Works by Nian-Guang Li

Results: 33

Development of novel 9-O-substituted-13-octylberberine derivatives as potential anti-hepatocellular carcinoma agents.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 2423, doi. 10.1080/14756366.2022.2118268

By:

Jichao Chen;
Yiping Duan;
Xiaoxuan Yu;
Jiarou Zhong;
Jing Bai;
Nian-Guang Li;
Zheying Zhu;
Jinyi Xu

Publication type:

Article

Novel multitarget-directed tacrine derivatives as potential candidates for the treatment of Alzheimer’s disease.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 572, doi. 10.1080/14756366.2016.1210139

By:

Wu, Wen-Yu;
Dai, Yu-Chen;
Li, Nian-Guang;
Dong, Ze-Xi;
Gu, Ting;
Shi, Zhi-Hao;
Xue, Xin;
Tang, Yu-Ping;
Duan, Jin-Ao

Publication type:

Article

Cascade Reaction and Synthesis of Bicyclo[2,2,2]octenones.

Published in:

Chinese Journal of Chemistry, 2008, v. 26, n. 2, p. 363, doi. 10.1002/cjoc.200890070

By:

LI, Nian-Guang;
WANG, Jin-Xin;
YOU, Qi-Dong;
CHU, Gang;
GUO, Qing-Long

Publication type:

Article

A New and Practical Synthetic Method for the Synthesis of 6-O-Methyl-scutellarein: One Metabolite of Scutellarin in Vivo.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 4, p. 7587, doi. 10.3390/ijms16047587

By:

Hang Lin;
Wei Zhang;
Ze-Xi Dong;
Ting Gu;
Nian-Guang Li;
Zhi-Hao Shi;
Jun Kai;
Cheng Qu;
Guan-Xiong Shang;
Yu-Ping Tang;
Fang Fang;
He-Min Li;
Jian-Ping Yang;
Jin-Ao Duan

Publication type:

Article

Synthesis and Bio-Activity Evaluation of Scutellarein as a Potent Agent for the Therapy of Ischemic Cerebrovascular Disease.

Published in:

International Journal of Molecular Sciences, 2011, v. 12, n. 11, p. 8208, doi. 10.3390/ijms12118208

By:

Li-Hua Qian;
Nian-Guang Li;
Yu-Ping Tang;
Li Zhang;
Hao Tang;
Zhen-Jiang Wang;
Li Liu;
Shu-Lin Song;
Jian-Ming Guo;
An-Wei Ding

Publication type:

Article

Investigation of 6- O -methyl-scutellarein metabolites in rats by ultra-flow liquid chromatography/quadrupole-time-of-flight mass spectrometry.

Published in:

Pharmaceutical Biology, 2016, v. 54, n. 10, p. 2158, doi. 10.3109/13880209.2016.1149495

By:

Zhang, Wei;
Li, Nian-Guang;
Tang, Yu-Ping;
Dong, Ze-Xi;
Gu, Ting;
Wu, Wen-Yu;
Zhang, Peng-Xuan;
Yu, Shao-Peng;
Duan, Jin-Ao;
Shi, Zhi-Hao

Publication type:

Article

Protective effect of 6-O-methyl-scutellarein on repeated cerebral ischemia/reperfusion in rats.

Published in:

Journal of Asian Natural Products Research, 2018, v. 20, n. 12, p. 1167, doi. 10.1080/10286020.2017.1383396

By:

Wu, Wen-Yu;
Zhong, Yue;
Lu, Yu-Ting;
Sun, Ying;
Li, Nian-Guang;
Shi, Zhi-Hao;
Dong, Ze-Xi;
Gu, Ting;
Xue, Xin;
Fang, Fang;
Li, He-Min;
Tang, Yu-Ping;
Duan, Jin-Ao

Publication type:

Article

Investigation on the interactions of scutellarin and scutellarein with bovine serum albumin using spectroscopic and molecular docking techniques.

Published in:

Archives of Pharmacal Research, 2015, v. 38, n. 10, p. 1789, doi. 10.1007/s12272-014-0541-z

By:

Tang, Hao;
Shi, Zhi-Hao;
Li, Nian-Guang;
Tang, Yu-Ping;
Shi, Qian-Ping;
Dong, Ze-Xi;
Zhang, Peng-Xuan;
Duan, Jin-Ao

Publication type:

Article

Synthetic strategies in the construction of chromones.

Published in:

Journal of Heterocyclic Chemistry, 2010, v. 47, n. 4, p. 785, doi. 10.1002/jhet.393

By:

Nian-Guang Li;
Zhi-Hao Shi;
Yu-Ping Tang;
Hong-Yue Ma;
Jian-Ping Yang;
Bao-Quan Li;
Zhen-Jiang Wang;
Shu-Lin Song;
Jin-Ao Duan

Publication type:

Article

Design, synthesis, and biological activity evaluation of BACE1 inhibitors with antioxidant activity.

Published in:

Drug Development Research, 2020, v. 81, n. 2, p. 206, doi. 10.1002/ddr.21585

By:

Li, He‐Min;
Yu, Shao‐Peng;
Fan, Tian‐Yuan;
Zhong, Yue;
Gu, Ting;
Wu, Wen‐Yu;
Zhao, Chao;
Chen, Zhi;
Chen, Min;
Li, Nian‐Guang;
Wang, Xiao‐Long

Publication type:

Article

Biological Evaluation and SAR Analysis of O-Methylated Analogs of Quercetin as Inhibitors of Cancer Cell Proliferation.

Published in:

Drug Development Research, 2014, v. 75, n. 7, p. 455, doi. 10.1002/ddr.21181

By:

Shi, Zhi ‐ Hao;
Li, Nian ‐ Guang;
Tang, Yu ‐ Ping;
Shi, Qian ‐ Ping;
Tang, Hao;
Li, Wei;
Zhang, Xu;
Fu, Hai ‐ An;
Duan, Jin ‐ Ao

Publication type:

Article

Design, Synthesis and Biological Evaluation of Caffeic Acid Amides as Selective MMP-2 and MMP-9 Inhibitors.

Published in:

Drug Development Research, 2012, v. 73, n. 6, p. 343, doi. 10.1002/ddr.21038

By:

Shi, Zhi-Hao;
Li, Nian-Guang;
Shi, Qian-Ping;
Tang, Hao;
Tang, Yu-Ping;
Li, Wei;
Yin, Lian;
Yang, Jian-Ping;
Duan, Jin-Ao

Publication type:

Article

Design, Synthesis, and Preliminary Evaluation of Substituted Cinnamic Acid Esters as Selective Matrix Metalloproteinase Inhibitors.

Published in:

Drug Development Research, 2012, v. 73, n. 6, p. 317, doi. 10.1002/ddr.21015

By:

Shi, Zhi-Hao;
Li, Nian-Guang;
Shi, Qian-Ping;
Hao-Tang;
Tang, Yu-Ping

Publication type:

Article

Design and synthesis of novel NO-donor-ferulic acid hybrids as potential antiatherosclerotic drug candidates.

Published in:

Drug Development Research, 2011, v. 72, n. 5, p. 405, doi. 10.1002/ddr.20442

By:

Li, Nian-Guang;
Wang, Rong;
Shi, Zhi-Hao;
Tang, Yu-Ping;
Li, Bao-Quan;
Wang, Zhen-Jiang;
Song, Shu-Lin;
Qian, Li-Hua;
Wei, Li;
Yang, Jian-Ping;
Yao, Li-Juan;
Xi, Jun-Zuan;
Xu, Jia;
Feng, Feng;
Qian, Da-Wei;
Duan, Jin-Ao

Publication type:

Article

Targeting the development of resveratrol as a chemopreventive agent.

Published in:

Drug Development Research, 2010, v. 71, n. 6, p. 335, doi. 10.1002/ddr.20380

By:

Li, Nian-Guang;
Shi, Zhi-Hao;
Tang, Yu-Ping;
Yang, Jian-Ping;
Wang, Zhen-Jiang;
Song, Shu-Lin;
Lu, Tu-Lin;
Duan, Jin-Ao

Publication type:

Article

An improved synthesis of 6-o-methyl-scutellarein through selective benzylation.

Published in:

Journal of Chemical Research, 2015, v. 39, n. 11, p. 674, doi. 10.3184/174751915X14452625043383

By:

Zhang, Wei;
Dong, Ze-Xi;
Gu, Ting;
Li, Nian-Guang;
Wu, Wen-Yu;
Zhang, Peng-Xuan;
Tang, Yu-Ping;
Yang, Jian-Ping;
Xue, Xin;
Fang, Fang;
Li, He-Min;
Cheng, Hai-Bo;
Duan, Jin-Ao;
Shi, Zhi-Hao

Publication type:

Article

Recent opportunities in matrix metalloproteinase inhibitor drug design for cancer.

Published in:

Expert Opinion on Drug Discovery, 2018, v. 13, n. 1, p. 75, doi. 10.1080/17460441.2018.1398732

By:

Zhong, Yue;
Lu, Yu-Ting;
Sun, Ying;
Shi, Zhi-Hao;
Li, Nian-Guang;
Tang, Yu-Ping;
Duan, Jin-Ao

Publication type:

Article

An Efficient Chemical Synthesis of Scutellarein: An in Vivo Metabolite of Scutellarin.

Published in:

Molecules, 2016, v. 21, n. 3, p. 263, doi. 10.3390/molecules21030263

By:

Ze-Xi Dong;
Nian-Guang Li;
Peng-Xuan Zhang;
Ting Gu;
Wen-Yu Wu;
Zhi-Hao Shi

Publication type:

Article

Development of Orally Active Thrombin Inhibitors for the Treatment of Thrombotic Disorder Diseases.

Published in:

Molecules, 2015, v. 20, n. 6, p. 11046, doi. 10.3390/molecules200611046

By:

Li-Wei He;
Wei-Chen Dai;
Nian-Guang Li

Publication type:

Article

A New and Efficient Synthesis of 6-O-Methylscutellarein, the Major Metabolite of the Natural Medicine Scutellarin.

Published in:

Molecules, 2015, v. 20, n. 6, p. 10184, doi. 10.3390/molecules200610184

By:

Wei Zhang;
Ze-Xi Dong;
Ting Gu;
Nian-Guang Li;
Peng-Xuan Zhang;
Wen-Yu Wu;
Shao-Peng Yu;
Yu-Ping Tang;
Jian-Ping Yang;
Zhi-Hao Shi

Publication type:

Article

Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives.

Published in:

Molecules, 2014, v. 19, n. 10, p. 16458, doi. 10.3390/molecules191016458

By:

Pengxuan Zhang;
Yuping Tang;
Nian-Guang Li;
Yue Zhu;
Jin-Ao Duan

Publication type:

Article

Synthesis and Protective Effect of Scutellarein on Focal Cerebral Ischemia/Reperfusion in Rats.

Published in:

Molecules, 2012, v. 17, n. 9, p. 10667, doi. 10.3390/molecules170910667

By:

Lihua Qian;
Minzhe Shen;
Hao Tang;
Yuping Tang;
Li Zhang;
Yifan Fu;
Qianping Shi;
Nian-Guang Li

Publication type:

Article

Highly Efficient Esterification of Ferulic Acid Under Microwave Irradiation.

Published in:

Molecules, 2009, v. 14, n. 6, p. 2118, doi. 10.3390/molecules14062118

By:

Nian-Guang Li;
Zhi-Hao Shi;
Yu-Ping Tang;
Bao-Quan L;
Jin-Ao Duan

Publication type:

Article

Design, Synthesis, and In Vitro Antiplatelet Aggregation Activities of Ferulic Acid Derivatives.

Published in:

Journal of Chemistry, 2015, v. 2015, p. 1, doi. 10.1155/2015/376527

By:

Zhang, Peng-Xuan;
Lin, Hang;
Qu, Cheng;
Tang, Yu-Ping;
Li, Nian-Guang;
Kai, Jun;
Shang, Guanxiong;
Li, Baoquan;
Zhang, Li;
Yan, Hui;
Liu, Pei;
Duan, Jin-Ao

Publication type:

Article

Comparative Metabolomic Analysis of the Neuroprotective Effects of Scutellarin and Scutellarein against Ischemic Insult.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0131569

By:

Tang, Hao;
Tang, Yuping;
Li, Nian-Guang;
Lin, Hang;
Li, Weixia;
Shi, Qianping;
Zhang, Wei;
Zhang, Pengxuan;
Dong, Zexi;
Shen, Minzhe;
Gu, Ting;
Duan, Jin-Ao

Publication type:

Article

Metabolite Profiling of Danatinib in Mice Using Ultra‐High‐Performance Liquid Chromatography/Tandem Mass Spectrometry In Vitro and In Vivo.

Published in:

Biomedical Chromatography, 2025, v. 39, n. 3, p. 1, doi. 10.1002/bmc.70022

By:

Zhang, Meng‐Yuan;
Zhang, Yuan‐Wei;
Yu, Sheng‐Nan;
Qiao, Nuo;
Ni, Xing‐Feng;
Liu, Qian;
Bai, Ming‐Yu;
Li, Qing‐Qing;
Wang, Zi‐Xuan;
Zhou, Yun;
Ding, Ning;
Sun, Shan‐Liang;
Xue, Xin;
Shan, Chen‐Xiao;
Shi, Zhi‐Hao;
Wang, Jin;
Li, Nian‐Guang

Publication type:

Article

Insight into Janus kinases specificity: From molecular architecture to cancer therapeutics.

Published in:

Medcomm: Oncology, 2024, v. 3, n. 1, p. 1, doi. 10.1002/mog2.69

By:

Wei, Tian‐Hua;
Lu, Meng‐Yi;
Yao, Si‐Hui;
Hong, Yu‐Qi;
Yang, Jin;
Zhang, Meng‐Yuan;
Yin, Yu‐Qi;
Han, Yu‐Jie;
Li, Qing‐Qing;
Wang, Zi‐Xuan;
Wang, Yi‐Bo;
Tong, Zhen‐Jiang;
Zhou, Yun;
Dai, Wei‐Chen;
Yu, Yan‐Cheng;
Sun, Shan‐Liang;
Yang, Ye;
Li, Nian‐Guang;
Shi, Zhi‐Hao

Publication type:

Article

RETRACTED: Yue et al. A Ferulic Acid Derivative FXS-3 Inhibits Proliferation and Metastasis of Human Lung Cancer A549 Cells via Positive JNK Signaling Pathway and Negative ERK/p38, AKT/mTOR and MEK/ERK Signaling Pathways. Molecules 2019, 24 , 2165.

Published in:

2025

By:

Yue, Shi-Jun;
Zhang, Peng-Xuan;
Zhu, Yue;
Li, Nian-Guang;
Chen, Yan-Yan;
Li, Jia-Jia;
Zhang, Sai;
Jin, Ru-Yi;
Yan, Hao;
Shi, Xu-Qin;
Tang, Yu-Ping;
Duan, Jin-Ao

Publication type:

Correction Notice

A Ferulic Acid Derivative FXS-3 Inhibits Proliferation and Metastasis of Human Lung Cancer A549 Cells via Positive JNK Signaling Pathway and Negative ERK/p38, AKT/mTOR and MEK/ERK Signaling Pathways.

Published in:

Molecules, 2019, v. 24, n. 11, p. 2165, doi. 10.3390/molecules24112165

By:

Yue, Shi-Jun;
Zhang, Peng-Xuan;
Zhu, Yue;
Li, Nian-Guang;
Chen, Yan-Yan;
Li, Jia-Jia;
Zhang, Sai;
Jin, Ru-Yi;
Yan, Hao;
Shi, Xu-Qin;
Tang, Yu-Ping;
Duan, Jin-Ao

Publication type:

Article

Synthesis and Bioactivity Characterization of Scutellarein Sulfonated Derivative.

Published in:

Molecules, 2017, v. 22, n. 6, p. 1028, doi. 10.3390/molecules22061028

By:

Ting Gu;
Yue Zhong;
Yu-Ting Lu;
Ying Sun;
Ze-Xi Dong;
Wen-Yu Wu;
Zhi-Hao Shi;
Nian-Guang Li;
Xin Xue;
Fang Fang;
He-Min Li;
Yu-Ping Tang

Publication type:

Article

Development and Structural Modification of BACE1 Inhibitors.

Published in:

Molecules, 2017, v. 22, n. 1, p. 4, doi. 10.3390/molecules22010004

By:

Ting Gu;
Wen-Yu Wu;
Ze-Xi Dong;
Shao-Peng Yu;
Ying Sun;
Yue Zhong;
Yu-Ting Lu;
Nian-Guang Li

Publication type:

Article

Studies on the Protective Effects of Scutellarein against Neuronal Injury by Ischemia through the Analysis of Endogenous Amino Acids and Ca<sup>2+</sup> Concentration Together with Ca<sup>2+</sup>-ATPase Activity.

Published in:

Journal of Chemistry, 2015, v. 2015, p. 1, doi. 10.1155/2015/497842

By:

Tang, Hao;
Dong, Ze-Xi;
Gu, Ting;
Li, Nian-Guang;
Tang, Yu-Ping;
Shi, Qian-Ping;
Guo, Jian-Ming;
Zhang, Peng-Xuan;
Duan, Jin-Ao

Publication type:

Article

Design, Synthesis, and Biological Evaluation of Scutellarein Derivatives Based on Scutellarin Metabolic Mechanism In Vivo.

Published in:

Chemical Biology & Drug Design, 2016, v. 87, n. 6, p. 946, doi. 10.1111/cbdd.12727

By:

Dong, Ze ‐ Xi;
Shi, Zhi ‐ Hao;
Li, Nian ‐ Guang;
Zhang, Wei;
Gu, Ting;
Zhang, Peng ‐ Xuan;
Wu, Wen ‐ Yu;
Tang, Yu ‐ Ping;
Fang, Fang;
Xue, Xin;
Li, He ‐ Min;
Cheng, Hai ‐ Bo;
Yang, Jian ‐ Ping;
Duan, Jin ‐ Ao

Publication type:

Article