Works by North, Brian J.

Results: 24

SIRT1 Regulates HIV Transcription via Tat Deacetylation.

Published in:

PLoS Biology, 2005, v. 3, n. 2, p. 1, doi. 10.1371/journal.pbio.0030041

By:

Pagans, Sara;
Pedal, Angelika;
North, Brian J;
Kaehlcke, Katrin;
Marshall, Brett L;
Dorr, Alexander;
Hetzer-Egger, Claudia;
Henklein, Peter;
Frye, Roy;
McBurney, Michael W;
Hruby, Henning;
Jung, Manfred;
Verdin, Eric;
Ott, Melanie

Publication type:

Article

Physiological relevance of post-translational regulation of the spindle assembly checkpoint protein BubR1.

Published in:

Cell & Bioscience, 2021, v. 11, n. 1, p. 1, doi. 10.1186/s13578-021-00589-2

By:

Bloom, Celia R.;
North, Brian J.

Publication type:

Article

SCF<sup>β-TRCP</sup> E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation.

Published in:

Protein & Cell, 2018, v. 9, n. 10, p. 879, doi. 10.1007/s13238-018-0510-2

By:

Ci, Yanpeng;
Li, Xiaoning;
Chen, Maorong;
Zhong, Jiateng;
North, Brian J.;
Inuzuka, Hiroyuki;
He, Xi;
Li, Yu;
Guo, Jianping;
Dai, Xiangpeng

Publication type:

Article

SCFβ‐TrCP ubiquitinates CHK1 in an AMPK‐dependent manner in response to glucose deprivation.

Published in:

Molecular Oncology, 2019, v. 13, n. 2, p. 307, doi. 10.1002/1878-0261.12403

By:

Ma, Ying;
Cui, Danrui;
Xiong, Xiufang;
Inuzuka, Hiroyuki;
Wei, Wenyi;
Sun, Yi;
North, Brian J.;
Zhao, Yongchao

Publication type:

Article

Genetic fusions favor tumorigenesis through degron loss in oncogenes.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26871-y

By:

Liu, Jing;
Tokheim, Collin;
Lee, Jonathan D.;
Gan, Wenjian;
North, Brian J.;
Liu, X. Shirley;
Pandolfi, Pier Paolo;
Wei, Wenyi

Publication type:

Article

Unraveling the Molecular Nexus between GPCRs, ERS, and EMT.

Published in:

Mediators of Inflammation, 2021, p. 1, doi. 10.1155/2021/6655417

By:

Kumari, Niti;
Reabroi, Somrudee;
North, Brian J.

Publication type:

Article

Role of spindle assembly checkpoint proteins in gametogenesis and embryogenesis.

Published in:

Frontiers in Cell & Developmental Biology, 2025, p. 1, doi. 10.3389/fcell.2024.1491394

By:

Pun, Renju;
North, Brian J.

Publication type:

Article

Enhancement of pomalidomide anti-tumor response with ACY-241, a selective HDAC6 inhibitor.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0173507

By:

North, Brian J.;
Almeciga-Pinto, Ingrid;
Tamang, David;
Yang, Min;
Jones, Simon S.;
Quayle, Steven N.

Publication type:

Article

The Role of Molecular and Cellular Aging Pathways on Age-Related Hearing Loss.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 17, p. 9705, doi. 10.3390/ijms25179705

By:

Ege, Tuba;
Tao, Litao;
North, Brian J.

Publication type:

Article

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase.

Published in:

Journal of Cell Biology, 2002, v. 158, n. 4, p. 647, doi. 10.1083/jcb.200205057

By:

Schwer, Bjorn;
North, Brian J.;
Frye, Roy A.;
Ott, Melanie;
Verdin, Eric

Publication type:

Article

Risk factors for tumors of the brain and meninges: Results from the Adelaide adult brain tumor study.

Published in:

International Journal of Cancer, 1992, v. 51, n. 1, p. 20, doi. 10.1002/ijc.2910510105

By:

Ryan, Philip;
Lee, Marjorie W.;
North, J. Brian;
McMichael, Anthony J.

Publication type:

Article

Receptor‐mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

Published in:

EMBO Journal, 2020, v. 39, n. 24, p. 1, doi. 10.15252/embj.2020104948

By:

Ohnstad, Amelia E;
Delgado, Jose M;
North, Brian J;
Nasa, Isha;
Kettenbach, Arminja N;
Schultz, Sebastian W;
Shoemaker, Christopher J

Publication type:

Article

SIRT2 induces the checkpoint kinase BubR1 to increase lifespan.

Published in:

EMBO Journal, 2014, v. 33, n. 13, p. 1438, doi. 10.15252/embj.201386907

By:

North, Brian J;
Rosenberg, Michael A;
Jeganathan, Karthik B;
Hafner, Angela V;
Michan, Shaday;
Dai, Jing;
Baker, Darren J;
Cen, Yana;
Wu, Lindsay E;
Sauve, Anthony A;
Deursen, Jan M;
Rosenzweig, Anthony;
Sinclair, David A

Publication type:

Article

BubR1 Controls Heart Development by Promoting Expression of Cardiogenesis Regulators.

Published in:

Journal of the American Heart Association, 2025, v. 14, n. 6, p. 1, doi. 10.1161/JAHA.124.038286

By:

Pun, Renju;
Thapa, Aradhana;
Takafuji, Sylar R.;
Suzuki, Rexton M.;
Kay, Gabrielle F.;
Howard, Toni D.;
Kim, Michael H.;
North, Brian J.

Publication type:

Article

E3 ubiquitin ligases in cancer stem cells: key regulators of cancer hallmarks and novel therapeutic opportunities.

Published in:

Cellular Oncology (2211-3428), 2023, v. 46, n. 3, p. 545, doi. 10.1007/s13402-023-00777-x

By:

Zou, Qiang;
Liu, Meng;
Liu, Kewei;
Zhang, Yi;
North, Brian J.;
Wang, Bin

Publication type:

Article

The emerging roles of protein homeostasis‐governing pathways in Alzheimer's disease.

Published in:

Aging Cell, 2018, v. 17, n. 5, p. 1, doi. 10.1111/acel.12801

By:

Cheng, Ji;
North, Brian J.;
Zhang, Tao;
Dai, Xiangpeng;
Tao, Kaixiong;
Guo, Jianping;
Wei, Wenyi

Publication type:

Article

The LC3-interacting region of NBR1 is a protein interaction hub enabling optimal flux.

Published in:

Journal of Cell Biology, 2025, v. 224, n. 4, p. 1, doi. 10.1083/jcb.202407105

By:

North, Brian J.;
Ohnstad, Amelia E.;
Ragusa, Michael J.;
Shoemaker, Christopher J.

Publication type:

Article

Selective Sirt2 inhibition by ligand-induced rearrangement of the active site.

Published in:

Nature Communications, 2015, v. 6, n. 2, p. 6263, doi. 10.1038/ncomms7263

By:

Rumpf, Tobias;
Schiedel, Matthias;
Karaman, Berin;
Roessler, Claudia;
North, Brian J.;
Lehotzky, Attila;
Oláh, Judit;
Ladwein, Kathrin I.;
Schmidtkunz, Karin;
Gajer, Markus;
Pannek, Martin;
Steegborn, Clemens;
Sinclair, David A.;
Gerhardt, Stefan;
Ovádi, Judit;
Schutkowski, Mike;
Sippl, Wolfgang;
Einsle, Oliver;
Jung, Manfred

Publication type:

Article

Histone deacetylase HDAC8 associates with smooth muscle α-actin and is essential for smooth muscle cell contractility.

Published in:

FASEB Journal, 2005, v. 19, n. 8, p. 966, doi. 10.1096/fj.04-2303fje

By:

Waltregny, David;
Glénisson, Wendy;
Tran, Siv Ly;
North, Brian J.;
Verdin, Eric;
Colige, Alain;
Castronovo, Vincent

Publication type:

Article

Regulation of topoisomerase II stability and activity by ubiquitination and SUMOylation: clinical implications for cancer chemotherapy.

Published in:

Molecular Biology Reports, 2021, v. 48, n. 9, p. 6589, doi. 10.1007/s11033-021-06665-7

By:

Ma, Ying;
North, Brian J.;
Shu, Jianfeng

Publication type:

Article

Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.

Published in:

Science Signaling, 2017, v. 10, n. 466, p. 1, doi. 10.1126/scisignal.aai8026

By:

Nihira, Naoe T.;
Kohei Ogura;
Kouhei Shimizu;
North, Brian J.;
Jinfang Zhang;
Daming Gao;
Hiroyuki Inuzuka;
Wenyi Wei

Publication type:

Article

PAINFUL OPHTHALMOPLEGIA FOLLOWING TREATED SQUAMOUS CARCINOMA OF THE FOREHEAD: ORBITAL APEX INVOLVEMENT FROM CENTRIPETAL SPREAD VIA THE SUPRAORBITAL NERVE.

Published in:

Medical Journal of Australia, 1976, v. 1, n. 22, p. 657, doi. 10.5694/j.1326-5377.1976.tb140943.x

By:

MOORE, COLIN E.;
HOYT, WILLIAM F.;
NORTH, J. BRIAN

Publication type:

Article

The SCF<sub>β-TRCP</sub> E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.

Published in:

Science Signaling, 2017, v. 10, n. 460, p. 1, doi. 10.1126/scisignal.aah4117

By:

Kouhei Shimizu;
Hidefumi Fukushima;
Kohei Ogura;
Lien, Evan C.;
Nihira, Naoe Taira;
Jinfang Zhang;
North, Brian J.;
Guo, Ailan;
Katsuyuki Nagashima;
Tadashi Nakagawa;
Seira Hoshikawa;
Asami Watahiki;
Koji Okabe;
Aya Yamada;
Toker, Alex;
Asara, John M.;
Fukumoto, Satoshi;
Nakayama, Keiichi I.;
Nakayama, Keiko;
Hiroyuki Inuzuka

Publication type:

Article

Editorial: Post-translational modifications of proteins in cancer immunity and immunotherapy.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1006145

By:

Xiangpeng Dai;
Jinfang Zhang;
North, Brian J.;
Jianping Guo

Publication type:

Article