Works by Norman, Brendan P.


Results: 19
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    Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria.

    Published in:
    Metabolites (2218-1989), 2022, v. 12, n. 10, p. 927, doi. 10.3390/metabo12100927
    By:
    • Norman, Brendan P.;
    • Davison, Andrew S.;
    • Hickton, Bryony;
    • Ross, Gordon A.;
    • Milan, Anna M.;
    • Hughes, Andrew T.;
    • Wilson, Peter J. M.;
    • Sutherland, Hazel;
    • Hughes, Juliette H.;
    • Roberts, Norman B.;
    • Bou-Gharios, George;
    • Gallagher, James A.;
    • Ranganath, Lakshminarayan R.
    Publication type:
    Article
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    Comparing the Phenylalanine/Tyrosine Pathway and Related Factors between Keratopathy and No-Keratopathy Groups as Well as between Genders in Alkaptonuria during Nitisinone Treatment.

    Published in:
    Metabolites (2218-1989), 2022, v. 12, n. 8, p. 772, doi. 10.3390/metabo12080772
    By:
    • Ranganath, Lakshminarayan R.;
    • Milan, Anna M.;
    • Hughes, Andrew T.;
    • Davison, Andrew S.;
    • Khedr, Milad;
    • Imrich, Richard;
    • Rudebeck, Mattias;
    • Olsson, Birgitta;
    • Norman, Brendan P.;
    • Bou-Gharios, George;
    • Gallagher, James A.
    Publication type:
    Article
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    The Regulatory Role of MicroRNAs in Breast Cancer.

    Published in:
    International Journal of Molecular Sciences, 2019, v. 20, n. 19, p. 4940, doi. 10.3390/ijms20194940
    By:
    • Loh, Hui-Yi;
    • Norman, Brendan P.;
    • Lai, Kok-Song;
    • Rahman, Nik Mohd Afizan Nik Abd.;
    • Alitheen, Noorjahan Banu Mohamed;
    • Osman, Mohd Azuraidi
    Publication type:
    Article
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    Nitisinone causes acquired tyrosinosis in alkaptonuria.

    Published in:
    Journal of Inherited Metabolic Disease, 2020, v. 43, n. 5, p. 1014, doi. 10.1002/jimd.12229
    By:
    • Khedr, Milad;
    • Cooper, Maggie S.;
    • Hughes, Andrew T.;
    • Milan, Anna M.;
    • Davison, Andrew S.;
    • Norman, Brendan P.;
    • Sutherland, Hazel;
    • Jarvis, Jonathan C.;
    • Fitzgerald, Richard;
    • Markinson, Louise;
    • Psarelli, Eftychia‐Eirini;
    • Ghane, Parisa;
    • Deutz, Nicolaas E. P.;
    • Gallagher, James A.;
    • Ranganath, Lakshminarayan R.
    Publication type:
    Article
    12

    Homogentisic acid is not only eliminated by glomerular filtration and tubular secretion but also produced in the kidney in alkaptonuria.

    Published in:
    Journal of Inherited Metabolic Disease, 2020, v. 43, n. 4, p. 737, doi. 10.1002/jimd.12181
    By:
    • Ranganath, Lakshminarayan R.;
    • Milan, Anna M.;
    • Hughes, Andrew T.;
    • Khedr, Milad;
    • Davison, Andrew S.;
    • Shweihdi, Ella;
    • Norman, Brendan P.;
    • Hughes, Juliette H.;
    • Bygott, Helen;
    • Luangrath, Emily;
    • Fitzgerald, Richard;
    • Psarelli, Eftychia E.;
    • Kan, Christa;
    • Laan, Dinny;
    • Olsson, Birgitta;
    • Rudebeck, Mattias;
    • Mankowitz, Louise;
    • Sireau, Nicolas;
    • Arnoux, Jean‐Baptiste;
    • Le Quan Sang, Kim‐Hanh
    Publication type:
    Article
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    Increased prevalence of Parkinson's disease in alkaptonuria.

    Published in:
    Journal of Inherited Metabolic Disease Reports, 2023, v. 64, n. 4, p. 282, doi. 10.1002/jmd2.12367
    By:
    • Ranganath, Lakshminarayan;
    • Khedr, Milad;
    • Milan, Anna M.;
    • Davison, Andrew S.;
    • Norman, Brendan P.;
    • Janssen, Mirian C. H.;
    • Lock, Edward;
    • Bou‐Gharios, George;
    • Gallagher, James A.
    Publication type:
    Article
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    Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria.

    Published in:
    Human Molecular Genetics, 2019, v. 28, n. 23, p. 3928, doi. 10.1093/hmg/ddz234
    By:
    • Hughes, Juliette H.;
    • Liu, Ke;
    • Plagge, Antonius;
    • Wilson, Peter J.M.;
    • Sutherland, Hazel;
    • Norman, Brendan P;
    • Hughes, Andrew T.;
    • Keenan, Craig M;
    • Milan, Anna M.;
    • Sakai, Takao;
    • Ranganath, Lakshminarayan R.;
    • Gallagher, James A.;
    • Bou-Gharios, George
    Publication type:
    Article
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