Works by Nizet, Victor

Results: 270

Group B Streptococci lyse endothelial cells to infect the brain in a zebrafish meningitis model.

Published in:

PLoS Biology, 2025, v. 23, n. 7, p. 1, doi. 10.1371/journal.pbio.3003236

By:

Ravishankar, Sumedha;
Tuohey, Samantha M.;
Ramos, Nicole O.;
Uchiyama, Satoshi;
Hayes, Megan I.;
Kang, Kalisa;
Nizet, Victor;
Madigan, Cressida A.

Publication type:

Article

RAB11-mediated trafficking in host-pathogen interactions.

Published in:

Nature Reviews Microbiology, 2014, v. 12, n. 9, p. 624, doi. 10.1038/nrmicro3325

By:

Guichard, Annabel;
Nizet, Victor;
Bier, Ethan

Publication type:

Article

Molecular insight into invasive group A streptococcal disease.

Published in:

Nature Reviews Microbiology, 2011, v. 9, n. 10, p. 724, doi. 10.1038/nrmicro2648

By:

Cole, Jason N.;
Barnett, Timothy C.;
Nizet, Victor;
Walker, Mark J.

Publication type:

Article

Tuning the Innate Immune Response to Cyclic Dinucleotides by Using Atomic Mutagenesis.

Published in:

ChemBioChem, 2020, v. 21, n. 18, p. 2595, doi. 10.1002/cbic.202000162

By:

Li, Yao;
Fin, Andrea;
Rovira, Alexander R.;
Su, Yichi;
Dippel, Andrew B.;
Valderrama, Jonathan Andrés;
Riestra, Angelica M.;
Nizet, Victor;
Hammond, Ming C.;
Tor, Yitzhak

Publication type:

Article

Salinipyrone and Pacificanone Are Biosynthetic Byproducts of the Rosamicin Polyketide Synthase.

Published in:

ChemBioChem, 2015, v. 16, n. 10, p. 1443, doi. 10.1002/cbic.201500177

By:

Awakawa, Takayoshi;
Crüsemann, Max;
Munguia, Jason;
Ziemert, Nadine;
Nizet, Victor;
Fenical, William;
Moore, Bradley S.

Publication type:

Article

The interplay between Siglecs and sialylated pathogens.

Published in:

Glycobiology, 2014, v. 24, n. 9, p. 818, doi. 10.1093/glycob/cwu067

By:

Chang, Yung-Chi;
Nizet, Victor

Publication type:

Article

Genetic and biochemical modulation of sialic acid O-acetylation on group B Streptococcus: Phenotypic and functional impact.

Published in:

Glycobiology, 2009, v. 19, n. 11, p. 1204, doi. 10.1093/glycob/cwp111

By:

Weiman, Shannon;
Dahesh, Samira;
Carlin, Aaron F.;
Varki, Ajit;
Nizet, Victor;
Lewis, Amanda L.

Publication type:

Article

IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ.

Published in:

Nature Immunology, 2011, v. 12, n. 2, p. 144, doi. 10.1038/ni.1976

By:

Hsu, Li-Chung;
Enzler, Thomas;
Seita, Jun;
Timmer, Anjuli M;
Lee, Chih-Yuan;
Lai, Ting-Yu;
Yu, Guann-Yi;
Lai, Liang-Chuan;
Temkin, Vladislav;
Sinzig, Ursula;
Aung, Thiha;
Nizet, Victor;
Weissman, Irving L;
Karin, Michael

Publication type:

Article

Identifying the effect of vancomycin on health care–associated methicillin-resistant Staphylococcus aureus strains using bacteriological and physiological media.

Published in:

GigaScience, 2021, v. 10, n. 1, p. 1, doi. 10.1093/gigascience/giaa156

By:

Rajput, Akanksha;
Poudel, Saugat;
Tsunemoto, Hannah;
Meehan, Michael;
Szubin, Richard;
Olson, Connor A;
Seif, Yara;
Lamsa, Anne;
Dillon, Nicholas;
Vrbanac, Alison;
Sugie, Joseph;
Dahesh, Samira;
Monk, Jonathan M;
Dorrestein, Pieter C;
Knight, Rob;
Pogliano, Joe;
Nizet, Victor;
Feist, Adam M;
Palsson, Bernhard O

Publication type:

Article

A Red Blood Cell Membrane-Camouflaged Nanoparticle Counteracts Streptolysin O-Mediated Virulence Phenotypes of Invasive Group A Streptococcus.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00477

By:

Escajadillo, Tamara;
Olson, Joshua;
Luk, Brian T.;
Liangfang Zhang;
Nizet, Victor

Publication type:

Article

Pathogen Microevolution in High Resolution.

Published in:

Science Translational Medicine, 2010, v. 2, n. 16, p. 1, doi. 10.1126/scitranslmed.3000713

By:

Aziz, Ramy K.;
Nizet, Victor

Publication type:

Article

Hypoxia-Inducible Factor 1 Alpha Is Dispensable for Host Defense of Group B Streptococcus Colonization and Infection.

Published in:

Journal of Innate Immunity, 2021, v. 13, n. 6, p. 391, doi. 10.1159/000515739

By:

Lum, Gregory R.;
Mercado, Vicki;
van Ens, Diede;
Nizet, Victor;
Kimmey, Jacqueline M.;
Patras, Kathryn A.

Publication type:

Article

Siglec-14 Enhances NLRP3-Inflammasome Activation in Macrophages.

Published in:

Journal of Innate Immunity, 2020, v. 12, n. 4, p. 333, doi. 10.1159/000504323

By:

Tsai, Chih-Ming;
Riestra, Angelica M.;
Ali, Syed Raza;
Fong, Jerry J.;
Liu, Janet Z.;
Hughes, Gillian;
Varki, Ajit;
Nizet, Victor

Publication type:

Article

Augmentation of Urinary Lactoferrin Enhances Host Innate Immune Clearance of Uropathogenic Escherichia coli.

Published in:

Journal of Innate Immunity, 2019, v. 11, n. 6, p. 481, doi. 10.1159/000499342

By:

Patras, Kathryn A.;
Ha, Albert D.;
Rooholfada, Emma;
Olson, Joshua;
Ramachandra Rao, Satish P.;
Lin, Ann E.;
Nizet, Victor

Publication type:

Article

Trichomonas vaginalis Induces NLRP3 Inflammasome Activation and Pyroptotic Cell Death in Human Macrophages.

Published in:

Journal of Innate Immunity, 2019, v. 11, n. 1, p. 86, doi. 10.1159/000493585

By:

Riestra, Angelica Montenegro;
Valderrama, J. Andrés;
Patras, Kathryn A.;
Booth, Sharon D.;
Quek, Xing Yen;
Tsai, Chih-Ming;
Nizet, Victor

Publication type:

Article

Novel Role of the Antimicrobial Peptide LL-37 in the Protection of Neutrophil Extracellular Traps against Degradation by Bacterial Nucleases.

Published in:

Journal of Innate Immunity, 2014, v. 6, n. 6, p. 860, doi. 10.1159/000363699

By:

Neumann, ariane;
Völlger, Lena;
Berends, Evelien T.M.;
Molhoek, E. Margo;
Stapels, Daphne a.C.;
Midon, Marika;
Friães, ana;
Pingoud, alfred;
Rooijakkers, Suzan H.M.;
Gallo, Richard L.;
Mörgelin, Matthias;
Nizet, Victor;
Naim, Hassan Y.;
von Köckritz-Blickwede, Maren

Publication type:

Article

A Staphylococcus aureus TIR Domain Protein Virulence Factor Blocks TLR2-Mediated NF-κB Signaling.

Published in:

Journal of Innate Immunity, 2014, v. 6, n. 4, p. 485, doi. 10.1159/000357618

By:

askarian, Fatemeh;
van Sorge, Nina M.;
Sangvik, Maria;
Beasley, Federico C.;
Henriksen, Jørn R.;
Sollid, Johanna U.E.;
van Strijp, Jos a.G.;
Nizet, Victor;
Johannessen, Mona

Publication type:

Article

Plasmin(ogen) Acquisition by Group A Streptococcus Protects against C3b-Mediated Neutrophil Killing.

Published in:

Journal of Innate Immunity, 2014, v. 6, n. 2, p. 240, doi. 10.1159/000353754

By:

Ly, Diane;
Taylor, Jude M.;
Tsatsaronis, James a.;
Monteleone, Mercedes M.;
Skora, amanda S.;
Donald, Cortny a.;
Maddocks, Tracy;
Nizet, Victor;
West, Nicholas P.;
Ranson, Marie;
Walker, Mark J.;
Mcarthur, Jason D.;
Sanderson-Smith, Martina L.

Publication type:

Article

Staphylococcus aureus Virulence Is Enhanced by Secreted Factors That Block Innate Immune Defenses.

Published in:

Journal of Innate Immunity, 2012, v. 4, n. 3, p. 301, doi. 10.1159/000334604

By:

Jongerius, Ilse;
von Köckritz-Blickwede, Maren;
Horsburgh, Malcolm J.;
Ruyken, Maartje;
Nizet, Victor;
Rooijakkers, Suzan H.M.

Publication type:

Article

Importance of Toll-Like Receptor 9 in Host Defense against M1T1 Group A Streptococcus Infections.

Published in:

Journal of Innate Immunity, 2012, v. 4, n. 2, p. 213, doi. 10.1159/000329550

By:

Zinkernagel, Annelies S.;
Hruz, Petr;
Uchiyama, Satoshi;
von Köckritz-Blickwede, Maren;
Schuepbach, Reto A.;
Hayashi, Tomoko;
Carson, Dennis A.;
Nizet, Victor

Publication type:

Article

Bacteria and Phagocytes: Mortal Enemies.

Published in:

Journal of Innate Immunity, 2010, v. 2, n. 6, p. 505, doi. 10.1159/000320473

By:

Nizet, Victor

Publication type:

Article

Nuclease Expression by Staphylococcus aureus Facilitates Escape from Neutrophil Extracellular Traps.

Published in:

Journal of Innate Immunity, 2010, v. 2, n. 6, p. 576, doi. 10.1159/000319909

By:

Berends, Evelien T.M.;
Horswill, Alexander R.;
Haste, Nina M.;
Monestier, Marc;
Nizet, Victor;
von Köckritz-Blickwede, Maren

Publication type:

Article

Streptococcal Inhibitor of Complement Promotes Innate Immune Resistance Phenotypes of Invasive M1T1 Group A Streptococcus.

Published in:

Journal of Innate Immunity, 2010, v. 2, n. 6, p. 587, doi. 10.1159/000317672

By:

Pence, Morgan A.;
Rooijakkers, Suzan H.M.;
Cogen, Anna L.;
Cole, Jason N.;
Hollands, Andrew;
Gallo, Richard L.;
Nizet, Victor

Publication type:

Article

Parameters Governing Invasive Disease Propensity of Non-M1 Serotype Group A Streptococci.

Published in:

Journal of Innate Immunity, 2010, v. 2, n. 6, p. 596, doi. 10.1159/000317640

By:

Maamary, Peter G.;
Sanderson-Smith, Martina L.;
Aziz, Ramy K.;
Hollands, Andrew;
Cole, Jason N.;
McKay, Fiona C.;
McArthur, Jason D.;
Kirk, Joshua K.;
Cork, Amanda J.;
Keefe, Rachael J.;
Kansal, Rita G.;
Sun, Hongmin;
Taylor, William L.;
Chhatwal, Gursharan S.;
Ginsburg, David;
Nizet, Victor;
Kotb, Malak;
Walker, Mark J.

Publication type:

Article

ClpX Contributes to Innate Defense Peptide Resistance and Virulence Phenotypes of Bacillus anthracis.

Published in:

Journal of Innate Immunity, 2009, v. 1, n. 5, p. 494, doi. 10.1159/000225955

By:

McGillivray, Shauna M.;
Ebrahimi, Celia M.;
Fisher, Nathan;
Sabet, Mojgan;
Zhang, Dawn X.;
Chen, Yahua;
Haste, Nina M.;
Aroian, Raffi V.;
Gallo, Richard L.;
Guiney, Donald G.;
Friedlander, Arthur M.;
Koehler, Theresa M.;
Nizet, Victor

Publication type:

Article

M1 Protein Allows Group A Streptococcal Survival in Phagocyte Extracellular Traps through Cathelicidin Inhibition.

Published in:

Journal of Innate Immunity, 2009, v. 1, n. 3, p. 202, doi. 10.1159/000203645

By:

Lauth, Xavier;
von Köckritz-Blickwede, Maren;
McNamara, Case W.;
Myskowski, Sandra;
Zinkernagel, Annelies S.;
Beall, Bernard;
Ghosh, Partho;
Gallo, Richard L.;
Nizet, Victor

Publication type:

Article

M proteins of group A Streptococcus bind hyaluronic acid via arginine–arginine/serine–arginine motifs.

Published in:

FASEB Journal, 2024, v. 38, n. 20, p. 1, doi. 10.1096/fj.202401301R

By:

McEwan, Tahnee B.‐D.;
De Oliveira, David M. P.;
Stares, Emily K.;
Hartley‐Tassell, Lauren E.;
Day, Christopher J.;
Proctor, Emma‐Jayne;
Nizet, Victor;
Walker, Mark J.;
Jennings, Michael P.;
Sluyter, Ronald;
Sanderson‐Smith, Martina L.

Publication type:

Article

Evaluation of Small Molecule Inhibitors of Pseudomonas Virulence factor LasB as Non‐Traditional Immunotherapeutics.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R3074

By:

Chou, Sophia R.;
LaRock, Doris L.;
Sun, Joshua;
Nizet, Victor;
Bohannon, Julia K.;
LaRock, Christopher N.

Publication type:

Article

Evasion of Neutrophil Extracellular Traps by Respiratory Pathogens.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2017, v. 56, n. 4, p. 423, doi. 10.1165/rcmb.2016-0193PS

By:

Storisteanu, Daniel M. L.;
Pocock, Joanna M.;
Cowburn, Andrew S.;
Juss, Jatinder K.;
Nadesalingam, Angalee;
Nizet, Victor;
Chilvers, Edwin R.

Publication type:

Article

Strengthening of enterococcal biofilms by Esp.

Published in:

PLoS Pathogens, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.ppat.1010829

By:

Spiegelman, Lindsey;
Bahn-Suh, Adrian;
Montaño, Elizabeth T.;
Zhang, Ling;
Hura, Greg L.;
Patras, Kathryn A.;
Kumar, Amit;
Tezcan, F. Akif;
Nizet, Victor;
Tsutakawa, Susan E.;
Ghosh, Partho

Publication type:

Article

Transfer of antibiotics and their metabolites in human milk: Implications for infant health and microbiota.

Published in:

Pharmacotherapy, 2023, v. 43, n. 5, p. 442, doi. 10.1002/phar.2732

By:

Thomas, Sydney P.;
Denizer, Erce;
Zuffa, Simone;
Best, Brookie M.;
Bode, Lars;
Chambers, Christina D.;
Dorrestein, Pieter C.;
Liu, George Y.;
Momper, Jeremiah D.;
Nizet, Victor;
Tsunoda, Shirley M.;
Tremoulet, Adriana H.

Publication type:

Article

Role of group A Streptococcus HtrA in the maturation of SpeB protease.

Published in:

Proteomics, 2007, v. 7, n. 24, p. 4488, doi. 10.1002/pmic.200700626

By:

Cole, Jason N.;
Aquilina, John A.;
Hains, Peter G.;
Henningham, Anna;
Sriprakash, Kadaba S.;
Caparon, Michael G.;
Nizet, Victor;
Kotb, Malak;
Cordwell, Stuart J.;
Djordjevic, Steven P.;
Walker, Mark J.

Publication type:

Article

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α.

Published in:

2008

By:

Rius, Jordi;
Guma, Monica;
Schachtrup, Christian;
Akassoglou, Katerina;
Zinkernagel, Annelies S.;
Nizet, Victor;
Johnson, Randall S.;
Haddad, Gabriel G.;
Karin, Michael

Publication type:

Letter

IKKalimits macrophage NF-?B activation and contributes to the resolution of inflammation.

Published in:

Nature, 2005, v. 434, n. 7037, p. 1138, doi. 10.1038/nature03491

By:

Lawrence, Toby;
Bebien, Magali;
Liu, George Y.;
Nizet, Victor;
Karin, Michael

Publication type:

Article

Environmental conditions dictate differential evolution of vancomycin resistance in Staphylococcus aureus.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02339-z

By:

Machado, Henrique;
Seif, Yara;
Sakoulas, George;
Olson, Connor A.;
Hefner, Ying;
Anand, Amitesh;
Jones, Ying Z.;
Szubin, Richard;
Palsson, Bernhard O.;
Nizet, Victor;
Feist, Adam M.

Publication type:

Article

Functional and Proteomic Analysis of Streptococcus pyogenes Virulence Upon Loss of Its Native Cas9 Nuclease.

Published in:

Frontiers in Microbiology, 2019, p. 1, doi. 10.3389/fmicb.2019.01967

By:

Gao, Nina J.;
Al-Bassam, Mahmoud M.;
Poudel, Saugat;
Wozniak, Jacob M.;
Gonzalez, David J.;
Olson, Joshua;
Zengler, Karsten;
Nizet, Victor;
Valderrama, J. Andrés

Publication type:

Article

Streptolysin O Rapidly Impairs Neutrophil Oxidative Burst and Antibacterial Responses to Group A Streptococcus.

Published in:

Frontiers in Immunology, 2015, v. 6, p. 1, doi. 10.3389/fimmu.2015.00581

By:

Satoshi Uchiyama;
Döhrmann, Simon;
Timmer, Anjuli M.;
Dixit, Neha;
Ghochani, Mariam;
Bhandari, Tamara;
Timmer, John C.;
Sprague, Kimberly;
Bubeck-Wardenburg, Juliane;
Simon, Scott I.;
Nizet, Victor;
Alonzo, Francis;
Beres, Stephen B.

Publication type:

Article

Inflammasome/IL-1β responses to streptococcal pathogens.

Published in:

Frontiers in Immunology, 2015, v. 6, p. 1, doi. 10.3389/fimmu.2015.00518

By:

LaRock, Christopher N.;
Nizet, Victor

Publication type:

Article

Editorial: Host-Pathogen Interactions During Pneumococcal Infection.

Published in:

2021

By:

Yamaguchi, Masaya;
Kinjo, Yuki;
Nizet, Victor

Publication type:

Editorial

Serum opacity factor promotes group A streptococcal epithelial cell invasion and virulence.

Published in:

Molecular Microbiology, 2006, v. 62, n. 1, p. 15, doi. 10.1111/j.1365-2958.2006.05337.x

By:

Timmer, Anjuli M.;
Kristian, Sascha A.;
Datta, Vivekanand;
Jeng, Arthur;
Gillen, Christine M.;
Walker, Mark J.;
Beall, Bernard;
Nizet, Victor

Publication type:

Article

Mutational analysis of the group A streptococcal operon encoding streptolysin S and its virulence role in invasive infection.

Published in:

Molecular Microbiology, 2005, v. 56, n. 3, p. 681, doi. 10.1111/j.1365-2958.2005.04583.x

By:

Datta, Vivekanand;
Myskowski, Sandra M.;
Kwinn, Laura A.;
Chiem, Daniel N.;
Varki, Nissi;
Kansal, Rita G.;
Kotb, Malak;
Nizet, Victor

Publication type:

Article

Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB.

Published in:

Molecular Microbiology, 2004, v. 51, n. 1, p. 123, doi. 10.1046/j.1365-2958.2003.03797.x

By:

Aziz, Ramy K.;
Pabst, Michael J.;
Jeng, Arthur;
Kansal, Rita;
Low, Donald E.;
Nizet, Victor;
Kotb, Malak

Publication type:

Article

Genetic basis for the β-haemolytic/cytolytic activity of group B Streptococcus.

Published in:

Molecular Microbiology, 2001, v. 39, n. 2, p. 236, doi. 10.1046/j.1365-2958.2001.02211.x

By:

Pritzlaff, Craig A.;
Chang, Jennifer C. W.;
Kuo, Shrin P.;
Tamura, Glen S.;
Rubens, Craig E.;
Nizet, Victor

Publication type:

Article

Bacterial Phenotype Variants in Group B Streptococcal Toxic Shock Syndrome.

Published in:

Emerging Infectious Diseases, 2009, v. 15, n. 2, p. 223, doi. 10.3201/eid1502.080990

By:

Sendi, Parham;
Johansson, Linda;
Dahesh, Samira;
Van Sorge, Nina M.;
Darenberg, Jessica;
Norgren, Mari;
Sjölin, Jan;
Nizet, Victor;
Norrby-Teglund, Anna

Publication type:

Article

Iron-chelating agent desferrioxamine stimulates formation of neutrophil extracellular traps (NETs) in human blood-derived neutrophils.

Published in:

Bioscience Reports, 2016, v. 36, n. 3, p. 1, doi. 10.1042/BSR20160031

By:

Völlger, Lena;
Akong-Moore, Kathryn;
Cox, Linda;
Goldmann, Oliver;
Yanming Wang;
Schäfer, Simon T.;
Naim, Hassan Y.;
Nizet, Victor;
Köckritz-Blickwede, Maren von

Publication type:

Article

Current Paradigms of Combination Therapy in Methicillin-Resistant Staphylococcus aureus (MRSA) Bacteremia: Does it Work, Which Combination, and For Which Patients?

Published in:

Clinical Infectious Diseases, 2021, v. 73, n. 12, p. 2353, doi. 10.1093/cid/ciab452

By:

Rose, Warren;
Fantl, Michael;
Geriak, Matthew;
Nizet, Victor;
Sakoulas, George

Publication type:

Article

Cefazolin and Ertapenem Salvage Therapy Rapidly Clears Persistent Methicillin-Susceptible Staphylococcus aureus Bacteremia.

Published in:

Clinical Infectious Diseases, 2020, v. 71, n. 6, p. 1413, doi. 10.1093/cid/ciz995

By:

Ulloa, Erlinda R;
Singh, Kavindra V;
Geriak, Matthew;
Haddad, Fadi;
Murray, Barbara E;
Nizet, Victor;
Sakoulas, George

Publication type:

Article

Interleukin (IL)-1β and IL-10 Host Responses in Patients With Staphylococcus aureus Bacteremia Determined by Antimicrobial Therapy.

Published in:

Clinical Infectious Diseases, 2020, v. 70, n. 12, p. 2634, doi. 10.1093/cid/ciz686

By:

Volk, Cecilia F;
Burgdorf, Sarah;
Edwardson, Graham;
Nizet, Victor;
Sakoulas, George;
Rose, Warren E

Publication type:

Article

Neutrophil Extracellular Traps: An Emerging Therapeutic Target to Improve Infectious Disease Outcomes.

Published in:

Journal of Infectious Diseases, 2024, v. 230, n. 2, p. 514, doi. 10.1093/infdis/jiae252

By:

Meier, Angela;
Sakoulas, George;
Nizet, Victor;
Ulloa, Erlinda R

Publication type:

Article

Study of the IgG endoglycosidase EndoS in group A streptococcal phagocyte resistance and virulence.

Published in:

BMC Microbiology, 2011, v. 11, n. 1, p. 120, doi. 10.1186/1471-2180-11-120

By:

Sjögren, Jonathan;
Okumura, Cheryl Y. M.;
Collin, Mattias;
Nizet, Victor;
Hollands, Andrew

Publication type:

Article