Works by Norton, Luke

Results: 40

Plasma insulin is required for the increase in plasma angiopoietin‐like protein 8 in response to nutrient ingestion.
Published in:
Diabetes/Metabolism Research & Reviews, 2023, v. 39, n. 6, p. 1, doi. 10.1002/dmrr.3643
By:
- Abu‐Farha, Mohamed;
- Alatrach, Mariam;
- Abubaker, Jehad;
- Al‐Khairi, Irina;
- Cherian, Preethi;
- Agyin, Krisitn;
- Abdelgani, Siham;
- Norton, Luke;
- Adams, John;
- Al‐Saeed, Dalal;
- Al‐Ozairi, Ebaa;
- DeFronzo, Ralph A.;
- Al‐Mulla, Fahd;
- Abdul‐Ghani, Muhammad
Publication type:
Article
The Insulin-Sensitizer Pioglitazone Remodels Adipose Tissue Phospholipids in Humans.
Published in:
Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.784391
By:
- Palavicini, Juan P.;
- Chavez-Velazquez, Alberto;
- Fourcaudot, Marcel;
- Tripathy, Devjit;
- Pan, Meixia;
- Norton, Luke;
- DeFronzo, Ralph A.;
- Shannon, Christopher E.
Publication type:
Article
Efficacy and Safety of SGLT2 Inhibitors in the Treatment of Type 2 Diabetes Mellitus.
Published in:
Current Diabetes Reports, 2012, v. 12, n. 3, p. 230, doi. 10.1007/s11892-012-0275-6
By:
- Abdul-Ghani, Muhammad;
- Norton, Luke;
- DeFronzo, Ralph
Publication type:
Article
FGF21 Is an Insulin-Dependent Postprandial Hormone in Adult Humans.
Published in:
2017
By:
- Samms, Ricardo J;
- Lewis, Jo E;
- Norton, Luke;
- Stephens, Francis B;
- Gaffney, Christopher J;
- Butterfield, Tony;
- Smith, Dennis;
- Cheng, Christine;
- Perfield, James W 2nd;
- Adams, Andrew C;
- Ebling, Francis J P;
- Tsintzas, Kostas;
- Smith, Dennis P;
- Cheng, Christine C
Publication type:
journal article
Dapagliflozin Enhances Fat Oxidation and Ketone Production in Patients With Type 2 Diabetes.
Published in:
2016
By:
- Daniele, Giuseppe;
- Juan Xiong;
- Solis-Herrera, Carolina;
- Merovci, Aurora;
- Eldor, Roy;
- Tripathy, Devjit;
- DeFronzo, Ralph A.;
- Norton, Luke;
- Abdul-Ghani, Muhammad;
- Xiong, Juan
Publication type:
journal article
The relationship between {beta}-cell function and glycated hemoglobin: results from the veterans administration genetic epidemiology study.
Published in:
2011
By:
- Kanat M;
- Winnier D;
- Norton L;
- Arar N;
- Jenkinson C;
- Defronzo RA;
- Abdul-Ghani MA;
- Kanat, Mustafa;
- Winnier, Diedre;
- Norton, Luke;
- Arar, Nazik;
- Jenkinson, Chris;
- Defronzo, Ralph A;
- Abdul-Ghani, Muhammad A
Publication type:
journal article
The Relationship Between β-Cell Function and Glycated Hemoglobin.
Published in:
Diabetes Care, 2011, v. 34, n. 4, p. 1006, doi. 10.2337/dc10-1352
By:
- KANAT, MUSTAFA;
- WINNIER, DIEDRE;
- NORTON, LUKE;
- ARAR, NAZIK;
- JENKINSON, CHRIS;
- DEFRONZO, RALPH A.;
- ABDUL-GHANI, MUTIAMMAD A.
Publication type:
Article
Impaired early- but not late-phase insulin secretion in subjects with impaired fasting glucose.
Published in:
Acta Diabetologica, 2011, v. 48, n. 3, p. 209, doi. 10.1007/s00592-011-0285-x
By:
- Kanat, Mustafa;
- Norton, Luke;
- Winnier, Diedre;
- Jenkinson, Chris;
- DeFronzo, Ralph;
- Abdul-Ghani, Muhammad
Publication type:
Article
Strong association between insulin-mediated glucose uptake and the 2-hour, not the fasting plasma glucose concentration, in the normal glucose tolerance range.
Published in:
2014
By:
- Winner, Diedre;
- Norton, Luke;
- Kanat, Mustafa;
- Arya, Ruth;
- Fourcaudot, Marcel;
- Hansis-Diarte, Andrea;
- Tripathy, Devjit;
- DeFronzo, Ralph A;
- Jenkinson, Christopher P;
- Abdul-Ghani, Muhammad
Publication type:
journal article
Elevated Free Fatty Acids Attenuate the Insulin-Induced Suppression of PDK4 Gene Expression in Human Skeletal Muscle: Potential Role of Intramuscular Long-Chain Acyl-Coenzyme A.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2007, v. 92, n. 10, p. 3967, doi. 10.1210/jc.2007-1104
By:
- Tsintzas, Kostas;
- Chokkalingam, Kamal;
- Jewell, Kirsty;
- Norton, Luke;
- Macdonald, Ian A.;
- Constantin-Teodosiu, Dumitru
Publication type:
Article
Sodium-glucose co-transporter ( SGLT) and glucose transporter ( GLUT) expression in the kidney of type 2 diabetic subjects.
Published in:
Diabetes, Obesity & Metabolism, 2017, v. 19, n. 9, p. 1322, doi. 10.1111/dom.13003
By:
- Norton, Luke;
- Shannon, Christopher E.;
- Fourcaudot, Marcel;
- Hu, Cheng;
- Wang, Niansong;
- Ren, Wei;
- Song, Jun;
- Abdul‐Ghani, Muhammad;
- DeFronzo, Ralph A.;
- Ren, Jimmy;
- Jia, Weiping
Publication type:
Article
Mitochondrial pyruvate and fatty acid flux modulate MICU1-dependent control of MCU activity.
Published in:
Science Signaling, 2020, v. 13, n. 628, p. 1, doi. 10.1126/scisignal.aaz6206
By:
- Nemani, Neeharika;
- Dong, Zhiwei;
- Daw, Cassidy C.;
- Madaris, Travis R.;
- Ramachandran, Karthik;
- Enslow, Benjamin T.;
- Rubannelsonkumar, Cherubina S.;
- Shanmughapriya, Santhanam;
- Mallireddigari, Varshini;
- Maity, Soumya;
- SinghMalla, Pragya;
- Natarajanseenivasan, Kalimuthusamy;
- Hooper, Robert;
- Shannon, Christopher E.;
- Tourtellotte, Warren G.;
- Singh, Brij B.;
- Reeves, W. Brian;
- Sharma, Kumar;
- Norton, Luke;
- Srikantan, Subramanya
Publication type:
Article
On taxonomic issues, ontogenetic series and tooth replacement. Comments on Diphyodont tooth replacement of Brasilodon—A late Triassic eucynodont that challenges the time of origin of mammals by Cabreira et al.
Published in:
Journal of Anatomy, 2023, v. 242, n. 4, p. 737, doi. 10.1111/joa.13803
By:
- Abdala, Fernando;
- Norton, Luke A.;
- Jasinoski, Sandra C.;
- Botha, Jennifer;
- Fernandez, Vincent;
- Rubidge, Bruce;
- Gill, Pamela G.;
- Martinelli, Agustín G.
Publication type:
Article
Transcriptomic Identification of ADH1B as a Novel Candidate Gene for Obesity and Insulin Resistance in Human Adipose Tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES).
Published in:
PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0119941
By:
- Winnier, Deidre A.;
- Fourcaudot, Marcel;
- Norton, Luke;
- Abdul-Ghani, Muhammad A.;
- Hu, Shirley L.;
- Farook, Vidya S.;
- Coletta, Dawn K.;
- Kumar, Satish;
- Puppala, Sobha;
- Chittoor, Geetha;
- Dyer, Thomas D.;
- Arya, Rector;
- Carless, Melanie;
- Lehman, Donna M.;
- Curran, Joanne E.;
- Cromack, Douglas T.;
- Tripathy, Devjit;
- Blangero, John;
- Duggirala, Ravindranath;
- Göring, Harald H. H.
Publication type:
Article
Independent and combined effects of acute physiological hyperglycaemia and hyperinsulinaemia on metabolic gene expression in human skeletal muscle.
Published in:
Clinical Science, 2013, v. 124, n. 11, p. 675, doi. 10.1042/CS20120481
By:
- TSINTZAS, Kostas;
- NORTON, Luke;
- CHOKKALINGAM, Kamal;
- NIZAMANI, Nusrat;
- COOPER, Scott;
- STEPHENS, Francis;
- BILLETER, Rudolf;
- BENNETT, Andrew
Publication type:
Article
Pioglitazone inhibits mitochondrial pyruvate metabolism and glucose production in hepatocytes.
Published in:
FEBS Journal, 2017, v. 284, n. 3, p. 451, doi. 10.1111/febs.13992
By:
- Shannon, Christopher E.;
- Daniele, Giuseppe;
- Galindo, Cynthia;
- Abdul ‐ Ghani, Muhammad A.;
- DeFronzo, Ralph A.;
- Norton, Luke
Publication type:
Article
Tooth replacement patterns in the Early Triassic epicynodont Galesaurus planiceps (Therapsida, Cynodontia).
Published in:
PLoS ONE, 2020, v. 15, n. 12, p. 1, doi. 10.1371/journal.pone.0243985
By:
- Norton, Luke A.;
- Abdala, Fernando;
- Rubidge, Bruce S.;
- Botha, Jennifer
Publication type:
Article
Reappraisal of the envenoming capacity of Euchambersia mirabilis (Therapsida, Therocephalia) using μCT-scanning techniques.
Published in:
PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0172047
By:
- Benoit, Julien;
- Norton, Luke A.;
- Manger, Paul R.;
- Rubidge, Bruce S.
Publication type:
Article
Tooth replacement in the non-mammalian cynodont Cynosaurus suppostus (Therapsida) from the late Permian of South Africa.
Published in:
Journal of Vertebrate Paleontology, 2021, v. 41, n. 4, p. 1, doi. 10.1080/02724634.2021.2001650
By:
- Norton, Luke A.;
- Abdala, Fernando;
- Rubidge, Bruce S.;
- Botha, Jennifer
Publication type:
Article
Linkage of Type 2 Diabetes on Chromosome 9p24 in Mexican Americans: Additional Evidence from the Veterans Administration Genetic Epidemiology Study (VAGES).
Published in:
Human Heredity, 2013, v. 76, n. 1, p. 36, doi. 10.1159/000354849
By:
- Farook, Vidya S.;
- Coletta, Dawn K.;
- Puppala, Sobha;
- Schneider, Jennifer;
- Chittoor, Geetha;
- Hu, Shirley L.;
- Winnier, Deidre A.;
- Norton, Luke;
- Dyer, Thomas D.;
- Arya, Rector;
- Cole, Shelley A.;
- Carless, Melanie;
- Göring, Harald H.;
- Almasy, Laura;
- Mahaney, Michael C.;
- Comuzzie, Anthony G.;
- Curran, Joanne E.;
- Blangero, John;
- Duggirala, Ravindranath;
- Lehman, Donna M.
Publication type:
Article
The tumor suppressor TMEM127 regulates insulin sensitivity in a tissue-specific manner.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12661-0
By:
- Srikantan, Subramanya;
- Deng, Yilun;
- Cheng, Zi-Ming;
- Luo, Anqi;
- Qin, Yuejuan;
- Gao, Qing;
- Sande-Docor, Glaiza-Mae;
- Tao, Sifan;
- Zhang, Xingyu;
- Harper, Nathan;
- Shannon, Chris E.;
- Fourcaudot, Marcel;
- Li, Zhi;
- Kasinath, Balakuntalam S.;
- Harrison, Stephen;
- Ahuja, Sunil;
- Reddick, Robert L.;
- Dong, Lily Q.;
- Abdul-Ghani, Muhammad;
- Norton, Luke
Publication type:
Article
Effects of Sustained Hyperglycemia on Skeletal Muscle Lipids in Healthy Subjects.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 8, p. e3177, doi. 10.1210/clinem/dgac306
By:
- Shannon, Christopher E.;
- Merovci, Aurora;
- Fourcaudot, Marcel;
- Tripathy, Devjit;
- Abdul-Ghani, Muhammad;
- Hu Wang;
- Xianlin Han;
- Norton, Luke;
- DeFronzo, Ralph A.
Publication type:
Article
Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 2, p. 509, doi. 10.1172/JCI70704
By:
- Merovci, Aurora;
- Solis-Herrera, Carolina;
- Daniele, Giuseppe;
- Eldor, Roy;
- Fiorentino, Teresa Vanessa;
- Tripathy, Devjit;
- Xiong, Juan;
- Perez, Zandra;
- Norton, Luke;
- Abdul-Ghani, Muhammad A.;
- DeFronzo, Ralph A.
Publication type:
Article
478 Magnetic Resonance Biomarkers of Metabolic Dysfunction-Associated Steatotic Liver Disease.
Published in:
2024
By:
- Brown, Marissa;
- Moody, Alexander;
- Vasquez, Juan;
- Blangero, John;
- Norton, Luke;
- Clarke, Geoffrey
Publication type:
Abstract
Further evidence supporting a potential role for ADH1B in obesity.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80563-z
By:
- Morales, Liza D.;
- Cromack, Douglas T.;
- Tripathy, Devjit;
- Fourcaudot, Marcel;
- Kumar, Satish;
- Curran, Joanne E.;
- Carless, Melanie;
- Göring, Harald H. H.;
- Hu, Shirley L.;
- Lopez-Alvarenga, Juan Carlos;
- Garske, Kristina M.;
- Pajukanta, Päivi;
- Small, Kerrin S.;
- Glastonbury, Craig A.;
- Das, Swapan K.;
- Langefeld, Carl;
- Hanson, Robert L.;
- Hsueh, Wen-Chi;
- Norton, Luke;
- Arya, Rector
Publication type:
Article
The mechanisms of genome-wide target gene regulation by TCF7L2 in liver cells.
Published in:
Nucleic Acids Research, 2014, v. 42, n. 22, p. 13646, doi. 10.1093/nar/gku1225
By:
- Norton, Luke;
- Xi Chen;
- Fourcaudot, Marcel;
- Acharya, Nikhil K.;
- DeFronzo, Ralph A.;
- Heikkinen, Sami
Publication type:
Article
First CT‐assisted study of the palate and postcrania of Diarthrognathus broomi (Cynodontia, Probainognathia).
Published in:
Anatomical Record: Advances in Integrative Anatomy & Evolutionary Biology, 2024, v. 307, n. 4, p. 1538, doi. 10.1002/ar.25363
By:
- Lund, Erin S.;
- Norton, Luke A.;
- Benoit, Julien
Publication type:
Article
Increased lipid availability for three days reduces whole body glucose uptake, impairs muscle mitochondrial function and initiates opposing effects on PGC-1α promoter methylation in healthy subjects.
Published in:
PLoS ONE, 2017, v. 12, n. 12, p. 1, doi. 10.1371/journal.pone.0188208
By:
- Eldor, Roy;
- Norton, Luke;
- Fourcaudot, Marcel;
- Galindo, Cynthia;
- DeFronzo, Ralph A.;
- Abdul-Ghani, Muhammad
Publication type:
Article
257-OR: Short-Term Hyperglucagonemia Induces Adipose Tissue Insulin Resistance and Inflammation In Vivo.
Published in:
Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-257-OR
By:
- CHEN, XI;
- FOURCAUDOT, MARCEL;
- NORTON, LUKE;
- DEFRONZO, RALPH A.;
- TRIPATHY, DEVJIT
Publication type:
Article
1914-P: Prolonged (12-Hour) Glucagon Infusion Stimulates Adipocyte Lipolysis and Inflammation In Vivo in Humans.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1914-P
By:
- TRIPATHY, DEVJIT;
- FOURCAUDOT, MARCEL;
- NORTON, LUKE;
- DEFRONZO, RALPH A.;
- CHEN, XI
Publication type:
Article
1770-P: Further Evidence Supporting a Potential Role for ADH1B in Obesity.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1770-P
By:
- JENKINSON, CHRIS;
- MORALES, LIZA D.;
- TRIPATHY, DEVJIT;
- HU, SHIRLEY L.;
- LOPEZ-ALVARENGA, JUAN C.;
- DUGGIRALA, RAVINDRANATH;
- DEFRONZO, RALPH A.;
- MUMMIDI, SRINIVAS;
- ARYA, RECTOR;
- NORTON, LUKE;
- BLANGERO, JOHN;
- DIAZ-BADILLO, ALVARO
Publication type:
Article
165-LB: The SGLT2 Inhibitor Canagliflozin Prevents Increased Lipid Oxidation in the Heart following High-Fat Feeding.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-165-LB
By:
- FLORES, ITZEL;
- SHANNON, CHRIS;
- FOURCAUDOT, MARCEL;
- BAKEWELL, TERRY;
- NORTON, LUKE
Publication type:
Article
1898-P: The Role of the Diabetes Gene and Wnt Pathway Effector TCF7L2 in Hepatic Metabolic Zonation.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1898-P
By:
- AYALA, IRISCILLA I.;
- DEFRONZO, RALPH A.;
- NORTON, LUKE
Publication type:
Article
1861-P: Pioglitazone Modulates Hepatic Pyruvate Dehydrogenase and TCA Cycle Flux.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1861-P
By:
- SHANNON, CHRIS;
- RAGAVAN, MUKUNDAN;
- DEFRONZO, RALPH A.;
- MERRITT, MATTHEW;
- NORTON, LUKE
Publication type:
Article
Effect of Chronic Hyperglycemia on Glucose Metabolism in Subjects With Normal Glucose Tolerance.
Published in:
2018
By:
- Shannon, Chris;
- Merovci, Aurora;
- Xiong, Juan;
- Tripathy, Devjit;
- Lorenzo, Felipe;
- McClain, Donald;
- Abdul-Ghani, Muhammad;
- Norton, Luke;
- DeFronzo, Ralph A.
Publication type:
journal article
The Diabetes Gene and Wnt Pathway Effector TCF7L2 Regulates Adipocyte Development and Function.
Published in:
Diabetes, 2018, v. 67, n. 4, p. 554, doi. 10.2337/db17-0318
By:
- Xi Chen;
- Ayala, Iriscilla;
- Shannon, Chris;
- Fourcaudot, Marcel;
- Acharya, Nikhil K.;
- Jenkinson, Christopher P.;
- Heikkinen, Sami;
- Norton, Luke
Publication type:
Article
Empagliflozin and Kinetics of Renal Glucose Transport in Healthy Individuals and Individuals With Type 2 Diabetes.
Published in:
2017
By:
- Al-Jobori, Hussein;
- Daniele, Giuseppe;
- Cersosimo, Eugenio;
- Triplitt, Curtis;
- Mehta, Rucha;
- Norton, Luke;
- DeFronzo, Ralph A.;
- Abdul-Ghani, Muhammad
Publication type:
journal article
Novel Hypothesis to Explain Why SGLT2 Inhibitors Inhibit Only 30-50% of Filtered Glucose Load in Humans.
Published in:
Diabetes, 2013, v. 62, n. 10, p. 3324, doi. 10.2337/db13-0604
By:
- Abdul-Ghani, Muhammad A.;
- DeFronzo, Ralph A.;
- Norton, Luke
Publication type:
Article
Distinct β-cell defects in impaired fasting glucose and impaired glucose tolerance.
Published in:
2012
By:
- Kanat M;
- Mari A;
- Norton L;
- Winnier D;
- Defronzo RA;
- Jenkinson C;
- Abdul-Ghani MA;
- Kanat, Mustafa;
- Mari, Andrea;
- Norton, Luke;
- Winnier, Diedre;
- DeFronzo, Ralph A;
- Jenkinson, Chris;
- Abdul-Ghani, Muhammad A
Publication type:
journal article
Distinct β-Cell Defects in Impaired Fasting Glucose and Impaired Glucose Tolerance.
Published in:
Diabetes, 2012, v. 61, n. 2, p. 447, doi. 10.2337/db11-0995
By:
- Kanat, Mustafa;
- Mari, Andrea;
- Norton, Luke;
- Winnier, Diedre;
- DeFronzo, Ralph A.;
- Jenkinson, Chris;
- Abdul-Ghani, Muhammad A.
Publication type:
Article