Works by Nuara, Stephen G.

Results: 17

5-HT2A blockade for dyskinesia and psychosis in Parkinson's disease: is there a limit to the efficacy of this approach? A study in the MPTP-lesioned marmoset and a literature mini-review.

Published in:

Experimental Brain Research, 2019, v. 237, n. 2, p. 435, doi. 10.1007/s00221-018-5434-9

By:

Kwan, Cynthia;
Frouni, Imane;
Bédard, Dominique;
Nuara, Stephen G.;
Gourdon, Jim C.;
Hamadjida, Adjia;
Huot, Philippe

Publication type:

Article

Effect of the mGlu2 positive allosteric modulator CBiPES on dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset.

Published in:

Journal of Neural Transmission, 2021, v. 128, n. 1, p. 73, doi. 10.1007/s00702-020-02287-8

By:

Frouni, Imane;
Kwan, Cynthia;
Nuara, Stephen G.;
Belliveau, Sébastien;
Kang, Woojin;
Hamadjida, Adjia;
Bédard, Dominique;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Combined mGlu2 orthosteric stimulation and positive allosteric modulation alleviates l-DOPA-induced psychosis-like behaviours and dyskinesia in the parkinsonian marmoset.

Published in:

Journal of Neural Transmission, 2020, v. 127, n. 7, p. 1023, doi. 10.1007/s00702-020-02185-z

By:

Nuara, Stephen G.;
Hamadjida, Adjia;
Kwan, Cynthia;
Bédard, Dominique;
Frouni, Imane;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

The mGlu2/3 antagonist LY-341,495 reverses the anti-dyskinetic and anti-psychotic effects of the mGlu2 activators LY-487,379 and LY-354,740 in the MPTP-lesioned marmoset.

Published in:

Journal of Neural Transmission, 2020, v. 127, n. 7, p. 1013, doi. 10.1007/s00702-020-02196-w

By:

Nuara, Stephen G.;
Hamadjida, Adjia;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Trazodone alleviates both dyskinesia and psychosis in the parkinsonian marmoset model of Parkinson’s disease.

Published in:

Journal of Neural Transmission, 2018, v. 125, n. 9, p. 1355, doi. 10.1007/s00702-017-1830-8

By:

Hamadjida, Adjia;
Nuara, Stephen G.;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Effect of the mGlu4 positive allosteric modulator ADX-88178 on parkinsonism, psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset.

Published in:

Psychopharmacology, 2023, v. 240, n. 10, p. 2093, doi. 10.1007/s00213-023-06428-1

By:

Frouni, Imane;
Kwan, Cynthia;
Bédard, Dominique;
Kang, Woojin;
Hamadjida, Adjia;
Nuara, Stephen G.;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Effect of mGluR2 and mGluR2/3 activators on parkinsonism in the MPTP-lesioned non-human primate.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, v. 397, n. 11, p. 9135, doi. 10.1007/s00210-024-03216-2

By:

Frouni, Imane;
Kwan, Cynthia;
Bédard, Dominique;
Hamadjida, Adjia;
Kang, Woojin;
Belliveau, Sébastien;
Nuara, Stephen G.;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Positive allosteric mGluR2 modulation with BINA alleviates dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, v. 397, n. 11, p. 8917, doi. 10.1007/s00210-024-03215-3

By:

Kang, Woojin;
Frouni, Imane;
Bédard, Dominique;
Kwan, Cynthia;
Hamadjida, Adjia;
Nuara, Stephen G.;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

The mGluR2/3 orthosteric agonist LY-404,039 reduces dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2023, v. 396, n. 10, p. 2347, doi. 10.1007/s00210-023-02587-2

By:

Kang, Woojin;
Nuara, Stephen G.;
Bédard, Dominique;
Frouni, Imane;
Kwan, Cynthia;
Hamadjida, Adjia;
Gourdon, Jim C.;
Gaudette, Fleur;
Beaudry, Francis;
Huot, Philippe

Publication type:

Article

Distribution of [11C]-JNJ-42491293 in the marmoset brain: a positron emission tomography study.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2023, v. 396, n. 9, p. 2095, doi. 10.1007/s00210-023-02458-w

By:

Kang, Min Su;
Hamadjida, Adjia;
Bédard, Dominique;
Nuara, Stephen G.;
Gourdon, Jim C.;
Frey, Stephen;
Aliaga, Arturo;
Ross, Karen;
Hopewell, Robert;
Bdair, Hussein;
Mathieu, Axel;
Tardif, Christine Lucas;
Soucy, Jean-Paul;
Massarweh, Gassan;
Rosa-Neto, Pedro;
Huot, Philippe

Publication type:

Article

Additive effects of mGluR2 positive allosteric modulation, mGluR2 orthosteric stimulation and 5-HT2AR antagonism on dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2021, v. 394, n. 12, p. 2381, doi. 10.1007/s00210-021-02162-7

By:

Nuara, Stephen G;
Gourdon, Jim C;
Maddaford, Shawn;
Huot, Philippe

Publication type:

Article

Further characterisation of psychosis-like behaviours induced by L-DOPA in the MPTP-lesioned marmoset.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2021, v. 394, n. 8, p. 1685, doi. 10.1007/s00210-021-02090-6

By:

Kwan, Cynthia;
Nuara, Stephen G.;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Monoamine oxidase A inhibition as monotherapy reverses parkinsonism in the MPTP-lesioned marmoset.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2020, v. 393, n. 11, p. 2139, doi. 10.1007/s00210-020-01927-w

By:

Hamadjida, Adjia;
Nuara, Stephen G.;
Frouni, Imane;
Kwan, Cynthia;
Bédard, Dominique;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Monoamine oxidase A inhibition with moclobemide enhances the anti-parkinsonian effect of L-DOPA in the MPTP-lesioned marmoset.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2020, v. 393, n. 11, p. 2157, doi. 10.1007/s00210-020-01933-y

By:

Hamadjida, Adjia;
Nuara, Stephen G.;
Kwan, Cynthia;
Frouni, Imane;
Bédard, Dominique;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Nefazodone reduces dyskinesia, but not psychosis-like behaviours, in the parkinsonian marmoset.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2018, v. 391, n. 12, p. 1339, doi. 10.1007/s00210-018-1549-6

By:

Hamadjida, Adjia;
Nuara, Stephen G.;
Bédard, Dominique;
Frouni, Imane;
Kwan, Cynthia;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Effect of the mGlu2 positive allosteric modulator biphenyl‐indanone A as a monotherapy and as adjunct to a low dose of L‐DOPA in the MPTP‐lesioned marmoset.

Published in:

European Journal of Neuroscience, 2024, v. 60, n. 9, p. 6175, doi. 10.1111/ejn.16454

By:

Kang, Woojin;
Frouni, Imane;
Kwan, Cynthia;
Bédard, Dominique;
Nuara, Stephen G.;
Hamadjida, Adjia;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

The 5‐HT2A/2C inverse agonist nelotanserin alleviates L‐DOPA‐induced dyskinesia in the MPTP‐lesioned marmoset.

Published in:

European Journal of Neuroscience, 2024, v. 59, n. 6, p. 1169, doi. 10.1111/ejn.16104

By:

Kwan, Cynthia;
Frouni, Imane;
Bédard, Dominique;
Hamadjida, Adjia;
Nuara, Stephen G.;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Works by Nuara, Stephen G.

5-HT<sub>2A</sub> blockade for dyskinesia and psychosis in Parkinson's disease: is there a limit to the efficacy of this approach? A study in the MPTP-lesioned marmoset and a literature mini-review.

Effect of the mGlu2 positive allosteric modulator CBiPES on dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset.

Combined mGlu2 orthosteric stimulation and positive allosteric modulation alleviates l-DOPA-induced psychosis-like behaviours and dyskinesia in the parkinsonian marmoset.

The mGlu2/3 antagonist LY-341,495 reverses the anti-dyskinetic and anti-psychotic effects of the mGlu2 activators LY-487,379 and LY-354,740 in the MPTP-lesioned marmoset.

Trazodone alleviates both dyskinesia and psychosis in the parkinsonian marmoset model of Parkinson’s disease.

Effect of the mGlu<sub>4</sub> positive allosteric modulator ADX-88178 on parkinsonism, psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset.

Effect of mGluR<sub>2</sub> and mGluR<sub>2/3</sub> activators on parkinsonism in the MPTP-lesioned non-human primate.

Positive allosteric mGluR<sub>2</sub> modulation with BINA alleviates dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset.

The mGluR<sub>2/3</sub> orthosteric agonist LY-404,039 reduces dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset.

Distribution of [<sup>11</sup>C]-JNJ-42491293 in the marmoset brain: a positron emission tomography study.

Additive effects of mGluR<sub>2</sub> positive allosteric modulation, mGluR<sub>2</sub> orthosteric stimulation and 5-HT<sub>2A</sub>R antagonism on dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset.

Further characterisation of psychosis-like behaviours induced by L-DOPA in the MPTP-lesioned marmoset.

Monoamine oxidase A inhibition as monotherapy reverses parkinsonism in the MPTP-lesioned marmoset.

Monoamine oxidase A inhibition with moclobemide enhances the anti-parkinsonian effect of L-DOPA in the MPTP-lesioned marmoset.

Nefazodone reduces dyskinesia, but not psychosis-like behaviours, in the parkinsonian marmoset.

Effect of the mGlu<sub>2</sub> positive allosteric modulator biphenyl‐indanone A as a monotherapy and as adjunct to a low dose of L‐DOPA in the MPTP‐lesioned marmoset.

The 5‐HT<sub>2A/2C</sub> inverse agonist nelotanserin alleviates L‐DOPA‐induced dyskinesia in the MPTP‐lesioned marmoset.