Works matching AU Nokihara, Hiroshi

Results: 114

Comparison of Radiotherapy and Chemoradiotherapy for Locoregional Recurrence of Non-small-cell Lung Cancer Developing After Surgery.

Published in:

2017

By:

Shinji Nakamichi;
Hidehito Horinouchi;
Tetsuhiko Asao;
Yasushi Goto;
Shintaro Kanda;
Yutaka Fujiwara;
Hiroshi Nokihara;
Noboru Yamamoto;
Yoshinori Ito;
Shun-ichi Watanabe;
Yuichiro Ohe;
Nakamichi, Shinji;
Horinouchi, Hidehito;
Asao, Tetsuhiko;
Goto, Yasushi;
Kanda, Shintaro;
Fujiwara, Yutaka;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Ito, Yoshinori

Publication type:

journal article

Sequential Use of Anaplastic Lymphoma Kinase Inhibitors in Japanese Patients With ALK-Rearranged Non-Small-Cell Lung Cancer: A Retrospective Analysis.

Published in:

2017

By:

Tetsuhiko Asao;
Yutaka Fujiwara;
Itahashi, Kota;
Shinsuke Kitahara;
Yasushi Goto;
Hidehito Horinouchi;
Shintaro Kanda;
Hiroshi Nokihara;
Noboru Yamamoto;
Kazuhisa Takahashi;
Yuichiro Ohe;
Asao, Tetsuhiko;
Fujiwara, Yutaka;
Kitahara, Shinsuke;
Goto, Yasushi;
Horinouchi, Hidehito;
Kanda, Shintaro;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Takahashi, Kazuhisa

Publication type:

journal article

Comparison of Amrubicin and Weekly Cisplatin/Etoposide/Irinotecan in Patients With Relapsed Small-cell Lung Cancer.

Published in:

2017

By:

Hitomi Sumiyoshi Okuma;
Hidehito Horinouchi;
Shinsuke Kitahara;
Tetsuhiko Asao;
Kuniko Sunami;
Yasushi Goto;
Shintaro Kanda;
Yutaka Fujiwara;
Hiroshi Nokihara;
Noboru Yamamoto;
Yuichiro Ohe;
Okuma, Hitomi Sumiyoshi;
Horinouchi, Hidehito;
Kitahara, Shinsuke;
Asao, Tetsuhiko;
Sunami, Kuniko;
Goto, Yasushi;
Kanda, Shintaro;
Fujiwara, Yutaka;
Nokihara, Hiroshi

Publication type:

journal article

A Phase II Study of Ubenimex Combined With Pembrolizumab, Nab-Paclitaxel, and Carboplatin for Previously Untreated Advanced Squamous Non-Small-Cell Lung Cancer: TORG2241 (UBE-Q).

Published in:

Clinical Lung Cancer, 2024, v. 25, n. 1, p. 85, doi. 10.1016/j.cllc.2023.09.006

By:

Shinji Nakamichi;
Kaoru Kubota;
Kotone Matsuyama;
Toshihiro Misumi;
Toshiyuki Kozuki;
Shunichi Sugawara;
Katsuhiko Naoki;
Nobuaki Kobayashi;
Takehito Shukuya;
Tsuneo Shimokawa;
Masashi Ishihara;
Hiroshi Wakui;
Yukio Hosomi;
Hiroshi Tanaka;
Haruhiro Saito;
Shinobu Hosokawa;
Yuichi Takiguchi;
Takashi Kasai;
Hiroshi Nokihara;
Ryo Morita

Publication type:

Article

Phase 1 Study of Cabozantinib in Japanese Patients With Expansion Cohorts in Non-Small-Cell Lung Cancer.

Published in:

2019

By:

Nokihara, Hiroshi;
Nishio, Makoto;
Yamamoto, Noboru;
Fujiwara, Yutaka;
Horinouchi, Hidehito;
Kanda, Shintaro;
Horiike, Atsushi;
Ohyanagi, Fumiyoshi;
Yanagitani, Noriko;
Nguyen, Linh;
Yaron, Yifah;
Borgman, Anne;
Tamura, Tomohide

Publication type:

journal article

Atezolizumab in Japanese Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer: A Subgroup Analysis of the Phase 3 OAK Study.

Published in:

2018

By:

Hida, Toyoaki;
Kaji, Reiko;
Satouchi, Miyako;
Ikeda, Norihiko;
Horiike, Atsushi;
Nokihara, Hiroshi;
Seto, Takashi;
Kawakami, Tomohisa;
Nakagawa, Shintaro;
Kubo, Toshio

Publication type:

journal article

Reliability of Small Biopsy Samples Compared With Resected Specimens for the Determination of Programmed Death-Ligand 1 Expression in Non--Small-Cell Lung Cancer.

Published in:

Clinical Lung Cancer, 2015, v. 16, n. 5, p. 385, doi. 10.1016/j.cllc.2015.03.008

By:

Satoru Kitazono;
Yutaka Fujiwara;
Koji Tsuta;
Hirofumi Utsumi;
Shintaro Kanda;
Hidehito Horinouchi;
Hiroshi Nokihara;
Noboru Yamamoto;
Shinji Sasada;
Shun-ichi Watanabe;
Hisao Asamura;
Tomohide Tamura;
Yuichiro Ohe

Publication type:

Article

Clinicopathological Features in Young Patients Treated for Small-Cell Lung Cancer: Significance of Immunohistological and Molecular Analyses.

Published in:

Clinical Lung Cancer, 2014, v. 15, n. 3, p. 244, doi. 10.1016/j.cllc.2013.06.012

By:

Tomoko Katsui Taniyama;
Hiroshi Nokihara;
Koji Tsuta;
Hidehito Horinouchi;
Shintaro Kanda;
Yutaka Fujiwara;
Noboru Yamamoto;
Fumiaki Koizumi;
Mayu Yunokawa;
Tomohide Tamura

Publication type:

Article

Paclitaxel for relapsed small-cell lung cancer patients with idiopathic interstitial pneumonias.

Published in:

Molecular & Clinical Oncology, 2019, v. 10, n. 5, p. 541

By:

Saijo, Atsuro;
Hanibuchi, Masaki;
Ogino, Hirokazu;
Otsuka, Kenji;
Goto, Hisatsugu;
Nokihara, Hiroshi;
Nishioka, Yasuhiko

Publication type:

Article

Randomized phase II study of sequential carboplatin plus paclitaxel and gefitinib in chemotherapy-naïve patients with advanced or metastatic non-small-cell lung cancer: Long-term follow-up results.

Published in:

Molecular & Clinical Oncology, 2017, v. 6, n. 1, p. 56, doi. 10.3892/mco.2016.1076

By:

EMI KUBO;
NOBORU YAMAMOTO;
HIROSHI NOKIHARA;
YUTAKA FUJIWARA;
HIDEHITO HORINOUCHI;
SHINTARO KANDA;
YASUSHI GOTO;
YUICHIRO OHE

Publication type:

Article

Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.

Published in:

JAMA Neurology, 2022, v. 79, n. 6, p. 575, doi. 10.1001/jamaneurol.2022.0901

By:

Oki, Ryosuke;
Izumi, Yuishin;
Fujita, Koji;
Miyamoto, Ryosuke;
Nodera, Hiroyuki;
Sato, Yasutaka;
Sakaguchi, Satoshi;
Nokihara, Hiroshi;
Kanai, Kazuaki;
Tsunemi, Taiji;
Hattori, Nobutaka;
Hatanaka, Yuki;
Sonoo, Masahiro;
Atsuta, Naoki;
Sobue, Gen;
Shimizu, Toshio;
Shibuya, Kazumoto;
Ikeda, Ken;
Kano, Osamu;
Nishinaka, Kazuto

Publication type:

Article

Correlation between immune-related adverse events and therapeutic effects of nivolumab in patients with malignant pleural mesothelioma.

Published in:

2021

By:

Yoneda, Hiroto;
Nokihara, Hiroshi;
Mitsuhashi, Atsushi;
Ozaki, Ryohiko;
Yabuki, Yohei;
Ogino, Hirokazu;
Otsuka, Kenji;
Nishioka, Yasuhiko

Publication type:

journal article

Pharmacodynamic change in plasma angiogenic proteins: a dose-escalation phase 1 study of the multi-kinase inhibitor lenvatinib.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-530

By:

Noriyuki Koyama;
Kenichi Saito;
Yuki Nishioka;
Wataru Yusa;
Noboru Yamamoto;
Yasuhide Yamada;
Hiroshi Nokihara;
Fumiaki Koizumi;
Kazuto Nishio;
Tomohide Tamura

Publication type:

Article

Pharmacodynamic change in plasma angiogenic proteins: a dose-escalation phase 1 study of the multi-kinase inhibitor lenvatinib

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 530, doi. 10.1186/1471-2407-14-530

By:

Noriyuki Koyama;
Kenichi Saito;
Yuki Nishioka;
Wataru Yusa;
Noboru Yamamoto;
Yasuhide Yamada;
Hiroshi Nokihara;
Fumiaki Koizumi;
Kazuto Nishio;
Tamura, Tomohide

Publication type:

Article

Pharmacodynamic change in plasma angiogenic proteins: a dose-escalation phase 1 study of the multi-kinase inhibitor lenvatinib.

Published in:

2014

By:

Koyama, Noriyuki;
Saito, Kenichi;
Nishioka, Yuki;
Yusa, Wataru;
Yamamoto, Noboru;
Yamada, Yasuhide;
Nokihara, Hiroshi;
Koizumi, Fumiaki;
Nishio, Kazuto;
Tamura, Tomohide

Publication type:

journal article

Early mortality factors in immune checkpoint inhibitor monotherapy for advanced or metastatic non-small cell lung cancer.

Published in:

Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 7, p. 3139, doi. 10.1007/s00432-022-04215-7

By:

Takeuchi, Eiji;
Kondo, Kensuke;
Okano, Yoshio;
Kunishige, Michihiro;
Kondo, Yoshihiro;
Kadota, Naoki;
Machida, Hisanori;
Hatakeyama, Nobuo;
Naruse, Keishi;
Ogino, Hirokazu;
Nokihara, Hiroshi;
Shinohara, Tsutomu;
Nishioka, Yasuhiko

Publication type:

Article

Perspectives of non-specialists on the potential to serve as ethics committee members.

Published in:

Journal of International Medical Research, 2019, v. 47, n. 5, p. 1868, doi. 10.1177/0300060518823941

By:

Kane, Chikako;
Takechi, Kenshi;
Chuma, Masayuki;
Nokihara, Hiroshi;
Takagai, Tomoko;
Yanagawa, Hiroaki

Publication type:

Article

Clinical trends among patients with asthma hospitalized for COVID-19 based on data from a nationwide database: an observational study.

Published in:

BMC Pulmonary Medicine, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12890-024-02917-x

By:

Tsukada, Akinari;
Terada-Hirashima, Junko;
Takasaki, Jin;
Nokihara, Hiroshi;
Izumi, Shinyu;
Hojo, Masayuki;
Sugiyama, Haruhito

Publication type:

Article

Gender Differences in Treatment Outcomes among Patients with Non-Small Cell Lung Cancer Given a Combination of Carboplatin and Paclitaxel.

Published in:

Oncology, 2008, v. 75, n. 3/4, p. 169, doi. 10.1159/000159268

By:

Harukaze Yamamoto;
Ikuo Sekine;
Kazuhiko Yamada;
Hiroshi Nokihara;
Noboru Yamamoto;
Hideo Kunitoh;
Yuichiro Ohe;
Tomohide Tamura

Publication type:

Article

Antipodoplanin antibody enhances the antitumor effects of CTLA‐4 blockade against malignant mesothelioma by natural killer cells.

Published in:

Cancer Science, 2024, v. 115, n. 2, p. 357, doi. 10.1111/cas.16046

By:

Yoneda, Hiroto;
Mitsuhashi, Atsushi;
Yoshida, Aito;
Ogino, Hirokazu;
Itakura, Satoshi;
Nguyen, Na Thi;
Nokihara, Hiroshi;
Sato, Seidai;
Shinohara, Tsutomu;
Hanibuchi, Masaki;
Abe, Shinji;
Kaneko, Mika K.;
Kato, Yukinari;
Nishioka, Yasuhiko

Publication type:

Article

S‐1 eliminates MDSCs and enhances the efficacy of PD‐1 blockade via regulation of tumor‐derived Bv8 and S100A8 in thoracic tumor.

Published in:

Cancer Science, 2023, v. 114, n. 2, p. 384, doi. 10.1111/cas.15620

By:

Nguyen, Na T.;
Mitsuhashi, Atsushi;
Ogino, Hirokazu;
Kozai, Hiroyuki;
Yoneda, Hiroto;
Afroj, Tania;
Sato, Seidai;
Nokihara, Hiroshi;
Shinohara, Tsutomu;
Nishioka, Yasuhiko

Publication type:

Article

Programmed death (PD)‐1/PD‐ligand 1 blockade mediates antiangiogenic effects by tumor‐derived CXCL10/11 as a potential predictive biomarker.

Published in:

Cancer Science, 2021, v. 112, n. 12, p. 4853, doi. 10.1111/cas.15161

By:

Mitsuhashi, Atsushi;
Kondoh, Kensuke;
Horikawa, Kazuki;
Koyama, Kazuya;
Nguyen, Na Thi;
Afroj, Tania;
Yoneda, Hiroto;
Otsuka, Kenji;
Ogino, Hirokazu;
Nokihara, Hiroshi;
Shinohara, Tsutomu;
Nishioka, Yasuhiko

Publication type:

Article

Five‐year safety and efficacy data from a phase Ib study of nivolumab and chemotherapy in advanced non‐small‐cell lung cancer.

Published in:

Cancer Science, 2020, v. 111, n. 6, p. 1933, doi. 10.1111/cas.14410

By:

Kanda, Shintaro;
Ohe, Yuichiro;
Goto, Yasushi;
Horinouchi, Hidehito;
Fujiwara, Yutaka;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Yamamoto, Takanori;
Tamura, Tomohide

Publication type:

Article

Clinical activity of ASP8273 in Asian patients with non‐small‐cell lung cancer with EGFR activating and T790M mutations.

Published in:

Cancer Science, 2018, v. 109, n. 9, p. 2852, doi. 10.1111/cas.13724

By:

Murakami, Haruyasu;
Nokihara, Hiroshi;
Hayashi, Hidetoshi;
Seto, Takashi;
Park, Keunchil;
Azuma, Koichi;
Tsai, Chun‐Ming;
Yang, James Chih‐Hsin;
Nishio, Makoto;
Kim, Sang‐We;
Kiura, Katsuyuki;
Inoue, Akira;
Takeda, Koji;
Kang, Jin‐Hyoung;
Nakagawa, Tomoki;
Takeda, Kentaro;
Akazawa, Rio;
Kaneko, Yuichiro;
Shimazaki, Masashi;
Morita, Satoshi

Publication type:

Article

Efficacy and safety of nivolumab in Japanese patients with advanced or recurrent squamous non-small cell lung cancer.

Published in:

Cancer Science, 2017, v. 108, n. 5, p. 1000, doi. 10.1111/cas.13225

By:

Hida, Toyoaki;
Nishio, Makoto;
Nogami, Naoyuki;
Ohe, Yuichiro;
Nokihara, Hiroshi;
Sakai, Hiroshi;
Satouchi, Miyako;
Nakagawa, Kazuhiko;
Takenoyama, Mitsuhiro;
Isobe, Hiroshi;
Fujita, Shiro;
Tanaka, Hiroshi;
Minato, Koichi;
Takahashi, Toshiaki;
Maemondo, Makoto;
Takeda, Koji;
Saka, Hideo;
Goto, Koichi;
Atagi, Shinji;
Hirashima, Tomonori

Publication type:

Article

Pharmacokinetic profiles of significant adverse events with crizotinib in Japanese patients with ABCB1 polymorphism.

Published in:

Cancer Science, 2016, v. 107, n. 8, p. 1117, doi. 10.1111/cas.12983

By:

Fujiwara, Yutaka;
Hamada, Akinobu;
Mizugaki, Hidenori;
Aikawa, Hiroaki;
Hata, Toshiyuki;
Horinouchi, Hidehito;
Kanda, Shintaro;
Goto, Yasushi;
Itahashi, Kota;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Ohe, Yuichiro

Publication type:

Article

Impact of KRAS mutation on response and outcome of patients with stage III non-squamous non-small cell lung cancer.

Published in:

Cancer Science, 2015, v. 106, n. 10, p. 1402, doi. 10.1111/cas.12740

By:

Yagishita, Shigehiro;
Horinouchi, Hidehito;
Sunami, Kuniko S.;
Kanda, Shintaro;
Fujiwara, Yutaka;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Sumi, Minako;
Shiraishi, Kouya;
Kohno, Takashi;
Furuta, Koh;
Tsuta, Koji;
Tamura, Tomohide;
Ohe, Yuichiro

Publication type:

Article

Brain metastases after definitive concurrent chemoradiotherapy in patients with stage III lung adenocarcinoma: Carcinoembryonic antigen as a potential predictive factor.

Published in:

Cancer Science, 2012, v. 103, n. 4, p. 756, doi. 10.1111/j.1349-7006.2012.02217.x

By:

Horinouchi, Hidehito;
Sekine, Ikuo;
Sumi, Minako;
Ito, Yoshinori;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Ohe, Yuichiro;
Tamura, Tomohide

Publication type:

Article

A Phase I, dose-finding and pharmacokinetic study of olaparib (AZD2281) in Japanese patients with advanced solid tumors*,†.

Published in:

Cancer Science, 2012, v. 103, n. 3, p. 504, doi. 10.1111/j.1349-7006.2011.02179.x

By:

Yamamoto, Noboru;
Nokihara, Hiroshi;
Yamada, Yasuhide;
Goto, Yasushi;
Tanioka, Maki;
Shibata, Takashi;
Yamada, Kazuhiko;
Asahina, Hajime;
Kawata, Toshio;
Shi, Xiaojin;
Tamura, Tomohide

Publication type:

Article

Innovator and generic cisplatin formulations: Comparison of renal toxicity.

Published in:

Cancer Science, 2011, v. 102, n. 1, p. 162, doi. 10.1111/j.1349-7006.2010.01764.x

By:

Sekine, Ikuo;
Kubota, Kaoru;
Tamura, Yosuke;
Asahina, Hajime;
Yamada, Kazuhiko;
Horinouchi, Hidehito;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Tamura, Tomohide

Publication type:

Article

Phase I study of TLR9 agonist PF-3512676 in combination with carboplatin and paclitaxel in patients with advanced non-small-cell lung cancer.

Published in:

Cancer Science, 2010, v. 101, n. 1, p. 188, doi. 10.1111/j.1349-7006.2009.01361.x

By:

Yamada, Kazuhiko;
Nakao, Masao;
Fukuyama, Chikara;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Sekine, Ikuo;
Kunitoh, Hideo;
Ohe, Yuichiro;
Ohki, Emiko;
Hashimoto, Junichi;
Tamura, Tomohide

Publication type:

Article

Bodyweight change during the first 5 days of chemotherapy as an indicator of cisplatin renal toxicity.

Published in:

Cancer Science, 2007, v. 98, n. 9, p. 1408, doi. 10.1111/j.1349-7006.2007.00532.x

By:

Sekine, Ikuo;
Yamada, Kazuhiko;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Kunitoh, Hideo;
Ohe, Yuichiro;
Tamura, Tomohide

Publication type:

Article

Phase I study of the second-generation, recombinant, human EGFR antibody necitumumab in Japanese patients with advanced solid tumors.

Published in:

2016

By:

Tamura, Yosuke;
Nokihara, Hiroshi;
Honda, Kazunori;
Tanabe, Yuko;
Asahina, Hajime;
Yamada, Yasuhide;
Enatsu, Sotaro;
Kurek, Raffael;
Yamamoto, Noboru;
Tamura, Tomohide

Publication type:

journal article

Phase 1 study of galunisertib, a TGF-beta receptor I kinase inhibitor, in Japanese patients with advanced solid tumors.

Published in:

2015

By:

Fujiwara, Yutaka;
Nokihara, Hiroshi;
Yamada, Yasuhide;
Yamamoto, Noboru;
Sunami, Kuniko;
Utsumi, Hirofumi;
Asou, Hiroya;
TakahashI, Osamu;
Ogasawara, Ken;
Gueorguieva, Ivelina;
Tamura, Tomohide

Publication type:

journal article

A phase 1 study of lenvatinib, multiple receptor tyrosine kinase inhibitor, in Japanese patients with advanced solid tumors.

Published in:

2015

By:

Nakamichi, Shinji;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Yamada, Yasuhide;
Honda, Kazunori;
Tamura, Yosuke;
Wakui, Hiroshi;
Sasaki, Tatsuya;
Yusa, Wataru;
Fujino, Katsuki;
Tamura, Tomohide

Publication type:

journal article

A phase 1 study evaluating the pharmacokinetics and preliminary efficacy of veliparib (ABT-888) in combination with carboplatin/paclitaxel in Japanese subjects with non-small cell lung cancer (NSCLC).

Published in:

2015

By:

Mizugaki, Hidenori;
Yamamoto, Noboru;
Nokihara, Hiroshi;
Fujiwara, Yutaka;
Horinouchi, Hidehito;
Kanda, Shintaro;
Kitazono, Satoru;
Yagishita, Shigehiro;
Xiong, Hao;
Qian, Jane;
Hashiba, Hideyuki;
Shepherd, Stacie;
Giranda, Vincent;
Tamura, Tomohide;
Shepherd, Stacie P

Publication type:

journal article

Comparison of the pharmacokinetics of erlotinib administered in complete fasting and 2 h after a meal in patients with lung cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 76, n. 1, p. 125, doi. 10.1007/s00280-015-2778-8

By:

Katsuya, Yuki;
Fujiwara, Yutaka;
Sunami, Kuniko;
Utsumi, Hirofumi;
Goto, Yasushi;
Kanda, Shintaro;
Horinouchi, Hidehito;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Takashima, Yuki;
Osawa, Satoko;
Ohe, Yuichiro;
Tamura, Tomohide;
Hamada, Akinobu

Publication type:

Article

A phase I study of resminostat in Japanese patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 6, p. 1155, doi. 10.1007/s00280-015-2741-8

By:

Kitazono, Satoru;
Fujiwara, Yutaka;
Nakamichi, Shinji;
Mizugaki, Hidenori;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Yamada, Yasuhide;
Inukai, Eri;
Nakamura, Osamu;
Tamura, Tomohide

Publication type:

Article

A phase 1 study of linifanib in combination with carboplatin/paclitaxel as first-line treatment of Japanese patients with advanced or metastatic non-small cell lung cancer (NSCLC).

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 1, p. 37, doi. 10.1007/s00280-014-2478-9

By:

Horinouchi, Hidehito;
Yamamoto, Noboru;
Nokihara, Hiroshi;
Horai, Takeshi;
Nishio, Makoto;
Ohyanagi, Fumiyoshi;
Horiike, Atsushi;
Nakagawa, Kazuhiko;
Terashima, Masaaki;
Okabe, Takafumi;
Kaneda, Hiroyasu;
McKee, Mark;
Carlson, Dawn;
Xiong, Hao;
Tamura, Tomohide

Publication type:

Article

A phase 1 study of linifanib in combination with carboplatin/paclitaxel as first-line treatment of Japanese patients with advanced or metastatic non-small cell lung cancer (NSCLC).

Published in:

2014

By:

Horinouchi, Hidehito;
Yamamoto, Noboru;
Nokihara, Hiroshi;
Horai, Takeshi;
Nishio, Makoto;
Ohyanagi, Fumiyoshi;
Horiike, Atsushi;
Nakagawa, Kazuhiko;
Terashima, Masaaki;
Okabe, Takafumi;
Kaneda, Hiroyasu;
McKee, Mark D;
Carlson, Dawn M;
Xiong, Hao;
Tamura, Tomohide

Publication type:

journal article

A phase 1 and dose-finding study of LY2523355 (litronesib), an Eg5 inhibitor, in Japanese patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 1, p. 15, doi. 10.1007/s00280-014-2467-z

By:

Wakui, Hiroshi;
Yamamoto, Noboru;
Kitazono, Satoru;
Mizugaki, Hidenori;
Nakamichi, Shinji;
Fujiwara, Yutaka;
Nokihara, Hiroshi;
Yamada, Yasuhide;
Suzuki, Kohei;
Kanda, Hironori;
Akinaga, Shiro;
Tamura, Tomohide

Publication type:

Article

Phase 1 and dose-finding study of patritumab (U3-1287), a human monoclonal antibody targeting HER3, in Japanese patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 73, n. 3, p. 511, doi. 10.1007/s00280-014-2375-2

By:

Wakui, Hiroshi;
Yamamoto, Noboru;
Nakamichi, Shinji;
Tamura, Yousuke;
Nokihara, Hiroshi;
Yamada, Yasuhide;
Tamura, Tomohide

Publication type:

Article

Phase I and pharmacokinetic/pharmacodynamic study of RO5126766, a first-in-class dual Raf/MEK inhibitor, in Japanese patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 72, n. 3, p. 577, doi. 10.1007/s00280-013-2228-4

By:

Honda, Kazunori;
Yamamoto, Noboru;
Nokihara, Hiroshi;
Tamura, Yosuke;
Asahina, Hajime;
Yamada, Yasuhide;
Suzuki, Shigenobu;
Yamazaki, Naoya;
Ogita, Yoshitaka;
Tamura, Tomohide

Publication type:

Article

Phase I study of oral gemcitabine prodrug (LY2334737) in Japanese patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 6, p. 1645, doi. 10.1007/s00280-013-2165-2

By:

Yamamoto, Noboru;
Nokihara, Hiroshi;
Yamada, Yasuhide;
Uenaka, Kazunori;
Sekiguchi, Risa;
Makiuchi, Takeshi;
Slapak, Christopher;
Benhadji, Karim;
Tamura, Tomohide

Publication type:

Article

A phase I study of BMS-690514 in Japanese patients with advanced or metastatic solid tumors.

Published in:

2012

By:

Nokihara H;
Yamamoto N;
Yamada Y;
Yamada K;
Hirata T;
Goto Y;
Tanioka M;
Ikeda Y;
Tamura T;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Yamada, Yasuhide;
Yamada, Kazuhiko;
Hirata, Taizo;
Goto, Yasushi;
Tanioka, Maki;
Ikeda, Yoko;
Tamura, Tomohide

Publication type:

journal article

A phase I study of BMS-690514 in Japanese patients with advanced or metastatic solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 70, n. 4, p. 559, doi. 10.1007/s00280-012-1932-9

By:

Nokihara, Hiroshi;
Yamamoto, Noboru;
Yamada, Yasuhide;
Yamada, Kazuhiko;
Hirata, Taizo;
Goto, Yasushi;
Tanioka, Maki;
Ikeda, Yoko;
Tamura, Tomohide

Publication type:

Article

An open-label, phase 1 study evaluating safety, tolerability, and pharmacokinetics of linifanib (ABT-869) in Japanese patients with solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1477, doi. 10.1007/s00280-012-1846-6

By:

Asahina, Hajime;
Tamura, Yosuke;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Seki, Yoshitaka;
Shibata, Takashi;
Goto, Yasushi;
Tanioka, Maki;
Yamada, Yasuhide;
Coates, Andrew;
Chiu, Yi-Lin;
Li, Xiaohui;
Pradhan, Rajendra;
Ansell, Peter;
McKeegan, Evelyn;
McKee, Mark;
Carlson, Dawn;
Tamura, Tomohide

Publication type:

Article

Pharmacokinetic and pharmacodynamic study on amrubicin and amrubicinol in Japanese patients with lung cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 4, p. 861, doi. 10.1007/s00280-011-1768-8

By:

Makino, Yoshinori;
Yamamoto, Noboru;
Sato, Hitoshi;
Ando, Reiko;
Goto, Yasushi;
Tanai, Chiharu;
Asahina, Hajime;
Nokihara, Hiroshi;
Sekine, Ikuo;
Kunitoh, Hideo;
Ohe, Yuichiro;
Sugiyama, Erika;
Yokote, Nobuaki;
Tamura, Tomohide;
Yamamoto, Hiroshi

Publication type:

Article

Phase I study for ridaforolimus, an oral mTOR inhibitor, in Japanese patients with advanced solid tumors.

Published in:

2012

By:

Seki, Yoshitaka;
Yamamoto, Noboru;
Tamura, Yosuke;
Goto, Yasushi;
Shibata, Takashi;
Tanioka, Maki;
Asahina, Hajime;
Nokihara, Hiroshi;
Yamada, Yasuhide;
Shimamoto, Takashi;
Noguchi, Kazuo;
Tamura, Tomohide

Publication type:

Report

Phase I, dose escalation and pharmacokinetic study of cediranib (RECENTIN™), a highly potent and selective VEGFR signaling inhibitor, in Japanese patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2009, v. 64, n. 6, p. 1165, doi. 10.1007/s00280-009-0979-8

By:

Yamamoto, Noboru;
Tamura, Tomohide;
Yamamoto, Nobuyuki;
Yamada, Kazuhiko;
Yamada, Yasuhide;
Nokihara, Hiroshi;
Fujiwara, Yutaka;
Takahashi, Toshiaki;
Murakami, Haruyasu;
Boku, Narikazu;
Yamazaki, Kentaro;
Puchalski, Thomas A.;
Shin, Eisei

Publication type:

Article