Works matching AU Nusse, Roel

Results: 46

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15.

Published in:

Nature, 1984, v. 307, n. 5947, p. 131, doi. 10.1038/307131a0

By:

Nusse, Roel;
van Ooyen, Albert;
Cox, David;
Fung, Yuen Kai T.;
Varmus, Harold

Publication type:

Article

Wnt1 is epistatic to Id2 in inducing mammary hyperplasia, ductal side-branching, and tumors in the mouse.

Published in:

BMC Cancer, 2004, v. 4, p. 91, doi. 10.1186/1471-2407-4-91

By:

Marino, Susan;
Romelfanger, Claire;
Yokota, Yoshifumi;
Nusse, Roel

Publication type:

Article

Pathogenesis of Listeria-Infected Drosophila wntD Mutants Is Associated with Elevated Levels of the Novel Immunity Gene edin.

Published in:

PLoS Pathogens, 2008, v. 4, n. 7, p. 1, doi. 10.1371/journal.ppat.1000111

By:

Gordon, Michael D.;
Ayres, Janelle S.;
Schneider, David S.;
Nusse, Roel

Publication type:

Article

Self-renewing diploid Axin2<sup>+</sup> cells fuel homeostatic renewal of the liver.

Published in:

Nature, 2015, v. 524, n. 7564, p. 180, doi. 10.1038/nature14863

By:

Wang, Bruce;
Zhao, Ludan;
Fish, Matt;
Logan, Catriona Y.;
Nusse, Roel

Publication type:

Article

Perspectives on the role of Wnt biology in cancer.

Published in:

Science Signaling, 2019, v. 12, n. 589, p. 1, doi. 10.1126/scisignal.aay4494

By:

Mirabelli, Christopher K.;
Nusse, Roel;
Tuveson, David A.;
Williams, Bart O.

Publication type:

Article

A Suppressor/Enhancer Screen in Drosophila Reveals a Role for Wnt-Mediated Lipid Metabolism in Primordial Germ Cell Migration.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0026993

By:

McElwain, Mark A.;
Ko, Dennis C.;
Gordon, Michael D.;
Fyrst, Henrik;
Saba, Julie D.;
Nusse, Roel

Publication type:

Article

Lentiviral Vectors to Probe and Manipulate the Wnt Signaling Pathway.

Published in:

PLoS ONE, 2010, v. 5, n. 2, p. 1, doi. 10.1371/journal.pone.0009370

By:

Fuerer, Christophe;
Nusse, Roel

Publication type:

Article

Liposomal Packaging Generates Wnt Protein with In Vivo Biological Activity.

Published in:

PLoS ONE, 2008, v. 3, n. 8, p. 1, doi. 10.1371/journal.pone.0002930

By:

Morrell, Nathan T.;
Leucht, Philipp;
Zhao, Ludan;
Jae-Beom Kim;
ten Berge, Derk;
Ponnusamy, Karthik;
Carre, A. Lyonel;
Dudek, Henryk;
Zachlederova, Marie;
McElhaney, Michael;
Brunton, Shirley;
Gunzner, Janet;
Callow, Marinella;
Polakis, Paul;
Costa, Mike;
Zhang, Xiaoyan M.;
Helms, Jill A.;
Nusse, Roel

Publication type:

Article

Alternative Wnt Signaling Is Initiated by Distinct Receptors.

Published in:

Science Signaling, 2008, v. 1, n. 35, p. 1, doi. 10.1126/scisignal.135re9

By:

van Amerongen, Renée;
Mikels, Amanda;
Nusse, Roel

Publication type:

Article

A critical role for endocytosis in Wnt signaling.

Published in:

BMC Cell Biology, 2006, v. 7, p. 28, doi. 10.1186/1471-2121-7-28

By:

Blitzer, Jeremy T.;
Nusse, Roel

Publication type:

Article

Genetic Evidence That Drosophila frizzled Controls Planar Cell Polarity and Armadillo Signaling by a Common Mechanism.

Published in:

Genetics, 2005, v. 171, n. 4, p. 1643, doi. 10.1534/genetics.105.045245

By:

Povelones, Michael;
Howes, Rob;
Fish, Matt;
Nusse, Roel

Publication type:

Article

Developmental Roles of the Mi-2/NURD-Associated Protein p66 in Drosophila.

Published in:

Genetics, 2005, v. 169, n. 4, p. 2087, doi. 10.1534/genetics.104.034595

By:

Kon, Charlene;
Cadigan, Kenneth M.;
da Silva, Sofia Lopes;
Nusse, Roel;
Lopez, A. J.

Publication type:

Article

Construction of Transgenic Drosophila by Using the Site-Specific Integrase From Phage ΦC31.

Published in:

Genetics, 2004, v. 166, n. 4, p. 1775, doi. 10.1534/genetics.166.4.1775

By:

Groth, Amy C.;
Fish, Matthew;
Nusse, Roel;
Calos, Michele P.

Publication type:

Article

A Mutational Analysis of dishevelled in Drosophila Defines Novel Domains in the Dishevelled Protein as Well as Novel Suppressing Alleles of axin.

Published in:

Genetics, 2002, v. 161, n. 2, p. 747, doi. 10.1093/genetics/161.2.747

By:

Penton, Andrea;
Wodarz, Andreas;
Nusse, Roel

Publication type:

Article

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination.

Published in:

Nature Neuroscience, 2011, v. 14, n. 8, p. 1009, doi. 10.1038/nn.2855

By:

Fancy, Stephen P. J.;
Harrington, Emily P.;
Yuen, Tracy J.;
Silbereis, John C.;
Chao Zhao;
Baranzini, Sergio E.;
Bruce, Charlotte C.;
Otero, Jose J.;
Huang, Eric J.;
Nusse, Roel;
Franklin, Robin J. M.;
Rowitch, David H.

Publication type:

Article

A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23.

Published in:

Human Molecular Genetics, 1997, v. 6, n. 3, p. 465, doi. 10.1093/hmg/6.3.465

By:

Yu-Ker Wang;
Samos, Cindy Harryman;
Peoples, Risa;
Pérez-Jurado, Luis A.;
Nusse, Roel;
Francke, Uta

Publication type:

Article

In vivo lineage tracing reveals Axin2-expressing, long-lived cortical thymic epithelial progenitors in the postnatal thymus.

Published in:

PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0184582

By:

Tan, Si Hui;
Nusse, Roel

Publication type:

Article

Purified Wnt5a Protein Activates or Inhibits β-Catenin-TCF Signaling Depending on Receptor Context.

Published in:

PLoS Biology, 2006, v. 4, n. 4, p. e115, doi. 10.1371/journal.pbio.0040115

By:

Mikels, Amanda J.;
Nusse, Roel

Publication type:

Article

Patching up Hedgehog.

Published in:

Nature, 1996, v. 384, n. 6605, p. 119, doi. 10.1038/384119a0

By:

Nusse, Roel

Publication type:

Article

Wnt signalling in development and disease. Max Delbrück Center for Molecular Medicine meeting on Wnt Signaling in Development and Disease.

Published in:

EMBO Reports, 2008, v. 9, n. 2, p. 134, doi. 10.1038/sj.embor.7401159

By:

Fuerer, Christophe;
Nusse, Roel;
ten Berge, Derk

Publication type:

Article

Bone Regeneration Is Regulated by Wnt Signaling.

Published in:

Journal of Bone & Mineral Research, 2007, v. 22, n. 12, p. 1913, doi. 10.1359/JBMR.070802

By:

Jae-Beom Kim;
Leucht, Philipp;
Lam, Kentson;
Luppen, Cynthia;
Ten Berge, Derk;
Nusse, Roel;
Helms, Jill A.

Publication type:

Article

LRP5 and Wnt Signaling: A Union Made for Bone.

Published in:

Journal of Bone & Mineral Research, 2004, v. 19, n. 11, p. 1749, doi. 10.1359/JBMR.040816

By:

Johnson, Mark L;
Harnish, Kimberley;
Nusse, Roel;
Van Hul, Wim

Publication type:

Article

Casein kinase 2 associates with and phosphorylates Dishevelled.

Published in:

EMBO Journal, 1997, v. 16, n. 11, p. 3089, doi. 10.1093/emboj/16.11.3089

By:

Willert, Karl;
Brink, Marcel;
Wodarz, Andreas;
Varmus, Harold;
Nusse, Roel

Publication type:

Article

A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53802-4

By:

Wu, Peng V.;
Fish, Matt;
Hazard, Florette K.;
Zhu, Chunfang;
Vennam, Sujay;
Walton, Hannah;
Wagh, Dhananjay;
Coller, John;
Przybyl, Joanna;
Morri, Maurizio;
Neff, Norma;
West, Robert B.;
Nusse, Roel

Publication type:

Article

A role for Wnt signalling in self-renewal of haematopoietic stem cells.

Published in:

Nature, 2003, v. 423, n. 6938, p. 409, doi. 10.1038/nature01593

By:

Reya, Tannishtha;
Duncan, Andrew W.;
Ailles, Laurie;
Domen, Jos;
Scherer, David C.;
Willert, Karl;
Hintz, Lindsay;
Nusse, Roel;
Weissman, Irving L.

Publication type:

Article

Wnt proteins are lipid-modified and can act as stem cell growth factors.

Published in:

Nature, 2003, v. 423, n. 6938, p. 448, doi. 10.1038/nature01611

By:

Willert, Karl;
Brown, Jeffrey D.;
Danenberg, Esther;
Duncan, Andrew W.;
Weissman, Irving L.;
Reya, Tannishtha;
Yates, John R.;
Nusse, Roel

Publication type:

Article

The status of Wnt signalling regulates neural and epidermal fates in the chick embryo.

Published in:

Nature, 2001, v. 411, n. 6835, p. 325, doi. 10.1038/35077115

By:

Wilson, Sara I.;
Rydstrom, Anna;
Trimborn, Tolleiv;
Willert, Karl;
Nusse, Roel;
Jessell, Thomas M.;
Edlund, Thomas

Publication type:

Article

Making head or tail of Dickkopf.

Published in:

Nature, 2001, v. 411, n. 6835, p. 255, doi. 10.1038/35077199

By:

Nusse, Roel

Publication type:

Article

A new secreted protein that binds to Wnt proteins and inhibits their activities.

Published in:

Nature, 1999, v. 398, n. 6726, p. 431, doi. 10.1038/18899

By:

Hsieh, Jen-Chih;
Kodjabachian, Laurent;
Rebbert, Martha L.;
Rattner, Amir;
Smallwood, Philip M.;
Samos, Cynthia Harryman;
Nusse, Roel;
Dawid, Igor B.;
Nathans, Jeremy

Publication type:

Article

Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.82311

By:

Sarkar, Abby;
Yinhua Jin;
DeFelice, Brian C.;
Logan, Catriona Y.;
Yan Yang;
Anbarchian, Teni;
Peng Wu;
Morri, Maurizio;
Neff, Norma F.;
Huy Nguyen;
Rulifson, Eric;
Fish, Matthew;
Kaye, Avi Gurion;
Jaimes, Azalia M. Martínez;
Nusse, Roel

Publication type:

Article

Telomerase modulates Wnt signalling by association with target gene chromatin.

Published in:

Nature, 2009, v. 460, n. 7251, p. 66, doi. 10.1038/nature08137

By:

Jae-Il Park;
Venteicher, Andrew S.;
Ji Yeon Hong;
Jinkuk Choi;
Sohee Jun;
Shkreli, Marina;
Chang, Woody;
Zhaojing Meng;
Cheung, Peggie;
Hong Ji;
McLaughlin, Margaret;
Veenstra, Timothy D.;
Nusse, Roel;
McCrea, Pierre D.;
Artandi, Steven E.

Publication type:

Article

Cell biology: Relays at the membrane.

Published in:

Nature, 2005, v. 438, n. 7069, p. 747, doi. 10.1038/438747a

By:

Nusse, Roel

Publication type:

Article

WntD is a feedback inhibitor of Dorsal/NF-κB in Drosophila development and immunity.

Published in:

Nature, 2005, v. 437, n. 7059, p. 746, doi. 10.1038/nature04073

By:

Gordon, Michael D.;
Dionne, Marc S.;
Schneider, David S.;
Nusse, Roel

Publication type:

Article

A study on the interactions between heparan sulfate proteoglycans and Wnt proteins.

Published in:

Developmental Dynamics, 2010, v. 239, n. 1, p. 184, doi. 10.1002/dvdy.22067

By:

Fuerer, Christophe;
Habib, Shukry J.;
Nusse, Roel

Publication type:

Article

Differential inhibition of Wnt‐3a by Sfrp‐1, Sfrp‐2, and Sfrp‐3.

Published in:

Developmental Dynamics, 2006, v. 235, n. 3, p. 681

By:

Lisa M. Galli;
Tiffany Barnes;
Tina Cheng;
Lisa Acosta;
Adolph Anglade;
Karl Willert;
Roel Nusse;
Laura W. Burrus

Publication type:

Article

Wnt Proteins Promote Bone Regeneration.

Published in:

Science Translational Medicine, 2010, v. 2, n. 29, p. 1, doi. 10.1126/scitranslmed.3000231

By:

Minear, Steven;
Leucht, Philipp;
Jie Jiang;
Bo Liu;
Arial Zeng;
Fuerer, Christophe;
Nusse, Roel;
Helms, Jill A.

Publication type:

Article

Wnt/β-Catenin-Responsive Cells in Prostatic Development and Regeneration.

Published in:

Stem Cells, 2015, v. 33, n. 11, p. 3356, doi. 10.1002/stem.2096

By:

Lee, Suk Hyung;
Johnson, Daniel T.;
Luong, Richard;
Yu, Eun Jeong;
Cunha, Gerald R.;
Nusse, Roel;
Sun, Zijie

Publication type:

Article

ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour.

Published in:

Journal of Pathology, 2012, v. 227, n. 2, p. 223, doi. 10.1002/path.3986

By:

Edris, Badreddin;
Espinosa, Iñigo;
Mühlenberg, Thomas;
Mikels, Amanda;
Lee, Cheng-Han;
Steigen, Sonja E;
Zhu, Shirley;
Montgomery, Kelli D;
Lazar, Alexander JF;
Lev, Dina;
Fletcher, Jonathan A;
Beck, Andrew H;
West, Robert B;
Nusse, Roel;
van de Rijn, Matt

Publication type:

Article

Cell signalling: Disarming Wnt.

Published in:

Nature, 2015, v. 519, n. 7542, p. 163, doi. 10.1038/nature14208

By:

Nusse, Roel

Publication type:

Article

Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.59142

By:

Russell, John P.;
Xinhong Lim;
Santambrogio, Alice;
Yianni, Val;
Kemkem, Yasmine;
Wang, Bruce;
Fish, Matthew;
Haston, Scott;
Grabek, Anaëlle;
Hallang, Shirleen;
Lodge, Emily J.;
Patist, Amanda L.;
Schedl, Andreas;
Mollard, Patrice;
Nusse, Roel;
Andoniadou, Cynthia L.

Publication type:

Article

Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells.

Published in:

Nature Cell Biology, 2011, v. 13, n. 9, p. 1070, doi. 10.1038/ncb2314

By:

Berge, Derk ten;
Kurek, Dorota;
Blauwkamp, Tim;
Koole, Wouter;
Maas, Alex;
Eroglu, Elif;
Siu, Ronald K.;
Nusse, Roel

Publication type:

Article

Wnt signalling sees spots.

Published in:

Nature Cell Biology, 2002, v. 4, n. 11, p. E249, doi. 10.1038/ncb1102-e249

By:

Povelones, Michael;
Nusse, Roel

Publication type:

Article

Three decades of Wnts: a personal perspective on how a scientific field developed.

Published in:

EMBO Journal, 2012, v. 31, n. 12, p. 2670, doi. 10.1038/emboj.2012.146

By:

Nusse, Roel;
Varmus, Harold

Publication type:

Article

The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling.

Published in:

EMBO Journal, 2005, v. 24, n. 19, p. 3493, doi. 10.1038/sj.emboj.7600817

By:

Povelones, Michael;
Nusse, Roel

Publication type:

Article

Wnt signaling and stem cell control.

Published in:

Cell Research, 2008, v. 18, n. 5, p. 523, doi. 10.1038/cr.2008.47

By:

Nusse, Roel

Publication type:

Article

A transcriptional response to Wnt protein in human embryonic carcinoma cells.

Published in:

BMC Developmental Biology, 2002, v. 2, p. 8, doi. 10.1186/1471-213X-2-8

By:

Willert, Jennifer;
Epping, Mirjam;
Pollack, Jonathan R.;
Brown, Patrick O.;
Nusse, Roel

Publication type:

Article