OpenURL Connection Search

Select item for more details and to access through your institution.

The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response.
Published in:
EMBO Reports, 2008, v. 9, n. 9, p. 930, doi. 10.1038/embor.2008.136
By:
- Friedman, Constantin S;
- O'Donnell, Marie Anne;
- Legarda-Addison, Diana;
- Ng, Aylwin;
- Cárdenas, Washington B;
- Yount, Jacob S;
- Moran, Thomas M;
- Basler, Christopher F;
- Komuro, Akihiko;
- Horvath, Curt M;
- Xavier, Ramnik;
- Ting, Adrian T
Publication type:
Article
Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62.
Published in:
eLife, 2016, p. 1, doi. 10.7554/eLife.17290
By:
- DeJesus, Rowena;
- Moretti, Francesca;
- McAllister, Gregory;
- Zuncai Wang;
- Bergman, Phil;
- Shanming Liu;
- Frias, Elizabeth;
- Alford, John;
- Reece-Hoyes, John S.;
- Lindeman, Alicia;
- Kelliher, Jennifer;
- Russ, Carsten;
- Knehr, Judith;
- Carbone, Walter;
- Beibel, Martin;
- Roma, Guglielmo;
- Ng, Aylwin;
- Tallarico, John A.;
- Porter, Jeffery A.;
- Xavier, Ramnik J.
Publication type:
Article
Regulation of Peripheral Inflammation by a Non-Viable, Non-Colonizing Strain of Commensal Bacteria.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.768076
By:
- Ramani, Kritika;
- Cormack, Taylor;
- Cartwright, Adam N. R.;
- Alami, Aula;
- Parameswaran, Pooja;
- Abdou, Marynawal;
- Wang, Iris;
- Hilliard-Barth, Kristie;
- Argueta, Shannon;
- Raghunathan, Divya;
- Caffry, Will;
- Davitt, Christopher J. H.;
- Romano, Fabian B.;
- Ng, Aylwin;
- Kravitz, Valeria;
- Rommel, Tyler;
- Sizova, Maria;
- Kiran, Esra Uckun;
- Pradeep, Pallavi;
- Ponichtera, Holly E.
Publication type:
Article
Resources for integrative systems biology: from data through databases to networks and dynamic system models.
Published in:
Briefings in Bioinformatics, 2006, v. 7, n. 4, p. 318, doi. 10.1093/bib/bbl036
By:
- Ng, Aylwin;
- Bursteinas, Borisas;
- Qiong Gao;
- Mollison, Ewan;
- Zvelebil, Marketa
Publication type:
Article
Integrative systems biology and networks in autophagy.
Published in:
Seminars in Immunopathology, 2010, v. 32, n. 4, p. 355, doi. 10.1007/s00281-010-0225-9
By:
- Ng, Aylwin C. Y.
Publication type:
Article
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43.
Published in:
Nature, 2009, v. 461, n. 7268, p. 1282, doi. 10.1038/nature08530
By:
- Maslowski, Kendle M.;
- Vieira, Angelica T.;
- Ng, Aylwin;
- Kranich, Jan;
- Sierro, Frederic;
- Di Yu;
- Schilter, Heidi C.;
- Rolph, Michael S.;
- Mackay, Fabienne;
- Artis, David;
- Xavier, Ramnik J.;
- Teixeira, Mauro M.;
- Mackay, Charles R.
Publication type:
Article
RNA interference screen for human genes associated with West Nile virus infection.
Published in:
Nature, 2008, v. 455, n. 7210, p. 242, doi. 10.1038/nature07207
By:
- Krishnan, Manoj N.;
- Ng, Aylwin;
- Sukumaran, Bindu;
- Gilfoy, Felicia D.;
- Uchil, Pradeep D.;
- Sultana, Hameeda;
- Brass, Abraham L.;
- Adametz, Rachel;
- Tsui, Melody;
- Feng Qian;
- Montgomery, Ruth R.;
- Lev, Sima;
- Mason, Peter W.;
- Koski, Raymond A.;
- Elledge, Stephen J.;
- Xavier, Ramnik J.;
- Agaisse, Herve;
- Fikrig, Erol
Publication type:
Article
Caspase 8 inhibits programmed necrosis by processing CYLD.
Published in:
Nature Cell Biology, 2011, v. 13, n. 12, p. 1437, doi. 10.1038/ncb2362
By:
- O'Donnell, Marie Anne;
- Perez-Jimenez, Eva;
- Oberst, Andrew;
- Ng, Aylwin;
- Massoumi, Ramin;
- Xavier, Ramnik;
- Green, Douglas R.;
- Ting, Adrian T.
Publication type:
Article
pSTIING: a ‘systems’ approach towards integrating signalling pathways, interaction and transcriptional regulatory networks in inflammation and cancer.
Published in:
Nucleic Acids Research, 2006, v. 34, n. suppl 1, p. d527
By:
- Ng, Aylwin;
- Bursteinas, Borisas;
- Gao, Qiong;
- Mollison, Ewan;
- Zvelebil, Marketa
Publication type:
Article
Regulation of the H19 imprinting gene expression in human nasopharyngeal carcinoma by methylation.
Published in:
International Journal of Cancer, 2003, v. 104, n. 2, p. 179, doi. 10.1002/ijc.10926
By:
- Ng, Aylwin;
- Tang, Jing P.;
- Goh, Christopher H.K.;
- Hui, Kam M.
Publication type:
Article
Erratum: E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.
Published in:
Nature Communications, 2017, v. 8, n. 8, p. 16141, doi. 10.1038/ncomms16141
By:
- Bist, Pradeep;
- Cheong, Wan Shoo;
- Ng, Aylwin;
- Dikshit, Neha;
- Kim, Bae Hoon;
- Pulloor, Niyas Kudukkil;
- Khameneh, Hanif Javanmard;
- Hedl, Matija;
- Shenoy, Avinash R.;
- Balamuralidhar, Vanniarajan;
- Malik, Najib Bin Abdul;
- Hong, Michelle;
- Neutzner, Albert;
- Chin, Keh-Chuang;
- Kobayashi, Koichi S.;
- Bertoletti, Antonio;
- Mortellaro, Alessandra;
- Abraham, Clara;
- MacMicking, John D.;
- Xavier, Ramnik J.
Publication type:
Article
E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.
Published in:
Nature Communications, 2017, v. 8, n. 6, p. 15865, doi. 10.1038/ncomms15865
By:
- Bist, Pradeep;
- Cheong, Wan Shoo;
- Ng, Aylwin;
- Dikshit, Neha;
- Kim, Bae-Hoon;
- Pulloor, Niyas Kudukkil;
- Khameneh, Hanif Javanmard;
- Hedl, Matija;
- Shenoy, Avinash R.;
- Balamuralidhar, Vanniarajan;
- Malik, Najib Bin Abdul;
- Hong, Michelle;
- Neutzner, Albert;
- Chin, Keh-Chuang;
- Kobayashi, Koichi S.;
- Bertoletti, Antonio;
- Mortellaro, Alessandra;
- Abraham, Clara;
- MacMicking, John D.;
- Xavier, Ramnik J.
Publication type:
Article
Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst.
Published in:
Nature Communications, 2015, v. 6, n. 7, p. 7838, doi. 10.1038/ncomms8838
By:
- Graham, Daniel B.;
- Becker, Christine E.;
- Doan, Aivi;
- Goel, Gautam;
- Villablanca, Eduardo J.;
- Knights, Dan;
- Mok, Amanda;
- Ng, Aylwin C.Y.;
- Doench, John G.;
- Root, David E.;
- Clish, Clary B.;
- Xavier, Ramnik J.
Publication type:
Article
Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans.
Published in:
Nature Communications, 2013, v. 4, n. 1, p. 1342, doi. 10.1038/ncomms2343
By:
- Smeekens, Sanne P.;
- Ng, Aylwin;
- Kumar, Vinod;
- Johnson, Melissa D.;
- Plantinga, Theo S.;
- van Diemen, Cleo;
- Arts, Peer;
- Verwiel, Eugène T. P.;
- Gresnigt, Mark S.;
- Fransen, Karin;
- van Sommeren, Suzanne;
- Oosting, Marije;
- Cheng, Shih-Chin;
- Joosten, Leo A. B.;
- Hoischen, Alexander;
- Kullberg, Bart-Jan;
- Scott, William K.;
- Perfect, John R.;
- van der Meer, Jos W. M.;
- Wijmenga, Cisca
Publication type:
Article
Allergic asthma is distinguished by sensitivity of allergen-specific CD4<sup>+</sup> T cells and airway structural cells to type 2 inflammation.
Published in:
Science Translational Medicine, 2016, v. 8, n. 359, p. 1, doi. 10.1126/scitranslmed.aag1370
By:
- Cho, Josalyn L.;
- Ling, Morris F.;
- Adams, David C.;
- Faustino, Lucas;
- Islam, Sabina A.;
- Afshar, Roshi;
- Griffith, Jason W.;
- Harris, Robert S.;
- Aylwin Ng;
- Radicioni, Giorgia;
- Ford, Amina A.;
- Han, Andre K.;
- Xavier, Ramnik;
- Kwok, William W.;
- Boucher, Richard;
- Moon, James J.;
- Hamilos, Daniel L.;
- Kesimer, Mehmet;
- Suter, Melissa J.;
- Medoff, Benjamin D.
Publication type:
Article
Autophagy Controls BCG-Induced Trained Immunity and the Response to Intravesical BCG Therapy for Bladder Cancer.
Published in:
PLoS Pathogens, 2014, v. 10, n. 10, p. 1, doi. 10.1371/journal.ppat.1004485
By:
- Buffen, Kathrin;
- Oosting, Marije;
- Quintin, Jessica;
- Ng, Aylwin;
- Kleinnijenhuis, Johanneke;
- Kumar, Vinod;
- van de Vosse, Esther;
- Wijmenga, Cisca;
- van Crevel, Reinout;
- Oosterwijk, Egbert;
- Grotenhuis, Anne J.;
- Vermeulen, Sita H.;
- Kiemeney, Lambertus A.;
- van de Veerdonk, Frank L.;
- Chamilos, Georgios;
- Xavier, Ramnik J.;
- van der Meer, Jos W. M.;
- Netea, Mihai G.;
- Joosten, Leo A. B.
Publication type:
Article
Ubiquitin accumulation in autophagy-deicient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection.
Published in:
Journal of Cell Biology, 2010, v. 191, n. 3, p. 537, doi. 10.1083/jcb.201005012
By:
- Riley, Brigit E.;
- Kaiser, Stephen E.;
- Shaler, Thomas A.;
- Ng, Aylwin C. Y.;
- Hara, Taichi;
- Hipp, Mark S.;
- Lage, Kasper;
- Xavier, Ramnik J.;
- Kwon-Yul Ryu;
- Taguchi, Keiko;
- Yamamoto, Masayuki;
- Tanaka, Keiji;
- Mizushima, Noboru;
- Komatsu, Masaaki;
- Kopito, Ron R.
Publication type:
Article
Image-based genome-wide siRNA screen identifies selective autophagy factors.
Published in:
Nature, 2011, v. 480, n. 7375, p. 113, doi. 10.1038/nature10546
By:
- Orvedahl, Anthony;
- Jr, Rhea Sumpter;
- Xiao, Guanghua;
- Ng, Aylwin;
- Zou, Zhongju;
- Tang, Yi;
- Narimatsu, Masahiro;
- Gilpin, Christopher;
- Sun, Qihua;
- Roth, Michael;
- Forst, Christian V.;
- Wrana, Jeffrey L.;
- Zhang, Ying E.;
- Luby-Phelps, Katherine;
- Xavier, Ramnik J.;
- Xie, Yang;
- Levine, Beth
Publication type:
Article
Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions.
Published in:
PLoS Genetics, 2009, v. 5, n. 6, p. 1, doi. 10.1371/journal.pgen.1000534
By:
- Raychaudhuri, Soumya;
- Plenge, Robert M.;
- Rossin, Elizabeth J.;
- Ng, Aylwin C. Y.;
- Purcell, Shaun M.;
- Sklar, Pamela;
- Scolnick, Edward M.;
- Xavier, Ramnik J.;
- Altshuler, David;
- Daly, Mark J.
Publication type:
Article
A gene expression and systems pathway analysis of the effects of clozapine compared to haloperidol in the mouse brain implicates susceptibility genes for schizophrenia.
Published in:
Journal of Psychopharmacology, 2012, v. 26, n. 9, p. 1218, doi. 10.1177/0269881112450780
By:
- Rizig, Mie A;
- McQuillin, Andrew;
- Ng, Aylwin;
- Robinson, Michelle;
- Harrison, Andrew;
- Zvelebil, Marketa;
- Hunt, Steve P;
- Gurling, Hugh M
Publication type:
Article

Found: 20