Works by Nijmeijer, Bart A.

Results: 9

The non-selective Rho-kinase inhibitors Y-27632 and Y-33075 decrease contraction but increase migration in murine and human hepatic stellate cells.

Published in:

PLoS ONE, 2023, v. 18, n. 1, p. 1, doi. 10.1371/journal.pone.0270288

By:

Bachtler, Nadine;
Torres, Sandra;
Ortiz, Cristina;
Schierwagen, Robert;
Tyc, Olaf;
Hieber, Christoph;
Berres, Marie-Luise;
Meier, Caroline;
Kraus, Nico;
Zeuzem, Stefan;
Nijmeijer, Bart;
Pronk, Sebas;
Trebicka, Jonel;
Klein, Sabine

Publication type:

Article

Titelbild: An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the PtII Linker Lx for Improved Manufacturability of Antibody–Drug Conjugates (Angew. Chem. 6/2021).

Published in:

Angewandte Chemie, 2021, v. 133, n. 6, p. 2741, doi. 10.1002/ange.202016966

By:

Merkul, Eugen;
Muns, Joey A.;
Sijbrandi, Niels J.;
Houthoff, Hendrik‐Jan;
Nijmeijer, Bart;
Rheenen, Gerro;
Reedijk, Jan;
Dongen, Guus A. M. S.

Publication type:

Article

An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the PtII Linker Lx for Improved Manufacturability of Antibody–Drug Conjugates.

Published in:

Angewandte Chemie, 2021, v. 133, n. 6, p. 3045, doi. 10.1002/ange.202011593

By:

Merkul, Eugen;
Muns, Joey A.;
Sijbrandi, Niels J.;
Houthoff, Hendrik‐Jan;
Nijmeijer, Bart;
Rheenen, Gerro;
Reedijk, Jan;
Dongen, Guus A. M. S.

Publication type:

Article

Complement-dependent cytotoxicity induced by therapeutic antibodies in B-cell acute lymphoblastic leukemia is dictated by target antigen expression levels and augmented by loss of membrane-bound complement inhibitors.

Published in:

Leukemia & Lymphoma, 2017, v. 58, n. 9, p. 2185, doi. 10.1080/10428194.2017.1281411

By:

Loeff, Floris C.;
van Egmond, H. M. Esther;
Nijmeijer, Bart A.;
Falkenburg, J. H. Frederik;
Halkes, Constantijn J.;
Jedema, Inge

Publication type:

Article

Preclinical targeting of liver fibrosis with a 89Zr-labeled Fibrobody® directed against platelet derived growth factor receptor-β.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2024, v. 51, n. 12, p. 3545, doi. 10.1007/s00259-024-06785-9

By:

Muns, Joey A.;
Schooten, Erik;
van Dasselaar, Rychon D. J.;
Noordman, Yvet E.;
Adamzek, Kevin;
Eibergen, Arthur C.;
Pronk, Sebas D.;
Cali, Sagel;
Sijbrandi, Niels J.;
Merkul, Eugen;
Oliveira, Sabrina;
van Bergen en Henegouwen, Paul M.P.;
Takkenberg, R. Bart;
Verheij, Joanne;
van de Graaf, Stan F.J.;
Nijmeijer, Bart A.;
van Dongen, Guus A.M.S.

Publication type:

Article

Cover Picture: An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the PtII Linker Lx for Improved Manufacturability of Antibody–Drug Conjugates (Angew. Chem. Int. Ed. 6/2021).

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 6, p. 2709, doi. 10.1002/anie.202016966

By:

Merkul, Eugen;
Muns, Joey A.;
Sijbrandi, Niels J.;
Houthoff, Hendrik‐Jan;
Nijmeijer, Bart;
Rheenen, Gerro;
Reedijk, Jan;
Dongen, Guus A. M. S.

Publication type:

Article

An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the PtII Linker Lx for Improved Manufacturability of Antibody–Drug Conjugates.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 6, p. 3008, doi. 10.1002/anie.202011593

By:

Merkul, Eugen;
Muns, Joey A.;
Sijbrandi, Niels J.;
Houthoff, Hendrik‐Jan;
Nijmeijer, Bart;
Rheenen, Gerro;
Reedijk, Jan;
Dongen, Guus A. M. S.

Publication type:

Article

First platinum(II)-based metal-organic linker technology (Lx®) for a plug-and-play development of antibody-drug conjugates (ADCs).

Published in:

Expert Opinion on Drug Delivery, 2019, v. 16, n. 8, p. 783, doi. 10.1080/17425247.2019.1645118

By:

Merkul, Eugen;
Sijbrandi, Niels J.;
Muns, Joey A.;
Aydin, Ibrahim;
Adamzek, Kevin;
Houthoff, Hendrik-Jan;
Nijmeijer, Bart;
Van Dongen, Guus A.M.S.

Publication type:

Article

Differential Effects of Selective Inhibitors Targeting the PI3K/AKT/mTOR Pathway in Acute Lymphoblastic Leukemia.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080070

By:

Badura, Susanne;
Tesanovic, Tamara;
Pfeifer, Heike;
Wystub, Sylvia;
Nijmeijer, Bart A.;
Liebermann, Marcus;
Falkenburg, J. H. Frederik;
Ruthardt, Martin;
Ottmann, Oliver G.

Publication type:

Article

Works by Nijmeijer, Bart A.

The non-selective Rho-kinase inhibitors Y-27632 and Y-33075 decrease contraction but increase migration in murine and human hepatic stellate cells.

Titelbild: An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the Pt<sup>II</sup> Linker Lx for Improved Manufacturability of Antibody–Drug Conjugates (Angew. Chem. 6/2021).

An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the Pt<sup>II</sup> Linker Lx for Improved Manufacturability of Antibody–Drug Conjugates.

Complement-dependent cytotoxicity induced by therapeutic antibodies in B-cell acute lymphoblastic leukemia is dictated by target antigen expression levels and augmented by loss of membrane-bound complement inhibitors.

Preclinical targeting of liver fibrosis with a <sup>89</sup>Zr-labeled Fibrobody® directed against platelet derived growth factor receptor-β.

Cover Picture: An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the Pt<sup>II</sup> Linker Lx for Improved Manufacturability of Antibody–Drug Conjugates (Angew. Chem. Int. Ed. 6/2021).

An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the Pt<sup>II</sup> Linker Lx for Improved Manufacturability of Antibody–Drug Conjugates.

First platinum(II)-based metal-organic linker technology (Lx®) for a plug-and-play development of antibody-drug conjugates (ADCs).

Differential Effects of Selective Inhibitors Targeting the PI3K/AKT/mTOR Pathway in Acute Lymphoblastic Leukemia.