Works by Ninomiya, Kiyofumi

Results: 32

Evaluation of Salacia Species as Anti-diabetic Natural Resources Based on Quantitative Analysis of Eight Sulphonium Constituents: A New Class of α-Glucosidase Inhibitors.

Published in:

Phytochemical Analysis, 2014, v. 25, n. 6, p. 544, doi. 10.1002/pca.2525

By:

Akaki, Junji;
Morikawa, Toshio;
Miyake, Sohachiro;
Ninomiya, Kiyofumi;
Okada, Mayumi;
Tanabe, Genzoh;
Pongpiriyadacha, Yutana;
Yoshikawa, Masayuki;
Muraoka, Osamu

Publication type:

Article

Collagen Synthesis-Promoting Effects of Andiroba Oil and its Limonoid Constituents in Normal Human Dermal Fibroblasts.

Published in:

Journal of Oleo Science, 2018, v. 67, n. 10, p. 1271, doi. 10.5650/jos.ess18143

By:

Toshio Morikawa;
Akifumi Nagatomo;
Kayako Kitazawa;
Osamu Muraoka;
Takashi Kikuchi;
Takeshi Yamada;
Reiko Tanaka;
Kiyofumi Ninomiya

Publication type:

Article

A Gedunin-Type Limonoid, 7-Deacetoxy-7-Oxogedunin, from Andiroba (Carapa guianensis Aublet) Reduced Intracellular Triglyceride Content and Enhanced Autophagy in HepG2 Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13141, doi. 10.3390/ijms232113141

By:

Nagatomo, Akifumi;
Ninomiya, Kiyofumi;
Marumoto, Shinsuke;
Sakai, Chie;
Watanabe, Shuta;
Ishikawa, Wakana;
Manse, Yoshiaki;
Kikuchi, Takashi;
Yamada, Takeshi;
Tanaka, Reiko;
Muraoka, Osamu;
Morikawa, Toshio

Publication type:

Article

Glucose Tolerance-Improving Activity of Helichrysoside in Mice and Its Structural Requirements for Promoting Glucose and Lipid Metabolism.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 24, p. 6322, doi. 10.3390/ijms20246322

By:

Morikawa, Toshio;
Nagatomo, Akifumi;
Oka, Takahiro;
Miki, Yoshinobu;
Taira, Norihisa;
Shibano-Kitahara, Megumi;
Hori, Yuichiro;
Muraoka, Osamu;
Ninomiya, Kiyofumi

Publication type:

Article

Ergostane-Type Sterols from King Trumpet Mushroom (Pleurotus eryngii) and Their Inhibitory Effects on Aromatase.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 11, p. 2479, doi. 10.3390/ijms18112479

By:

Takashi Kikuchi;
Naoki Motoyashiki;
Takeshi Yamada;
Kanae Shibatani;
Kiyofumi Ninomiya;
Toshio Morikawa;
Reiko Tanaka

Publication type:

Article

Quantitative Determination of Stilbenoids and Dihydroisocoumarins in Shorea roxburghii and Evaluation of Their Hepatoprotective Activity.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 2, p. 451, doi. 10.3390/ijms18020451

By:

Kiyofumi Ninomiya;
Saowanee Chaipech;
Yusuke Kunikata;
Ryohei Yagi;
Yutana Pongpiriyadacha;
Osamu Muraoka;
Toshio Morikawa

Publication type:

Article

The Antiproliferative Effect of Chakasaponins I and II, Floratheasaponin A, and Epigallocatechin 3-O-Gallate Isolated from Camellia sinensis on Human Digestive Tract Carcinoma Cell Lines.

Published in:

International Journal of Molecular Sciences, 2016, v. 17, n. 12, p. 1979, doi. 10.3390/ijms17121979

By:

Niichiro Kitagawa;
Toshio Morikawa;
Chiaki Motai;
Kiyofumi Ninomiya;
Shuhei Okugawa;
Ayaka Nishida;
Masayuki Yoshikawa;
Osamu Muraoka

Publication type:

Article

Hepatoprotective Limonoids from Andiroba (Carapa guianensis).

Published in:

International Journal of Molecular Sciences, 2016, v. 17, n. 4, p. 591, doi. 10.3390/ijms17040591

By:

Kiyofumi Ninomiya;
Seiya Miyazawa;
Kaiten Ozeki;
Natsuko Matsuo;
Osamu Muraoka;
Takashi Kikuchi;
Takeshi Yamada;
Reiko Tanaka;
Toshio Morikawa

Publication type:

Article

Salacinol and Related Analogs: New Leads for Type 2 Diabetes Therapeutic Candidates from the Thai Traditional Natural Medicine Salacia chinensis.

Published in:

2015

By:

Toshio Morikawa;
Junji Akaki;
Kiyofumi Ninomiya;
Eri Kinouchi;
Genzoh Tanabe;
Yutana Pongpiriyadacha;
Masayuki Yoshikawa;
Osamu Muraoka

Publication type:

Journal Article

Experimental Study. INHIBITORY MECHANISM OF COSTUNOLIDE, A SESQUITERPENE LACTONE ISOLATED FROM LAURUS NOBILIS, ON BLOOD-ETHANOL ELEVATION IN RATS: INVOLVEMENT OF INHIBITION OF GASTRIC EMPTYING AND INCREASE IN GASTRIC JUICE SECRETION.

Published in:

Alcohol & Alcoholism, 2002, v. 37, n. 2, p. 121, doi. 10.1093/alcalc/37.2.121

By:

Matsuda, Hisashi;
Shimoda, Hiroshi;
Ninomiya, Kiyofumi;
Yoshikawa, Masayuki

Publication type:

Article

Correction: Ameliorative effect of bofutsushosan (Fangfengtongshengsan) extract on the progression of aging-induced obesity.

Published in:

2025

By:

Saeki, Takafumi;
Yamamoto, Saya;
Akaki, Junji;
Tanaka, Takahiro;
Nakasone, Misaki;
Ikeda, Hidemasa;
Wang, Wei;
Inoue, Makoto;
Manse, Yoshiaki;
Ninomiya, Kiyofumi;
Morikawa, Toshio

Publication type:

Correction Notice

Ameliorative effect of bofutsushosan (Fangfengtongshengsan) extract on the progression of aging-induced obesity.

Published in:

Journal of Natural Medicines, 2024, v. 78, n. 3, p. 576, doi. 10.1007/s11418-024-01803-4

By:

Saeki, Takafumi;
Yamamoto, Saya;
Akaki, Junji;
Tanaka, Takahiro;
Nakasone, Misaki;
Ikeda, Hidemasa;
Wang, Wei;
Inoue, Makoto;
Manse, Yoshiaki;
Ninomiya, Kiyofumi;
Morikawa, Toshio

Publication type:

Article

Alkylphthalides with intracellular triglyceride metabolism-promoting activity from the rhizomes of Cnidium officinale Makino.

Published in:

Journal of Natural Medicines, 2024, v. 78, n. 3, p. 709, doi. 10.1007/s11418-024-01799-x

By:

Morikawa, Toshio;
Inoue, Naoki;
Yamamoto, Saya;
Shiotani, Miyuki;
Manse, Yoshiaki;
Ninomiya, Kiyofumi

Publication type:

Article

Ursane-type triterpene oligoglycosides with anti-hepatosteatosis and anti-hyperlipidemic activity from the leaves of Ilex paraguariensis A. St.-Hil.

Published in:

Journal of Natural Medicines, 2022, v. 76, n. 3, p. 654, doi. 10.1007/s11418-022-01614-5

By:

Nagatomo, Akifumi;
Inoue, Naoki;
Konno, Takuya;
Xu, Yin;
Sakamoto, Chinatsu;
Sone, Mayuko;
Shibasaka, Aya;
Muraoka, Osamu;
Ninomiya, Kiyofumi;
Yoshikawa, Masayuki;
Manse, Yoshiaki;
Morikawa, Toshio

Publication type:

Article

A review of antidiabetic active thiosugar sulfoniums, salacinol and neokotalanol, from plants of the genus Salacia.

Published in:

Journal of Natural Medicines, 2021, v. 75, n. 3, p. 449, doi. 10.1007/s11418-021-01522-0

By:

Morikawa, Toshio;
Ninomiya, Kiyofumi;
Tanabe, Genzoh;
Matsuda, Hisashi;
Yoshikawa, Masayuki;
Muraoka, Osamu

Publication type:

Article

Salacia chinensis stem extract and its thiosugar sulfonium constituent, neokotalanol, improves HbA1c levels in ob/ob mice.

Published in:

Journal of Natural Medicines, 2019, v. 73, n. 3, p. 584, doi. 10.1007/s11418-019-01311-w

By:

Kobayashi, Masakazu;
Akaki, Junji;
Yamaguchi, Yasuyo;
Yamasaki, Hiroo;
Ninomiya, Kiyofumi;
Pongpiriyadacha, Yutana;
Yoshikawa, Masayuki;
Muraoka, Osamu;
Morikawa, Toshio

Publication type:

Article

Degranulation inhibitors from the arils of Myristica fragrans in antigen-stimulated rat basophilic leukemia cells.

Published in:

Journal of Natural Medicines, 2018, v. 72, n. 2, p. 464, doi. 10.1007/s11418-017-1170-x

By:

Morikawa, Toshio;
Hachiman, Ikuko;
Ninomiya, Kiyofumi;
Hata, Hiroki;
Sugawara, Kaoru;
Muraoka, Osamu;
Matsuda, Hisashi

Publication type:

Article

Two new aromatic glycosides, elengiosides A and B, from the flowers of Mimusops elengi.

Published in:

Journal of Natural Medicines, 2018, v. 72, n. 2, p. 542, doi. 10.1007/s11418-017-1160-z

By:

Morikawa, Toshio;
Manse, Yoshiaki;
Koda, Mika;
Chaipech, Saowanee;
Pongpiriyadacha, Yutana;
Muraoka, Osamu;
Ninomiya, Kiyofumi

Publication type:

Article

Ellagic acid glycosides with hepatoprotective activity from traditional Tibetan medicine Potentilla anserina.

Published in:

Journal of Natural Medicines, 2018, v. 72, n. 1, p. 317, doi. 10.1007/s11418-017-1137-y

By:

Morikawa, Toshio;
Imura, Katsuya;
Akagi, Yoshinori;
Muraoka, Osamu;
Ninomiya, Kiyofumi

Publication type:

Article

Acylated oleanane-type triterpene saponins from the flowers of Bellis perennis show anti-proliferative activities against human digestive tract carcinoma cell lines.

Published in:

Journal of Natural Medicines, 2016, v. 70, n. 3, p. 435, doi. 10.1007/s11418-016-0998-9

By:

Ninomiya, Kiyofumi;
Motai, Chiaki;
Nishida, Eriko;
Kitagawa, Niichiro;
Yoshihara, Kazuya;
Hayakawa, Takao;
Muraoka, Osamu;
Li, Xuezheng;
Nakamura, Seikou;
Yoshikawa, Masayuki;
Matsuda, Hisashi;
Morikawa, Toshio

Publication type:

Article

Simultaneous quantitative analysis of 12 methoxyflavones with melanogenesis inhibitory activity from the rhizomes of Kaempferia parviflora.

Published in:

Journal of Natural Medicines, 2016, v. 70, n. 2, p. 179, doi. 10.1007/s11418-015-0955-z

By:

Ninomiya, Kiyofumi;
Matsumoto, Taku;
Chaipech, Saowanee;
Miyake, Sohachiro;
Katsuyama, Yushi;
Tsuboyama, Akihiro;
Pongpiriyadacha, Yutana;
Hayakawa, Takao;
Muraoka, Osamu;
Morikawa, Toshio

Publication type:

Article

Phenylethanoid and phenylpropanoid glycosides with melanogenesis inhibitory activity from the flowers of Narcissus tazetta var. chinensis.

Published in:

Journal of Natural Medicines, 2016, v. 70, n. 1, p. 89, doi. 10.1007/s11418-015-0941-5

By:

Morikawa, Toshio;
Ninomiya, Kiyofumi;
Kuramoto, Hiroyuki;
Kamei, Iyori;
Yoshikawa, Masayuki;
Muraoka, Osamu

Publication type:

Article

Dipeptidyl peptidase-IV inhibitory activity of dimeric dihydrochalcone glycosides from flowers of Helichrysum arenarium.

Published in:

Journal of Natural Medicines, 2015, v. 69, n. 4, p. 494, doi. 10.1007/s11418-015-0914-8

By:

Morikawa, Toshio;
Ninomiya, Kiyofumi;
Akaki, Junji;
Kakihara, Namiko;
Kuramoto, Hiroyuki;
Matsumoto, Yurie;
Hayakawa, Takao;
Muraoka, Osamu;
Wang, Li-Bo;
Wu, Li-Jun;
Nakamura, Seikou;
Yoshikawa, Masayuki;
Matsuda, Hisashi

Publication type:

Article

Acylated phenylethanoid glycosides, echinacoside and acteoside from Cistanche tubulosa, improve glucose tolerance in mice.

Published in:

Journal of Natural Medicines, 2014, v. 68, n. 3, p. 561, doi. 10.1007/s11418-014-0837-9

By:

Morikawa, Toshio;
Ninomiya, Kiyofumi;
Imamura, Mio;
Akaki, Junji;
Fujikura, Shota;
Pan, Yingni;
Yuan, Dan;
Yoshikawa, Masayuki;
Jia, Xiaoguang;
Li, Zheng;
Muraoka, Osamu

Publication type:

Article

Dimeric pyrrolidinoindoline-type alkaloids with melanogenesis inhibitory activity in flower buds of Chimonanthus praecox.

Published in:

Journal of Natural Medicines, 2014, v. 68, n. 3, p. 539, doi. 10.1007/s11418-014-0832-1

By:

Morikawa, Toshio;
Nakanishi, Yusuke;
Ninomiya, Kiyofumi;
Matsuda, Hisashi;
Nakashima, Souichi;
Miki, Hisako;
Miyashita, Yu;
Yoshikawa, Masayuki;
Hayakawa, Takao;
Muraoka, Osamu

Publication type:

Article

Quantitative analysis of acylated oleanane-type triterpene saponins, chakasaponins I-III and floratheasaponins A-F, in the flower buds of Camellia sinensis from different regional origins.

Published in:

Journal of Natural Medicines, 2012, v. 66, n. 4, p. 608, doi. 10.1007/s11418-012-0627-1

By:

Morikawa, Toshio;
Miyake, Sohachiro;
Miki, Yoshinobu;
Ninomiya, Kiyofumi;
Yoshikawa, Masayuki;
Muraoka, Osamu

Publication type:

Article

Anti-hyperlipidemic constituents from the bark of Shorea roxburghii.

Published in:

Journal of Natural Medicines, 2012, v. 66, n. 3, p. 516, doi. 10.1007/s11418-011-0619-6

By:

Morikawa, Toshio;
Chaipech, Saowanee;
Matsuda, Hisashi;
Hamao, Makoto;
Umeda, Yohei;
Sato, Hiroki;
Tamura, Haruka;
Ninomiya, Kiyofumi;
Yoshikawa, Masayuki;
Pongpiriyadacha, Yutana;
Hayakawa, Takao;
Muraoka, Osamu

Publication type:

Article

New flav-3-en-3-ol glycosides, kaempferiaosides C and D, and acetophenone glycosides, kaempferiaosides E and F, from the rhizomes of Kaempferia parviflora.

Published in:

Journal of Natural Medicines, 2012, v. 66, n. 3, p. 486, doi. 10.1007/s11418-011-0611-1

By:

Chaipech, Saowanee;
Morikawa, Toshio;
Ninomiya, Kiyofumi;
Yoshikawa, Masayuki;
Pongpiriyadacha, Yutana;
Hayakawa, Takao;
Muraoka, Osamu

Publication type:

Article

Promoting the effect of chemical constituents from the flowers of Poacynum hendersonii on adipogenesis in 3T3-L1 cells.

Published in:

Journal of Natural Medicines, 2012, v. 66, n. 1, p. 39, doi. 10.1007/s11418-011-0549-3

By:

Morikawa, Toshio;
Imura, Katsuya;
Miyake, Sohachiro;
Ninomiya, Kiyofumi;
Matsuda, Hisashi;
Yamashita, Chihiro;
Muraoka, Osamu;
Hayakawa, Takao;
Yoshikawa, Masayuki

Publication type:

Article

Quantitative analysis of neosalacinol and neokotalanol, another two potent α-glucosidase inhibitors from Salacia species, by LC-MS with ion pair chromatography.

Published in:

Journal of Natural Medicines, 2011, v. 65, n. 1, p. 142, doi. 10.1007/s11418-010-0474-x

By:

Muraoka, Osamu;
Morikawa, Toshio;
Miyake, Sohachiro;
Akaki, Junji;
Ninomiya, Kiyofumi;
Pongpiriyadacha, Yutana;
Yoshikawa, Masayuki

Publication type:

Article

Labdane-Type Diterpenes, Galangalditerpenes A-C, with Melanogenesis Inhibitory Activity from the Fruit of Alpinia galanga.

Published in:

Molecules, 2017, v. 22, n. 12, p. 2279, doi. 10.3390/molecules22122279

By:

Yoshiaki Manse;
Kiyofumi Ninomiya;
Ryosuke Nishi;
Yoshinori Hashimoto;
Chaipech, Saowanee;
Osamu Muraoka;
Toshio Morikawa

Publication type:

Article

Quantitative Determination of Alkaloids in Lotus Flower (Flower Buds of Nelumbo nucifera) and Their Melanogenesis Inhibitory Activity.

Published in:

Molecules, 2016, v. 21, n. 7, p. 930, doi. 10.3390/molecules21070930

By:

Toshio Morikawa;
Niichiro Kitagawa;
Genzoh Tanabe;
Kiyofumi Ninomiya;
Shuhei Okugawa;
Chiaki Motai;
Iyori Kamei;
Masayuki Yoshikawa;
Lee, I-Jung;
Osamu Muraoka

Publication type:

Article