Works by Nicholas J. Schork

Results: 170

Association of direct-to-consumer genome-wide disease risk estimates and self-reported disease.

Published in:

Genetic Epidemiology, 2012, v. 36, n. 1, p. 66, doi. 10.1002/gepi.20664

By:

Bloss, Cinnamon S.;
Topol, Eric J.;
Schork, Nicholas J.

Publication type:

Article

Powerful designs for genetic association studies that consider twins and sibling pairs with discordant genotypes.

Published in:

Genetic Epidemiology, 2007, v. 31, n. 7, p. 789, doi. 10.1002/gepi.20241

By:

Wessel, Jennifer;
Schork, Andrew J.;
Tiwari, Hemant K.;
Schork, Nicholas J.

Publication type:

Article

Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the Family Blood Pressure Program.

Published in:

Genetic Epidemiology, 2007, v. 31, n. 3, p. 195, doi. 10.1002/gepi.20202

By:

Greenwood, Tiffany A.;
Libiger, Ondrej;
Kardia, Sharon;
Hanis, Craig;
Morrison, Alanna C.;
Gu, C. Charles;
Rice, Treva;
Miller, Michael;
Turner, Stephen T.;
Myers, Richard H.;
Grove, John;
Hsiao, Chin-Fu;
Weder, Alan B.;
Schork, Nicholas J.

Publication type:

Article

Two-Trait-Locus Linkage Analyses of Asthma Susceptibility.

Published in:

Genetic Epidemiology, 2001, v. 21, p. S278, doi. 10.1002/gepi.2001.21.s1.s278

By:

Nath, Swapan K.;
Chen, Chien-Hsiun;
Schork, Nicholas J.

Publication type:

Article

Detection of genetic heterogeneity for complex quantitative phenotypes.

Published in:

Genetic Epidemiology, 1992, v. 9, n. 3, p. 207, doi. 10.1002/gepi.1370090307

By:

Schork, Nicholas J.;
Chakravarti, Aravinda

Publication type:

Article

Extended pedigree patterned covariance matrix mixed models for quantitative phenotype analysis.

Published in:

Genetic Epidemiology, 1992, v. 9, n. 2, p. 73, doi. 10.1002/gepi.1370090202

By:

Schork, Nicholas J.;
Vogler, G. P.

Publication type:

Article

Assessment of multiple displacement amplification for polymorphism discovery and haplotype determination at a highly polymorphic locus, MC1R.

Published in:

Human Mutation, 2005, v. 26, n. 2, p. 145, doi. 10.1002/humu.20199

By:

Murthy, Kenton K.;
Mahboubi, Vafa S.;
Santiago, Alicia;
Barragan, Mandy T.;
Knöll, Ralph;
Schultheiss, Heinz-Peter;
O'Connor, Daniel T.;
Schork, Nicholas J.;
Rana, Brinda K.

Publication type:

Article

Prestige centrality-based functional outlier detection in gene expression analysis.

Published in:

Bioinformatics, 2009, v. 25, n. 17, p. 2222, doi. 10.1093/bioinformatics/btp388

By:

Torkamani, Ali;
Schork, Nicholas J.

Publication type:

Article

Predicting functional regulatory polymorphisms.

Published in:

Bioinformatics, 2008, v. 24, n. 16, p. 1787, doi. 10.1093/bioinformatics/btn311

By:

Ali Torkamani;
Nicholas J. Schork

Publication type:

Article

Accurate prediction of deleterious protein kinase polymorphisms.

Published in:

Bioinformatics, 2007, v. 23, n. 21, p. 2918, doi. 10.1093/bioinformatics/btm437

By:

Ali Torkamani;
Nicholas J. Schork

Publication type:

Article

Single‐Cell Patch‐Clamp/Proteomics of Human Alzheimer's Disease iPSC‐Derived Excitatory Neurons Versus Isogenic Wild‐Type Controls Suggests Novel Causation and Therapeutic Targets.

Published in:

Advanced Science, 2024, v. 11, n. 29, p. 1, doi. 10.1002/advs.202400545

By:

Ghatak, Swagata;
Diedrich, Jolene K.;
Talantova, Maria;
Bhadra, Nivedita;
Scott, Henry;
Sharma, Meetal;
Albertolle, Matthew;
Schork, Nicholas J.;
Yates, John R.;
Lipton, Stuart A.

Publication type:

Article

Identifying genes and genetic variation underlying human diseases and complex phenotypes via recombination mapping.

Published in:

Journal of Physiology, 2004, v. 554, n. 1, p. 40, doi. 10.1113/jphysiol.2003.051128

By:

Broeckel, Ulrich;
Schork, Nicholas J.

Publication type:

Article

Pentadecanoic Acid (C15:0), an Essential Fatty Acid, Shares Clinically Relevant Cell-Based Activities with Leading Longevity-Enhancing Compounds.

Published in:

Nutrients, 2023, v. 15, n. 21, p. 4607, doi. 10.3390/nu15214607

By:

Venn-Watson, Stephanie;
Schork, Nicholas J.

Publication type:

Article

A simulation-based analysis of chromosome segment sharing among a group of arbitrarily related individuals.

Published in:

European Journal of Human Genetics, 2007, v. 15, n. 12, p. 1260, doi. 10.1038/sj.ejhg.5201910

By:

Libiger, Ondrej;
Schork, Nicholas J.

Publication type:

Article

The impact of data quality on the identification of complex disease genes: experience from the Family Blood Pressure Program.

Published in:

European Journal of Human Genetics, 2006, v. 14, n. 4, p. 469, doi. 10.1038/sj.ejhg.5201582

By:

Chang, Yen-Pei Christy;
Kim, James Dae-Ok;
Schwander, Karen;
Rao, Dabeeru C.;
Miller, Mike B.;
Weder, Alan B.;
Cooper, Richard S.;
Schork, Nicholas J.;
Province, Michael A.;
Morrison, Alanna C.;
Kardia, Sharon L. R.;
Quertermous, Thomas;
Chakravarti, Aravinda

Publication type:

Article

Single-nucleus and single-cell transcriptomes compared in matched cortical cell types.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0209648

By:

Bakken, Trygve E.;
Hodge, Rebecca D.;
Miller, Jeremy A.;
Yao, Zizhen;
Nguyen, Thuc Nghi;
Aevermann, Brian;
Barkan, Eliza;
Bertagnolli, Darren;
Casper, Tamara;
Dee, Nick;
Garren, Emma;
Goldy, Jeff;
Graybuck, Lucas T.;
Kroll, Matthew;
Lasken, Roger S.;
Lathia, Kanan;
Parry, Sheana;
Rimorin, Christine;
Scheuermann, Richard H.;
Schork, Nicholas J.

Publication type:

Article

Correlation analysis of genetic admixture and social identification with body mass index in a Native American Community.

Published in:

American Journal of Human Biology, 2014, v. 26, n. 3, p. 347, doi. 10.1002/ajhb.22521

By:

Norden‐Krichmar, Trina M.;
Gizer, Ian R.;
Libiger, Ondrej;
Wilhelmsen, Kirk C.;
Ehlers, Cindy L.;
Schork, Nicholas J.

Publication type:

Article

Catapulting clopidogrel pharmacogenomics forward.

Published in:

Nature Medicine, 2011, v. 17, n. 1, p. 40, doi. 10.1038/nm0111-40

By:

Topol, Eric J.;
Schork, Nicholas J.

Publication type:

Article

Not so lost in the genetic crowd.

Published in:

Nature Genetics, 2009, v. 41, n. 11, p. 1163, doi. 10.1038/ng1109-1163

By:

Schork, Nicholas J.;
Bansal, Vikas

Publication type:

Article

The insulin gene VNTR is associated with fasting insulin levels and development of juvenile obesity.

Published in:

Nature Genetics, 2000, v. 26, n. 4, p. 444, doi. 10.1038/82579

By:

Le Stunff, Catherine;
Fallin, Daniele;
Schork, Nicholas J.;
Bougnères, Pierre

Publication type:

Article

Genetic structure of community acquired methicillin-resistant Staphylococcus aureus USA300.

Published in:

BMC Genomics, 2012, v. 13, n. 1, p. 1, doi. 10.1186/1471-2164-13-508

By:

Tewhey, Ryan;
Cannavino, Christopher R.;
Leake, John AD;
Bansal, Vikas;
Topol, Eric J.;
Torkamani, Ali;
Bradley, John S.;
Schork, Nicholas J.

Publication type:

Article

Whole genome sequencing analysis of Plasmodium vivax using whole genome capture.

Published in:

BMC Genomics, 2012, v. 13, n. 1, p. 262, doi. 10.1186/1471-2164-13-262

By:

Bright, A. Taylor;
Tewhey, Ryan;
Abeles, Shira;
Chuquiyauri, Raul;
Llanos-Cuentas, Alejandro;
Ferreira, Marcelo U.;
Schork, Nicholas J.;
Vinetz, Joseph M.;
Winzeler, Elizabeth A

Publication type:

Article

Personalized medicine: Time for one-person trials.

Published in:

2015

By:

Schork, Nicholas J.

Publication type:

Opinion

The Aging Face: A Psychocutaneous Perspective.

Published in:

Journal of Dermatologic Surgery & Oncology, 1990, v. 16, n. 10, p. 902, doi. 10.1111/j.1524-4725.1990.tb01553.x

By:

Gupta, Madhulika A.;
Gupta, Aditya K.;
Schork, Nicholas J.;
Ellis, Charles N.;
Voorhees, John J.

Publication type:

Article

The relationship between 11 different polygenic longevity scores, parental lifespan, and disease diagnosis in the UK Biobank.

Published in:

GeroScience, 2024, v. 46, n. 4, p. 3911, doi. 10.1007/s11357-024-01107-1

By:

Don, Janith;
Schork, Andrew J.;
Glusman, Gwênlyn;
Rappaport, Noa;
Cummings, Steve R.;
Duggan, David;
Raju, Anish;
Hellberg, Kajsa-Lotta Georgii;
Gunn, Sophia;
Monti, Stefano;
Perls, Thomas;
Lapidus, Jodi;
Goetz, Laura H.;
Sebastiani, Paola;
Schork, Nicholas J.

Publication type:

Article

Distribution of 54 polygenic risk scores for common diseases in long lived individuals and their offspring.

Published in:

GeroScience, 2022, v. 44, n. 2, p. 719, doi. 10.1007/s11357-022-00518-2

By:

Gunn, Sophia;
Wainberg, Michael;
Song, Zeyuan;
Andersen, Stacy;
Boudreau, Robert;
Feitosa, Mary F.;
Tan, Qihua;
Montasser, May E.;
O'Connell, Jeffrey R.;
Stitziel, Nathan;
Price, Nathan;
Perls, Thomas;
Schork, Nicholas J.;
Sebastiani, Paola

Publication type:

Article

Report: NIA workshop on translating genetic variants associated with longevity into drug targets.

Published in:

GeroScience, 2018, v. 40, n. 5/6, p. 523, doi. 10.1007/s11357-018-0046-7

By:

Schork, Nicholas J.;
Raghavachari, Nalini;
On behalf of Workshop Speakers and Participants

Publication type:

Article

Emerging therapeutic drug monitoring technologies: considerations and opportunities in precision medicine.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1348112

By:

Liang, Winnie S.;
Beaulieu-Jones, Brett;
Smalley, Susan;
Snyder, Michael;
Goetz, Laura H.;
Schork, Nicholas J.

Publication type:

Article

Treatment Responses to Tooth Whitening in Twins.

Published in:

Twin Research & Human Genetics, 2014, v. 17, n. 1, p. 23, doi. 10.1017/thg.2013.87

By:

Corby, Patricia M. A.;
Biesbrock, Aaron;
Gerlach, Robert;
Corby, Andrea L.;
Moreira, Alexandre;
Schork, Nicholas J.;
Bretz, Walter A.

Publication type:

Article

Environmental and genetic contributions to indicators of oral malodor in twins.

Published in:

2011

By:

Bretz, Walter A.;
Biesbrock, Aaron;
Corby, Patricia M.;
Corby, Andrea L.;
Bretz, Walter G.;
Wessel, Jennifer;
Schork, Nicholas J.

Publication type:

journal article

Heritability of oral microbial species in caries-active and caries-free twins.

Published in:

2007

By:

Corby, Patricia M.;
Bretz, Walter A.;
Hart, Thomas C.;
Schork, Nicholas J.;
Wessel, J.;
Lyons-Weiler, James;
Paster, Bruce J.

Publication type:

journal article

A Weighted Polygenic Risk Score Using 14 Known Susceptibility Variants to Estimate Risk and Age Onset of Psoriasis in Han Chinese.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0125369

By:

Yin, Xianyong;
Cheng, Hui;
Lin, Yan;
Wineinger, Nathan E.;
Zhou, Fusheng;
Sheng, Yujun;
Yang, Chao;
Li, Pan;
Li, Feng;
Shen, Changbing;
Yang, Sen;
Schork, Nicholas J.;
Zhang, Xuejun

Publication type:

Article

Scripps Genome ADVISER: Annotation and Distributed Variant Interpretation SERver.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0116815

By:

Pham, Phillip H.;
Shipman, William J.;
Erikson, Galina A.;
Schork, Nicholas J.;
Torkamani, Ali

Publication type:

Article

The Dental Plaque Microbiome in Health and Disease.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058487

By:

Peterson, Scott N.;
Snesrud, Erik;
Liu, Jia;
Ong, Ana C.;
Kilian, Mogens;
Schork, Nicholas J.;
Bretz, Walter

Publication type:

Article

Genetic Profiling Using Genome-Wide Significant Coronary Artery Disease Risk Variants Does Not Improve the Prediction of Subclinical Atherosclerosis: The Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey - A Meta-Analysis of Three Independent Studies

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0028931

By:

Hernesniemi, Jussi A.;
Seppälä, Ilkka;
Lyytikäinen, Leo-Pekka;
Mononen, Nina;
Oksala, Niku;
Hutri-Kähönen, Nina;
Juonala, Markus;
Taittonen, Leena;
Smith, Erin N.;
Schork, Nicholas J.;
Wei Chen;
Srinivasan, Sathanur R.;
Berenson, Gerald S.;
Murray, Sarah S.;
Laitinen, Tomi;
Jula, Antti;
Kettunen, Johannes;
Ripatti, Samuli;
Laaksonen, Reijo;
Viikari, Jorma

Publication type:

Article

Efficient and Cost Effective Population Resequencing by Pooling and In-Solution Hybridization.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0018353

By:

Bansal, Vikas;
Tewhey, Ryan;
LeProust, Emily M.;
Schork, Nicholas J.

Publication type:

Article

Sequence and Structure Signatures of Cancer Mutation Hotspots in Protein Kinases.

Published in:

PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007485

By:

Dixit, Anshuman;
Lin Yi;
Gowthaman, Ragul;
Torkamani, Ali;
Schork, Nicholas J.;
Verkhivker, Gennady M.

Publication type:

Article

Mixture distributions in human genetics research.

Published in:

1996

By:

Schork, Nicholas J;
Allison, David B;
Thiel, Bonnie;
Schork, N J;
Allison, D B;
Thiel, B

Publication type:

journal article

Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis.

Published in:

2005

By:

An, Ping;
Freedman, Barry I;
Hanis, Craig L;
Chen, Yii-Der I;
Weder, Alan B;
Schork, Nicholas J;
Boerwinkle, Eric;
Province, Michael A;
Hsiung, Chao Agnes;
Wu, Xiaodong;
Quertermous, Thomas;
Rao, D C

Publication type:

journal article

Genome-wide Linkage Scans for Fasting Glucose, Insulin, and Insulin Resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program.

Published in:

Diabetes, 2005, v. 54, n. 3, p. 909

By:

Ping An;
Freedman, Barry I.;
Hanis, Craig L.;
Chen, Yii-Der I.;
Weder, Alan B.;
Schork, Nicholas J.;
Boerwinkle, Eric;
Province, Michael A.;
Hsiung, Chao Agnes;
Xiaodong Wu;
Quertermous, Thomas;
Rao, D. C.

Publication type:

Article

A Common Promoter Variant of the Leptin Gene Is Associated With Changes in the Relationship...

Published in:

Diabetes, 2000, v. 49, n. 12, p. 2196, doi. 10.2337/diabetes.49.12.2196

By:

Stunff, Catherine Le;
Bihan, Christine Le;
Schork, Nicholas J.;
Bougneres, Pierre

Publication type:

Article

Genetic Analysis of NIDDM.

Published in:

Diabetes, 1996, v. 45, n. 1, p. 1, doi. 10.2337/diab.45.1.1

By:

Ghosh, Soumitra;
Schork, Nicholas J.

Publication type:

Article

Crosses of NOD mice with the related NON strain. A polygenic model for IDDM.

Published in:

1995

By:

McAleer, Marcia A.;
Reifsnyder, Peter;
Palmer, Sheila M.;
Prochazka, Michal;
Love, Jennifer M.;
Copeman, James B.;
Powell, Elizabeth E.;
Rodrigues, Nanda R.;
Prins, Jan-Bas;
Serreze, David V.;
DeLarato, Nicole H.;
Wicker, Linda S.;
Peterson, Laurence B.;
Schork, Nicholas J.;
Todd, John A.;
Leiter, Edward H.;
McAleer, M A;
Reifsnyder, P;
Palmer, S M;
Prochazka, M

Publication type:

journal article

On the asymmetry of biological frequency distributions.

Published in:

Genetic Epidemiology, 1990, v. 7, n. 6, p. 427, doi. 10.1002/gepi.1370070605

By:

Schork, Nicholas J.;
Weder, Alan B.;
Schork, M. Anthony;
Rao, D. C.

Publication type:

Article

Borrelia PeptideAtlas: A proteome resource of common Borrelia burgdorferi isolates for Lyme research.

Published in:

Scientific Data, 2024, v. 11, n. 1, p. 1, doi. 10.1038/s41597-024-04047-9

By:

Reddy, Panga J.;
Sun, Zhi;
Wippel, Helisa H.;
Baxter, David H.;
Swearingen, Kristian;
Shteynberg, David D.;
Midha, Mukul K.;
Caimano, Melissa J.;
Strle, Klemen;
Choi, Yongwook;
Chan, Agnes P.;
Schork, Nicholas J.;
Varela-Stokes, Andrea S.;
Moritz, Robert L.

Publication type:

Article

Touch Deprivation Has an Adverse Effect on Body Image: Some Preliminary Observations.

Published in:

International Journal of Eating Disorders, 1995, v. 17, n. 2, p. 185, doi. 10.1002/1098-108X(199503)17:2<185::AID-EAT2260170212>3.0.CO;2-0

By:

Gupta, Madhulika A.;
Schork, Nicholas J.

Publication type:

Article

Aging-Related Concerns and Body Image: Possible Future Implications for Eating Disorders.

Published in:

International Journal of Eating Disorders, 1993, v. 14, n. 4, p. 481, doi. 10.1002/1098-108X(199312)14:4<481::AID-EAT2260140411>3.0.CO;2-G

By:

Gupta, Madhulika A.;
Schork, Nicholas J.

Publication type:

Article

Partial Least Squares Regression Can Aid in Detecting Differential Abundance of Multiple Features in Sets of Metagenomic Samples.

Published in:

Frontiers in Genetics, 2015, p. 1, doi. 10.3389/fgene.2015.00350

By:

Libiger, Ondrej;
Schork, Nicholas J.

Publication type:

Article

Functional expression of dental plaque microbiota.

Published in:

Frontiers in Cellular & Infection Microbiology, 2014, p. 1, doi. 10.3389/fcimb.2014.00108

By:

Peterson, Scott N.;
Meissner, Tobias;
Su, Andrew I.;
Snesrud, Erik;
Ong, Ana C.;
Schork, Nicholas J.;
Bretz, Walter A.;
Banas, Jeff;
Iebba, Valerio

Publication type:

Article

Variants Near CCK Receptors are Associated With Electrophysiological Responses to Pre-pulse Startle Stimuli in a Mexican American Cohort.

Published in:

2015

By:

Norden-Krichmar, Trina M.;
Gizer, Ian R.;
Phillips, Evelyn;
Wilhelmsen, Kirk C.;
Schork, Nicholas J.;
Ehlers, Cindy L.

Publication type:

journal article