Works matching AU Nishitoh, Hideki

Results: 26

RbAp48 is essential for viability of vertebrate cells and plays a role in chromosome stability.

Published in:

Chromosome Research, 2016, v. 24, n. 2, p. 161, doi. 10.1007/s10577-015-9510-8

By:

Satrimafitrah, Pasjan;
Barman, Hirak;
Ahmad, Ahyar;
Nishitoh, Hideki;
Nakayama, Tatsuo;
Fukagawa, Tatsuo;
Takami, Yasunari

Publication type:

Article

ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

Published in:

Nature Immunology, 2005, v. 6, n. 6, p. 587, doi. 10.1038/ni1200

By:

Matsuzawa, Atsushi;
Saegusa, Kaoru;
Noguchi, Takuya;
Sadamitsu, Chiharu;
Nishitoh, Hideki;
Nagai, Shigenori;
Koyasu, Shigeo;
Matsumoto, Kunihiro;
Takeda, Kohsuke;
Ichijo, Hidenori

Publication type:

Article

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

Published in:

EMBO Journal, 1998, v. 17, n. 9, p. 2596, doi. 10.1093/emboj/17.9.2596

By:

Saitoh, Masao;
Nishitoh, Hideki;
Fujii, Makiko;
Takeda, Kohsuke;
Tobiume, Kei;
Sawada, Yasuhiro;
Kawabata, Masahiro;
Miyazono, Kohei;
Ichijo, Hidenori

Publication type:

Article

Protein kinase Cθ gene expression is oppositely regulated by GCN5 and EBF1 in immature B cells.

Published in:

FEBS Letters, 2014, v. 588, n. 9, p. 1739, doi. 10.1016/j.febslet.2014.03.025

By:

Kikuchi, Hidehiko;
Nakayama, Masami;
Kuribayashi, Futoshi;
Imajoh-Ohmi, Shinobu;
Nishitoh, Hideki;
Takami, Yasunari;
Nakayama, Tatsuo

Publication type:

Article

Paired box gene 5 isoforms A and B have different functions in transcriptional regulation of B cell development-related genes in immature B cells.

Published in:

Microbiology & Immunology, 2015, v. 59, n. 7, p. 426, doi. 10.1111/1348-0421.12272

By:

Kikuchi, Hidehiko;
Nakayama, Masami;
Kuribayashi, Futoshi;
Mimuro, Hitomi;
Imajoh‐Ohmi, Shinobu;
Nishitoh, Hideki;
Takami, Yasunari;
Nakayama, Tatsuo

Publication type:

Article

Histone acetyltransferase p300/CBP-associated factor is an effective suppressor of secretory immunoglobulin synthesis in immature B cells.

Published in:

Microbiology & Immunology, 2015, v. 59, n. 4, p. 243, doi. 10.1111/1348-0421.12237

By:

Kikuchi, Hidehiko;
Nakayama, Masami;
Kawai, Chikage;
Kuribayashi, Futoshi;
Mimuro, Hitomi;
Imajoh‐Ohmi, Shinobu;
Nishitoh, Hideki;
Takami, Yasunari;
Nakayama, Tatsuo

Publication type:

Article

Chemical chaperones ameliorate neurodegenerative disorders in Derlin-1-deficient mice via improvement of cholesterol biosynthesis.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-26370-0

By:

Sugiyama, Takashi;
Murao, Naoya;
Kadowaki, Hisae;
Nishitoh, Hideki

Publication type:

Article

Signaling Pathways from the Endoplasmic Reticulum and Their Roles in Disease.

Published in:

Genes, 2013, v. 4, n. 3, p. 306, doi. 10.3390/genes4030306

By:

Hisae Kadowaki;
Hideki Nishitoh

Publication type:

Article

Involvement of ASK1 in Ca²+-induced p38 MAP kinase activation.

Published in:

EMBO Reports, 2004, v. 5, n. 2, p. 161, doi. 10.1038/sj.embor.7400072

By:

Takeda, Kohsuke;
Matsuzawa, Atsushi;
Nishitoh, Hideki;
Tobiume, Kei;
Kishida, Satoshi;
Ninomiya-Tsuji, Jun;
Matsumoto, Kunihiro;
Ichijo, Hidenori

Publication type:

Article

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis.

Published in:

2001

By:

Tobiume, Kei;
Matsuzawa, Atsushi;
Takahashi, Takumi;
Nishitoh, Hideki;
Morita, Kei-ichi;
Takeda, Kohsuke;
Minowa, Osamu;
Miyazono, Kohei;
Noda, Tetsuo;
Ichijo, Hidenori

Publication type:

Report

Apoptosis Signal-Regulating Kinase 1-Mediated Signaling Pathway Regulates Nitric Oxide-Induced Activator Protein-1 Activation in Human Bronchial Epithelial Cells.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2003, v. 167, n. 6, p. 856, doi. 10.1164/rccm.2204042

By:

Itsuro Jibiki;
Shu Hashimoto;
Shuichiro Maruoka;
Yasuhiro Gon;
Atsushi Matsuzawa;
Hideki Nishitoh;
Hidenori Ichijo;
Takashi Horie

Publication type:

Article

Etomoxir suppresses the expression of PPARγ2 and inhibits the thermogenic gene induction of brown adipocytes through pathways other than β-oxidation inhibition.

Published in:

Journal of Biochemistry, 2025, v. 177, n. 3, p. 203, doi. 10.1093/jb/mvae092

By:

Shimura, Hiroki;
Yamamoto, Sota;
Shiiba, Isshin;
Oikawa, Mami;
Uchinomiya, Shohei;
Ojida, Akio;
Yanagi, Shigeru;
Kadowaki, Hisae;
Nishitoh, Hideki;
Fukuda, Toshifumi;
Nagashima, Shun;
Yamaguchi, Tomoyuki

Publication type:

Article

Neurodegenerative diseases associated with the disruption of proteostasis and their therapeutic strategies using chemical chaperones.

Published in:

Journal of Biochemistry, 2024, v. 176, n. 3, p. 179, doi. 10.1093/jb/mvae048

By:

Sugiyama, Takashi;
Nishitoh, Hideki

Publication type:

Article

Paradigm shift from 'Compartment' to 'Zone' in the understanding of organelles.

Published in:

Journal of Biochemistry, 2019, v. 165, n. 2, p. 97, doi. 10.1093/jb/mvy107

By:

Nishitoh, Hideki

Publication type:

Article

Role of the unfolded protein response in the development of central nervous system.

Published in:

Journal of Biochemistry, 2017, v. 162, n. 3, p. 155, doi. 10.1093/jb/mvx047

By:

Naoya Murao;
Hideki Nishitoh

Publication type:

Article

CHOP is a multifunctional transcription factor in the ER stress response.

Published in:

Journal of Biochemistry, 2012, v. 151, n. 3, p. 217, doi. 10.1093/jb/mvr143

By:

Nishitoh, Hideki

Publication type:

Article

ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney.

Published in:

Nature Communications, 2012, v. 3, n. 12, p. 1285, doi. 10.1038/ncomms2283

By:

Naguro, Isao;
Umeda, Tsuyoshi;
Kobayashi, Yumie;
Maruyama, Junichi;
Hattori, Kazuki;
Shimizu, Yutaka;
Kataoka, Keiichiro;
Kim-Mitsuyama, Shokei;
Uchida, Shinichi;
Vandewalle, Alain;
Noguchi, Takuya;
Nishitoh, Hideki;
Matsuzawa, Atsushi;
Takeda, Kohsuke;
Ichijo, Hidenori

Publication type:

Article

A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants.

Published in:

Annals of Neurology, 2012, v. 72, n. 5, p. 739, doi. 10.1002/ana.23668

By:

Fujisawa, Takao;
Homma, Kengo;
Yamaguchi, Namiko;
Kadowaki, Hisae;
Tsuburaya, Naomi;
Naguro, Isao;
Matsuzawa, Atsushi;
Takeda, Kohsuke;
Takahashi, Yuji;
Goto, Jun;
Tsuji, Shoji;
Nishitoh, Hideki;
Ichijo, Hidenori

Publication type:

Article

CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.

Published in:

EMBO Journal, 2010, v. 29, n. 15, p. 2501, doi. 10.1038/emboj.2010.141

By:

Maruyama, Takeshi;
Kadowaki, Hisae;
Okamoto, Noriaki;
Nagai, Atsushi;
Naguro, Isao;
Matsuzawa, Atsushi;
Shibuya, Hiroshi;
Tanaka, Keiji;
Murata, Shigeo;
Takeda, Kohsuke;
Nishitoh, Hideki;
Ichijo, Hidenori

Publication type:

Article

ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.

Published in:

EMBO Journal, 2009, v. 28, n. 7, p. 843, doi. 10.1038/emboj.2009.32

By:

Iriyama, Takayuki;
Takeda, Kohsuke;
Nakamura, Hiromi;
Morimoto, Yoshifumi;
Kuroiwa, Takumi;
Mizukami, Junya;
Umeda, Tsuyoshi;
Noguchi, Takuya;
Naguro, Isao;
Nishitoh, Hideki;
Saegusa, Kaoru;
Tobiume, Kei;
Homma, Toshiki;
Shimada, Yutaka;
Tsuda, Hitoshi;
Aiko, Satoshi;
Imoto, Issei;
Inazawa, Johji;
Chida, Kazuhiro;
Kamei, Yoshimasa

Publication type:

Article

Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress.

Published in:

EMBO Journal, 2001, v. 20, n. 21, p. 6028, doi. 10.1093/emboj/20.21.6028

By:

Kei-Ichi Morita;
Saitoh, Masao;
Kei Tobiume;
Matsuura, Hiroshi;
Enomoto, Shoji;
Nishitoh, Hideki;
Ichiio, Hidenori

Publication type:

Article

Stress responses from the endoplasmic reticulum in cancer.

Published in:

Frontiers in Oncology, 2015, v. 5, p. 1, doi. 10.3389/fonc.2015.00093

By:

Hironori Kato;
Hideki Nishitoh

Publication type:

Article

The Derlin-1-Stat5b axis maintains homeostasis of adult hippocampal neurogenesis.

Published in:

EMBO Reports, 2024, v. 25, n. 8, p. 3678, doi. 10.1038/s44319-024-00205-7

By:

Murao, Naoya;
Matsuda, Taito;
Kadowaki, Hisae;
Matsushita, Yosuke;
Tanimoto, Kousuke;
Katagiri, Toyomasa;
Nakashima, Kinichi;
Nishitoh, Hideki

Publication type:

Article

The ASK1-specific inhibitors K811 and K812 prolong survival in a mouse model of amyotrophic lateral sclerosis.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 2, p. 245, doi. 10.1093/hmg/ddv467

By:

Takao Fujisawa;
Motoo Takahashi;
Yuka Tsukamoto;
Namiko Yamaguchi;
Masayoshi Nakoji;
Megumi Endo;
Hiroshi Kodaira;
Yuki Hayashi;
Hideki Nishitoh;
Isao Naguro;
Kengo Homma;
Hidenori Ichijo

Publication type:

Article

A mouse model reveals that Mfsd2a is critical for unfolded protein response upon exposure to tunicamycin.

Published in:

Human Cell, 2017, v. 30, n. 2, p. 88, doi. 10.1007/s13577-016-0153-7

By:

Moritake, Hiroshi;
Obara, Megumi;
Saito, Yusuke;
Kashimada, Ayako;
Takagi, Masatoshi;
Funakoshi-Tago, Megumi;
Fukuyama, Tomofusa;
Yoshioka, Mikio;
Inoue, Akira;
Komatsu, Hiroyuki;
Nishitoh, Hideki;
Kataoka, Hiroaki;
Nunoi, Hiroyuki

Publication type:

Article

Endoplasmic reticulum quality control by garbage disposal.

Published in:

FEBS Journal, 2019, v. 286, n. 2, p. 232, doi. 10.1111/febs.14589

By:

Kadowaki, Hisae;
Nishitoh, Hideki

Publication type:

Article