Works matching AU Nierhaus, Knud H.

Results: 51

EF-G and EF4: translocation and back-translocation on the bacterial ribosome.

Published in:

Nature Reviews Microbiology, 2014, v. 12, n. 2, p. 89, doi. 10.1038/nrmicro3176

By:

Yamamoto, Hiroshi;
Qin, Yan;
Achenbach, John;
Li, Chengmin;
Kijek, Jaroslaw;
Spahn, Christian M. T.;
Nierhaus, Knud H.

Publication type:

Article

Unusual Features of the Unusual Ribosomal Elongation Factor EF4 (LepA).

Published in:

Israel Journal of Chemistry, 2010, v. 50, n. 1, p. 117, doi. 10.1002/ijch.201000008

By:

Pech, Markus;
Yamamoto, Hiroshi;
Karim, Zhala;
Nierhaus, Knud H.

Publication type:

Article

Ribosomal protein L2 is involved in the association of the ribosomal subunits, tRNA binding to A and P sites and peptidyl transfer.

Published in:

EMBO Journal, 2000, v. 19, n. 19, p. 5241, doi. 10.1093/emboj/19.19.5241

By:

Diedrich, Gundo;
Spahn, Christian M. T.;
Stelzl, Ulrich;
Schäfer, Markus A.;
Wooten, Tammy;
Bochkariov, Dmirty E.;
Cooperman, Barry S.;
Traut, Robert R.;
Nierhaus, Knud H.

Publication type:

Article

Hsp15: a ribosome-associated heat shock protein.

Published in:

EMBO Journal, 2000, v. 19, n. 4, p. 741, doi. 10.1093/emboj/19.4.741

By:

Korber, Philipp;
Stahl, Jennifer M.;
Nierhaus, Knud H.;
Bardwell, James C. A.

Publication type:

Article

The tetracycline resistance protein Tet(○) perturbs the conformation of the ribosomal decoding centre.

Published in:

Molecular Microbiology, 2002, v. 45, n. 6, p. 1463, doi. 10.1046/j.1365-2958.2002.03115.x

By:

Connell, Sean R.;
Trieber, Catharine A.;
Stelzl, Ulrich;
Einfeldt, Edda;
Taylor, Diane E.;
Nierhaus, Knud H.

Publication type:

Article

Common chaperone activity in the G-domain of trGTPase protects L11–L12 interaction on the ribosome.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 21, p. 10851, doi. 10.1093/nar/gks833

By:

Zhang, Dandan;
Liu, Guangqiao;
Xue, Jiaying;
Lou, Jizhong;
Nierhaus, Knud H.;
Gong, Weimin;
Qin, Yan

Publication type:

Article

Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 12, p. 5264, doi. 10.1093/nar/gkr114

By:

Muhs, Margarita;
Yamamoto, Hiroshi;
Ismer, Jochen;
Takaku, Hiroaki;
Nashimoto, Masayuki;
Uchiumi, Toshio;
Nakashima, Nobuhiko;
Mielke, Thorsten;
Hildebrand, Peter W.;
Nierhaus, Knud H.;
Spahn, Christian M. T.

Publication type:

Article

Features of 80S mammalian ribosome and its subunits.

Published in:

Nucleic Acids Research, 2008, v. 36, n. 14, p. 4736, doi. 10.1093/nar/gkn424

By:

Budkevich, Tatyana V.;
El'skaya, Anna V.;
Nierhaus, Knud H.

Publication type:

Article

Troubleshooting coupled in vitro transcription–translation system derived from Escherichia coli cells: synthesis of high-yield fully active proteins.

Published in:

Nucleic Acids Research, 2006, v. 34, n. 19, p. e135, doi. 10.1093/nar/gkl462

By:

Iskakova, Madina B.;
Szaflarski, Witold;
Dreyfus, Marc;
Remme, Jaanus;
Nierhaus, Knud H.

Publication type:

Article

Deacylated tRNA is released from the E site upon A site occupation but before GTP is hydrolyzed by EF-Tu.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 16, p. 5291, doi. 10.1093/nar/gki833

By:

Dinos, George;
Kalpaxis, Dimitrios L.;
Wilson, Daniel N.;
Nierhaus, Knud H.

Publication type:

Article

Mapping of the second tetracycline binding site on the ribosomal small subunit of E.coli.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 8, p. 2594, doi. 10.1093/nar/gkh583

By:

Anokhina, Maria M.;
Barta, Andrea;
Nierhaus, Knud H.;
Spiridonova, Vera A.;
Kopylov, Alexei M.

Publication type:

Article

Response to the Formal Letter of Z. Chrzanowska-Lightowlers and R. N. Lightowlers Regarding Our Article “Ribosome Rescue and Translation Termination at Non-Standard Stop Codons by ICT1 in Mammalian Mitochondria”.

Published in:

2015

By:

Takeuchi, Nono;
Nierhaus, Knud H.

Publication type:

Letter to the Editor

Ribosome Rescue and Translation Termination at Non-Standard Stop Codons by ICT1 in Mammalian Mitochondria.

Published in:

PLoS Genetics, 2014, v. 10, n. 9, p. 1, doi. 10.1371/journal.pgen.1004616

By:

Akabane, Shiori;
Ueda, Takuya;
Nierhaus, Knud H.;
Takeuchi, Nono

Publication type:

Article

RsfA (YbeB) Proteins Are Conserved Ribosomal Silencing Factors.

Published in:

PLoS Genetics, 2012, v. 8, n. 7, p. 1, doi. 10.1371/journal.pgen.1002815

By:

Häuser, Roman;
Pech, Markus;
Kijek, Jaroslaw;
Yamamoto, Hiroshi;
Titz, Björn;
Naeve, Florian;
Tovchigrechko, Andrey;
Yamamoto, Kaori;
Szaflarski, Witold;
Takeuchi, Nono;
Stellberger, Thorsten;
Diefenbacher, Markus E.;
Nierhaus, Knud H.;
Uetz, Peter

Publication type:

Article

Species-specific antibiotic-ribosome interactions: implications for drug development.

Published in:

Biological Chemistry, 2005, v. 386, n. 12, p. 1239, doi. 10.1515/BC.2005.141

By:

Wilson, Daniel N.;
Harms, Jörg M.;
Nierhaus, Knud H.;
Schlünzen, Frank;
Fucini, Paola

Publication type:

Article

Das Ribosom unter der Lupe.

Published in:

Angewandte Chemie, 2003, v. 115, n. 30, p. 3586, doi. 10.1002/ange.200200544

By:

Daniel N. Wilson;
Knud H. Nierhaus

Publication type:

Article

The ribosome: still a knotty problem.

Published in:

Nature, 1978, v. 274, n. 5673, p. 743, doi. 10.1038/274743b0

By:

Nierhaus, Knud H.

Publication type:

Article

Ribosome Assembly as Antimicrobial Target.

Published in:

Antibiotics (2079-6382), 2016, v. 5, n. 2, p. 18, doi. 10.3390/antibiotics5020018

By:

Nikolay, Rainer;
Schmidt, Sabine;
Schlömer, Renate;
Deuerling, Elke;
Nierhaus, Knud H.

Publication type:

Article

Nobel Prize for the Elucidation of Ribosome Structure and Insight into the Translation Mechanism.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 49, p. 9225, doi. 10.1002/anie.200905795

By:

Nierhaus, Knud H.

Publication type:

Article

Fast Biosynthesis of GFP Molecules: A Single-Molecule Fluorescence Study.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 10, p. 1758, doi. 10.1002/anie.200806070

By:

Katranidis, Alexandros;
Atta, Diaa;
Schlesinger, Ramona;
Nierhaus, Knud H.;
Choli-Papadopoulou, Theodora;
Gregor, Ingo;
Gerrits, Michael;
Büldt, Georg;
Fitter, Jörg

Publication type:

Article

Interaction of mRNA with the Escherichia coli ribosome: accessibility of phosphorothioate-containing mRNA bound to ribosomes for iodine cleavage.

Published in:

Nucleic Acids Research, 1996, v. 24, n. 12, p. 2228, doi. 10.1093/nar/24.12.2228

By:

Alexeeva, Ekaterina V.;
Shpanchenko, Olga V.;
Dontsova, Olga A.;
Bogdanov, Alexey A.;
Nierhaus, Knud H.

Publication type:

Article

Effects of Antisense DNA Against the α-Sarcin Stem-Loop Structure of the Ribosomal 23S rRNA.

Published in:

Nucleic Acids Research, 1996, v. 24, n. 20, p. 3996, doi. 10.1093/nar/24.20.3996

By:

Meyer, Hellmuth-Alexander;
Triana-Alonso, Francisco;
Spahn, Christian M. T.;
Twardowski, Tomasz;
Sobkiewicz, Andrzej;
Nierhaus, Knud H.

Publication type:

Article

In Vivo Deuteration of Transfer RNAs: Overexpression and Large-Scale Purification of Deuterated Specific tRNAs.

Published in:

Nucleic Acids Research, 1996, v. 24, n. 5, p. 907, doi. 10.1093/nar/24.5.907

By:

Jünemann, Ralf;
Wadzack, Jörg;
Triana-Alonso, Francisco J.;
Bittner, Jörg-Uwe;
Caillet, Joël;
Meinnel, Thierry;
Vanatalu, Kalju;
Nierhaus, Knud H.

Publication type:

Article

In situ structure determination of the ribosomal protein L14 in the large 50S subunit of Escherichia coli.

Published in:

Journal of Applied Crystallography, 2000, v. 33, n. 3, p. 524, doi. 10.1107/S0021889800097995

By:

Forthmann, Stefan;
Diedrich, Gundo;
Nierhaus, Knud H.;
Willumeit, Regine

Publication type:

Article

Lys53 of Ribosomal Protein L36AL and the CCA End of a tRNA at the P/E Hybrid Site Are in Close Proximity on the Human Ribosome.

Published in:

ChemBioChem, 2012, v. 13, n. 12, p. 1791, doi. 10.1002/cbic.201200208

By:

Hountondji, Codjo;
Bulygin, Konstantin;
Woisard, Anne;
Tuffery, Pierre;
Créchet, Jean-Bernard;
Pech, Markus;
Nierhaus, Knud H.;
Karpova, Galina;
Baouz, Soria

Publication type:

Article

The Thorny Way to the Mechanism of Ribosomal Peptide-Bond Formation.

Published in:

ChemBioChem, 2012, v. 13, n. 2, p. 189, doi. 10.1002/cbic.201100660

By:

Pech, Markus;
Nierhaus, Knud H.

Publication type:

Article

Translational Termination Not Yet at Its End.

Published in:

ChemBioChem, 2000, v. 1, n. 4, p. 250, doi. 10.1002/1439-7633(20001117)1:4<250::AID-CBIC250>3.0.CO;2-B

By:

Connell, Sean R.;
Nierhaus, Knud H.

Publication type:

Article

An elongation factor turn-on.

Published in:

Nature, 1996, v. 379, n. 6565, p. 491, doi. 10.1038/379491a0

By:

Nierhaus, Knud H.

Publication type:

Article

Three mechanisms in Escherichia coli rescue ribosomes stalled on non-stop mRNAs: one of them requires release factor 2.

Published in:

Molecular Microbiology, 2012, v. 86, n. 1, p. 6, doi. 10.1111/j.1365-2958.2012.08207.x

By:

Pech, Markus;
Nierhaus, Knud H.

Publication type:

Article

The Ribosome through the Looking Glass.

Published in:

Angewandte Chemie International Edition, 2003, v. 42, n. 30, p. 3464, doi. 10.1002/anie.200200544

By:

Daniel N. Wilson;
Knud H. Nierhaus

Publication type:

Article

Outwitting EF-Tu and the ribosome: translation with D-amino acids.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 12, p. 5687, doi. 10.1093/nar/gkv566

By:

Achenbach, John;
Jahnz, Michael;
Bethge, Lucas;
Paal, Krisztina;
Jung, Maria;
Schuster, Maja;
Albrecht, Renate;
Jarosch, Florian;
Nierhaus, Knud H.;
Klussmann, Sven

Publication type:

Article

The Tricks of Ribosomal Elongation Factors.

Published in:

Angewandte Chemie International Edition, 1996, v. 35, n. 19, p. 2198, doi. 10.1002/anie.199621981

By:

Nierhaus, Knud H.

Publication type:

Article

A dedicated translation factor controls the synthesis of the global regulator Fis.

Published in:

2007

By:

Owens, Róisín M.;
Pritchard, Gareth;
Skipp, Paul;
Hodey, Michelle;
Connell, Sean R.;
Nierhaus, Knud H.;
O'Connor, C. David

Publication type:

Correction Notice

A dedicated translation factor controls the synthesis of the global regulator Fis.

Published in:

EMBO Journal, 2004, v. 23, n. 16, p. 3375, doi. 10.1038/sj.emboj.7600343

By:

Owens, Róisín M.;
Pritchard, Gareth;
Skipp, Paul;
Hodey, Michelle;
Connell, Sean R.;
Nierhaus, Knud H.;
O'Connor, C. David

Publication type:

Article

Mechanism of Tet(O)-mediated tetracycline resistance.

Published in:

EMBO Journal, 2003, v. 22, n. 4, p. 945, doi. 10.1093/emboj/cdg093

By:

Connell, Sean R.;
Trieber, Catharine A.;
Dinos, George P.;
Einfeldt, Edda;
Taylor, Diane E.;
Nierhaus, Knud H.

Publication type:

Article

Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.

Published in:

EMBO Journal, 2002, v. 21, n. 13, p. 3557, doi. 10.1093/emboj/cdf326

By:

Valle, Mikel;
Sengupta, Jayati;
Swami, Neil K.;
Grassucci, Robert A.;
Burkhardt, Nils;
Nierhaus, Knud H.;
Agrawal, Rajendra K.;
Frank, Joachim

Publication type:

Article

EF-G catalyzes tRNA translocation by disrupting interactions between decoding center and codon-anticodon duplex.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 9, p. 817, doi. 10.1038/nsmb.2869

By:

Liu, Guangqiao;
Song, Guangtao;
Zhang, Danyang;
Zhang, Dejiu;
Li, Zhikai;
Lyu, Zhixin;
Dong, Jianshu;
Achenbach, John;
Gong, Weimin;
Zhao, Xin Sheng;
Nierhaus, Knud H;
Qin, Yan

Publication type:

Article

Translocation at work.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 9, p. 1019, doi. 10.1038/nsmb.2661

By:

Achenbach, John;
Nierhaus, Knud H

Publication type:

Article

A conserved proline switch on the ribosome facilitates the recruitment and binding of trGTPases.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 4, p. 403, doi. 10.1038/nsmb.2254

By:

Wang, Li;
Yang, Fang;
Zhang, Dejiu;
Chen, Zhi;
Xu, Rui-Ming;
Nierhaus, Knud H;
Gong, Weimin;
Qin, Yan

Publication type:

Article

A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 9, p. 910, doi. 10.1038/nsmb.1469

By:

Connell, Sean R.;
Topf, Maya;
Yan Qin;
Wilson, Daniel N.;
Mielke, Thorsten;
Fucini, Paola;
Nierhaus, Knud H.;
Spahn, Christian M. T.

Publication type:

Article

Erratum: The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.

Published in:

2006

By:

Schluenzen, Frank;
Takemoto, Chie;
Wilson, Daniel N.;
Kaminishi, Tatsuya;
Harms, Joerg M.;
Hanawa-Suetsugu, Kyoko;
Szaflarski, Witold;
Kawazoe, Masahito;
Shirouzu, Mikako;
Nierhaus, Knud H.;
Yokoyama, Shigeyuki;
Fucini, Paola

Publication type:

Correction Notice

The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 10, p. 871, doi. 10.1038/nsmb1145

By:

Schluenzen, Frank;
Takemoto, Chie;
Wilson, Daniel N.;
Kaminishi, Tatsuya;
Harms, Joerg M.;
Hanawa-Suetsugu, Kyoko;
Szaflarski, Witold;
Kawazoe, Masahito;
Shirouzo, Mikako;
Nierhaus, Knud H.;
Yokoyama, Shigeyuki;
Fucini, Paola

Publication type:

Article

RelBE or not to be.

Published in:

Nature Structural & Molecular Biology, 2005, v. 12, n. 4, p. 282, doi. 10.1038/nsmb0405-282

By:

Wilson, Daniel N;
Nierhaus, Knud H

Publication type:

Article

The how and Y of cold shock.

Published in:

Nature Structural & Molecular Biology, 2004, v. 11, n. 11, p. 1026, doi. 10.1038/nsmb1104-1026

By:

Wilson, Daniel N.;
Nierhaus, Knud H.

Publication type:

Article

Solution of the ribosome riddle: how the ribosome selects the correct aminoacyl-tRNA out of 41 similar contestants.

Published in:

Molecular Microbiology, 1993, v. 9, n. 4, p. 661, doi. 10.1111/j.1365-2958.1993.tb01726.x

By:

Nierhaus, Knud H.

Publication type:

Article

The complex of tmRNA-SmpB and EF-G on translocating ribosomes.

Published in:

Nature, 2012, v. 485, n. 7399, p. 526, doi. 10.1038/nature11006

By:

Ramrath, David J. F.;
Yamamoto, Hiroshi;
Rother, Kristian;
Wittek, Daniela;
Pech, Markus;
Mielke, Thorsten;
Loerke, Justus;
Scheerer, Patrick;
Ivanov, Pavel;
Teraoka, Yoshika;
Shpanchenko, Olga;
Nierhaus, Knud H.;
Spahn, Christian M. T.

Publication type:

Article

Biophysical study of a molecular intermediate preceding collapse of tight couple and Kaltschmidt–Wittmann ribosomes

Published in:

FEBS Letters, 2002, v. 525, n. 1-3, p. 111, doi. 10.1016/S0014-5793(02)03098-3

By:

Bonincontro, Adalberto;
Nierhaus, Knud H.;
Ortore, Maria Grazia;
Risuleo, Gianfranco

Publication type:

Article

How does tmRNA move through the ribosome?

Published in:

FEBS Letters, 2002, v. 514, n. 1, p. 55, doi. 10.1016/S0014-5793(02)02310-4

By:

Ivanov, Pavel V.;
Zvereva, Maria I.;
Shpanchenko, Olga V.;
Dontsova, Olga A.;
Bogdanov, Alexey A.;
Aglyamova, Galina V.;
Lim, Valery I.;
Teraoka, Yoshika;
Nierhaus, Knud H.

Publication type:

Article

The Weird and Wonderful World of Bacterial Ribosome Regulation.

Published in:

Critical Reviews in Biochemistry & Molecular Biology, 2007, v. 42, n. 3, p. 187, doi. 10.1080/10409230701360843

By:

Wilson, Daniel N.;
Nierhaus, Knud H.

Publication type:

Article

Ribosomal Proteins in the Spotlight.

Published in:

Critical Reviews in Biochemistry & Molecular Biology, 2005, v. 40, n. 5, p. 243, doi. 10.1080/10409230500256523

By:

Wilson, Daniel N.;
Nierhaus, Knud H.

Publication type:

Article