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BRAF and MEK inhibitor combinations induce potent molecular and immunological effects in NRAS‐mutant melanoma cells: Insights into mode of action and resistance mechanisms.
- Published in:
- International Journal of Cancer, 2024, v. 154, n. 6, p. 1057, doi. 10.1002/ijc.34807
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- Publication type:
- Article
Augmenting MEK inhibitor efficacy in BRAF wild-type melanoma: synergistic effects of disulfiram combination therapy.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, n. 1, p. 1, doi. 10.1186/s13046-023-02941-5
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- Publication type:
- Article
Exploring the In Vitro and In Vivo Therapeutic Potential of BRAF and MEK Inhibitor Combination in NRAS-Mutated Melanoma.
- Published in:
- Cancers, 2023, v. 15, n. 23, p. 5521, doi. 10.3390/cancers15235521
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- Publication type:
- Article
Features and Long-Term Outcomes of Stage IV Melanoma Patients Achieving Complete Response Under Anti-PD-1-Based Immunotherapy.
- Published in:
- American Journal of Clinical Dermatology, 2023, v. 24, n. 3, p. 453, doi. 10.1007/s40257-023-00775-7
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- Publication type:
- Article
Relevant Membrane Transport Proteins as Possible Gatekeepers for Effective Pharmacological Ascorbate Treatment in Cancer.
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- Antioxidants, 2023, v. 12, n. 4, p. 916, doi. 10.3390/antiox12040916
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- Publication type:
- Article
High-Dose Ascorbate in Combination with Anti-PD1 Checkpoint Inhibition as Treatment Option for Malignant Melanoma.
- Published in:
- Cells (2073-4409), 2023, v. 12, n. 2, p. 254, doi. 10.3390/cells12020254
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- Publication type:
- Article
Pulmonary Surfactant Proteins Are Inhibited by Immunoglobulin A Autoantibodies in Severe COVID-19.
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- American Journal of Respiratory & Critical Care Medicine, 2023, v. 207, n. 1, p. 38, doi. 10.1164/rccm.202201-0011OC
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- Publication type:
- Article
Vitamin C Deficiency in Blood Samples of COVID-19 Patients.
- Published in:
- Antioxidants, 2022, v. 11, n. 8, p. N.PAG, doi. 10.3390/antiox11081580
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- Publication type:
- Article
Circulating tumor DNA (ctDNA) in the detection of relapse in melanoma patients with adjuvant anti‐PD‐1 therapy.
- Published in:
- Journal der Deutschen Dermatologischen Gesellschaft, 2022, v. 20, n. 6, p. 867, doi. 10.1111/ddg.14766
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- Publication type:
- Article
Zirkulierende Tumor‐DNA (ctDNA) bei der Entdeckung von Rezidiven bei Melanompatienten mit adjuvanter Anti‐PD‐1‐Therapie.
- Published in:
- Journal der Deutschen Dermatologischen Gesellschaft, 2022, v. 20, n. 6, p. 867, doi. 10.1111/ddg.14766_g
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- Publication type:
- Article
Individualized Proteogenomics Reveals the Mutational Landscape of Melanoma Patients in Response to Immunotherapy.
- Published in:
- Cancers, 2021, v. 13, n. 21, p. 5411, doi. 10.3390/cancers13215411
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- Publication type:
- Article
Comparative Analysis of the Antitumor Activity of Cis- and Trans-Resveratrol in Human Cancer Cells with Different p53 Status.
- Published in:
- Molecules, 2021, v. 26, n. 18, p. 5586, doi. 10.3390/molecules26185586
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- Publication type:
- Article
Ex Vivo Evaluation of the Sepsis Triple Therapy High-Dose Vitamin C in Combination with Vitamin B1 and Hydrocortisone in a Human Peripheral Blood Mononuclear Cells (PBMCs) Model.
- Published in:
- Nutrients, 2021, v. 13, n. 7, p. 2366, doi. 10.3390/nu13072366
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- Publication type:
- Article
Case Report: Combined CDK4/6 and MEK Inhibition in Refractory CDKN2A and NRAS Mutant Melanoma.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.643156
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- Publication type:
- Article
Disulfiram as a Therapeutic Agent for Metastatic Malignant Melanoma—Old Myth or New Logos?
- Published in:
- Cancers, 2020, v. 12, n. 12, p. 3538, doi. 10.3390/cancers12123538
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- Publication type:
- Article
Distinct Mutation Patterns Reveal Melanoma Subtypes and Influence Immunotherapy Response in Advanced Melanoma Patients.
- Published in:
- Cancers, 2020, v. 12, n. 9, p. 2359, doi. 10.3390/cancers12092359
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- Publication type:
- Article
Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14987-6
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- Publication type:
- Article
MDM2, MDM4 and EGFR Amplifications and Hyperprogression in Metastatic Acral and Mucosal Melanoma.
- Published in:
- Cancers, 2020, v. 12, n. 3, p. 540, doi. 10.3390/cancers12030540
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- Publication type:
- Article
6- and 8-Prenylnaringenin, Novel Natural Histone Deacetylase Inhibitors Found in Hops, Exert Antitumor Activity on Melanoma Cells.
- Published in:
- Cellular Physiology & Biochemistry (Karger AG), 2018, v. 51, n. 2, p. 543, doi. 10.1159/000495275
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- Publication type:
- Article
6- and 8-Prenylnaringenin, Novel Natural Histone Deacetylase Inhibitors Found in Hops, Exert Antitumor Activity on Melanoma Cells.
- Published in:
- Cellular Physiology & Biochemistry (Karger AG), 2018, v. 51, n. 2, p. 543, doi. 10.1159/000495275
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- Publication type:
- Article
Melanoma cells resistant towards MAPK inhibitors exhibit reduced TAp73 expression mediating enhanced sensitivity to platinum-based drugs.
- Published in:
- Cell Death & Disease, 2018, v. 9, n. 9, p. 1, doi. 10.1038/s41419-018-0952-8
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- Publication type:
- Article
Wnt-signaling enhances neural crest migration of melanoma cells and induces an invasive phenotype.
- Published in:
- Molecular Cancer, 2018, v. 17, p. 1, doi. 10.1186/s12943-018-0773-5
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- Publication type:
- Article
Combined activity of temozolomide and the mTOR inhibitor temsirolimus in metastatic melanoma involves DKK1.
- Published in:
- Experimental Dermatology, 2017, v. 26, n. 7, p. 598, doi. 10.1111/exd.13372
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- Publication type:
- Article
Molecular insights into melanoma brain metastases.
- Published in:
- 2017
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- Publication type:
- journal article
PTEN regulates IGF-1R-mediated therapy resistance in melanoma.
- Published in:
- Pigment Cell & Melanoma Research, 2015, v. 28, n. 5, p. 572, doi. 10.1111/pcmr.12390
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- Publication type:
- Article
Epigenetic impacts of ascorbate on human metastatic melanoma cells.
- Published in:
- Frontiers in Oncology, 2014, v. 4, p. 1, doi. 10.3389/fonc.2014.00227
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- Publication type:
- Article
Successful Treatment With Vemurafenib in BRAF V600K-Positive Cerebral Melanoma Metastasis.
- Published in:
- JAMA Dermatology, 2013, v. 149, n. 5, p. 642, doi. 10.1001/jamadermatol.2013.372
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- Publication type:
- Article
T-helper-1-cell cytokines drive cancer into senescence.
- Published in:
- Nature, 2013, v. 494, n. 7437, p. 361, doi. 10.1038/nature11824
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- Publication type:
- Article
Vemurafenib Potently Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in BRAFV600E Melanoma Cells.
- Published in:
- Science Signaling, 2013, v. 6, n. 260, p. 1, doi. 10.1126/scisignal.2003057
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- Publication type:
- Article
Cytotoxicity of new duplex drugs linking 3′-C-ethynylcytidine and 5-fluor-2′-deoxyuridine against human melanoma cells.
- Published in:
- International Journal of Cancer, 2012, v. 131, n. 9, p. 2165, doi. 10.1002/ijc.27476
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- Publication type:
- Article
The Farnesyl Transferase Inhibitor Lonafarnib Inhibits mTOR Signaling and Enforces Sorafenib-Induced Apoptosis in Melanoma Cells.
- Published in:
- Journal of Investigative Dermatology, 2011, v. 131, n. 2, p. 468, doi. 10.1038/jid.2010.297
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- Publication type:
- Article
Inhibition of PI3K-AKT-mTOR Signaling Sensitizes Melanoma Cells to Cisplatin and Temozolomide.
- Published in:
- Journal of Investigative Dermatology, 2009, v. 129, n. 6, p. 1500, doi. 10.1038/jid.2008.379
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- Publication type:
- Article