sabbagh, Yves

Publication type:

Article

Manipulating the Amount and Structure of the Organic Matrix Affects the Water Compartments of Human Cortical Bone.

Published in:

JBMR Plus, 2019, v. 3, n. 6, p. N.PAG, doi. 10.1002/jbm4.10135

By:

Nyman, Jeffry S;
Uppuganti, Sasidhar;
Unal, Mustafa;
Leverant, Calen J;
Adabala, Saahit;
Granke, Mathilde;
Voziyan, Paul;
Does, Mark D

Publication type:

Article

Finite element analysis of bone mechanical properties using MRI-derived bound and pore water concentration maps.

Published in:

Computer Methods in Biomechanics & Biomedical Engineering, 2023, v. 26, n. 8, p. 905, doi. 10.1080/10255842.2022.2098016

By:

Ketsiri, Thammathida;
Uppuganti, Sasidhar;
Harkins, Kevin D.;
Gochberg, Daniel F.;
Nyman, Jeffry S.;
Does, Mark D.

Publication type:

Article

Fibrin Accumulation Secondary to Loss of Plasmin-Mediated Fibrinolysis Drives Inflammatory Osteoporosis in Mice.

Published in:

Arthritis & Rheumatology, 2014, v. 66, n. 8, p. 2222, doi. 10.1002/art.38639

By:

Cole, Heather A.;
Ohba, Tetsuro;
Nyman, Jeffry S.;
Hirotaka, Haro;
Cates, Justin M. M.;
Flick, Matthew J.;
Degen, Jay L.;
Schoenecker, Jonathan G.

Publication type:

Article

Transdermal Lovastatin Enhances Fracture Repair in Rats.

Published in:

Journal of Bone & Mineral Research, 2008, v. 23, n. 11, p. 1722, doi. 10.1359/jbmr.080603

By:

Gloria E. Gutierrez;
James R. Edwards;
Ian R. Garrett;
Jeffry S. Nyman;
McCluskey, Brandon;
Rossini, Gianni;
Flores, Alda;
Dana B. Neidre;
Mundy, Gregory R

Publication type:

Article

Autologous chondrocyte grafting promotes bone formation in the posterolateral spine.

Published in:

JOR Spine, 2018, v. 1, n. 1, p. 1, doi. 10.1002/jsp2.1001

By:

Sielatycki, J. Alex;
Saito, Masanori;
Yuasa, Masato;
Moore-Lotridge, Stephanie N.;
Uppuganti, Sasidhar;
Colazo, Juan M.;
Hysong, Alexander A.;
Robinette, J. Patton;
Okawa, Atsushi;
Yoshii, Toshitaka;
Schwartz, Herbert S.;
Nyman, Jeffry S.;
Schoenecker, Jonathan G.

Publication type:

Article

Age-related factors affecting the postyield energy dissipation of human cortical bone.

Published in:

Journal of Orthopaedic Research, 2007, v. 25, n. 5, p. 646, doi. 10.1002/jor.20337

By:

Nyman, Jeffry S.;
Roy, Anuradha;
Tyler, Jerrod H.;
Acuna, Rae L.;
Gayle, Heather J.;
Wang, Xiaodu

Publication type:

Article

Long stemmed total knee arthroplasty with interlocking screws: a computational bone adaptation study

Published in:

Journal of Orthopaedic Research, 2004, v. 22, n. 1, p. 51, doi. 10.1016/S0736-0266(03)00159-1

By:

Nyman, Jeffry S.;
Hazelwood, Scott J.;
Rodrigo, Juan J.;
Martin, R. Bruce;
Yeh, Oscar C.

Publication type:

Article

The use of nanoindentation for characterizing the properties of mineralized hard tissues: State‐of‐the art review.

Published in:

Journal of Biomedical Materials Research, Part B: Applied Biomaterials, 2008, v. 87B, n. 1, p. 286, doi. 10.1002/jbm.b.31092

By:

Lewis, Gladius;
Nyman, Jeffry S.

Publication type:

Article

Fast bound and pore water mapping of cortical bone with arbitrary slice oriented two‐dimensional ultra‐short echo time.

Published in:

Magnetic Resonance in Medicine, 2023, v. 89, n. 2, p. 767, doi. 10.1002/mrm.29484

By:

Harkins, Kevin D.;
Ketsiri, Thammathida;
Nyman, Jeffry S.;
Does, Mark D.

Publication type:

Article

Bone Fragility in High Fat Diet-induced Obesity is Partially Independent of Type 2 Diabetes in Mice.

Published in:

Calcified Tissue International, 2024, v. 115, n. 3, p. 298, doi. 10.1007/s00223-024-01252-x

By:

Uppuganti, Sasidhar;
Creecy, Amy;
Fernandes, Daniel;
Garrett, Kate;
Donovan, Kara;
Ahmed, Rafay;
Voziyan, Paul;
Rendina-Ruedy, Elizabeth;
Nyman, Jeffry S.

Publication type:

Article

The Role of Water Compartments in the Material Properties of Cortical Bone.

Published in:

Calcified Tissue International, 2015, v. 97, n. 3, p. 292, doi. 10.1007/s00223-015-9977-5

By:

Granke, Mathilde;
Does, Mark;
Nyman, Jeffry

Publication type:

Article

Unexpected timely fracture union in matrix metalloproteinase 9 deficient mice.

Published in:

PLoS ONE, 2018, v. 13, n. 6, p. 1, doi. 10.1371/journal.pone.0198088

By:

Yuasa, Masato;
Saito, Masanori;
Molina, Cesar;
Moore-Lotridge, Stephanie N.;
Benvenuti, Michael A.;
Mignemi, Nicholas A.;
Okawa, Atsushi;
Yoshii, Toshitaka;
Schwartz, Herbert S.;
Nyman, Jeffry S.;
Schoenecker, Jonathan G.

Publication type:

Article

Identifying Bone Matrix Impairments in a Mouse Model of Neurofibromatosis Type 1 (NF1) by Clinically Translatable Techniques.

Published in:

Journal of Bone & Mineral Research, 2022, v. 37, n. 8, p. 1603, doi. 10.1002/jbmr.4633

By:

Ahmed, Rafay;
Uppuganti, Sasidhar;
Derasari, Shrey;
Meyer, Joshua;
Pennings, Jacquelyn S.;
Elefteriou, Florent;
Nyman, Jeffry S.

Publication type:

Article

Identifying Novel Clinical Surrogates to Assess Human Bone Fracture Toughness.

Published in:

Journal of Bone & Mineral Research, 2015, v. 30, n. 7, p. 1290, doi. 10.1002/jbmr.2452

By:

Granke, Mathilde;
Makowski, Alexander J;
Uppuganti, Sasidhar;
Does, Mark D;
Nyman, Jeffry S

Publication type:

Article

Combined MEK Inhibition and BMP2 Treatment Promotes Osteoblast Differentiation and Bone Healing in Nf1Osx-/- Mice.

Published in:

Journal of Bone & Mineral Research, 2015, v. 30, n. 6, p. 1118, doi. 10.1002/jbmr.2500

By:

de la Croix Ndong, Jean;
Stevens, David M;
Vignaux, Guillaume;
Uppuganti, Sasidhar;
Perrien, Daniel S;
Yang, Xiangli;
Nyman, Jeffry S;
Harth, Eva;
Elefteriou, Florent

Publication type:

Article

Combined MEK Inhibition and BMP2 Treatment Promotes Osteoblast Differentiation and Bone Healing in Nf1Osx−/− Mice.

Published in:

Journal of Bone & Mineral Research, 2015, v. 30, n. 1, p. 55, doi. 10.1002/jbmr.2316

By:

de la Croix Ndong, Jean;
Stevens, David M;
Vignaux, Guillaume;
Uppuganti, Sasidhar;
Perrien, Daniel S;
Yang, Xiangli;
Nyman, Jeffry S;
Harth, Eva;
Elefteriou, Florent

Publication type:

Article

Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling.

Published in:

Journal of Bone & Mineral Research, 2013, v. 28, n. 4, p. 960, doi. 10.1002/jbmr.1824

By:

Edwards, James R;
Perrien, Daniel S;
Fleming, Nicole;
Nyman, Jeffry S;
Ono, Koichiro;
Connelly, Linda;
Moore, Megan M;
Lwin, Seint T;
Yull, Fiona E;
Mundy, Gregory R;
Elefteriou, Florent

Publication type:

Article

Differential effects between the loss of MMP-2 and MMP-9 on structural and tissue-level properties of bone.

Published in:

Journal of Bone & Mineral Research, 2011, v. 26, n. 6, p. 1252, doi. 10.1002/jbmr.326

By:

Nyman, Jeffry S.;
Lynch, Conor C.;
Perrien, Daniel S.;
Thiolloy, Sophie;
O'Quinn, Elizabeth C.;
Patil, Chetan A.;
Bi, Xiaohong;
Pharr, George M.;
Mahadevan-Jansen, Anita;
Mundy, Gregory R.

Publication type:

Article

Inhibition of TGF-β Signaling by 1D11 Antibody Treatment Increases Bone Mass and Quality In Vivo.

Published in:

Journal of Bone & Mineral Research, 2010, v. 25, n. 11, p. 2419, doi. 10.1002/jbmr.139

By:

Edwards, James R.;
Nyman, Jeffry S.;
Lwin, Seint T.;
Moore, Megan M.;
Esparza, Javier;
O'Quinn, Elizabeth C.;
Hart, Andrew J.;
Biswas, Swati;
Patil, Chetan A.;
Lonning, Scott;
Mahadevan-Jansen, Anita;
Mundy, Gregory R.

Publication type:

Article

Local Low-Dose Lovastatin Delivery Improves the Bone-Healing Defect Caused by Loss of Function in Osteoblasts.

Published in:

Journal of Bone & Mineral Research, 2010, v. 25, n. 7, p. 1658, doi. 10.1002/jbmr.42

By:

Weixi Wang;
Nyman, Jeffry S.;
Moss, Heather E.;
Gutierrez, Gloria;
Mundy, Gregory R.;
Xiangli Yang;
Elefteriou, Florent

Publication type:

Article

Type 1 Diabetes in Young Rats Leads to Progressive Trabecular Bone Loss, Cessation of Cortical Bone Growth, and Diminished Whole Bone Strength and Fatigue Life.

Published in:

Journal of Bone & Mineral Research, 2009, v. 24, n. 9, p. 1618, doi. 10.1359/JBMR.090316

By:

Silva, Matthew J.;
Brodt, Michael D.;
Lynch, Michelle A.;
McKenzie, Jennifer A.;
Tanouye, Kristi M.;
Nyman, Jeffry S.;
Xiaodu Wang

Publication type:

Article

Corrigendum: Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 414, doi. 10.1038/nm0415-414c

By:

de la Croix Ndong, Jean;
Makowski, Alexander J;
Uppuganti, Sasidhar;
Vignaux, Guillaume;
Ono, Koichiro;
Perrien, Daniel S;
Joubert, Simon;
Baglio, Serena R;
Granchi, Donatella;
Stevenson, David A;
Rios, Jonathan J;
Nyman, Jeffry S;
Elefteriou, Florent

Publication type:

Article

Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.

Published in:

Nature Medicine, 2014, v. 20, n. 8, p. 904, doi. 10.1038/nm.3583

By:

de la Croix Ndong, Jean;
Makowski, Alexander J;
Uppuganti, Sasidhar;
Vignaux, Guillaume;
Ono, Koichiro;
Perrien, Daniel S;
Joubert, Simon;
Baglio, Serena R;
Granchi, Donatella;
Stevenson, David A;
Rios, Jonathan J;
Nyman, Jeffry S;
Elefteriou, Florent

Publication type:

Article

Polarization in Raman spectroscopy helps explain bone brittleness in genetic mouse models.

Published in:

Journal of Biomedical Optics, 2014, v. 19, n. 11, p. 1, doi. 10.1117/1.JBO.19.11.117008

By:

Makowski, Alexander J.;
Pence, Isaac J.;
Uppuganti, Sasidhar;
Zein-Sabatto, Ahbid;
Huszagh, Meredith C.;
Mahadevan-Jansen, Anita;
Nyman, Jeffry S.

Publication type:

Article

Development of Raman spectral markers to assess metastatic bone in breast cancer.

Published in:

Journal of Biomedical Optics, 2014, v. 19, n. 11, p. 1, doi. 10.1117/1.JBO.19.11.111606

By:

Hao Ding;
Nyman, Jeffry S.;
Sterling, Julie A.;
Perrien, Daniel S.;
Mahadevan-Jansen, Anita;
Xiaohong Bi

Publication type:

Article

Polarization control of Raman spectroscopy optimizes the assessment of bone tissue.

Published in:

Journal of Biomedical Optics, 2013, v. 18, n. 5, p. 1, doi. 10.1117/1.JBO.18.5.055005

By:

Makowski, Alexander J.;
Patil, Chetan A.;
Mahadevan-Jansen, Anita;
Nyman, Jeffry S.

Publication type:

Article

Integrated system for combined Raman spectroscopy–spectral domain optical coherence tomography.

Published in:

Journal of Biomedical Optics, 2011, v. 16, n. 1, p. 011007, doi. 10.1117/1.3520132

By:

Chetan A. Patil;
Jeroen Kalkman;
Dirk J. Faber;
Jeffry S. Nyman;
Ton G. van Leeuwen;
Anita Mahadevan-Jansen

Publication type:

Article

Biomechanical Evaluation of Physeal-Sparing Fixation Methods in Tibial Eminence Fractures.

Published in:

American Journal of Sports Medicine, 2013, v. 41, n. 7, p. 1586, doi. 10.1177/0363546513488505

By:

Anderson, Christian N.;
Nyman, Jeffry S.;
McCullough, Kirk A.;
Song, Yanna;
Uppuganti, Sasidhar;
O’Neill, Kevin R.;
Anderson, Allen F.;
Dunn, Warren R.

Publication type:

Article

Assessing glycation‐mediated changes in human cortical bone with Raman spectroscopy.

Published in:

Journal of Biophotonics, 2018, v. 11, n. 8, p. 1, doi. 10.1002/jbio.201700352

By:

Unal, Mustafa;
Uppuganti, Sasidhar;
Leverant, Calen J.;
Creecy, Amy;
Granke, Mathilde;
Voziyan, Paul;
Nyman, Jeffry S.

Publication type:

Article

Cortical Bone Mechanical Properties Are Altered in an Animal Model of Progressive Chronic Kidney Disease.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099262

By:

Newman, Christopher L.;
Moe, Sharon M.;
Chen, Neal X.;
Hammond, Max A.;
Wallace, Joseph M.;
Nyman, Jeffry S.;
Allen, Matthew R.

Publication type:

Article

Micro-Computed Tomography Derived Anisotropy Detects Tumor Provoked Deviations in Bone in an Orthotopic Osteosarcoma Murine Model.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0097381

By:

Cole, Heather A.;
Ohba, Tetsuro;
Ichikawa, Jiro;
Nyman, Jeffry S.;
Cates, Justin M. M.;
Haro, Hirotaka;
Schwartz, Herbert S.;
Schoenecker, Jonathan G.

Publication type:

Article

Anti-Transforming Growth Factor β Antibody Treatment Rescues Bone Loss and Prevents Breast Cancer Metastasis to Bone.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027090

By:

Biswas, Swati;
Nyman, Jeffry S.;
Alvarez, JoAnn;
Chakrabarti, Anwesa;
Ayres, Austin;
Sterling, Julie;
Edwards, James;
Rana, Tapasi;
Johnson, Rachelle;
Perrien, Daniel S.;
Lonning, Scott;
Shyr, Yu;
Matrisian, Lynn M.;
Mundy, Gregory R.

Publication type:

Article

Non-invasive Predictors of Human Cortical Bone Mechanical Properties: T2-Discriminated 1H NMR Compared with High Resolution X-ray.

Published in:

PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016359

By:

Horch, R. Adam;
Gochberg, Daniel F.;
Nyman, Jeffry S.;
Does, Mark D.

Publication type:

Article

In Vivo Assessment of Bone Quality Without X-rays.

Published in:

Current Osteoporosis Reports, 2024, v. 22, n. 1, p. 56, doi. 10.1007/s11914-023-00856-w

By:

Surowiec, Rachel K.;
Does, Mark D.;
Nyman, Jeffry S.

Publication type:

Article

The Role of Matrix Composition in the Mechanical Behavior of Bone.

Published in:

Current Osteoporosis Reports, 2018, v. 16, n. 3, p. 205, doi. 10.1007/s11914-018-0433-0

By:

Unal, Mustafa;
Creecy, Amy;
Nyman, Jeffry S.

Publication type:

Article

Tissue-Level Mechanical Properties of Bone Contributing to Fracture Risk.

Published in:

Current Osteoporosis Reports, 2016, v. 14, n. 4, p. 138, doi. 10.1007/s11914-016-0314-3

By:

Nyman, Jeffry;
Granke, Mathilde;
Singleton, Robert;
Pharr, George

Publication type:

Article

The Contribution of the Extracellular Matrix to the Fracture Resistance of Bone.

Published in:

Current Osteoporosis Reports, 2012, v. 10, n. 2, p. 169, doi. 10.1007/s11914-012-0101-8

By:

Nyman, Jeffry;
Makowski, Alexander

Publication type:

Article

30-Second bound and pore water concentration mapping of cortical bone using 2D UTE with optimized half-pulses.

Published in:

Magnetic Resonance in Medicine, 2017, v. 77, n. 3, p. 945, doi. 10.1002/mrm.26605

By:

Manhard, Mary Kate;
Harkins, Kevin D.;
Gochberg, Daniel F.;
Nyman, Jeffry S.;
Does, Mark D.

Publication type:

Article