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Muscarinic receptor drug trihexyphenidyl can alter growth of mesenchymal glioblastoma in vivo.
Published in:
Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1468920
By:
- Du, Renfei;
- Sanin, Ahmed Y.;
- Shi, Wenjie;
- Huang, Bing;
- Nickel, Ann-Christin;
- Vargas-Toscano, Andres;
- Huo, Shuran;
- Nickl-Jockschat, Thomas;
- Dumitru, Claudia A.;
- Hu, Wei;
- Duan, Siyu;
- Sandalcioglu, I. Erol;
- Croner, Roland S.;
- Alcaniz, Joshua;
- Walther, Wolfgang;
- Berndt, Carsten;
- Kahlert, Ulf D.
Publication type:
Article
Augmented Therapeutic Potential of Glutaminase Inhibitor CB839 in Glioblastoma Stem Cells Using Gold Nanoparticle Delivery.
Published in:
Pharmaceutics, 2021, v. 13, n. 2, p. 295, doi. 10.3390/pharmaceutics13020295
By:
- Giesen, Beatriz;
- Nickel, Ann-Christin;
- Barthel, Juri;
- Kahlert, Ulf Dietrich;
- Janiak, Christoph;
- Pricl, Sabrina
Publication type:
Article
Testing the Stability of Drug Resistance on Cryopreserved, Gene-Engineered Human Induced Pluripotent Stem Cells.
Published in:
Pharmaceuticals (14248247), 2021, v. 14, n. 9, p. 919, doi. 10.3390/ph14090919
By:
- Khan, Dilaware;
- Nickel, Ann-Christin;
- Jeising, Sebastian;
- Uhlmann, Constanze;
- Muhammad, Sajjad;
- Hänggi, Daniel;
- Fischer, Igor;
- Kahlert, Ulf Dietrich
Publication type:
Article
CD133-Functionalized Gold Nanoparticles as a Carrier Platform for Telaglenastat (CB-839) against Tumor Stem Cells.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 10, p. 5479, doi. 10.3390/ijms23105479
By:
- Poonaki, Elham;
- Nickel, Ann-Christin;
- Shafiee Ardestani, Mehdi;
- Rademacher, Lars;
- Kaul, Marilyn;
- Apartsin, Evgeny;
- Meuth, Sven G.;
- Gorji, Ali;
- Janiak, Christoph;
- Kahlert, Ulf Dietrich
Publication type:
Article
The development of a hiPSC-based platform to identify tissue-dependencies of IDH1 R132H.
Published in:
Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01747-w
By:
- Mehjardi, N. Z.;
- Kessler, J.;
- Sanin, A. Y.;
- Picard, D.;
- Westhoff, P.;
- Nickel, Ann-Christin;
- Uhlmann, C.;
- Shi, W.;
- Steiger, H. J.;
- Remke, M.;
- Fischer, I.;
- Vordermark, D.;
- Croner, R. S.;
- Kahlert, U. D.
Publication type:
Article
WNT/β-Catenin-Mediated Resistance to Glucose Deprivation in Glioblastoma Stem-like Cells.
Published in:
Cancers, 2022, v. 14, n. 13, p. N.PAG, doi. 10.3390/cancers14133165
By:
- Yusuf, Suad;
- Aretz, Philippe;
- Nickel, Ann-Christin;
- Westhoff, Philipp;
- Sharma, Amit;
- Qin, Nan;
- Remke, Marc;
- Steiger, Hans-Jakob;
- Hänggi, Daniel;
- Liu, Hongjia;
- Liu, Hongde;
- Neumann, Silke;
- Reifenberger, Guido;
- Maciaczyk, Jarek
Publication type:
Article
Current Technologies for RNA-Directed Liquid Diagnostics.
Published in:
Cancers, 2021, v. 13, n. 20, p. 5060, doi. 10.3390/cancers13205060
By:
- Martinez-Dominguez, Maria Victoria;
- Zottel, Alja;
- Šamec, Neja;
- Jovčevska, Ivana;
- Dincer, Can;
- Kahlert, Ulf Dietrich;
- Nickel, Ann-Christin
Publication type:
Article
Rapalink-1 Targets Glioblastoma Stem Cells and Acts Synergistically with Tumor Treating Fields to Reduce Resistance against Temozolomide.
Published in:
Cancers, 2020, v. 12, n. 12, p. 3859, doi. 10.3390/cancers12123859
By:
- Vargas-Toscano, Andres;
- Nickel, Ann-Christin;
- Li, Guanzhang;
- Kamp, Marcel Alexander;
- Muhammad, Sajjad;
- Leprivier, Gabriel;
- Fritsche, Ellen;
- Barker, Roger A.;
- Sabel, Michael;
- Steiger, Hans-Jakob;
- Zhang, Wei;
- Hänggi, Daniel;
- Kahlert, Ulf Dietrich
Publication type:
Article
A computational guided, functional validation of a novel therapeutic antibody proposes Notch signaling as a clinical relevant and druggable target in glioma.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72480-y
By:
- Herrera-Rios, Dayana;
- Li, Guanzhang;
- Khan, Dilaware;
- Tsiampali, Julia;
- Nickel, Ann-Christin;
- Aretz, Philippe;
- Hewera, Michael;
- Suwala, Abiagail Kora;
- Jiang, Tao;
- Steiger, Hans-Jakob;
- Kamp, Marcel Alexander;
- Muhammad, Sajjad;
- Hänggi, Daniel;
- Maciaczyk, Jarek;
- Zhang, Wei;
- Kahlert, Ulf Dietrich
Publication type:
Article
A comparative pharmaco-metabolomic study of glutaminase inhibitors in glioma stem-like cells confirms biological effectiveness but reveals differences in target-specificity.
Published in:
Cell Death Discovery, 2020, v. 6, n. 1, p. 1, doi. 10.1038/s41420-020-0258-3
By:
- Koch, Katharina;
- Hartmann, Rudolf;
- Tsiampali, Julia;
- Uhlmann, Constanze;
- Nickel, Ann-Christin;
- He, Xiaoling;
- Kamp, Marcel A.;
- Sabel, Michael;
- Barker, Roger A.;
- Steiger, Hans-Jakob;
- Hänggi, Daniel;
- Willbold, Dieter;
- Maciaczyk, Jaroslaw;
- Kahlert, Ulf D.
Publication type:
Article
Different Calculation Strategies Are Congruent in Determining Chemotherapy Resistance of Brain Tumors In Vitro.
Published in:
Cells (2073-4409), 2020, v. 9, n. 12, p. 2689, doi. 10.3390/cells9122689
By:
- Fischer, Igor;
- Nickel, Ann-Christin;
- Qin, Nan;
- Taban, Kübra;
- Pauck, David;
- Steiger, Hans-Jakob;
- Kamp, Marcel;
- Muhammad, Sajjad;
- Hänggi, Daniel;
- Fritsche, Ellen;
- Remke, Marc;
- Kahlert, Ulf Dietrich
Publication type:
Article
A clinically compatible in vitro drug-screening platform identifies therapeutic vulnerabilities in primary cultures of brain metastases.
Published in:
Journal of Neuro-Oncology, 2024, v. 169, n. 3, p. 613, doi. 10.1007/s11060-024-04763-7
By:
- Jeising, Sebastian;
- Nickel, Ann-Christin;
- Trübel, Johanna;
- Felsberg, Jörg;
- Picard, Daniel;
- Leprivier, Gabriel;
- Wolter, Marietta;
- Huynh, My Ky;
- Olivera, Marlene B.;
- Kaulich, Kerstin;
- Häberle, Lena;
- Esposito, Irene;
- Klau, Gunnar W.;
- Steinmann, Julia;
- Beez, Thomas;
- Rapp, Marion;
- Sabel, Michael;
- Dietrich, Sascha;
- Remke, Marc;
- Cornelius, Jan F.
Publication type:
Article
A clinically compatible in vitro drug-screening platform identifies therapeutic vulnerabilities in primary cultures of brain metastases.
Published in:
Journal of Neuro-Oncology, 2024, v. 169, n. 2, p. 613, doi. 10.1007/s11060-024-04763-7
By:
- Jeising, Sebastian;
- Nickel, Ann-Christin;
- Trübel, Johanna;
- Felsberg, Jörg;
- Picard, Daniel;
- Leprivier, Gabriel;
- Wolter, Marietta;
- Huynh, My Ky;
- Olivera, Marlene B.;
- Kaulich, Kerstin;
- Häberle, Lena;
- Esposito, Irene;
- Klau, Gunnar W.;
- Steinmann, Julia;
- Beez, Thomas;
- Rapp, Marion;
- Sabel, Michael;
- Dietrich, Sascha;
- Remke, Marc;
- Cornelius, Jan F.
Publication type:
Article
Loss of programmed cell death 10 activates tumor cells and leads to temozolomide-resistance in glioblastoma.
Published in:
Journal of Neuro-Oncology, 2019, v. 141, n. 1, p. 31, doi. 10.1007/s11060-018-03017-7
By:
- Nickel, Ann-Christin;
- Wan, Xue-Yan;
- Saban, Dino-Vitali;
- Weng, Yin-Lun;
- Zhang, Shu;
- Keyvani, Kathy;
- Sure, Ulrich;
- Zhu, Yuan
Publication type:
Article
Progenitor cells derived from gene‐engineered human induced pluripotent stem cells as synthetic cancer cell alternatives for in vitro pharmacology.
Published in:
Biotechnology Journal, 2022, v. 17, n. 6, p. 1, doi. 10.1002/biot.202100693
By:
- Uhlmann, Constanze;
- Nickel, Ann‐Christin;
- Picard, Daniel;
- Rossi, Andrea;
- Li, Guanzhang;
- Hildebrandt, Barbara;
- Brockerhoff, Gabriele;
- Bendt, Farina;
- Hübenthal, Ulrike;
- Hewera, Michael;
- Steiger, Hans‐Jakob;
- Wieczorek, Dagmar;
- Perrakis, Aristoteles;
- Zhang, Wei;
- Remke, Marc;
- Koch, Katharina;
- Tigges, Julia;
- Croner, Roland S.;
- Fritsche, Ellen;
- Kahlert, Ulf D.
Publication type:
Article
Nerve growth factor regulates the expression of the cholinergic locus and the high-affinity choline transporter via the Akt/PKB signaling pathway.
Published in:
Journal of Neurochemistry, 2008, v. 107, n. 5, p. 1284, doi. 10.1111/j.1471-4159.2008.05681.x
By:
- Madziar, Beata;
- Shah, Sonia;
- Brock, Martina;
- Burke, Rebecca;
- Lopez-Coviella, Ignacio;
- Nickel, Ann-Christin;
- Cakal, Esra Betul;
- Blusztajn, Jan Krzysztof;
- Berse, Brygida
Publication type:
Article
Muscarinic receptor drug trihexyphenidyl can alter growth of mesenchymal glioblastoma in vivo.
Published in:
Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1468920
By:
- Renfei Du;
- Sanin, Ahmed Y.;
- Wenjie Shi;
- Bing Huang;
- Nickel, Ann-Christin;
- Vargas-Toscano, Andres;
- Shuran Huo;
- Nickl-Jockschat, Thomas;
- Dumitru, Claudia A.;
- Wei Hu;
- Siyu Duan;
- Sandalcioglu, I. Erol;
- Croner, Roland S.;
- Alcaniz, Joshua;
- Walther, Wolfgang;
- Berndt, Carsten;
- Kahlert, Ulf D.
Publication type:
Article
Muscarinic receptor drug trihexyphenidyl can alter growth of mesenchymal glioblastoma in vivo.
Published in:
Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1468920
By:
- Renfei Du;
- Sanin, Ahmed Y.;
- Wenjie Shi;
- Bing Huang;
- Nickel, Ann-Christin;
- Vargas-Toscano, Andres;
- Shuran Huo;
- Nickl-Jockschat, Thomas;
- Dumitru, Claudia A.;
- Wei Hu;
- Siyu Duan;
- Sandalcioglu, I. Erol;
- Croner, Roland S.;
- Alcaniz, Joshua;
- Walther, Wolfgang;
- Berndt, Carsten;
- Kahlert, Ulf D.
Publication type:
Article
Carbonic Anhydrase XII is a Clinically Significant, Molecular Tumor-Subtype Specific Therapeutic Target in Glioma with the Potential to Combat Invasion of Brain Tumor Cells.
Published in:
OncoTargets & Therapy, 2021, v. 14, p. 1707, doi. 10.2147/OTT.S300623
By:
- Li, Guanzhang;
- Chen, Ting-Wei;
- Nickel, Ann-Christin;
- Muhammad, Sajjad;
- Steiger, Hans-Jakob;
- Tzaridis, Theophilos;
- Hänggi, Daniel;
- Zeidler, Reinhard;
- Zhang, Wei;
- Kahlert, Ulf Dietrich
Publication type:
Article

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