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Results from the long‐term extension of PRIME: A randomized Phase 1b trial of aducanumab.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 5, p. 3406, doi. 10.1002/alz.13755
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- Article
White matter hyperintensity patterns: associations with comorbidities, amyloid, and cognition.
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- Alzheimer's Research & Therapy, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13195-024-01435-6
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- Article
Explaining variability in early stages of [18F]‐flortaucipir tau‐PET binding: Focus on sex differences.
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- Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2024, v. 16, n. 1, p. 1, doi. 10.1002/dad2.12565
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- Article
MRI reveals cerebral iron, calcification and spinal cord atrophy in M83 mouse model of Parkinson's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.070711
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- Article
Automatic analysis of skull thickness, scalp‐to‐cortex distance and association with age and sex in cognitively normal elderly.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.075312
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- Article
Automatic analysis of skull thickness, scalp‐to‐cortex distance and association with age and sex in cognitively normal elderly.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081676
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- Article
Early β‐amyloid accumulation in the brain is associated with peripheral T cell alterations.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 12, p. 5642, doi. 10.1002/alz.13136
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- Article
A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41986-0
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- Article
Age-, sex-, and pathology-related variability in brain structure and cognition.
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- Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02572-6
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- Article
Age-, sex-, and pathology-related variability in brain structure and cognition.
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- Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02572-6
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- Article
Aquaporin 4 is associated with cerebral amyloid‐beta and tau deposits in mouse models.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.059727
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- Article
Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications.
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- 2022
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- journal article
Lifestyle Affects Amyloid Burden and Cognition Differently in Men and Women.
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- Annals of Neurology, 2022, v. 92, n. 3, p. 451, doi. 10.1002/ana.26417
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- Article
Non-invasive imaging of tau-targeted probe uptake by whole brain multi-spectral optoacoustic tomography.
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- European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 49, n. 7, p. 2137, doi. 10.1007/s00259-022-05708-w
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- Article
Recent Developments in Positron Emission Tomography Tracers for Proteinopathies Imaging in Dementia.
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- Frontiers in Aging Neuroscience, 2022, v. 13, p. 1, doi. 10.3389/fnagi.2021.751897
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- Article
High‐resolution non‐invasive whole brain imaging of tauopathy in a tauopathy mouse model.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.049083
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- Publication type:
- Article
Diffusion Tensor Imaging Reveals Whole-Brain Microstructural Changes in the P301L Mouse Model of Tauopathy.
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- Neurodegenerative Diseases, 2021, v. 20, n. 5/6, p. 173, doi. 10.1159/000515754
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- Publication type:
- Article
A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23274-x
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- Publication type:
- Article
Lysine acetyltransferase Tip60 acetylates the APP adaptor Fe65 to increase its transcriptional activity.
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- Biological Chemistry, 2021, v. 402, n. 4, p. 481, doi. 10.1515/hsz-2020-0279
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- Publication type:
- Article
Physical activity is associated with lower cerebral beta-amyloid and cognitive function benefits from lifetime experience–a study in exceptional aging.
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- PLoS ONE, 2021, v. 16, n. 2, p. 1, doi. 10.1371/journal.pone.0247225
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- Article
Oligomeric amyloid‐beta 1–42 inhibits antigen presentation: Developing topics.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047296
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- Publication type:
- Article
Transcranial detection of amyloid‐beta at single plaque resolution in vivo with large‐field multifocal illumination fluorescence microscopy: Neuroimaging / animal imaging.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.036413
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- Publication type:
- Article
Volumetric multispectral optoacoustic tomography of beta‐amyloid deposits in whole mouse brain: Neuroimaging / animal imaging.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.037296
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- Publication type:
- Article
GABA and glutamate associate with evidence of preclinical Alzheimer disease in humans: A 7 Tesla MRSI and <sup>11</sup>C‐PIB PET study: Neuroimaging / Optimal neuroimaging measures for early detection.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044175
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- Publication type:
- Article
SWI and phase imaging reveal intracranial calcifications in the P301L mouse model of human tauopathy.
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- MAGMA: Magnetic Resonance Materials in Physics, Biology & Medicine, 2020, v. 33, n. 6, p. 769, doi. 10.1007/s10334-020-00855-3
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- Article
Distinct changes in all major components of the neurovascular unit across different neuropathological stages of Alzheimer's disease.
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- Brain Pathology, 2020, v. 30, n. 6, p. 1056, doi. 10.1111/bpa.12895
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- Publication type:
- Article
Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system.
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- PLoS ONE, 2020, v. 15, n. 9, p. 1, doi. 10.1371/journal.pone.0239584
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- Publication type:
- Article
Oligomeric Forms of Human Amyloid-Beta(1–42) Inhibit Antigen Presentation.
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- Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.01029
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- Article
Reduced uptake of [11C]‐ABP688, a PET tracer for metabolic glutamate receptor 5 in hippocampus and amygdala in Alzheimer's dementia.
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- Brain & Behavior, 2020, v. 10, n. 6, p. 1, doi. 10.1002/brb3.1632
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- Article
A Practical Guide to the Automated Analysis of Vascular Growth, Maturation and Injury in the Brain.
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- Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00244
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- Publication type:
- Article
Functional Brain Network Connectivity Patterns Associated With Normal Cognition at Old-Age, Local β-amyloid, Tau, and APOE4.
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- Frontiers in Aging Neuroscience, 2020, v. 11, p. 1, doi. 10.3389/fnagi.2020.00046
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- Article
The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer's disease.
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- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0846-8
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- Publication type:
- Article
Deleterious role of endothelial lectin-like oxidized low-density lipoprotein receptor-1 in ischaemia/reperfusion cerebral injury.
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- Journal of Cerebral Blood Flow & Metabolism, 2019, v. 39, n. 11, p. 2233, doi. 10.1177/0271678X18793266
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- Article
A fluorescent protein-readout for transcriptional activity reveals regulation of APP nuclear signaling by phosphorylation sites.
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- Biological Chemistry, 2019, v. 400, n. 9, p. 1191, doi. 10.1515/hsz-2019-0125
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- Publication type:
- Article
The secreted APP ectodomain sAPPα, but not sAPPβ, protects neurons against Aβ oligomer-induced dendritic spine loss and increased tau phosphorylation.
- Published in:
- Molecular Brain, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13041-019-0447-2
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- Publication type:
- Article
A human-derived antibody targets misfolded SOD1 and ameliorates motor symptoms in mouse models of amyotrophic lateral sclerosis.
- Published in:
- Science Translational Medicine, 2018, v. 10, n. 470, p. 1, doi. 10.1126/scitranslmed.aah3924
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- Article
O2‐11‐05: EFFECTS OF AGGREGATED HUMAN Aβ 1‐42 ON IMMUNE SURVEILLANCE: EX VIVO AND IN VITRO STUDIES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P649, doi. 10.1016/j.jalz.2018.06.2704
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- Article
P1‐041: 24‐MONTH ANALYSIS OF APOE ε4 CARRIERS IN PRIME: A RANDOMIZED PHASE 1B STUDY OF THE ANTI–AMYLOID BETA MONOCLONAL ANTIBODY ADUCANUMAB.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P283, doi. 10.1016/j.jalz.2018.06.042
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- Publication type:
- Article
O1‐09‐06: 24‐MONTH ANALYSIS OF CHANGE FROM BASELINE IN CLINICAL DEMENTIA RATING SCALE COGNITIVE AND FUNCTIONAL DOMAINS IN PRIME: A RANDOMIZED PHASE 1B STUDY OF THE ANTI–AMYLOID BETA MONOCLONAL ANTIBODY ADUCANUMAB.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P242, doi. 10.1016/j.jalz.2018.06.2383
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- Publication type:
- Article
Extravascular CD3+ T Cells in Brains of Alzheimer Disease Patients Correlate with Tau but Not with Amyloid Pathology: An Immunohistochemical Study.
- Published in:
- Neurodegenerative Diseases, 2018, v. 18, n. 1, p. 49, doi. 10.1159/000486200
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- Publication type:
- Article
Inaugural Charles River World Congress on Animal Models in Drug Discovery and Development.
- Published in:
- Journal of Translational Medicine, 2017, v. 15, p. 1, doi. 10.1186/s12967-017-1274-9
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- Publication type:
- Article
NEUROIMAGING-DEFINED AMYLOID AND CEREBROVASCULAR PATHOLOGY ARE ASSOCIATED WITH A NEUROMETABOLIC SIGNATURE OF ALZHEIMER’S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P20, doi. 10.1016/j.jalz.2017.06.2290
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- Publication type:
- Article
CHANGE FROM BASELINE IN CLINICAL DEMENTIA RATING SCALE COGNITIVE AND FUNCTIONAL DOMAINS IN PRIME, A RANDOMIZED PHASE 1B STUDY OF THE ANTI–AMYLOID BETA MONOCLONAL ANTIBODY ADUCANUMAB (BIIB037).
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P256, doi. 10.1016/j.jalz.2017.06.120
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- Publication type:
- Article
Hippocampal shape alterations are associated with regional Aβ load in cognitively normal elderly individuals.
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- European Journal of Neuroscience, 2017, v. 45, n. 10, p. 1241, doi. 10.1111/ejn.13408
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- Publication type:
- Article
Memory performance-related dynamic brain connectivity indicates pathological burden and genetic risk for Alzheimer's disease.
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- Alzheimer's Research & Therapy, 2017, v. 9, p. 1, doi. 10.1186/s13195-017-0249-7
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- Publication type:
- Article
Subcortical Shape Changes, Hippocampal Atrophy and Cortical Thinning in Future Alzheimer's Disease Patients.
- Published in:
- Frontiers in Aging Neuroscience, 2017, v. 9, p. 1, doi. 10.3389/fnagi.2017.00038
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- Publication type:
- Article
ROLE OF THE ADAPTIVE IMMUNE SYSTEM IN CEREBRAL BETA-AMYLOIDOSIS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P362, doi. 10.1016/j.jalz.2016.06.671
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- Publication type:
- Article
CLINICAL DEMENTIA RATING-SUM OF BOXES RESPONDER ANALYSIS IN PRIME: A RANDOMIZED PHASE 1B STUDY OF THE ANTI-AMYLOID BETA MONOCLONAL ANTIBODY ADUCANUMAB (BIIB037).
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P416, doi. 10.1016/j.jalz.2016.06.787
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- Publication type:
- Article
Tau pathology-dependent remodelling of cerebral arteries precedes Alzheimer's disease-related microvascular cerebral amyloid angiopathy.
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- Acta Neuropathologica, 2016, v. 131, n. 5, p. 737, doi. 10.1007/s00401-016-1560-2
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- Publication type:
- Article
Reduced β-amyloid pathology in an APP transgenic mouse model of Alzheimer's disease lacking functional B and T cells.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, p. 1, doi. 10.1186/s40478-015-0251-x
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- Publication type:
- Article