Works matching AU Nils‐Göran Larsson

Results: 84

Purifying selection of mtDNA and its implications for understanding evolution and mitochondrial disease.

Published in:

2008

By:

Stewart, James Bruce;
Freyer, Christoph;
Elson, Joanna L.;
Larsson, Nils-Göran;
Larsson, Nils-Göran

Publication type:

research

TFAM forces mtDNA to make a U-turn.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 11, p. 1179, doi. 10.1038/nsmb.2167

By:

Hallberg, B Martin;
Larsson, Nils-Göran

Publication type:

Article

Stable transfection of a human lymphoma line by sub-genomic fragments of Epstein-Barr virus DNA to measure humoral and cellular immunity to the corresponding proteins.

Published in:

International Journal of Cancer, 1987, v. 40, n. 3, p. 389, doi. 10.1002/ijc.2910400318

By:

Welinder, Christina;
Larsson, Nils-Göran;
Szigeti, Robert;
Ehlin-Henriksson, Barbro;
Henle, Gertrude;
Henle, Werner;
Klein, George;
Ricksten, Anne;
Rymo, Lars;
Sulitzeanu, Dov

Publication type:

Article

Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission.

Published in:

Nature Genetics, 2012, v. 44, n. 11, p. 1282, doi. 10.1038/ng.2427

By:

Freyer, Christoph;
Cree, Lynsey M;
Mourier, Arnaud;
Stewart, James B;
Koolmeister, Camilla;
Milenkovic, Dusanka;
Wai, Timothy;
Floros, Vasileios I;
Hagström, Erik;
Chatzidaki, Emmanouella E;
Wiesner, Rudolf J;
Samuels, David C;
Larsson, Nils-Göran;
Chinnery, Patrick F

Publication type:

Article

Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA.

Published in:

Nature Genetics, 2002, v. 31, n. 3, p. 289, doi. 10.1038/ng909

By:

Falkenberg, Maria;
Gaspari, Martina;
Rantanen, Anja;
Trifunovic, Aleksandra;
Larsson, Nils-Göran;
Gustafsson, Claes M.

Publication type:

Article

Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes.

Published in:

Nature Genetics, 2000, v. 26, n. 3, p. 336, doi. 10.1038/81649

By:

Silva, José P.;
Köhler, Martin;
Graff, Caroline;
Oldfors, Anders;
Magnuson, Mark A.;
Berggren, Per-Olof;
Larsson, Nils-Göran

Publication type:

Article

Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression.

Published in:

Nature Genetics, 1999, v. 21, n. 1, p. 133, doi. 10.1038/5089

By:

Wang, Jianming;
Wilhelmsson, Hans;
Graff, Caroline;
Li, Hong;
Oldfors, Anders;
Rustin, Pierre;
Brüning, Jens C.;
Kahn, C. Ronald;
Clayton, David A.;
Barsh, Gregory S.;
Thorén, Peter;
Larsson, Nils-Göran

Publication type:

Article

Tissue distribution and disease manifestations of the tRNA A»G mitochondrial DNA mutation in a case of myoclonus epilepsy and ragged red fibres.

Published in:

Acta Neuropathologica, 1995, v. 90, n. 3, p. 328, doi. 10.1007/BF00296519

By:

Oldfors, Anders;
Holme, Elisabeth;
Tulinius, Már;
Larsson, Nils-Göran

Publication type:

Article

PARKIN is not required to sustain OXPHOS function in adult mammalian tissues.

Published in:

NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00707-0

By:

Filograna, Roberta;
Gerlach, Jule;
Choi, Hae-Na;
Rigoni, Giovanni;
Barbaro, Michela;
Oscarson, Mikael;
Lee, Seungmin;
Tiklova, Katarina;
Ringnér, Markus;
Koolmeister, Camilla;
Wibom, Rolf;
Riggare, Sara;
Nennesmo, Inger;
Perlmann, Thomas;
Wredenberg, Anna;
Wedell, Anna;
Motori, Elisa;
Svenningsson, Per;
Larsson, Nils-Göran

Publication type:

Article

Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels.

Published in:

Journal of Cell Biology, 2015, v. 208, n. 4, p. 429, doi. 10.1083/jcb.201411100

By:

Mourier, Arnaud;
Motori, Elisa;
Brandt, Tobias;
Lagouge, Marie;
Atanassov, Ilian;
Galinier, Anne;
Rappl, Gunter;
Brodesser, Susanne;
Hultenby, Kjell;
Dieterich, Christoph;
Larsson, Nils-Göran

Publication type:

Article

Mitochondrial DNA mutations in disease and aging.

Published in:

Journal of Cell Biology, 2011, v. 193, n. 5, p. 809, doi. 10.1083/jcb.201010024

By:

Chan Bae Park;
Larsson, Nils-Göran

Publication type:

Article

USE OF PRIMARY CULTURES AND CONTINUOUS CELL LINES TO STUDY EFFECTS ON ASTROCYTIC REGULATORY FUNCTIONS.

Published in:

Clinical & Experimental Pharmacology & Physiology, 1995, v. 22, n. 4, p. 284, doi. 10.1111/j.1440-1681.1995.tb01996.x

By:

Walum, Erik;
Eriksson, Gun;
Peterson, Anders;
Holme, Elisabeth;
Larsson, Nils-Göran;
Eriksson, Charlotta;
El-Shamy, Wael

Publication type:

Article

Pathogenetic aspects of the A8344G mutation of mitochondrial DNA associated with MERRF syndrome and multiple symmetric lipomas.

Published in:

Muscle & Nerve, 1995, v. 18, n. S14, p. S102, doi. 10.1002/mus.880181421

By:

Larsson, Nils-Göran;
Tulinius, Mar H.;
Holme, Elisabeth;
Oldfors, Anders

Publication type:

Article

Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications.

Published in:

FASEB Journal, 2014, v. 28, n. 10, p. 4408, doi. 10.1096/fj.14-253971

By:

Vernochet, Cecile;
Damilano, Federico;
Mourier, Arnaud;
Bezy, Olivier;
Mori, Marcelo A.;
Smyth, Graham;
Rosenzweig, Anthony;
Larsson, Nils-Göran;
Kahn, C. Ronald

Publication type:

Article

Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease.

Published in:

FASEB Journal, 2011, v. 25, n. 4, p. 1333, doi. 10.1096/fj.10-173625

By:

Good, Cameron H.;
Hoffman, Alexander F.;
Hoffer, Barry J.;
Chefer, Vladimir I.;
Shippenberg, Toni S.;
Bäckman, Cristina M.;
Larsson, Nils-Göran;
Olson, Lars;
Gellhaar, Sandra;
Galter, Dagmar;
Lupica, Carl R.

Publication type:

Article

Accurate mapping of mitochondrial DNA deletions and duplications using deep sequencing.

Published in:

PLoS Genetics, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pgen.1009242

By:

Basu, Swaraj;
Xie, Xie;
Uhler, Jay P.;
Hedberg-Oldfors, Carola;
Milenkovic, Dusanka;
Baris, Olivier R.;
Kimoloi, Sammy;
Matic, Stanka;
Stewart, James B.;
Larsson, Nils-Göran;
Wiesner, Rudolf J.;
Oldfors, Anders;
Gustafsson, Claes M.;
Falkenberg, Maria;
Larsson, Erik

Publication type:

Article

Overexpression of the mitochondrial methyltransferase TFB1M in the mouse does not impact mitoribosomal ethylation status or hearing.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 25, p. 7286, doi. 10.1093/hmg/ddv427

By:

Lee, Seungmin;
Rose, Simon;
Metodiev, Metodi D.;
Becker, Lore;
Vernaleken, Alexandra;
Klopstock, Thomas;
Durner, Valerie Gailus;
Fuchs, Helmut;
De Angelis, Martin Hrabê;
Douthwaite, Stephen;
Larsson, Nils-Göran

Publication type:

Article

A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 23, p. 6345, doi. 10.1093/hmg/ddu352

By:

Wilson, William C.;
Hornig-Do, Hue-Tran;
Bruni, Francesco;
Chang, Jeong Ho;
Jourdain, Alexis A.;
Martinou, Jean-Claude;
Falkenberg, Maria;
Spåhr, Henrik;
Larsson, Nils-Göran;
Lewis, Richard J.;
Hewitt, Lorraine;
Baslé, Arnaud;
Cross, Harold E.;
Tong, Liang;
Lebel, Robert R.;
Crosby, Andrew H.;
Chrzanowska-Lightowlers, Zofia M. A.;
Lightowlers, Robert N.

Publication type:

Article

Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 21, p. 5733, doi. 10.1093/hmg/ddu288

By:

Sharoyko, Vladimir V.;
Abels, Mia;
Sun, Jiangming;
Nicholas, Lisa M.;
Mollet, Ines Guerra;
Stamenkovic, Jelena A.;
Göhring, Isabel;
Malmgren, Siri;
Storm, Petter;
Fadista, João;
Spégel, Peter;
Metodiev, Metodi D.;
Larsson, Nils-Göran;
Eliasson, Lena;
Wierup, Nils;
Mulder, Hindrik

Publication type:

Article

Loss of LRPPRC causes ATP synthase deficiency.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 10, p. 2580, doi. 10.1093/hmg/ddt652

By:

Mourier, Arnaud;
Ruzzenente, Benedetta;
Brandt, Tobias;
Kühlbrandt, Werner;
Larsson, Nils-Göran

Publication type:

Article

TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication.

Published in:

Human Molecular Genetics, 2013, v. 22, n. 10, p. 1983, doi. 10.1093/hmg/ddt051

By:

Milenkovic, Dusanka;
Matic, Stanka;
Kühl, Inge;
Ruzzenente, Benedetta;
Freyer, Christoph;
Jemt, Elisabeth;
Chan Bae Park;
Falkenberg, Maria;
Larsson, Nils-Göran

Publication type:

Article

The role of mitochondria in aging.

Published in:

2013

By:

Bratic, Ana;
Larsson, Nils-Göran

Publication type:

journal article

The role of mitochondria in aging.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 3, p. 951, doi. 10.1172/JCI64125

By:

Bratic, Ana;
Larsson, Nils-Göran

Publication type:

Article

AFG3L2 supports mitochondrial protein synthesis and Purkinje cell survival.

Published in:

2012

By:

Almajan ER;
Richter R;
Paeger L;
Martinelli P;
Barth E;
Decker T;
Larsson NG;
Kloppenburg P;
Langer T;
Rugarli EI;
Almajan, Eva R;
Richter, Ricarda;
Paeger, Lars;
Martinelli, Paola;
Barth, Esther;
Decker, Thorsten;
Larsson, Nils-Göran;
Kloppenburg, Peter;
Langer, Thomas;
Rugarli, Elena I

Publication type:

journal article

Regulation of mitochondrial DNA copy number during spermatogenesis.

Published in:

Human Reproduction, 2000, v. 15, n. suppl_2, p. 86, doi. 10.1093/humrep/15.suppl_2.86

By:

Rantanen, Anja;
Larsson, Nils-Göran

Publication type:

Article

Mitochondrial phosphoproteomes are functionally specialized across tissues.

Published in:

Life Science Alliance, 2024, v. 7, n. 2, p. 1, doi. 10.26508/lsa.202302147

By:

Hansen, Fynn M.;
Kremer, Laura S.;
Karayel, Ozge;
Bludau, Isabell;
Larsson, Nils-Göran;
Kühl, Inge;
Mann, Matthias

Publication type:

Article

High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo.

Published in:

Life Science Alliance, 2021, v. 4, n. 11, p. 1, doi. 10.26508/lsa.202101034

By:

Bonekamp, Nina A.;
Min Jiang;
Motori, Elisa;
Villegas, Rodolfo Garcia;
Koolmeister, Camilla;
Atanassov, Ilian;
Mesaros, Andrea;
Chan Bae Park;
Larsson, Nils-Göran

Publication type:

Article

Down-Regulation of Mitochondrial Transcription Factor a During Spermatogenesis in Humans.

Published in:

Human Molecular Genetics, 1997, v. 6, n. 2, p. 185, doi. 10.1093/hmg/6.2.185

By:

Larsson, Nils-Göran;
Oldfors, Anders;
David Garman, J.;
Barsh, Gregory S.;
Clayton, David A.

Publication type:

Article

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03552-x

By:

Matic, Stanka;
Min Jiang;
Nicholls, Thomas J.;
Uhler, Jay P.;
Dirksen-Schwanenland, Caren;
Polosa, Paola Loguercio;
Simard, Marie-Lune;
Xinping Li;
Atanassov, Ilian;
Rackham, Oliver;
Filipovska, Aleksandra;
Stewart, James B.;
Falkenberg, Maria;
Larsson, Nils-Göran;
Milenkovic, Dusanka

Publication type:

Article

Secondary metabolic effects in complex I deficiency.

Published in:

Annals of Neurology, 2005, v. 58, n. 4, p. 544

By:

Nayla Esteitie;
Reetta Hinttala;
Rolf Wibom;
Helene Nilsson;
Nicole Hance;
Karin Naess;
Kristina Teär‐Fahnehjelm;
Ulrika Von Döbeln;
Kari Majamaa;
Nils‐Göran Larsson

Publication type:

Article

Leber hereditary optic neuropathy: A nuclear solution of a mitochondrial problem.

Published in:

Annals of Neurology, 2002, v. 52, n. 5, p. 529, doi. 10.1002/ana.10387

By:

Larsson, Nils-Göran

Publication type:

Article

Leber's hereditary optic neuropathy and complex I deficiency in muscle.

Published in:

Annals of Neurology, 1991, v. 30, n. 5, p. 701, doi. 10.1002/ana.410300511

By:

Larsson, Nils-Göran;
Andersen, Oluf;
Holme, Elisabeth;
Oldfors, Anders;
Wahlström, Jan

Publication type:

Article

Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA.

Published in:

PLoS Biology, 2008, v. 6, n. 1, p. e10, doi. 10.1371/journal.pbio.0060010

By:

Stewart, James Bruce;
Freyer, Christoph;
Elson, Joanna L.;
Wredenberg, Anna;
Cansu, Zekiye;
Trifunovic, Aleksandra;
Larsson, Nils-Göran

Publication type:

Article

Metabolic resistance to the inhibition of mitochondrial transcription revealed by CRISPR‐Cas9 screen.

Published in:

EMBO Reports, 2022, v. 23, n. 1, p. 1, doi. 10.15252/embr.202153054

By:

Mennuni, Mara;
Filograna, Roberta;
Felser, Andrea;
Bonekamp, Nina A;
Giavalisco, Patrick;
Lytovchenko, Oleksandr;
Larsson, Nils‐Göran

Publication type:

Article

TEFM regulates both transcription elongation and RNA processing in mitochondria.

Published in:

EMBO Reports, 2019, v. 20, n. 6, p. 1, doi. 10.15252/embr.201948101

By:

Jiang, Shan;
Koolmeister, Camilla;
Misic, Jelena;
Siira, Stefan;
Kühl, Inge;
Silva Ramos, Eduardo;
Miranda, Maria;
Jiang, Min;
Posse, Viktor;
Lytovchenko, Oleksandr;
Atanassov, Ilian;
Schober, Florian A;
Wibom, Rolf;
Hultenby, Kjell;
Milenkovic, Dusanka;
Gustafsson, Claes M;
Filipovska, Aleksandra;
Larsson, Nils‐Göran

Publication type:

Article

In vivo mutagenesis reveals that OriL is essential for mitochondrial DNA replication.

Published in:

EMBO Reports, 2012, v. 13, n. 12, p. 1130, doi. 10.1038/embor.2012.161

By:

Wanrooij, Sjoerd;
Miralles Fusté, Javier;
Stewart, James B;
Wanrooij, Paulina H;
Samuelsson, Tore;
Larsson, Nils-Göran;
Gustafsson, Claes M;
Falkenberg, Maria

Publication type:

Article

Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 22, p. 4827, doi. 10.1093/hmg/dds352

By:

Lee, Seungmin;
Sterky, Fredrik H.;
Mourier, Arnaud;
Terzioglu, Mügen;
Cullheim, Staffan;
Olson, Lars;
Larsson, Nils-Göran

Publication type:

Article

Altered dopamine metabolism and increased vulnerability to MPTP in mice with partial deficiency of mitochondrial complex I in dopamine neurons.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 5, p. 1078, doi. 10.1093/hmg/ddr537

By:

Sterky, Fredrik H.;
Hoffman, Alexander F.;
Milenkovic, Dusanka;
Bao, Betty;
Paganelli, Arianna;
Edgar, Daniel;
Wibom, Rolf;
Lupica, Carl R.;
Olson, Lars;
Larsson, Nils-Göran

Publication type:

Article

Sequence-specific stalling of DNA polymerase γ and the effects of mutations causing progressive ophthalmoplegia†.

Published in:

Human Molecular Genetics, 2011, v. 20, n. 6, p. 1212, doi. 10.1093/hmg/ddq565

By:

Atanassova, Neli;
Fusté, Javier Miralles;
Wanrooij, Sjoerd;
Macao, Bertil;
Goffart, Steffi;
Bäckström, Stefan;
Farge, Geraldine;
Khvorostov, Ivan;
Larsson, Nils-Göran;
Spelbrink, Johannes N.;
Falkenberg, Maria

Publication type:

Article

Increased mitochondrial Ca2+ and decreased sarcoplasmic reticulum Ca2+ in mitochondrial myopathy.

Published in:

Human Molecular Genetics, 2009, v. 18, n. 2, p. 278, doi. 10.1093/hmg/ddn355

By:

Aydin, Jan;
Andersson, Daniel C.;
Hänninen, Sandra L.;
Wredenberg, Anna;
Tavi, Pasi;
Park, Chan Bae;
Larsson, Nils-Göran;
Bruton, Joseph D.;
Westerblad, Håkan

Publication type:

Article

Age-associated mosaic respiratory chain deficiency causes trans-neuronal degeneration.

Published in:

Human Molecular Genetics, 2008, v. 17, n. 10, p. 1418, doi. 10.1093/hmg/ddn030

By:

Dufour, Eric;
Terzioglu, Mügen;
Sterky, Fredrik Hansson;
Sörensen, Lene;
Galter, Dagmar;
Olson, Lars;
Wilbertz, Johannes;
Larsson, Nils-Göran

Publication type:

Article

Abnormal Ca2+ release and catecholamine-induced arrhythmias in mitochondrial cardiomyopathy.

Published in:

Human Molecular Genetics, 2005, v. 14, n. 8, p. 1069, doi. 10.1093/hmg/ddi119

By:

Tavi, Pasi;
Hansson, Anna;
Zhang, Shi-Jin;
Larsson, Nils-Göran;
Westerblad, Håkan

Publication type:

Article

Mitochondrial transcription factor A regulates mtDNA copy number in mammals.

Published in:

Human Molecular Genetics, 2004, v. 13, n. 9, p. 935, doi. 10.1093/hmg/ddh109

By:

Ekstrand, Mats I.;
Falkenberg, Maria;
Rantanen, Anja;
Park, Chan Bae;
Gaspari, Martina;
Hultenby, Kjell;
Rustin, Pierre;
Gustafsson, Claes M.;
Larsson, Nils-Göran

Publication type:

Article

A role for BCL2L13 and autophagy in germline purifying selection of mtDNA.

Published in:

PLoS Genetics, 2023, v. 18, n. 1, p. 1, doi. 10.1371/journal.pgen.1010573

By:

Kremer, Laura S.;
Bozhilova, Lyuba V.;
Rubalcava-Gracia, Diana;
Filograna, Roberta;
Upadhyay, Mamta;
Koolmeister, Camilla;
Chinnery, Patrick F.;
Larsson, Nils-Göran

Publication type:

Article

Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction.

Published in:

PLoS Genetics, 2022, v. 18, n. 5, p. 1, doi. 10.1371/journal.pgen.1010190

By:

Milenkovic, Dusanka;
Sanz-Moreno, Adrián;
Calzada-Wack, Julia;
Rathkolb, Birgit;
Veronica Amarie, Oana;
Gerlini, Raffaele;
Aguilar-Pimentel, Antonio;
Misic, Jelena;
Simard, Marie-Lune;
Wolf, Eckhard;
Fuchs, Helmut;
Gailus-Durner, Valerie;
de Angelis, Martin Hrabě;
Larsson, Nils-Göran

Publication type:

Article

Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response.

Published in:

PLoS Genetics, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.pgen.1009822

By:

Filograna, Roberta;
Lee, Seungmin;
Tiklova, Katarina;
Mennuni, Mara;
Jonsson, Viktor;
Ringnér, Markus;
Gillberg, Linda;
Sopova, Elena;
Shupliakov, Oleg;
Koolmeister, Camilla;
Olson, Lars;
Perlmann, Thomas;
Larsson, Nils-Göran

Publication type:

Article

Introduction: Biology of ageing.

Published in:

Journal of Internal Medicine, 2008, v. 263, n. 2, p. 114, doi. 10.1111/j.1365-2796.2007.01900.x

By:

Larsson, Nils-Göran

Publication type:

Article

Complex genetic counselling and prenatal analysis in a woman with external ophthalmoplegia and deleted mtDNA.

Published in:

Prenatal Diagnosis, 2000, v. 20, n. 5, p. 426, doi. 10.1002/(SICI)1097-0223(200005)20:5<426::AID-PD845>3.0.CO;2-K

By:

Graff, Caroline;
Wredenberg, Anna;
Silva, José P.;
Bui, The-Hung;
Borg, Kristian;
Larsson, Nils-Göran

Publication type:

Article

FBXL4 deficiency increases mitochondrial removal by autophagy.

Published in:

EMBO Molecular Medicine, 2020, v. 12, n. 7, p. 1, doi. 10.15252/emmm.201911659

By:

Alsina, David;
Lytovchenko, Oleksandr;
Schab, Aleksandra;
Atanassov, Ilian;
Schober, Florian A;
Jiang, Min;
Koolmeister, Camilla;
Wedell, Anna;
Taylor, Robert W;
Wredenberg, Anna;
Larsson, Nils‐Göran

Publication type:

Article

Characterization of the mouse genes for mitochondrial transcription factors B1 and B2.

Published in:

Mammalian Genome, 2003, v. 14, n. 1, p. 1, doi. 10.1007/s00335-002-2218-z

By:

Rantanen, Anja;
Gaspari, Martina;
Falkenberg, Maria;
Gustafsson, Claes M.;
Larsson, Nils-Göran

Publication type:

Article