Works by Norihiko Misawa

Results: 93

3-β-Glucosyl-3′-β-quinovosyl zeaxanthin, a novel carotenoid glycoside synthesized by Escherichia coli cells expressing the Pantoea ananatis carotenoid biosynthesis gene cluster.

Published in:

Applied Microbiology & Biotechnology, 2013, v. 97, n. 19, p. 8479, doi. 10.1007/s00253-013-5101-9

By:

Choi, Seon-Kang;
Osawa, Ayako;
Maoka, Takashi;
Hattan, Jun-ichiro;
Ito, Kei;
Uchiyama, Ai;
Suzuki, Mai;
Shindo, Kazutoshi;
Misawa, Norihiko

Publication type:

Article

Efficient functional analysis system for cyanobacterial or plant cytochromes P450 involved in sesquiterpene biosynthesis.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 90, n. 2, p. 467, doi. 10.1007/s00253-010-3062-9

By:

Harada, Hisashi;
Shindo, Kazutoshi;
Iki, Kanoko;
Teraoka, Ayuko;
Okamoto, Sho;
Yu, Fengnian;
Hattan, Jun-ichiro;
Utsumi, Ryutaro;
Misawa, Norihiko

Publication type:

Article

Bioconversion of substituted naphthalenes and β-eudesmol with the cytochrome P450 BM3 variant F87V.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 90, n. 1, p. 147, doi. 10.1007/s00253-010-3064-7

By:

Misawa, Norihiko;
Nodate, Miho;
Otomatsu, Toshihiko;
Shimizu, Keiko;
Kaido, Chie;
Kikuta, Miho;
Ideno, Akira;
Ikenaga, Hiroshi;
Ogawa, Jun;
Shimizu, Sakayu;
Shindo, Kazutoshi

Publication type:

Article

Novel approaches and achievements in biosynthesis of functional isoprenoids in Escherichia coli.

Published in:

Applied Microbiology & Biotechnology, 2009, v. 84, n. 6, p. 1021, doi. 10.1007/s00253-009-2166-6

By:

Harada, Hisashi;
Misawa, Norihiko

Publication type:

Article

Efficient synthesis of functional isoprenoids from acetoacetate through metabolic pathway-engineered Escherichia coli.

Published in:

Applied Microbiology & Biotechnology, 2009, v. 81, n. 5, p. 915, doi. 10.1007/s00253-008-1724-7

By:

Harada, Hisashi;
Yu, Fengnian;
Okamoto, Sho;
Kuzuyama, Tomohisa;
Utsumi, Ryutaro;
Misawa, Norihiko

Publication type:

Article

Characterization of two β-carotene ketolases, CrtO and CrtW, by complementation analysis in Escherichia coli.

Published in:

Applied Microbiology & Biotechnology, 2007, v. 75, n. 6, p. 1335, doi. 10.1007/s00253-007-0967-z

By:

Seon-Kang Choi;
Harada, Hisashi;
Matsuda, Satoru;
Misawa, Norihiko

Publication type:

Article

Rare carotenoids, (3 R)-saproxanthin and (3 R,2′ S)-myxol, isolated from novel marine bacteria ( Flavobacteriaceae) and their antioxidative activities.

Published in:

Applied Microbiology & Biotechnology, 2007, v. 74, n. 6, p. 1350, doi. 10.1007/s00253-006-0774-y

By:

Shindo, Kazutoshi;
Kikuta, Kana;
Suzuki, Atsuko;
Katsuta, Atsuko;
Kasai, Hiroaki;
Yasumoto-Hirose, Mina;
Matsuo, Yoshihide;
Misawa, Norihiko;
Takaichi, Shinichi

Publication type:

Article

Characterization of bacterial β-carotene 3,3′-hydroxylases, CrtZ, and P450 in astaxanthin biosynthetic pathway and adonirubin production by gene combination in Escherichia coli.

Published in:

Applied Microbiology & Biotechnology, 2006, v. 72, n. 6, p. 1238, doi. 10.1007/s00253-006-0426-2

By:

Choi, Seon-Kang;
Matsuda, Satoru;
Hoshino, Takayuki;
Peng, Xue;
Misawa, Norihiko

Publication type:

Article

Characterization of four Rhodococcus alcohol dehydrogenase genes responsible for the oxidation of aromatic alcohols.

Published in:

Applied Microbiology & Biotechnology, 2006, v. 71, n. 6, p. 824, doi. 10.1007/s00253-005-0204-6

By:

Xue Peng;
Taki, Hironori;
Komukai, Syoko;
Sekine, Mitsuo;
Kanoh, Kaneo;
Kasai, Hiroaki;
Seon-Kang Choi;
Omata, Seiha;
Tanikawa, Satoshi;
Harayama, Shigeaki;
Misawa, Norihiko

Publication type:

Article

Functional expression system for cytochrome P450 genes using the reductase domain of self-sufficient P450RhF from Rhodococcus sp. NCIMB 9784.

Published in:

Applied Microbiology & Biotechnology, 2006, v. 71, n. 4, p. 455, doi. 10.1007/s00253-005-0147-y

By:

Nodate, Miho;
Kubota, Mitsutoshi;
Misawa, Norihiko

Publication type:

Article

Pathway engineering for high-yield production of lutein in Escherichia coli.

Published in:

Synthetic Biology (23977000), 2021, v. 6, n. 1, p. 1, doi. 10.1093/synbio/ysab012

By:

Takemura, Miho;
Kubo, Akiko;
Watanabe, Asuka;
Sakuno, Hanayo;
Minobe, Yuka;
Sahara, Takehiko;
Murata, Masahiro;
Araki, Michihiro;
Harada, Hisashi;
Terada, Yoshinobu;
Yaoi, Katsuro;
Ohdan, Kohji;
Misawa, Norihiko

Publication type:

Article

Correlation Between Changes in Extraocular Muscles and Intraocular Pressure Following Anti-Inflammatory Therapy in Active Thyroid Eye Disease.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 5, p. 1480, doi. 10.3390/jcm14051480

By:

Haruna, Yusuke;
Tagami, Mizuki;
Tomita, Mami;
Sakai, Atsushi;
Misawa, Norihiko;
Asano, Kazuo;
Murai, Yusuke;
Yoshikawa, Atsuko;
Azumi, Atsushi;
Honda, Shigeru

Publication type:

Article

One-Year Outcome of Intravitreal Injection of Ranibizumab Biosimilar for Myopic Choroidal Neovascularization in Japanese Patients.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 16, p. 4641, doi. 10.3390/jcm13164641

By:

Tomita, Mami;
Yamamoto, Manabu;
Hirayama, Kumiko;
Kyo, Akika;
Misawa, Norihiko;
Kinari, Gen;
Kohno, Takeya;
Honda, Shigeru

Publication type:

Article

Switching to Intravitreal Brolucizumab after Ranibizumab or Aflibercept Using Treat and Extend Regimen for Neovascular Age-Related Macular Degeneration in Japanese Patients: 1-Year Results and Factors Associated with Treatment Responsiveness.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 15, p. 4375, doi. 10.3390/jcm13154375

By:

Hirayama, Kumiko;
Yamamoto, Manabu;
Honda, Shigeru;
Kyo, Akika;
Misawa, Norihiko;
Kohno, Takeya

Publication type:

Article

Relationship between Vitreous IL-6 Levels, Gender Differences and C-Reactive Protein (CRP) in a Blood Sample of Posterior Uveitis.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 5, p. 1720, doi. 10.3390/jcm12051720

By:

Sakai, Atsushi;
Tagami, Mizuki;
Katsuyama-Yoshikawa, Atsuko;
Misawa, Norihiko;
Haruna, Yusuke;
Azumi, Atsushi;
Honda, Shigeru

Publication type:

Article

3′-Caffeoylquercetin Glycosides and 4′-Caffeoylkaempferol Glycosides—Novel Antioxidant Flavonoids Discovered in the Freesia Yellow Flowers.

Published in:

Antioxidants, 2025, v. 14, n. 2, p. 158, doi. 10.3390/antiox14020158

By:

Shindo, Kazutoshi;
Iwamoto, Nozomi;
Usami, Mayu;
Saito, Ayuna;
Sato, Miho;
Sugaya, Maho;
Miyashita, Nao;
Murahama, Minoru;
Higashimura, Yasuki;
Takemura, Miho;
Furihata, Kazuo;
Misawa, Norihiko

Publication type:

Article

Two Cases of Extremely High-IL-6 Pan-uveitis with Subretinal Exudation and Cell Migration.

Published in:

Ocular Immunology & Inflammation, 2022, v. 30, n. 7/8, p. 1577, doi. 10.1080/09273948.2021.1909071

By:

Tagami, Mizuki;
Misawa, Norihiko;
Sakai, Atsushi;
Honda, Shigeru

Publication type:

Article

Pathway engineering of Brassica napus seeds using multiple key enzyme genes involved in ketocarotenoid formation.

Published in:

Journal of Experimental Botany, 2009, v. 60, n. 4, p. 1319, doi. 10.1093/jxb/erp006

By:

Fujisawa, Masaki;
Takita, Eiji;
Harada, Hisashi;
Sakurai, Nozomu;
Suzuki, Hideyuki;
Ohyama, Kanji;
Shibata, Daisuke;
Misawa, Norihiko

Publication type:

Article

En-face widefield optical coherence tomography angiography for understanding vascular networks changes in two cases of acute retinal necrosis.

Published in:

2023

By:

Tomita, Mami;
Tagami, Mizuki;
Misawa, Norihiko;
Sakai, Atsushi;
Haruna, Yusuke;
Honda, Shigeru

Publication type:

Case Study

Relationship between ultra-widefield optical coherence tomography and ophthalmoscopy for detecting posterior inflammation in posterior uveitis and panuveitis.

Published in:

PLoS ONE, 2023, v. 18, n. 2, p. 1, doi. 10.1371/journal.pone.0281714

By:

Misawa, Norihiko;
Tagami, Mizuki;
Sakai, Atsushi;
Haruna, Yusuke;
Honda, Shigeru

Publication type:

Article

FOXP3 and CXCR4-positive regulatory T cells in the tumor stroma as indicators of tumor immunity in the conjunctival squamous cell carcinoma microenvironment.

Published in:

PLoS ONE, 2022, v. 17, n. 3, p. 1, doi. 10.1371/journal.pone.0263895

By:

Tagami, Mizuki;
Kakehashi, Anna;
Katsuyama-Yoshikawa, Atsuko;
Misawa, Norihiko;
Sakai, Atsushi;
Wanibuchi, Hideki;
Azumi, Atsushi;
Honda, Shigeru

Publication type:

Article

Intraoperative alteration in the vital signs of diabetic patients during cataract surgery with local anesthesia.

Published in:

PLoS ONE, 2022, v. 17, n. 3, p. 1, doi. 10.1371/journal.pone.0265135

By:

Kojima, Yuka;
Misawa, Norihiko;
Yamamoto, Tatsunori;
Honda, Shigeru

Publication type:

Article

Elevation of the provitamin A content of transgenic tomato plants.

Published in:

Nature Biotechnology, 2000, v. 18, n. 6, p. 666, doi. 10.1038/76523

By:

Römer, Susanne;
Fraser, Paul D.;
Kiano, Joy W.;
Shipton, Cathie A.;
Misawa, Norihiko;
Schuch, Wolfgang;
Bramley, Peter M.

Publication type:

Article

Safety and efficacy of 27-gauge transconjunctival vitrectomy for the diagnosis of posterior uveitis or pan uveitis of unknown origin.

Published in:

2022

By:

Sakai, Atsushi;
Tagami, Mizuki;
Misawa, Norihiko;
Yamamoto, Manabu;
Kohno, Takeya;
Honda, Shigeru

Publication type:

journal article

Visual outcomes and choroidal thickness associated with human leukocyte antigen DRB1*04 in unclassifiable uveitis in Japanese patients.

Published in:

2021

By:

Misawa, Norihiko;
Tagami, Mizuki;
Sakai, Atsushi;
Kohno, Takeya;
Honda, Shigeru

Publication type:

journal article

Elucidation of the whole carotenoid biosynthetic pathway of aphids at the gene level and arthropodal food chain involving aphids and the red dragonfly.

Published in:

BMC Zoology, 2021, v. 6, n. 1, p. 1, doi. 10.1186/s40850-021-00082-w

By:

Takemura, Miho;
Maoka, Takashi;
Koyanagi, Takashi;
Kawase, Naoki;
Nishida, Ritsuo;
Tsuchida, Tsutomu;
Hironaka, Mantaro;
Ueda, Tetsuyuki;
Misawa, Norihiko

Publication type:

Article

Cloning and functional analysis of alkB genes in Alcanivorax borkumensis SK2.

Published in:

Environmental Microbiology, 2004, v. 6, n. 3, p. 191, doi. 10.1046/j.1462-2920.2003.00550.x

By:

Hara, Akihiro;
Baik, Sang-ho;
Syutsubo, Kazuaki;
Misawa, Norihiko;
Smits, Theo H. M.;
van Beilen, Jan B.;
Harayama, Shigeaki

Publication type:

Article

Biosynthesis of astaxanthin in tobacco leaves by transplastomic engineering.

Published in:

Plant Journal, 2008, v. 55, n. 5, p. 857, doi. 10.1111/j.1365-313X.2008.03559.x

By:

Hasunuma, Tomohisa;
Miyazawa, Shin-Ichi;
Yoshimura, Satomi;
Shinzaki, Yuki;
Tomizawa, Ken-Ichi;
Shindo, Kazutoshi;
Choi, Seon-Kang;
Misawa, Norihiko;
Miyake, Chikahiro

Publication type:

Article

Metabolic engineering of ketocarotenoid formation in higher plants.

Published in:

Plant Journal, 2004, v. 39, n. 4, p. 477, doi. 10.1111/j.1365-313X.2004.02151.x

By:

Ralley, Louise;
Enfissi, Eugenia M. A.;
Misawa, Norihiko;
Schuch, Wolfgang;
Bramley, Peter M.;
Fraser, Paul D.

Publication type:

Article

cDNA Cloning and Functional Analyses of Ashitaba (Angelica keiskei) Sesquiterpene Synthase Genes.

Published in:

Journal of Oleo Science, 2020, v. 69, n. 7, p. 711, doi. 10.5650/jos.ess19275

By:

Kurin Iimura;
Jun-ichiro Hattan;
Norihiko Misawa;
Kazutoshi Shindo

Publication type:

Article

Isolation and Functional Characterization of New Terpene Synthase Genes from Traditional Edible Plants.

Published in:

Journal of Oleo Science, 2018, v. 67, n. 10, p. 1235, doi. 10.5650/jos.ess18163

By:

Jun-ichiro Hattan;
Kazutoshi Shindo;
Tetsuya Sasaki;
Norihiko Misawa

Publication type:

Article

Expression, intracellular localization, and mutation of EGFR in conjunctival squamous cell carcinoma and the association with prognosis and treatment.

Published in:

PLoS ONE, 2020, v. 15, n. 8, p. 1, doi. 10.1371/journal.pone.0238120

By:

Sakai, Atsushi;
Tagami, Mizuki;
Kakehashi, Anna;
Katsuyama-Yoshikawa, Atsuko;
Misawa, Norihiko;
Wanibuchi, Hideki;
Azumi, Atsushi;
Honda, Shigeru

Publication type:

Article

A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet.

Published in:

FEBS Journal, 2011, v. 278, n. 16, p. 2892, doi. 10.1111/j.1742-4658.2011.08211.x

By:

Okamoto, Sho;
Yu, Fengnian;
Harada, Hisashi;
Okajima, Toshihide;
Hattan, Jun-ichiro;
Misawa, Norihiko;
Utsumi, Ryutaro

Publication type:

Article

Photoprotection vs. Photoinhibition of Photosystem II in Transplastomic Lettuce (Lactuca sativa) Dominantly Accumulating Astaxanthin.

Published in:

Plant & Cell Physiology, 2016, v. 57, n. 7, p. 1518, doi. 10.1093/pcp/pcv187

By:

Ritsuko Fujii;
Nami Yamano;
Hideki Hashimoto;
Norihiko Misawa;
Kentaro Ifuku

Publication type:

Article

Carotenoid Analysis of a Liverwort Marchantia polymorpha and Functional Identification of its Lycopene β- and ɛ-Cyclase Genes.

Published in:

Plant & Cell Physiology, 2014, v. 55, n. 1, p. 194, doi. 10.1093/pcp/pct170

By:

Takemura, Miho;
Maoka, Takashi;
Misawa, Norihiko

Publication type:

Article

Characterization of Cyanobacterial Carotenoid Ketolase CrtW and Hydroxylase CrtR by Complementation Analysis in Escherichia coli.

Published in:

Plant & Cell Physiology, 2008, v. 49, n. 12, p. 1867, doi. 10.1093/pcp/pcn169

By:

Takuya Makino;
Hisashi Harada;
Hiroshi Ikenaga;
Satoru Matsuda;
Shinichi Takaichi;
Kazutoshi Shindo;
Gerhard Sandmann;
Takehiko Ogata;
Norihiko Misawa

Publication type:

Article

Phytoene Desaturase, CrtI, of the Purple Photosynthetic Bacterium, Rubrivivax gelatinosus, Produces both Neurosporene and Lycopene.

Published in:

Plant & Cell Physiology, 2001, v. 42, n. 10, p. 1112, doi. 10.1093/pcp/pce140

By:

Harada, Jiro;
Nagashima, Kenji V. P.;
Takaichi, Shinichi;
Misawa, Norihiko;
Matsuura, Katsumi;
Shimada, Keizo

Publication type:

Article

rβCarotene Hydroxylase Gene from the Cyanobacterium Synechocystis sp. PCC6803.

Published in:

Plant & Cell Physiology, 1998, v. 39, n. 5, p. 560, doi. 10.1093/oxfordjournals.pcp.a029405

By:

Masamoto, Kazumori;
Misawa, Norihiko;
Kaneko, Takakazu;
Kikuno, Reiko;
Toh, Hiroyuki

Publication type:

Article

Methyl 5-glucosyl-5,6-dihydro-apo-4,4′-lycopenoate, a novel antioxidative glyco-C<sub>30</sub>-carotenoic acid produced by a marine bacterium Planococcus maritimus.

Published in:

Journal of Antibiotics, 2014, v. 67, n. 10, p. 731, doi. 10.1038/ja.2014.52

By:

Shindo, Kazutoshi;
Endo, Megumi;
Miyake, Yuriko;
Wakasugi, Kyoko;
Morritt, David;
Bramley, Peter M;
Fraser, Paul D;
Kasai, Hiroaki;
Misawa, Norihiko

Publication type:

Article

Cloning and characterization of a novel gene that encodes ( S)-β-bisabolene synthase from ginger, Zingiber officinale.

Published in:

Planta: An International Journal of Plant Biology, 2010, v. 232, n. 1, p. 121, doi. 10.1007/s00425-010-1137-6

By:

Fujisawa, Masaki;
Harada, Hisashi;
Kenmoku, Hiromichi;
Mizutani, Satoru;
Misawa, Norihiko

Publication type:

Article

Erratum to: Cloning and characterization of a novel gene that encodes ( S)- β-bisabolene synthase from ginger, Zingiber officinale.

Published in:

2010

By:

Fujisawa, Masaki;
Harada, Hisashi;
Kenmoku, Hiromichi;
Mizutani, Satoru;
Misawa, Norihiko

Publication type:

Correction Notice

Molecular cloning and functional characterization of α-humulene synthase, a possible key enzyme of zerumbone biosynthesis in shampoo ginger ( Zingiber zerumbet Smith).

Published in:

Planta: An International Journal of Plant Biology, 2008, v. 227, n. 6, p. 1291, doi. 10.1007/s00425-008-0700-x

By:

Fengnian Yu;
Okamto, Sho;
Nakasone, Kaoru;
Adachi, Kyoko;
Matsuda, Satoru;
Harada, Hisashi;
Misawa, Norihiko;
Utsumi, Ryutaro

Publication type:

Article

A carotenoid synthesis gene cluster from Algoriphagus sp. KK10202C with a novel fusion-type lycopene β-cyclase gene.

Published in:

Molecular Genetics & Genomics, 2006, v. 276, n. 1, p. 79, doi. 10.1007/s00438-006-0121-0

By:

Luan Tao;
Henry Yao;
Hiroaki Kasai;
Norihiko Misawa;
Qiong Cheng

Publication type:

Article

Serum PD-1 regulation and PD-1 expression of CD4+Foxp3+ regulatory T cells in patients in thyroid eye disease associated with immunosuppression treatment.

Published in:

Frontiers in Ophthalmology, 2024, p. 1, doi. 10.3389/fopht.2024.1491053

By:

Sakai, Atsushi;
Tagami, Mizuki;
Misawa, Norihiko;
Haruna, Yusuke;
Tomita, Mami;
Honda, Shigeru

Publication type:

Article

Expression of an Erwinia phytoene desaturase gene not only confers multiple resistance to herbicides interfering with carotenoid biosynthesis but also alters xanthophyll metabolism in transgenic plants.

Published in:

Plant Journal, 1994, v. 6, n. 4, p. 481, doi. 10.1046/j.1365-313X.1994.6040481.x

By:

Misawa, Norihiko;
Masamoto, Kazumori;
Hori, Tamaki;
Ohtani, Takeshi;
Böger, Peter;
Sandmann, Gerhard

Publication type:

Article

Functional expression of the Erwinia uredovora carotenoid biosynthesis gene crtl in transgenic plants showing an increase of β-carotene biosynthesis activity and resistance to the bleaching herbicide norflurazon.

Published in:

Plant Journal, 1993, v. 4, n. 5, p. 833, doi. 10.1046/j.1365-313X.1993.04050833.x

By:

Misawa, Norihiko;
Yamano, Shigeyuki;
Linden, Hartmut;
Felipe, Maria R.;
Lucas, Mercedes;
Ikenaga, Hiroshi;
Sandmann, Gerhard

Publication type:

Article

Heterologous production of novel and rare C<sub>30</sub>-carotenoids using Planococcus carotenoid biosynthesis genes.

Published in:

Microbial Cell Factories, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12934-021-01683-3

By:

Takemura, Miho;
Takagi, Chiharu;
Aikawa, Mayuri;
Araki, Kanaho;
Choi, Seon-Kang;
Itaya, Mitsuhiro;
Shindo, Kazutoshi;
Misawa, Norihiko

Publication type:

Article

Cloning and characterization of the astaxanthin biosynthetic gene encoding phytoene desaturase of Xanthophyllomyces dendrorhous.

Published in:

Biotechnology & Bioengineering, 1999, v. 63, n. 6, p. 750, doi. 10.1002/(SICI)1097-0290(19990620)63:6<750::AID-BIT13>3.0.CO;2-7

By:

Verdoes, Jan C.;
Misawa, Norihiko;
van Ooyen, Albert J. J.

Publication type:

Article

Production of lycopene by the food yeast, Candida utilis that does not naturally synthesize carotenoid.

Published in:

Biotechnology & Bioengineering, 1998, v. 58, n. 2/3, p. 306, doi. 10.1002/(SICI)1097-0290(19980420)58:2/3<306::AID-BIT29>3.0.CO;2-8

By:

Miura, Yutaka;
Kondo, Keiji;
Shimada, Hiroshi;
Saito, Toshiko;
Nakamura, Katsumi;
Misawa, Norihiko

Publication type:

Article

Immunohistochemical expression of Fibrillin-1 in idiopathic epiretinal membranes.

Published in:

Graefe's Archive of Clinical & Experimental Ophthalmology, 2025, v. 263, n. 2, p. 415, doi. 10.1007/s00417-024-06667-8

By:

Tien, Luu Viet;
Yamamoto, Manabu;
Tagami, Mizuki;
Misawa, Norihiko;
Honda, Shigeru

Publication type:

Article