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Lack of endogenous tau permits tau spreading and protects against tau toxicity in transgenic mice.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P186, doi. 10.1016/j.jalz.2015.07.159
By:
- Wegmann, Susanne;
- Maury, Eduardo A.;
- Kirk, Molly J.;
- Saqran, Lubna;
- Roe, Allyson D.;
- Fan, Zhanyun;
- Nicholls, Samantha B.;
- DeVos, Sarah L.;
- Takeda, Shuko;
- William, Christopher M.;
- Spires-Jones, Tara L.;
- Pitstick, Rose;
- Carlson, George A.;
- Pooler, Amy;
- Hyman, Bradley T.
Publication type:
Article
Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease.
Published in:
Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0199-x
By:
- Pooler, Amy M.;
- Polydoro, Manuela;
- Maury, Eduardo A.;
- Nicholls, Samantha B.;
- Reddy, Snigdha M.;
- Wegmann, Susanne;
- William, Christopher;
- Saqran, Lubna;
- Cagsal-Getkin, Ozge;
- Pitstick, Rose;
- Beier, David R.;
- Carlson, George A.;
- Spires-Jones, Tara L.;
- Hyman, Bradley T.
Publication type:
Article
Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease.
Published in:
Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0199-x
By:
- Pooler, Amy M.;
- Polydoro, Manuela;
- Maury, Eduardo A.;
- Nicholls, Samantha B.;
- Reddy, Snigdha M.;
- Wegmann, Susanne;
- William, Christopher;
- Saqran, Lubna;
- Cagsal-Getkin, Ozge;
- Pitstick, Rose;
- Beier, David R.;
- Carlson, George A.;
- Spires-Jones, Tara L.;
- Hyman, Bradley T.
Publication type:
Article
Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain.
Published in:
Scientific Reports, 2015, p. 8490, doi. 10.1038/ncomms9490
By:
- Takeda, Shuko;
- Wegmann, Susanne;
- Cho, Hansang;
- DeVos, Sarah L.;
- Commins, Caitlin;
- Roe, Allyson D.;
- Nicholls, Samantha B.;
- Carlson, George A.;
- Pitstick, Rose;
- Nobuhara, Chloe K.;
- Costantino, Isabel;
- Frosch, Matthew P.;
- Müller, Daniel J.;
- Irimia, Daniel;
- Hyman, Bradley T.
Publication type:
Article
Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain.
Published in:
Nature Communications, 2015, v. 6, n. 10, p. 8490, doi. 10.1038/ncomms9490
By:
- Takeda, Shuko;
- Wegmann, Susanne;
- Cho, Hansang;
- DeVos, Sarah L.;
- Commins, Caitlin;
- Roe, Allyson D.;
- Nicholls, Samantha B.;
- Carlson, George A.;
- Pitstick, Rose;
- Nobuhara, Chloe K.;
- Costantino, Isabel;
- Frosch, Matthew P.;
- Müller, Daniel J.;
- Irimia, Daniel;
- Hyman, Bradley T.
Publication type:
Article
Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients.
Published in:
2016
By:
- Takeda, Shuko;
- Commins, Caitlin;
- DeVos, Sarah L.;
- Nobuhara, Chloe K.;
- Wegmann, Susanne;
- Roe, Allyson D.;
- Costantino, Isabel;
- Fan, Zhanyun;
- Nicholls, Samantha B.;
- Sherman, Alexis E.;
- Trisini Lipsanopoulos, Ana T.;
- Scherzer, Clemens R.;
- Carlson, George A.;
- Pitstick, Rose;
- Peskind, Elaine R.;
- Raskind, Murray A.;
- Li, Ge;
- Montine, Thomas J.;
- Frosch, Matthew P.;
- Hyman, Bradley T.
Publication type:
journal article
Risk-Based Control Strategies of Recombinant Monoclonal Antibody Charge Variants.
Published in:
Antibodies (2073-4468), 2022, v. 11, n. 4, p. 73, doi. 10.3390/antib11040073
By:
- Beck, Alain;
- Nowak, Christine;
- Meshulam, Deborah;
- Reynolds, Kristina;
- Chen, David;
- Pacardo, Dennis B.;
- Nicholls, Samantha B.;
- Carven, Gregory J.;
- Gu, Zhenyu;
- Fang, Jing;
- Wang, Dongdong;
- Katiyar, Amit;
- Xiang, Tao;
- Liu, Hongcheng
Publication type:
Article
Structural basis of fluorescence quenching in caspase activatable-GFP.
Published in:
Protein Science: A Publication of the Protein Society, 2013, v. 22, n. 3, p. 247, doi. 10.1002/pro.2188
By:
- Nicholls, Samantha B.;
- Hardy, Jeanne A.
Publication type:
Article
Characterization of TauC3 antibody and demonstration of its potential to block tau propagation.
Published in:
PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0177914
By:
- Nicholls, Samantha B.;
- DeVos, Sarah L.;
- Commins, Caitlin;
- Nobuhara, Chloe;
- Bennett, Rachel E.;
- Corjuc, Diana L.;
- Maury, Eduardo;
- Eftekharzadeh, Bahareh;
- Akingbade, Ololade;
- Fan, Zhanyun;
- Roe, Allyson D.;
- Takeda, Shuko;
- Wegmann, Susanne;
- Hyman, Bradley T.
Publication type:
Article
Reversal of Neurofibrillary Tangles and Tau-Associated Phenotype in the rTgTauEC Model of Early Alzheimer's Disease.
Published in:
Journal of Neuroscience, 2013, v. 33, n. 33, p. 13300, doi. 10.1523/JNEUROSCI.0881-13.2013
By:
- Polydoro, Manuela;
- de Calignon, Alix;
- Suárez-Calvet, Marc;
- Sanchez, Laura;
- Kay, Kevin R.;
- Nicholls, Samantha B.;
- Roe, Allyson D.;
- Pitstick, Rose;
- Carlson, George A.;
- Gómez-Isla, Teresa;
- Spires-Jones, Tara L.;
- Hyman, Bradley T.
Publication type:
Article

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