Works by Nicola A. Colabufo
Results: 64
Towards metabolically stable 5-HT receptor ligands: a study on 1-arylpiperazine derivatives and related isosters.
- Published in:
- Experimental Brain Research, 2013, v. 230, n. 4, p. 569, doi. 10.1007/s00221-013-3498-0
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- Article
6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 974, doi. 10.1080/14756366.2020.1747449
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- Article
Editorial: The CB2 Cannabinoid System: A New Strategy in Neurodegenerative Disorder and Neuroinflammation.
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- 2017
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- Editorial
Functionalized Coumarine Fragment to Obtain Fluorescent and Selective P-Glycoprotein Ligands.
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- Archiv der Pharmazie, 2016, v. 349, n. 3, p. 161, doi. 10.1002/ardp.201500325
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- Article
2-Deoxyglycosylation towards more effective and bioavailable neuroprotective molecules inspired by nature.
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- Pure & Applied Chemistry, 2019, v. 91, n. 7, p. 1209, doi. 10.1515/pac-2019-0303
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- Article
Vascular Toxicity Risk Assessment of MC18 and MC70, Novel Potential Diagnostic Tools for In Vivo PET Studies.
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- Basic & Clinical Pharmacology & Toxicology, 2017, v. 120, n. 5, p. 434, doi. 10.1111/bcpt.12719
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- Article
Head-to-head comparison of (R)-[<sup>11</sup>C]verapamil and [<sup>18</sup>F]MC225 in non-human primates, tracers for measuring P-glycoprotein function.
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- European Journal of Nuclear Medicine & Molecular Imaging, 2021, v. 48, n. 13, p. 4307, doi. 10.1007/s00259-021-05411-2
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- Article
Evaluation of P-glycoprotein function at the blood–brain barrier using [<sup>18</sup>F]MC225-PET.
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- European Journal of Nuclear Medicine & Molecular Imaging, 2021, v. 48, n. 12, p. 4105, doi. 10.1007/s00259-021-05419-8
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- Article
Synthesis and binding profile of constrained analogues of N-[4-(4-arylpiperazin-1-yl)butyl]-3-methoxybenzamides, a class of potent dopamine D3 receptor ligands.
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- Journal of Pharmacy & Pharmacology, 2006, v. 58, n. 2, p. 209
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- Article
Distribution of sigma receptors in EMT-6 cells: preliminary biological evaluation of PB167 and potential for in-vivo PET.
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- Journal of Pharmacy & Pharmacology, 2005, v. 57, n. 11, p. 1453
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- Article
Design and synthesis of long-chain arylpiperazines with mixed affinity for serotonin transporter (SERT) and 5-HT1A receptor.
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- Journal of Pharmacy & Pharmacology, 2005, v. 57, n. 10, p. 1319
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- Publication type:
- Article
Studies on 1-arylpiperazine derivatives with affinity for rat 5-HT<sub>7</sub> and 5-HT<sub>1A</sub> receptors.
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- Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 2, p. 247
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- Publication type:
- Article
A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39662-w
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- Article
ABC transporters in CSCs membranes as a novel target for treating tumor relapse.
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- Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00163
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- Article
Herbal Medicines in Brazil: Pharmacokinetic Profile and Potential Herb-Drug Interactions.
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- Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00162
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- Article
ABC transporters in CSCs membranes as a novel target for treating tumour relapse.
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- Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00163
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- Article
Antiproliferative and cytotoxic effects of some σ<sub>2</sub> agonists and σ<sub>1</sub> antagonists in tumour cell lines.
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- Naunyn-Schmiedeberg's Archives of Pharmacology, 2004, v. 370, n. 2, p. 106
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- Article
A new method for evaluating σ<sub>2</sub> ligand activity in the isolated guinea-pig bladder.
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- Naunyn-Schmiedeberg's Archives of Pharmacology, 2003, v. 368, n. 2, p. 106, doi. 10.1007/s00210-003-0777-5
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- Publication type:
- Article
Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine.
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- Pharmacology Research & Perspectives, 2015, v. 3, n. 5, p. 1, doi. 10.1002/prp2.160
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- Article
Evaluations about the physico-chemical stability of docetaxel and irinotecan pre-diluted and diluted solutions: pharmaco-economic perspectives.
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- Drugs & Therapy Studies, 2013, v. 3, n. 1, p. 24, doi. 10.4081/dts.2013.e6
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- Article
Guinea-pig ileum as ex vivo model useful to characterize ligands displaying Imidazoline I<sub>2</sub> and Adrenergic alpha<sub>2</sub> mixed activity: a preliminary study.
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- Drugs & Therapy Studies, 2013, v. 3, n. 1, p. 1, doi. 10.4081/dts.2013.e1
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- Publication type:
- Article
Design, Synthesis, Lipophilic Properties, and Binding Affinities of Potential Ligands in Positron Emission Tomography (PET) for Visualization of Brain Dopamine D<sub>4</sub> Receptors.
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- Chemistry & Biodiversity, 2014, v. 11, n. 2, p. 299, doi. 10.1002/cbdv.201300194
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- Article
Selective agonists for serotonin 7 (5-HT<sub>7</sub>) receptor and their applications in preclinical models: an overview.
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- Reviews in the Neurosciences, 2014, v. 25, n. 3, p. 401, doi. 10.1515/revneuro-2014-0009
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- Publication type:
- Article
First clinical assessment of [<sup>18</sup>F]MC225, a novel fluorine-18 labelled PET tracer for measuring functional P-glycoprotein at the blood–brain barrier.
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- Annals of Nuclear Medicine, 2021, v. 35, n. 11, p. 1240, doi. 10.1007/s12149-021-01666-9
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- Article
Tc(N)-DBODC(5), a potential radiolabeled probe for SPECT of multidrug resistance: in vitro study.
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- Journal of Biological Inorganic Chemistry (JBIC), 2013, v. 18, n. 5, p. 523, doi. 10.1007/s00775-013-0997-1
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- Article
Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06488-4
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- Article
Assessing the Optimal Deoxygenation Pattern of Dodecyl Glycosides for Antimicrobial Activity Against Bacillus anthracis.
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- European Journal of Organic Chemistry, 2019, v. 2019, n. 12, p. 2224, doi. 10.1002/ejoc.201801764
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- Publication type:
- Article
Design, synthesis, biological evaluation, NMR and DFT studies of structurally simplified trimethoxy benzamides as selective P-glycoprotein inhibitors: the role of molecular flatness.
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- Chemical Biology & Drug Design, 2016, v. 88, n. 6, p. 820, doi. 10.1111/cbdd.12811
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- Article
Non-Ceruloplasmin Copper Distincts Subtypes in Alzheimer's Disease: a Genetic Study of ATP7B Frequency.
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- Molecular Neurobiology, 2017, v. 54, n. 1, p. 671, doi. 10.1007/s12035-015-9664-6
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- Article
Erratum to: Non-Ceruloplasmin Copper Distincts Subtypes in Alzheimer's Disease: a Genetic Study of ATP7B Frequency.
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- 2017
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- Erratum
PB28, the Sigma-1 and Sigma-2 Receptors Modulator With Potent Anti–SARS-CoV-2 Activity: A Review About Its Pharmacological Properties and Structure Affinity Relationships.
- Published in:
- Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.589810
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- Publication type:
- Article
Automated synthesis, preclinical toxicity, and radiation dosimetry of [18F]MC225 for clinical use: a tracer for measuring P-glycoprotein function at the blood-brain barrier.
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- EJNMMI Research, 2020, v. 10, n. 1, p. 1, doi. 10.1186/s13550-020-00674-6
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- Article
Overcoming Multidrug Resistance (MDR): Design, Biological Evaluation and Molecular Modelling Studies of 2,4‐Substituted Quinazoline Derivatives.
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- ChemMedChem, 2022, v. 17, n. 12, p. 1, doi. 10.1002/cmdc.202200027
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- Article
Corrigendum: Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use‐Dependent Inhibitors of Voltage‐Gated Sodium Channels.
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- ChemMedChem, 2022, v. 17, n. 7, p. 1, doi. 10.1002/cmdc.202200131
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- Article
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use‐Dependent Inhibitors of Voltage‐Gated Sodium Channels.
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- ChemMedChem, 2021, v. 16, n. 23, p. 3588, doi. 10.1002/cmdc.202100496
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- Article
A New Class of 1‐Aryl‐5,6‐dihydropyrrolo[2,1‐a]isoquinoline Derivatives as Reversers of P‐Glycoprotein‐Mediated Multidrug Resistance in Tumor Cells.
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- ChemMedChem, 2018, v. 13, n. 15, p. 1588, doi. 10.1002/cmdc.201800177
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- Article
Structure-Activity Relationship Studies on 6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline Derivatives as Multidrug Resistance Reversers.
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- ChemMedChem, 2017, v. 12, n. 16, p. 1369, doi. 10.1002/cmdc.201700239
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- Article
A Potent and Selective P-gp Modulator for Altering Multidrug Resistance Due to Pump Overexpression.
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- ChemMedChem, 2016, v. 11, n. 4, p. 374, doi. 10.1002/cmdc.201500538
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- Publication type:
- Article
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules.
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- ChemMedChem, 2016, v. 11, n. 1, p. 93, doi. 10.1002/cmdc.201500417
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- Publication type:
- Article
<sup>11</sup>C- and <sup>18</sup>F-Labeled Radioligands for P-Glycoprotein Imaging by Positron Emission Tomography.
- Published in:
- ChemMedChem, 2016, v. 11, n. 1, p. 108, doi. 10.1002/cmdc.201500420
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- Publication type:
- Article
Arylamino Esters As P-Glycoprotein Modulators: SAR Studies to Establish Requirements for Potency and Selectivity.
- Published in:
- ChemMedChem, 2015, v. 10, n. 8, p. 1339, doi. 10.1002/cmdc.201500143
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- Article
PET Radiotracers for Imaging P-glycoprotein: The Challenge for Early Diagnosis in AD.
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- ChemMedChem, 2014, v. 9, n. 1, p. 38, doi. 10.1002/cmdc.201300362
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- Article
Inside Cover: Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity (ChemMedChem 12/2013).
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- ChemMedChem, 2013, v. 8, n. 12, p. 1898, doi. 10.1002/cmdc.201390051
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- Publication type:
- Article
Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity.
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- ChemMedChem, 2013, v. 8, n. 12, p. 2026, doi. 10.1002/cmdc.201300291
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- Publication type:
- Article
A Benzopyrane Derivative as a P-Glycoprotein Stimulator: A Potential Agent to Decrease β-Amyloid Accumulation in Alzheimer's Disease.
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- ChemMedChem, 2012, v. 7, n. 3, p. 391, doi. 10.1002/cmdc.201100469
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- Article
Inside Cover: 1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ<sub>8</sub>-Δ<sub>7</sub> Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity (ChemMedChem 1/2011).
- Published in:
- ChemMedChem, 2011, v. 6, n. 1, p. 2, doi. 10.1002/cmdc.201090062
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- Publication type:
- Article
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ<sub>8</sub>-Δ<sub>7</sub> Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity.
- Published in:
- ChemMedChem, 2011, v. 6, n. 1, p. 73, doi. 10.1002/cmdc.201000371
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- Article
Chiral Aryloxyalkylamines: Selective 5-HT<sub>1B/1D</sub> Activation and Analgesic Activity.
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- ChemMedChem, 2010, v. 5, n. 5, p. 696, doi. 10.1002/cmdc.200900530
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- Publication type:
- Article
Multi-Drug-Resistance-Reverting Agents: 2-Aryloxazole and 2-Arylthiazole Derivatives as Potent BCRP or MRP1 Inhibitors.
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- ChemMedChem, 2009, v. 4, n. 2, p. 188, doi. 10.1002/cmdc.200800329
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- Article
Gut-Derived Uremic Toxins in CKD: An Improved Approach for the Evaluation of Serum Indoxyl Sulfate in Clinical Practice.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5142, doi. 10.3390/ijms24065142
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- Publication type:
- Article