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Investigation of matrix effects in bioanalytical high-performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery.
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- Rapid Communications in Mass Spectrometry: RCM, 2003, v. 17, n. 1, p. 97, doi. 10.1002/rcm.876
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- Article
Direct analysis of drug candidates in tissue by matrix-assisted laser desorption/ionization mass spectrometry.
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- Journal of Mass Spectrometry, 2003, v. 38, n. 10, p. 1081
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- Article
Simultaneous determination of a drug candidate and its metabolite in rat plasma samples using ultrafast monolithic column high-performance liquid chromatography/tandem mass spectrometry.
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- Rapid Communications in Mass Spectrometry: RCM, 2002, v. 16, n. 10, p. 944, doi. 10.1002/rcm.648
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- Article
Quantitative screening and matrix effect studies of drug discovery compounds in monkey plasma using fast-gradient liquid chromatography/tandem mass spectrometry.
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- Rapid Communications in Mass Spectrometry: RCM, 2001, v. 15, n. 24, p. 2481, doi. 10.1002/rcm.479
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- Article
Cassette-accelerated rapid rat screen: a systematic procedure for the dosing and liquid chromatography/atmospheric pressure ionization tandem mass spectrometric analysis of new chemical entities as part of new drug discovery.
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- Rapid Communications in Mass Spectrometry: RCM, 2001, v. 15, n. 5, p. 335, doi. 10.1002/rcm.235
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- Article
In vitro metabolism of 10-(3-chlorophenyl)-6,8,9,10-tetrahydrobenzo[b][1,8]naphthyridin-5(7H)-one, a topical antipsoriatic agent. Use of precision-cut rat, dog, monkey and human liver slices, and chemical synthesis of metabolites.
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- Biopharmaceutics & Drug Disposition, 1998, v. 19, n. 5, p. 315, doi. 10.1002/(SICI)1099-081X(199807)19:5<315::AID-BDD107>3.0.CO;2-N
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- Article
High-throughput cassette assay for drug stability measurement in plasma using direct HPLC-MS/MS.
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- Spectroscopy: An International Journal, 2003, v. 17, n. 2/3, p. 511, doi. 10.1155/2003/657571
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- Article