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Autophagy–lysosomal-associated neuronal death in neurodegenerative disease.
- Published in:
- Acta Neuropathologica, 2024, v. 148, n. 1, p. 1, doi. 10.1007/s00401-024-02799-7
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- Article
A 'Protease Activation Cascade' in the Pathogenesis of Alzheimer's Disease.
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- Annals of the New York Academy of Sciences, 2000, v. 924, n. 1, p. 117, doi. 10.1111/j.1749-6632.2000.tb05570.x
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- Article
Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors.
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- Translational Psychiatry, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41398-018-0194-7
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- Publication type:
- Article
Regional Selectivity of rab5 and rab7 Protein Upregulation in Mild Cognitive Impairment and Alzheimer's Disease.
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- Journal of Alzheimer's Disease, 2010, v. 22, n. 2, p. 631, doi. 10.3233/JAD-2010-101080
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- Article
Complexes of amyloid-beta and cystatin C in the human central nervous system.
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- 2009
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- Publication type:
- journal article
Complexes of Amyloid-β and Cystatin C in the Human Central Nervous System.
- Published in:
- Journal of Alzheimer's Disease, 2009, v. 18, n. 2, p. 273, doi. 10.3233/JAD-2009-1147
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- Publication type:
- Article
A gene toolbox for monitoring autophagy transcription.
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- Cell Death & Disease, 2021, v. 12, n. 11, p. 1, doi. 10.1038/s41419-021-04121-9
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- Article
mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome formation, and mitophagy.
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- Cell Death & Disease, 2019, v. 10, n. 8, p. N.PAG, doi. 10.1038/s41419-019-1752-5
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- Publication type:
- Article
Peripherin Is a Subunit of Peripheral Nerve Neurofilaments: Implications for Differential Vulnerability of CNS and Peripheral Nervous System Axons.
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- Journal of Neuroscience, 2012, v. 32, n. 25, p. 8501, doi. 10.1523/JNEUROSCI.1081-12.2012
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- Publication type:
- Article
Sensory Network Dysfunction, Behavioral Impairments, and Their Reversibility in an Alzheimer's β-Amyloidosis Mouse Model.
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- Journal of Neuroscience, 2011, v. 31, n. 44, p. 15962, doi. 10.1523/JNEUROSCI.2085-11.2011
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- Publication type:
- Article
Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy.
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- Journal of Neuroscience, 2011, v. 31, n. 21, p. 7817, doi. 10.1523/JNEUROSCI.6412-10.2011
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- Publication type:
- Article
Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis.
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- Journal of Neuroscience, 2010, v. 30, n. 45, p. 14946, doi. 10.1523/JNEUROSCI.4305-10.2010
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- Publication type:
- Article
Olfactory Dysfunction Correlates with Amyloid-β Burden in an Alzheimer's Disease Mouse Model.
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- Journal of Neuroscience, 2010, v. 30, n. 2, p. 505, doi. 10.1523/JNEUROSCI.4622-09.2010
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- Article
Neurofilaments Form a Highly Stable Stationary Cytoskeleton after Reaching a Critical Level in Axons.
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- Journal of Neuroscience, 2009, v. 29, n. 36, p. 11316, doi. 10.1523/JNEUROSCI.1942-09.2009
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- Publication type:
- Article
Anesthesia-Induced Hyperphosphorylation Detaches 3-Repeat Tau from Microtubules without Affecting Their Stability In Vivo.
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- Journal of Neuroscience, 2008, v. 28, n. 48, p. 12798, doi. 10.1523/JNEUROSCI.4101-08.2008
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- Publication type:
- Article
Marked Calpastatin (CAST) Depletion in Alzheimer's Disease Accelerates Cytoskeleton Disruption and Neurodegeneration: Neuroprotection by CAST Overexpression.
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- Journal of Neuroscience, 2008, v. 28, n. 47, p. 12241, doi. 10.1523/JNEUROSCI.4119-08.2008
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- Publication type:
- Article
Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease.
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- Journal of Neuroscience, 2008, v. 28, n. 27, p. 6926, doi. 10.1523/JNEUROSCI.0800-08.2008
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- Publication type:
- Article
Axonal Transport Rates In Vivo Are Unaffected by Tau Deletion or Overexpression in Mice.
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- Journal of Neuroscience, 2008, v. 28, n. 7, p. 1682, doi. 10.1523/JNEUROSCI.5242-07.2008
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- Publication type:
- Article
Amyloid precursor protein and endosomal-lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease.
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- FASEB Journal, 2017, v. 31, n. 7, p. 2729, doi. 10.1096/fj.201700359
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- Article
Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing.
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- FASEB Journal, 2010, v. 24, n. 8, p. 2783, doi. 10.1096/fj.09-146357
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- Publication type:
- Article
Age-dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model.
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- Journal of Neurochemistry, 2009, v. 110, n. 6, p. 1818, doi. 10.1111/j.1471-4159.2009.06277.x
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- Publication type:
- Article
Neurofilament tail phosphorylation: identity of the RT-97 phosphoepitope and regulation in neurons by cross-talk among proline-directed kinases.
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- Journal of Neurochemistry, 2008, v. 107, n. 1, p. 35, doi. 10.1111/j.1471-4159.2008.05547.x
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- Publication type:
- Article
Alzheimer’s presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo.
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- Journal of Neurochemistry, 2007, v. 102, n. 3, p. 619, doi. 10.1111/j.1471-4159.2007.04587.x
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- Publication type:
- Article
PHOSPHORYLATED TAIL DOMAINS OF NF-H and NF-M SUBUNITS TOGETHER REGULATE NEUROFILAMENT DENSITY BUT NOT THE RATE OF SLOW AXONAL TRANSPORT OF NEUROFILAMENTS IN OPTIC AXONS.
- Published in:
- Journal of Cancer Research & Therapeutics, 2007, v. 3, n. 3, p. 181
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- Publication type:
- Article
Macroautophagy -- a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease.
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- Journal of Cell Biology, 2005, v. 171, n. 1, p. 87, doi. 10.1083/jcb.200505082
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- Publication type:
- Article
The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament...
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- Journal of Cell Biology, 2003, v. 163, n. 5, p. 1021, doi. 10.1083/jcb.200308076
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- Publication type:
- Article
Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density.
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- Journal of Cell Biology, 2002, v. 159, n. 2, p. 279, doi. 10.1083/jcb.200205062
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- Article
Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport.
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- Journal of Cell Biology, 2002, v. 158, n. 4, p. 681, doi. 10.1083/jcb.200202037
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- Publication type:
- Article
Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice.
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- Human Molecular Genetics, 2014, v. 23, n. 15, p. 3975, doi. 10.1093/hmg/ddu112
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- Publication type:
- Article
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy.
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- Human Molecular Genetics, 2010, v. 19, n. 16, p. 3219, doi. 10.1093/hmg/ddq231
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- Publication type:
- Article
Lysosomal NEU1 deficiency affects amyloid precursor protein levels and amyloid-β secretion via deregulated lysosomal exocytosis.
- Published in:
- Nature Communications, 2013, v. 4, n. 11, p. 2734, doi. 10.1038/ncomms3734
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- Article
Triton-soluble phosphovariants of the heavy neurofilament subunit in developing and mature mouse central nervous system.
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- Journal of Neuroscience Research, 1997, v. 48, n. 6, p. 515, doi. 10.1002/(SICI)1097-4547(19970615)48:6<515::AID-JNR4>3.0.CO;2-D
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- Article
Correction: Drug development targeting degeneration of the basal forebrain cholinergic system: its time has come.
- Published in:
- 2023
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- Correction Notice
Drug development targeting degeneration of the basal forebrain cholinergic system: its time has come.
- Published in:
- Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00663-y
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- Publication type:
- Article
Lysosome and calcium dysregulation in Alzheimer's disease: partners in crime.
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- Biochemical Society Transactions, 2013, v. 41, n. 6, p. 1495, doi. 10.1042/BST20130201
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- Article
Neurofilaments: neurobiological foundations for biomarker applications.
- Published in:
- 2020
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- Publication type:
- journal article
Mechanisms of Neural and Behavioral Dysfunction in Alzheimer's Disease.
- Published in:
- Molecular Neurobiology, 2011, v. 43, n. 3, p. 163, doi. 10.1007/s12035-011-8177-1
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- Publication type:
- Article
Visualization of β-amyloid plaques in a transgenic mouse model of Alzheimer's disease using MR microscopy without contrast reagents.
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- Magnetic Resonance in Medicine, 2004, v. 52, n. 3, p. 538, doi. 10.1002/mrm.20196
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- Publication type:
- Article
MRI assessment of neuropathology in a transgenic mouse model of Alzheimer's disease.
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- Magnetic Resonance in Medicine, 2004, v. 51, n. 4, p. 794, doi. 10.1002/mrm.20038
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- Publication type:
- Article
Calpain activation in neurodegenerative diseases: confocal immunofluorescence study with antibodies specifically recognizing the active form of calpain 2.
- Published in:
- Acta Neuropathologica, 2002, v. 104, n. 1, p. 92, doi. 10.1007/s00401-002-0528-6
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- Publication type:
- Article
Dynamic behavior and organization of cytoskeletal proteins in neurons: Reconciling old and new...
- Published in:
- BioEssays, 1998, v. 20, n. 10, p. 798, doi. 10.1002/(SICI)1521-1878(199810)20:10<798::AID-BIES5>3.0.CO;2-7
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- Publication type:
- Article
Quinine sulfate for pain in the guillain-barré syndrome.
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- Annals of Neurology, 1978, v. 4, n. 4, p. 386, doi. 10.1002/ana.410040422
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- Publication type:
- Article
Cystatin C inhibits amyloid-β deposition in Alzheimer's disease mouse models.
- Published in:
- Nature Genetics, 2007, v. 39, n. 12, p. 1440, doi. 10.1038/ng.2007.29
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- Publication type:
- Article
Aging, gender and APOE isotype modulate metabolism of Alzheimer's Aβ peptides and F<sub>2</sub>-isoprostanes in the absence of detectable amyloid deposits.
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- Journal of Neurochemistry, 2004, v. 90, n. 4, p. 1011, doi. 10.1111/j.1471-4159.2004.02532.x
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- Publication type:
- Article
Co-expressed presenilin 1 NTF and CTF form functional γ-secretase complexes in cells devoid of full-length protein.
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- Journal of Neurochemistry, 2004, v. 89, n. 1, p. 44, doi. 10.1046/j.1471-4159.2003.02298.x
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- Publication type:
- Article
Serine-23 Is a Major Protein Kinase A Phosphorylation Site on the Amino-Terminal Head Domain of the Middle Molecular Mass Subunit of Neurofilament Proteins.
- Published in:
- Journal of Neurochemistry, 1999, v. 72, n. 2, p. 491, doi. 10.1046/j.1471-4159.1999.0720491.x
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- Publication type:
- Article
Cellular Expression and Proteolytic Processing of Presenilin Proteins Is Developmentally Regulated During Neuronal Differentiation.
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- Journal of Neurochemistry, 1997, v. 69, n. 6, p. 2432, doi. 10.1046/j.1471-4159.1997.69062432.x
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- Publication type:
- Article
Calcium Influx into Human Neuroblastoma Cells Induces ALZ-50 Immunoreactivity: Involvement of Calpain-Mediated Hydrolysis of Protein Kinase C.
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- Journal of Neurochemistry, 1996, v. 66, n. 4, p. 1539, doi. 10.1046/j.1471-4159.1996.66041539.x
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- Publication type:
- Article
Enhancement of Neurite Outgrowth Following Calpain Inhibition Is Mediated by Protein Kinase C.
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- Journal of Neurochemistry, 1995, v. 65, n. 2, p. 517, doi. 10.1046/j.1471-4159.1995.65020517.x
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- Publication type:
- Article
Purification and Properties of High Molecular Weight Calpastatin from Bovine Brain.
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- Journal of Neurochemistry, 1995, v. 64, n. 2, p. 859, doi. 10.1046/j.1471-4159.1995.64020859.x
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- Publication type:
- Article