Works by Nienow, Alvin W.

Results: 51

Performance of the scaba 6SRGT agitator in mixing of simulated xanthan gum broths.

Published in:

Chemical Engineering & Technology, 1993, v. 16, n. 2, p. 102, doi. 10.1002/ceat.270160206

By:

Galindo, Enrique;
Nienow, Alvin W.

Publication type:

Article

Design and development of a new ambr250® bioreactor vessel for improved cell and gene therapy applications.

Published in:

Biotechnology Letters, 2021, v. 43, n. 5, p. 1103, doi. 10.1007/s10529-021-03076-3

By:

Rotondi, Marco;
Grace, Ned;
Betts, John;
Bargh, Neil;
Costariol, Elena;
Zoro, Barney;
Hewitt, Christopher J.;
Nienow, Alvin W.;
Rafiq, Qasim A.

Publication type:

Article

Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum-free microcarrier process.

Published in:

Biotechnology & Bioengineering, 2015, v. 112, n. 8, p. 1696, doi. 10.1002/bit.25582

By:

Heathman, Thomas R. J.;
Glyn, Veronica A. M.;
Picken, Andrew;
Rafiq, Qasim A.;
Coopman, Karen;
Nienow, Alvin W.;
Kara, Bo;
Hewitt, Christopher J.

Publication type:

Article

A comparison of high cell density fed-batch fermentations involving both induced and non-induced recombinant Escherichia coli under well-mixed small-scale and simulated poorly mixed large-scale conditions.

Published in:

Biotechnology & Bioengineering, 2007, v. 96, n. 3, p. 495, doi. 10.1002/bit.21127

By:

Hewitt, Christopher J.;
Onyeaka, Helen;
Lewis, Gareth;
Taylor, Ian W.;
Nienow, Alvin W.

Publication type:

Article

Further studies related to the scale-up of high cell density escherichia coli fed-batch fermentations.

Published in:

Biotechnology & Bioengineering, 2003, v. 84, n. 4, p. 474, doi. 10.1002/bit.10805

By:

Helen Onyeaka;
Alvin W. Nienow;
Christopher J. Hewitt

Publication type:

Article

Scale‐up of an intensified bioprocess for the expansion of bovine adipose‐derived stem cells (bASCs) in stirred tank bioreactors.

Published in:

Biotechnology & Bioengineering, 2021, v. 118, n. 8, p. 3175, doi. 10.1002/bit.27842

By:

Hanga, Mariana Petronela;
Raga, Fritz Anthony;
Moutsatsou, Panagiota;
Hewitt, Christopher J.;
Nienow, Alvin W.;
Wall, Ivan

Publication type:

Article

Establishing the scalable manufacture of primary human T‐cells in an automated stirred‐tank bioreactor.

Published in:

Biotechnology & Bioengineering, 2019, v. 116, n. 10, p. 2488, doi. 10.1002/bit.27088

By:

Costariol, Elena;
Rotondi, Marco;
Amini, Arman;
Hewitt, Christopher J.;
Nienow, Alvin W.;
Heathman, Thomas R.J.;
Micheletti, Martina;
Rafiq, Qasim A.

Publication type:

Article

Process development of human multipotent stromal cell microcarrier culture using an automated high-throughput microbioreactor.

Published in:

Biotechnology & Bioengineering, 2017, v. 114, n. 10, p. 2253, doi. 10.1002/bit.26359

By:

Rafiq, Qasim A.;
Hanga, Mariana P.;
Heathman, Thomas R. J.;
Coopman, Karen;
Nienow, Alvin W.;
Williams, David J.;
Hewitt, Christopher J.

Publication type:

Article

Lagrangian tools for the analysis of mixing in single-phase and multiphase flow systems.

Published in:

AIChE Journal, 2012, v. 58, n. 1, p. 31, doi. 10.1002/aic.12557

By:

Guida, Antonio;
Nienow, Alvin W.;
Barigou, Mostafa

Publication type:

Article

Mixing of dense binary suspensions: Multi-component hydrodynamics and spatial phase distribution by PEPT.

Published in:

AIChE Journal, 2011, v. 57, n. 9, p. 2302, doi. 10.1002/aic.12456

By:

Guida, Antonio;
Nienow, Alvin W.;
Barigou, Mostafa

Publication type:

Article

The Impact of Fluid Dynamic Stress in Stirred Bioreactors – The Scale of the Biological Entity: A Personal View.

Published in:

Chemie Ingenieur Technik (CIT), 2021, v. 93, n. 1/2, p. 17, doi. 10.1002/cite.202000176

By:

Nienow, Alvin W.

Publication type:

Article

Stirring and Stirred-Tank Reactors.

Published in:

Chemie Ingenieur Technik (CIT), 2014, v. 86, n. 12, p. 2063, doi. 10.1002/cite.201400087

By:

Nienow, Alvin W.

Publication type:

Article

Studies related to the scale-up of high-cell-density E. coli fed-batch fermentations using multiparameter flow cytometry: Effect of a changing microenvironment with respect to glucose and dissolved oxygen concentration.

Published in:

Biotechnology & Bioengineering, 2000, v. 70, n. 4, p. 381, doi. 10.1002/1097-0290(20001120)70:4<381::AID-BIT3>3.0.CO;2-0

By:

Hewitt, Christopher J.;
Nebe-Von Caron, Gerhard;
Axelsson, Britta;
McFarlane, Caroline M.;
Nienow, Alvin W.

Publication type:

Article

Study of drop and bubble sizes in a simulated mycelial fermentation broth of up to four phases.

Published in:

Biotechnology & Bioengineering, 2000, v. 69, n. 2, p. 213, doi. 10.1002/(SICI)1097-0290(20000720)69:2<213::AID-BIT10>3.0.CO;2-D

By:

Galindo, Enrique;
Pacek, Andrzej W.;
Nienow, Alvin W.

Publication type:

Article

Control of pH in large-scale, free suspension animal cell bioreactors: Alkali addition and pH excursions.

Published in:

Biotechnology & Bioengineering, 1999, v. 66, n. 3, p. 171, doi. 10.1002/(SICI)1097-0290(1999)66:3<171::AID-BIT5>3.0.CO;2-T

By:

Langheinrich, Christian;
Nienow, Alvin W.

Publication type:

Article

Use of multi-staining flow cytometry to characterise the physiological state of Escherichia coli W3110 in high cell density fed-batch cultures.

Published in:

Biotechnology & Bioengineering, 1999, v. 63, n. 6, p. 705, doi. 10.1002/(SICI)1097-0290(19990620)63:6<705::AID-BIT8>3.0.CO;2-M

By:

Hewitt, Christopher J.;
Nebe-Von Caron, Gerhard;
Nienow, Alvin W.;
McFarlane, Caroline M.

Publication type:

Article

The use of flow cytometry to study the impact of fluid mechanical stress on Escherichia coli W3110 during continuous cultivation in an agitated bioreactor.

Published in:

Biotechnology & Bioengineering, 1998, v. 59, n. 5, p. 612, doi. 10.1002/(SICI)1097-0290(19980905)59:5<612::AID-BIT12>3.0.CO;2-B

By:

Hewitt, Christopher J.;
Boon, Lotte A.;
McFarlane, Caroline M.;
Nienow, Alvin W.

Publication type:

Article

Micromixing in two-phase (G-L and S-L) systems in a stirred vessel.

Published in:

Canadian Journal of Chemical Engineering, 2011, v. 89, n. 5, p. 1029, doi. 10.1002/cjce.20494

By:

Hofinger, Julia;
Sharpe, Robert W.;
Bujalski, Waldemar;
Bakalis, Serafim;
Assirelli, Melissa;
Eaglesham, Archie;
Nienow, Alvin W.

Publication type:

Article

Some Effects of Particle Wettability in Agitated Solid-Gas-Liquid Systems: Gas-Liquid Mass Transfer and the Dispersion of Floating Solids.

Published in:

Canadian Journal of Chemical Engineering, 2003, v. 81, n. 3/4, p. 581, doi. 10.1002/cjce.5450810333

By:

Gentile, Fabio;
Oleschko, Holger;
Veverka, Premek;
Machoň, Vaclav;
Paglianti, Alessandro;
Bujalski, Waldemar;
Etchells, Arthur W.;
Nienow, Alvin W.

Publication type:

Article

Instabilities when using a standard ( T/3) rushton turbine for stirring as foam disruption (SAFD).

Published in:

Canadian Journal of Chemical Engineering, 2000, v. 78, n. 5, p. 884, doi. 10.1002/cjce.5450780505

By:

Boon, Lotte A.;
Bujalski, Waldemar;
Nienow, Alvin W.;
Hoeks, Frans W.J.M.M.;
Van Der Lans, Rob G.J.M.

Publication type:

Article

Gas-liquid mixing studies with multiple up- and down-pumping hydrofoil impellers: Power characteristics and mixing time.

Published in:

Canadian Journal of Chemical Engineering, 1998, v. 76, n. 6, p. 1056, doi. 10.1002/cjce.5450760612

By:

Hari-Prajitno, Danawati;
Mishra, Ved P.;
Takenaka, Katsuhide;
Bujalski, Waldemar;
Nienow, Alvin W.;
Mckemmie, Jack

Publication type:

Article

A study of an up- and a down-pumping wide-blade hydrofoil impeller: Part II. CFD analysis.

Published in:

Canadian Journal of Chemical Engineering, 1998, v. 76, n. 5, p. 866, doi. 10.1002/cjce.5450760503

By:

Jaworski, Zdzislaw;
Dyster, Kate N.;
Mishra, Ved P.;
Nienow, Alvin W.;
Wyszynski, Miroslaw L.

Publication type:

Article

Ingénierie du mélange: État actuel de la recherche préambule.

Published in:

Canadian Journal of Chemical Engineering, 1998, v. 76, n. 3, p. 338, doi. 10.1002/cjce.5450760302

By:

Tanguy, Philippe A.;
Nienow, Alvin W.

Publication type:

Article

A study of an up- and a down-pumping wide blade hydrofoil impeller: Part I. LDA measurements.

Published in:

Canadian Journal of Chemical Engineering, 1998, v. 76, n. 3, p. 577, doi. 10.1002/cjce.5450760330

By:

Mishra, Ved P.;
Dyster, Kate N.;
Nienow, Alvin W.;
Mckemmie, Jack;
Jaworski, Zdzislaw

Publication type:

Article

Engineering research on mixing: State of the art introductory remarks.

Published in:

Canadian Journal of Chemical Engineering, 1998, v. 76, n. 3, p. 337, doi. 10.1002/cjce.5450760301

By:

Tanguy, Philippe A.;
Nienow, Alvin W.

Publication type:

Article

Scale-up of mixing in gassed multi-turbine agitated vessels.

Published in:

Canadian Journal of Chemical Engineering, 1998, v. 76, n. 3, p. 398, doi. 10.1002/cjce.5450760308

By:

Vasconcelos, Jorge M. T.;
Alves, Sebastião S.;
Nienow, Alvin W.;
Bujalski, Waldemar

Publication type:

Article

Demonstrating the Manufacture of Human CAR‐T Cells in an Automated Stirred‐Tank Bioreactor.

Published in:

Biotechnology Journal, 2020, v. 15, n. 9, p. 1, doi. 10.1002/biot.202000177

By:

Costariol, Elena;
Rotondi, Marco C.;
Amini, Arman;
Hewitt, Christopher J.;
Nienow, Alvin W.;
Heathman, Thomas R. J.;
Rafiq, Qasim A.

Publication type:

Article

Mixing of Highly Viscous Simulated Xanthan Fermentation Broths with the Lightnin A-315 Impeller.

Published in:

Biotechnology Progress, 1992, v. 8, n. 3, p. 233, doi. 10.1021/bp00015a009

By:

Galindot, Enrique;
Nienow, Alvin W.

Publication type:

Article

Studies supporting the use of mechanical mixing in large scale beer fermentations.

Published in:

Biotechnology Letters, 2010, v. 32, n. 5, p. 623, doi. 10.1007/s10529-010-0213-0

By:

Nienow, Alvin W.;
McLeod, Georgina;
Hewitt, Christopher J.

Publication type:

Article

The impact of fluid mechanical stress on Corynebacterium glutamicum during continuous cultivation in an agitated bioreactor.

Published in:

Biotechnology Letters, 2005, v. 27, n. 10, p. 693, doi. 10.1007/s10529-005-4690-5

By:

Chamsartra, Saethawat;
Hewitt, Christopher J.;
Nienow, Alvin W.

Publication type:

Article

Reproducibility of Pilot Scale Xanthan Fermentations.

Published in:

Biotechnology Progress, 1996, v. 12, n. 4, p. 466, doi. 10.1021/bp960042k

By:

Amanullah, Ashraf;
Serrano, Leobardo-Carreon;
Galindo, Enrique;
Nienow, Alvin W.

Publication type:

Article

Studies of High Solidity Ratio Hydrofoil Impellers for Aerated Bioreactors. 3. Fluids of Enhanced Viscosity and Exhibiting Coalescence Repression.

Published in:

Biotechnology Progress, 1996, v. 12, n. 1, p. 1, doi. 10.1021/bp950033w

By:

McFarlane, Caroline M.;
Nienow, Alvin W.

Publication type:

Article

Studies of High Solidity Ratio Hydrofoil Impellers for Aerated Bioreactors. 4. Comparison of Impeller Types.

Published in:

Biotechnology Progress, 1996, v. 12, n. 1, p. 9, doi. 10.1021/bp950034o

By:

McFarlane, Caroline M.;
Nienow, Alvin W.

Publication type:

Article

Studies of High Solidity Ratio Hydrofoil Impellers for Aerated Bioreactors. 1. Review.

Published in:

Biotechnology Progress, 1995, v. 11, n. 6, p. 601, doi. 10.1021/bp00036a001

By:

Mcfarlane, Caroline M.;
Nienow, Alvin W.

Publication type:

Article

Studies of High Solidity Ratio Hydrofoil Impellers for Aerated Bioreactors. 2. Air-Water Studies.

Published in:

Biotechnology Progress, 1995, v. 11, n. 6, p. 608, doi. 10.1021/bp00036a002

By:

Mcfarlane, Caroline M.;
Zhao, Xue -Ming;
Nienow, Alvin W.

Publication type:

Article

Ein neuer, axial fördernder Rührer zum Dispergieren von Gas in Flüssigkeiten.

Published in:

Chemie Ingenieur Technik (CIT), 1989, v. 61, n. 2, p. 152, doi. 10.1002/cite.330610213

By:

Haß, Volker C.;
Nienow, Alvin W.

Publication type:

Article

Fabrication by three-phase emulsification of pellicular adsorbents customised for liquid fluidised bed adsorption of bioproducts.

Published in:

Journal of Chemical Technology & Biotechnology, 2003, v. 78, n. 11, p. 1111, doi. 10.1002/jctb.907

By:

Mohsen Jahanshahi;
Andrzej W Pacek;
Alvin W Nienow;
Andrew Lyddiatt

Publication type:

Article

Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors.

Published in:

Biotechnology Journal, 2016, v. 11, n. 4, p. 473, doi. 10.1002/biot.201400862

By:

Rafiq, Qasim A.;
Coopman, Karen;
Nienow, Alvin W.;
Hewitt, Christopher J.

Publication type:

Article

A quantitative approach for understanding small-scale human mesenchymal stem cell culture - implications for large-scale bioprocess development.

Published in:

Biotechnology Journal, 2013, v. 8, n. 4, p. 459, doi. 10.1002/biot.201200197

By:

Rafiq, Qasim A.;
Coopman, Karen;
Nienow, Alvin W.;
Hewitt, Christopher J.

Publication type:

Article

Scale-down/scale-up studies leading to improved commercial beer fermentation.

Published in:

Biotechnology Journal, 2011, v. 6, n. 8, p. 911, doi. 10.1002/biot.201000414

By:

Nienow, Alvin W.;
Nordkvist, Mikkel;
Boulton, Christopher A.

Publication type:

Article

Expansion of human mesenchymal stem/stromal cells on temporary liquid microcarriers.

Published in:

Journal of Chemical Technology & Biotechnology, 2021, v. 96, n. 4, p. 930, doi. 10.1002/jctb.6601

By:

Hanga, Mariana P;
Nienow, Alvin W;
Murasiewicz, Halina;
Pacek, Andrzej W;
Hewitt, Christopher J;
Coopman, Karen

Publication type:

Article

Expansion of bone marrow-derived human mesenchymal stem/stromal cells (hMSCs) using a two-phase liquid/liquid system.

Published in:

Journal of Chemical Technology & Biotechnology, 2017, v. 92, n. 7, p. 1577, doi. 10.1002/jctb.5279

By:

Hanga, Mariana P;
Murasiewicz, Halina;
Pacek, Andrzej W;
Nienow, Alvin W;
Coopman, Karen;
Hewitt, Christopher J

Publication type:

Article

Engineering considerations on the use of liquid/liquid two-phase systems as a cell culture platform.

Published in:

Journal of Chemical Technology & Biotechnology, 2017, v. 92, n. 7, p. 1690, doi. 10.1002/jctb.5166

By:

Murasiewicz, Halina;
Nienow, Alvin W;
Hanga, Mariana P;
Coopman, Karen;
Hewitt, Christopher J;
Pacek, Andrzej W

Publication type:

Article

Quantitative Measurements of the Critical Impeller Speed for Solid‐Liquid Suspensions.

Published in:

Chemical Engineering & Technology, 2019, v. 42, n. 8, p. 1643, doi. 10.1002/ceat.201800716

By:

Ye, Guichuan;
Nienow, Alvin W.;
Alberini, Federico

Publication type:

Article

Mixing Studies Related to the Cleaning of Molten Aluminium.

Published in:

Chemical Engineering & Technology, 2004, v. 27, n. 3, p. 310

By:

M. Kimata;
N. Nayan;
W. Bujalski;
Alvin W. Nienow;
J.L. Song;
M.R. Jolly

Publication type:

Article

Forward: ISMIP, 1995 to 2020, THE International Mixing Conference.

Published in:

2018

By:

Nienow, Alvin W.;
Hirata, Yushi

Publication type:

Proceeding

Using positron emission particle tracking (PEPT) to study the turbulent flow in a baffled vessel agitated by a Rushton turbine: Improving data treatment and validation.

Published in:

Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers Part A, 2011, v. 89, n. 10, p. 1947, doi. 10.1016/j.cherd.2011.01.015

By:

Chiti, Fabio;
Bakalis, Serafim;
Bujalski, Waldemar;
Barigou, Mostafa;
Eaglesham, Archie;
Nienow, Alvin W.

Publication type:

Article

Mixing studies in a model aerated bioreactor equipped with an up- or a down-pumping 'Elephant Ear' agitator: Power, hold-up and aerated flow field measurements.

Published in:

Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers Part A, 2009, v. 87, n. 3, p. 307, doi. 10.1016/j.cherd.2008.08.013

By:

Hui Zhu;
Nienow, Alvin W.;
Bujalski, Waldek;
Simnions, Mark J. H.

Publication type:

Article

Mixing by rotary jet heads: Indications of the benefits of head rotation under turbulent and transitional flow conditions.

Published in:

Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers Part A, 2008, v. 86, n. 12, p. 1454, doi. 10.1016/j.cherd.2008.08.010

By:

Nordkvist, Mikkel;
Vognsen, Marie;
Nienow, Alvin W.;
Villadsen, John;
Gernaey, Krist V.

Publication type:

Article

The application of multi-parameter flow cytometry to the study of recombinant Escherichia coli batch fermentation processes.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2004, v. 31, n. 7, p. 311, doi. 10.1007/s10295-004-0151-8

By:

Lewis, Gareth;
Taylor, Ian W.;
Nienow, Alvin W.;
Hewitt, Christopher J.

Publication type:

Article