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VEGF blockade enhances the antitumor effect of BRAF<sup>V</sup><sup>600E</sup> inhibition.
- Published in:
- EMBO Molecular Medicine, 2017, v. 9, n. 2, p. 219, doi. 10.15252/emmm.201505774
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- Publication type:
- Article
Small Nucleolar RNAs Determine Resistance to Doxorubicin in Human Osteosarcoma.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 12, p. 4500, doi. 10.3390/ijms21124500
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- Publication type:
- Article
Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus.
- Published in:
- 2010
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- Publication type:
- journal article
Non-canonical antigens are the largest fraction of peptides presented by MHC class I in mismatch repair deficient murine colorectal cancer.
- Published in:
- Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-023-01275-3
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- Publication type:
- Article
Multi-Determinants Analysis of Molecular Alterations for Predicting Clinical Benefit to EGFR-Targeted Monoclonal Antibodies in Colorectal Cancer.
- Published in:
- PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007287
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- Publication type:
- Article
Evaluation of the Preclinical Efficacy of Lurbinectedin in Malignant Pleural Mesothelioma.
- Published in:
- Cancers, 2021, v. 13, n. 10, p. 2332, doi. 10.3390/cancers13102332
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- Publication type:
- Article
Circulating Methylated DNA to Monitor the Dynamics of RAS Mutation Clearance in Plasma from Metastatic Colorectal Cancer Patients.
- Published in:
- Cancers, 2020, v. 12, n. 12, p. 3633, doi. 10.3390/cancers12123633
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- Publication type:
- Article
Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer.
- Published in:
- Cancers, 2020, v. 12, n. 3, p. 685, doi. 10.3390/cancers12030685
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- Publication type:
- Article
Preclinical efficacy of carfilzomib in BRAF‐mutant colorectal cancer models.
- Published in:
- Molecular Oncology, 2024, v. 18, n. 6, p. 1552, doi. 10.1002/1878-0261.13595
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- Publication type:
- Article
Transcriptome‐wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer.
- Published in:
- Molecular Oncology, 2024, v. 18, n. 6, p. 1460, doi. 10.1002/1878-0261.13622
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- Publication type:
- Article
Dual VEGFA/BRAF targeting boosts PD‐1 blockade in melanoma through GM‐CSF‐mediated infiltration of M1 macrophages.
- Published in:
- Molecular Oncology, 2023, v. 17, n. 8, p. 1474, doi. 10.1002/1878-0261.13450
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- Publication type:
- Article
Exploiting DNA repair defects in colorectal cancer.
- Published in:
- Molecular Oncology, 2019, v. 13, n. 4, p. 681, doi. 10.1002/1878-0261.12467
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- Publication type:
- Article
Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAF V600E Protein.
- Published in:
- Molecules, 2022, v. 27, n. 23, p. 8513, doi. 10.3390/molecules27238513
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- Publication type:
- Article
Prediction of homologous recombination deficiency identifies colorectal tumors sensitive to PARP inhibition.
- Published in:
- NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00706-7
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- Publication type:
- Article
Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model.
- Published in:
- FASEB Journal, 2015, v. 29, n. 2, p. 464, doi. 10.1096/fj.14-262303
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- Publication type:
- Article
Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Mutational signatures of colorectal cancers according to distinct computational workflows.
- Published in:
- Briefings in Bioinformatics, 2024, v. 25, n. 4, p. 1, doi. 10.1093/bib/bbae249
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- Publication type:
- Article
Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer.
- Published in:
- Nature Communications, 2016, v. 7, n. 12, p. 13665, doi. 10.1038/ncomms13665
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- Publication type:
- Article
Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers.
- Published in:
- Nature Communications, 2015, v. 6, n. 9, p. 8305, doi. 10.1038/ncomms9305
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- Publication type:
- Article
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
- Published in:
- Nature Communications, 2015, v. 6, n. 4, p. 7002, doi. 10.1038/ncomms8002
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- Publication type:
- Article
High-dose vitamin C enhances cancer immunotherapy.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 532, p. 1, doi. 10.1126/scitranslmed.aay8707
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- Publication type:
- Article
MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations.
- Published in:
- Science Translational Medicine, 2016, v. 8, n. 324, p. 1, doi. 10.1126/scitranslmed.aad5640
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- Publication type:
- Article
A Genomic Analysis Workflow for Colorectal Cancer Precision Oncology.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Parallel Evaluation of Circulating Tumor DNA and Circulating Tumor Cells in Metastatic Colorectal Cancer.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer.
- Published in:
- Science Translational Medicine, 2014, v. 6, n. 224, p. 1, doi. 10.1126/scitranslmed.3007947
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- Publication type:
- Article
RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer.
- Published in:
- Cell Death & Disease, 2020, v. 11, n. 10, p. 1, doi. 10.1038/s41419-020-03131-3
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- Publication type:
- Article
Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.
- Published in:
- Nature, 2012, v. 483, n. 7387, p. 100, doi. 10.1038/nature10868
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- Publication type:
- Article
The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination.
- Published in:
- Scientific Reports, 2015, p. 9054, doi. 10.1038/srep09054
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- Publication type:
- Article
Reliance upon ancestral mutations is maintained in colorectal cancers that heterogeneously evolve during targeted therapies.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04506-z
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- Publication type:
- Article
The impact of T cell mediated immune surveillance on epithelial cancer cells with mismatch repair alterations.
- Published in:
- 2018
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- Publication type:
- Abstract
Exploring circular MET RNA as a potential biomarker in tumors exhibiting high MET activity.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2023, v. 42, n. 1, p. 1, doi. 10.1186/s13046-023-02690-5
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- Publication type:
- Article
Exploring circular MET RNA as a potential biomarker in tumors exhibiting high MET activity.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2023, v. 42, n. 1, p. 1, doi. 10.1186/s13046-023-02690-5
- By:
- Publication type:
- Article
Integrated molecular dissection of the epidermal growth factor receptor (EGFR) [corrected] oncogenic pathway to predict response to EGFR-targeted monoclonal antibodies in metastatic colorectal cancer.
- Published in:
- 2010
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- Publication type:
- journal article
Targeted Knock-in of the Polymorphism rs61764370 Does Not Affect KRAS Expression but Reduces let-7 Levels.
- Published in:
- Human Mutation, 2014, v. 35, n. 2, p. 208, doi. 10.1002/humu.22487
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- Publication type:
- Article
Modeling Tumor Progression by the Sequential Introduction of Genetic Alterations into the Genome of Human Normal Cells.
- Published in:
- Human Mutation, 2013, v. 34, n. 2, p. 330, doi. 10.1002/humu.22234
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- Publication type:
- Article
Genomic landscape and survival analysis of ctDNA "neo-RAS wild-type" patients with originally RAS mutant metastatic colorectal cancer.
- Published in:
- Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1160673
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- Publication type:
- Article
Association of KRAS p.G13D Mutation With Outcome in Patients With Chemotherapy- Refractory Metastatic Colorectal Cancer Treated With Cetuximab.
- Published in:
- JAMA: Journal of the American Medical Association, 2010, v. 304, n. 16, p. 1812, doi. 10.1001/jama.2010.1535
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- Publication type:
- Article
The neuronal protein Neuroligin 1 promotes colorectal cancer progression by modulating the APC/β-catenin pathway.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-022-02465-4
- By:
- Publication type:
- Article
ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer.
- Published in:
- 2009
- By:
- Publication type:
- journal article
Biomarkers Predicting Clinical Outcome of Epidermal Growth Factor Receptor–Targeted Therapy in Metastatic Colorectal Cancer.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2009, v. 101, n. 19, p. 1308, doi. 10.1093/jnci/djp280
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- Publication type:
- Article
Evolving neoantigen profiles in colorectal cancers with DNA repair defects.
- Published in:
- Genome Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13073-019-0654-6
- By:
- Publication type:
- Article
Acquired resistance to EGFR-targeted therapies in colorectal cancer.
- Published in:
- Molecular Oncology, 2014, v. 8, n. 6, p. 1084, doi. 10.1016/j.molonc.2014.05.003
- By:
- Publication type:
- Article
Prognostic significance of cyclooxygenase-2 (COX-2) expression patients with surgically resectable adenocarcinoma of oesophagus.
- Published in:
- BMC Cancer, 2006, v. 6, p. 134, doi. 10.1186/1471-2407-6-134
- By:
- Publication type:
- Article
Cancer cell adaptation to chemotherapy.
- Published in:
- BMC Cancer, 2005, v. 5, p. 78, doi. 10.1186/1471-2407-5-78
- By:
- Publication type:
- Article
Outcome of ATP-based tumor chemosensitivity assay directed chemotherapy in heavily pre-treated recurrent ovarian carcinoma.
- Published in:
- BMC Cancer, 2003, v. 3, p. 19, doi. 10.1186/1471-2407-3-19
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- Publication type:
- Article